Treatment of AIDS-associated progressive multifocal leukoencephalopathy with highly active antiretroviral therapy

AIDS

Volumn 12, Issue 18, 1998, Pages 2467-2472

  Miralles, Pilar ^a   Berenguer, Juan ^a   De Viedma, Darío García ^a   Padilla, Belén ^a   Cosin, Jaime ^a   De Quirós, Juan Carlos López Bernaldo ^a   Muñoz, Lucía ^a   Moreno, Santiago ^b   Bouza, Emilio ^a  

^a HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^b HOSPITAL MORALES MESEGUER   (Spain)

Author keywords

Antiretroviral therapy; Brain; Neurological; Opportunistic infections; Progressive multifocal leukoencephalopathy

Indexed keywords

ANTIRETROVIRUS AGENT; CD4 ANTIGEN; CYTARABINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ARTICLE; BRAIN BIOPSY; CEREBROSPINAL FLUID; CLINICAL ARTICLE; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; JC VIRUS; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; VIRUS LOAD;

EID: 0032564621     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199818000-00016     Document Type: Article

References (17)

1. Berger JR, Kaszovitz B, Post MJ, Dickinson G: Progressive multifocal leukoencephalopathy associated with human immuno-deficiency virus infection. A review of the literature with a report of sixteen cases. Ann Intern Med 1987, 107:78-87.
2. Fong IW, Toma E: The natural history of progressive multifocal leukoencephalopathy in patients with AIDS. Canadian PML Study Group. Clin Infect Dis 1995, 20:1305-1310.
3. Berger JR, Mucke L: Prolonged survival and partial recovery in AIDS-associated progressive multifocal leukoencephalopathy. Neurology 1188, 38:1060-1065.
4. Portegies P, Algra PR, Hollak CE, et al.: Response to cytarabine in progressive multifocal leucoencephalopathy in AIDS [letter]. Lancet 1991, 337:680-681.
5. Nicoli F, Chave B, Peragut JC, Gastaul K: Efficacy of cytarabine in progressive multifocal leucoencephalopathy in AIDS [letter]. Lancet 1942, 339:306.
6. Singer EJ, Stoner CL, Singer P, et al.: AIDS presenting as progressive multifocal leukoencephalopathy with clinical response to zidovudine. Acta Neurol Scand 1994, 90:443-447.
7. Centers for Disease Control and Prevention: Update: trends in AIDS incidence, deaths, and prevalence - United States, 1996. MMWR 1997, 46:165-173.
8. Hammer SM, Squires KE, Hughes MD, et al.: A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team. N Engl J Med 1997, 337:725-733.
9. Elliot B, Aromin I, Cold R, Flanigan T, Mileno M: 2.5 year remission of AIDS associated progressive multifocal leukoencephalopathy with combined antiretroviral therapy [letter]. Lancet 1997, 349:850.
10. Power C, Nath A, Aoki FY, Bigio MD: Remission of progressive multifocal leukoencephalopathy following splenectomy and antiretroviral therapy in a patient with HIV infection. N Engl J Med 1997, 336:661-662.
11. Baqi M, Kucharczyk W, Walmsley SL: Regression of progressive multifocal encephalopathy with highly active antiretroviral therapy. AIDS 1997, 11:1526-1527.
12. Garcia de Viedema D, Alonso R, Miralles P, et al.: A dual qualitative/quantitative nested-PCR for JCV detection in CSF: High potential for evaluation and monitoring of PML in AIDS patients receiving HAART. J Clin Microbiol 1999, [in press].
13. Moreno S, Miralles P, Diaz MD, et al.: Cytarabine therapy for progressive multifocal leukoencephalopathy in patients with AIDS. Clin Infect Dis 1996, 23:1066-1068.
14. Hall CD, Dafni U, Simpson D, et al.: Failure of cytarabine in progressive multifocal leukoencephalopathy associated with human immunodeficiency virus infection. N Engl J Med 1998, 338:1345-1351.
15. Tada H, Rappaport J, Lashgari M, Amini S, Wong-Staal F, Khalili K: Trans activation of the JC virus late promoter by the tat protein of type 1 human immunodeficiency virus in glial cells. Proc Natl Acad Sci USA 1990, 87:3479-3483.
16. Moret H, Guichard M, Matheron S, et al.: Virological diagnosis of progressive multifocal leukoencephalopathy: detection of JC virus DNA in cerebrospinal fluid and brain tissue of AIDS patients. J Clin Microbiol 1993, 31:3310-3313.
17. O'Dell MW, Sasson NL: Hemiparesis in HIV infection. Rehabilitation approach. Am J Phys Med Rehabil 1992, 71:291-296.