Dynamic changes in cerebral blood flow, O2 tension, and calculated cerebral metabolic rate of O2 during functional activation using oxygen phosphorescence quenching

Journal of Cerebral Blood Flow and Metabolism

Volumn 21, Issue 5, 2001, Pages 511-516

  Ances, Beau M ^a   Wilson, David F ^a   Greenberg, Joel H ^a   Detre, John A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cerebral blood flow; Cerebral metabolic rate of O2; Oxygen dependent phosphorescence quenching

Indexed keywords

OXYGEN;

ANIMAL EXPERIMENT; ARTICLE; BRAIN BLOOD FLOW; BRAIN METABOLISM; BRAIN OXYGEN CONSUMPTION; BRAIN OXYGEN TENSION; CALCULATION; CONTROLLED STUDY; ELECTROSTIMULATION; FOREFOOT; LASER DOPPLER FLOWMETRY; MALE; METABOLIC RATE; NONHUMAN; PHOSPHORESCENCE; PRIORITY JOURNAL; RAT; SOMATOSENSORY CORTEX;

EID: 0035022358     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-200105000-00005     Document Type: Article

References (49)

1. Glycolysis-induced discordance between glucose metabolic rates measured with radiolabeled fluorodeoxyglucose and glucose
2. Transcranial laser doppler mapping of activation flow coupling of the rat somatosensory cortex
3. Effects of variations in interstimulus interval on activation-flow coupling response and somatosensory evoked potentials with forepaw stimulation in the rat
4. Non-linearity of activation flow coupling and forepaw stimulation in the rat using laser-Doppler
5. Suprathreshold auditory cortex activation visualized by intrinsic signal optical imaging
6. Hypoxia increases velocity of blood flow through parenchymal microvascular systems in rat brain
7. A model for the coupling between cerebral blood flow and oxygen metabolism during neural stimulation
8. Dynamics of blood flow and oxygenation changes during brain activation: The balloon model
9. Calibrated functional MRI: Mapping the dynamics of oxidative metabolism
10. Signal averaged laser Doppler measurements of activation-flow coupling in the rat forepaw somatosensory cortex
11. Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects
12. Nonoxidative glucose consumption during focal physiologic neural activity
13. Dynamic uncoupling and recoupling of perfusion and oxidative metabolism during focal brain activation in man
14. Laser-Doppler assessment of brain microcirculation: Effect of systemic alterations
15. Cerebral glucose and energy metabolism, cerebral oxygen consumption, and blood flow in arterial hypoxaemia
16. Investigation of BOLD signal dependence on cerebral blood flow and oxygen consumption: The deoxyhemoglobin dilution model
17. Increased tricarboxylic acid cycle flux in rat brain during forepaw stimulation detected with IH[13C]NMR
18. Oxidative glucose metabolism in rat brain during single forepaw stimulation: A spatially localized IH[13C] nuclear magnetic resonance study
19. A model for the regulation of cerebral oxygen delivery
20. Dependence of oxygen delivery on blood flow in rat brain: A 7 tesla nuclear magnetic resonance study
21. 2 by multi-modal MRI at 7.0 T
22. The nitrous oxide method for the quantitative determination of cerebral blood flow in man: Theory, procedure, and normal values
23. Induced response to hypercapnia in the two-compartment total cerebral blood volume: Influence on brain vascular reserve and flow efficiency
24. Comparison of blood oxygenation and cerebral blood flow effects in fMRI: Estimation of relative oxygen consumption change
25. Cerebral oxygen and energy metabolism during and after 30 minutes of moderate hypoxia
26. Persistent resetting of the cerebral oxygen/glucose uptake ratio by brain activation: Evidence obtained with the Kety-Schmidt technique
27. Activation-induced resetting of cerebral oxygen and glucose uptake in the rat
28. Vascular imprints of neuronal activity: Relationships between the dynamics of cortical blood flow, oxygenation, and volume changes following sensory stimulation
29. 2 during rat forepaw stimulation
30. Stimulus specific increases of oxidative metabolism in human visual cortex
31. Blood flow structuring and its alterations in capillaries of the cerebral cortex
32. Functional brain mapping by blood oxygenation level-dependent contrast magnetic resonance imaging. A comparison of signal characteristics with a biophysical model
33. Lactate rise detected by IH NMR in human visual cortex during physiologic stimulation
34. Does mental activity change the oxidative metabolism of the brain?
35. On the regulation of the blood supply of the brain
36. Imaging of phosphorescence: A novel method for measuring oxygen distribution in perfused tissue
37. 31P magnetic resonance spectroscopy
38. Vibratory stimulation increases and decreases the regional cerebral blood flow and oxidative metabolism: A positron emission tomography (PET) study
39. Repeated measurements of cerebral blood flow in rats. Comparison between the hydrogen clearance method and laser Doppler flowmetry
40. Early temporal characteristics of cerebral blood flow and deoxyhemoglobin changes during somatosensory stimulation
41. The effects of mental activity on cerebral circulation and metabolism
42. Functional activation of cerebral blood flow and metabolism before and after global ischemia of rat brain
43. A mathematical model of cerebral blood flow chemical regulation-Part I: Diffusion processes
44. Increased cortical oxidative metabolism due to sensory stimulation: Implications for functional brain imaging
45. A versatile and sensitive method for measuring oxygen
46. The oxygen dependence of mitochondrial oxidative phosphorylation measured by a new optical method for measuring oxygen concentration
47. Oxygen distribution in isolated perfused liver observed by phosphorescence imaging
48. Oxygen solubility in normal human blood