Signal averaged laser Doppler measurements of activation-flow coupling in the rat forepaw somatosensory cortex

Brain Research

Volumn 796, Issue 1-2, 1998, Pages 91-98

  Detre, John A ^a   Ances, Beau M ^a   Takahashi, Kazushi ^a   Greenberg, Joel H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Flow metabolic coupling; Laser Doppler flowmetry; Somatosensory cortex

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE; BRAIN BLOOD FLOW; BRAIN METABOLISM; DIAGNOSTIC IMAGING; DIAGNOSTIC VALUE; ERYTHROCYTE; FOREFOOT; HYPERCAPNIA; LASER DOPPLER FLOWMETRY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPRODUCIBILITY; SOMATOSENSORY CORTEX;

ANIMALS; BLOOD FLOW VELOCITY; BRAIN MAPPING; CEREBROVASCULAR CIRCULATION; ELECTRIC STIMULATION; FORELIMB; LASER-DOPPLER FLOWMETRY; MALE; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL PROCESSING, COMPUTER-ASSISTED; SOMATOSENSORY CORTEX;

EID: 0032526816     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00322-9     Document Type: Article

References (39)

1. Bereczki D., Wei L., Otsuka T., Hans F.-J., Acuff V., Patlak C., Fenstermacher J. Hypercapnia slightly raises blood volume and sizably elevates flow velocity in brain microvessels. Am. J. Physiol. 264:1993;H1360-H1369. Heart Circ. Physiol. 33.
2. Binder J.R., Rao S.M., Hammeke T.A., Yetkin F.Z., Jesmanowicz A., Bandettini P.A., Wong E.C., Estkowski L.D., Goldstein M.D., Haughton V.M., Hyde J.M. Functional magnetic resonance imaging of human auditory cortex. Ann. Neurol. 35:1994;662-672.
3. Chen J.-L., Wei L., Bereczki D., Hans F.-J., Otsuka T., Finnegan W., Patlak C., Fenstermacher J. Slighlty altered permeability-surface area products imply some cerebral capillary recruitment during hypercapnia. Microvasc. Res. 48:1994;190-211.
4. Conrad B., Klingelhofer J. Dynamics of regional cerebral blood flow for various visual stimuli. Exp. Brain Res. 77:1989;437-441.
5. Dirangl U., Kaplan B., Jacewicz M., Pulsinelli W. Continuous measurements of cerebral blood flow by laser Doppler flowmetry in a rat stroke model. J. Cereb. Blood Flow Metab. 9(5):1989;589-596.
6. Eyre J., Essex T., Flecknell P., Bartholomew P., Sinclair J. A comparison of measurements of cerebral blood flow in the rabbit using laser Doppler spectroscopy and radionuclide labelled microspheres. Clin. Phys. Physiol. Meas. 9:1988;65-74.
7. Fahraeus R. The suspension stability of the blood. Physiol. Rev. 9:1929;241-274.
8. Fox P.T., Raichle M.E. Stimulus rate determines regional blood flow in striate cortex. Ann. Neurol. 17:1985;303-305.
9. Fox P.T., Raichle M.E. Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects. Proc. Natl. Acad. Sci. USA. 83:1986;1140-1144.
10. Grinvald A., Leike E., Frostig R.D., Gilbert C.D., Weisel T.N. Functional architecture of the cortex revealed by optical imaging of intrinsic signals. Nature. 324:1986;269-271.
11. Gyngell M.L., Bock C., Schmitz B., Hoehn-Berlage M., Hossman K.-A. Variation of functional MRI signal in response to frequency of somatosensory stimulation in α-chloralose anesthetized rats. Magn. Reson. Med. 36:1996;13-15.
12. Haberl R.ML.H., Marmarou A., Ellis E.F. Laser Doppler assessment of brain microcirculation: effect of systemic alterations. Am. J. Physiol. 256:1989;H1247-1254. (Heart Circ. Physiol. 25).
13. Hall R., Lindholm E. Organization of motor and somatosensory neocortex in the albino rat. Brain Res. 66:1974;23-38.
14. Hudetz A., Roman R., Harder D. Spontaneous flow oscillations in the cerebral cortex during acute changes in mean arterial pressure. J. Cereb. Blood Flow Metab. 12:1992;491-499.
15. Ibanez V., Deiber M.-P., Sadato N., Toro C., Grissom J., Woods R.P., Mazziotta J.C., Hallett M. Effects of stimulus rate on regional cerebral blood flow after median stimulation. Brain. 118:1995;1339-1351.
16. Keyeux A., Ochrymowicz-Bemelmans D., Charlier A. Induced response to hypercapnia in the two-component total cerebral blood volume: influence on brain vascular reserve and flow efficiency. J. Cereb. Blood Flow Metab. 15:1995;1121-1131.
17. Kwong K.K., Belliveau J.W., Chesler D.A., Goldberg I.E., Weisskoff R.M., Poncelet B.P., Kennedy D.N., Hoppel B.E., Cohen M.S., Turner R. Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc. Natl. Acad. Sci. USA. 89:1992;5675-5679.
18. Lindauer U., Villringer A., Dirnagl U. Characterization of the CBF response to somatosensory stimulation: the model and influence of anesthetics. Am. J. Physiol. 264:1993;H1223-H1288. (Heart Circ. Physiol. 33).
19. Lou H., Edvinsson L., Mackenzie E. The concept of coupling blood flow to brain function: revision required? Ann. Neurol. 22:1987;289-297.
20. Malonek D., Grinvald A. Interactions between electrical activity and cortical microcirculation revealed by imaging spectroscopy: implications for functional brain mapping. Science. 272:1996;551-554.
21. Mori S., Ngai A.C., Ko K.R., Winn H.R. A venous outflow method for continuously monitoring cerebral blood flow in the rat. Am. J. Physiol. 250:1986;H304-H312.
22. H. Nakagawa, S.-Z. Lin, D. Bereczecki, G. Gesztelyi, T. Otsuka, L. Wei, F.J. Hans, V.R. Acuff, J.-L. Chen, D. Pettigrew, C.S. Patlak, R.G. Blasberg, J.D. Fenstermacher, Blood volumes, hematocrits, and transit-times in parenchymal microvascular systems of the rat brain, in: D. Le Bihan (Ed.), Diffusion and Perfusion Magnetic Resonance Imaging, Raven Press, New York, 1995.
23. Narayan S.M., Esfahani P., Blood A.J., Sikkens L., Toga A.W. Functional increases in cerebral blood volume over somatosensory cortex. J. Cereb. Blood Flow Metab. 15:1995;754-765.
24. Ngai A., Ko K., Morii S., Winn H. Effect of sciatic nerve stimulation on pial arterioles in rats. Am. J. Physiol. 254:1988;H133-H139. (Heart Circ. Physiol. 23).
25. Ngai A., Meno J., Winn H. Simultaneous measurement of the pial arteriolar diameter and laser Doppler during somatosensory stimulation. J. Cereb. Blood Flow Metab. 15:1995;124-127.
26. Ngai A.C., Ko K.R., Morii S., Winn H.R. Effect of sciatic nerve stimulation on pial arterioles in rats. Am. J. Physiol. 254:1988;H133-H139. Heart Circ. Physiol. 23.
27. Northington F., Matherne G., Coleman S., Berne R. Sciatic nerve stimulation does not increase endogenous adenosine production in sensory-motor cortex. J. Cereb. Blood Flow Metab. 12:1992;835-843.
28. Ogawa S., Lee T.-M., Nayak A.S., Glunn P. Oxygenation-sensitive contrast in magnetic resonance image of rodent brain at high magnetic fields. Magn. Reson. Med. 14:1990;68-78.
29. Olesen J. Contralateral focal increase of cerebral blood flow in man during arm movement. Brain. 94:1971;737-756.
30. G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, Academic Press, New York, 1982.
31. Sato A., Uchida S., Yamauchi Y. A new method for continuous measurement of regional blood flow using laser Doppler flowmetry in a conscious rat. Neurosci. Lett. 175:1994;149-152.
32. Schmitz B., Boettinger B., Hossmann K. Hypercapnia enhances somatosensory activation of blood flow in rat. J. Cereb. Blood Flow Metab. 16(6):1996;1307-1311.
33. Sharphedhedinsson J., Harding H., Thoren P. Repeated measurements of cerebral blood flow in rats: comparison between the hydrogen clearance method and laser Doppler flowmetry. Acta Physiol. Scand. 134:1993;133-142.
34. Shockley R., LaManna J. The determination of rat cerebral cortical blood volume changes by capillary mean transit time analysis during hypoxia, hypercapnia and hyperventilation. Brain Res. 454:1988;170-178.
35. Sturznegger M., Newell D.W., Aaslid R. Visually evoked blood flow response assessed by simultaneous transcranial Doppler using flow velocity averaging. Stroke. 27:1996;2256-2261.
36. Todd M., Weeks J., Warner D. Cerebral blood flow, blood volume, and brain tissue hematocrit during isovolemic hemodilution with hetastarch rats. Am. J. Physiol. 263:1992;H75-H82. (Heart Circ Physiol. 32).
37. Ueki M., Linn F., Hossmann K.-A. Functional activation of cerebral blood flow and metabolism before and after global ischemia of rat brain. J. Cereb. Blood Flow Metab. 8:1988;486-494.
38. Villringer A., Dirnagl U. Coupling of brain activity and cerebral blood flow: basis of functional neuroimaging. Cereb. Brain Metab. Rev. 7:1995;240-276.
39. Yang X., Hyder F., Shulman R.G. Activation of single whisker barrel in rat localized by functional magnetic resonance imaging. Proc. Natl. Acad. Sci. USA. 93:1996;475-478.