Behavioral characterization of Co 134444 (3α-hydroxy-21-(1′-imidazolyl)-3β-methoxymethyl-5α- pregnan-20-one), a novel sedative-hypnotic neuroactive steroid

Psychopharmacology

Volumn 155, Issue 3, 2001, Pages 285-291

  Vanover, Kimberly E E ^a,c   Hogenkamp, Derk J ^a   Lan, Nancy C ^a   Gee, Kelvin W ^b   Carter, Richard B ^a  

^a Department of Pharmacokinetics and Drug Metabolism   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c ACADIA PHARMACEUTICALS INC   (United States)

Author keywords

Anticonvulsant; Anxiolytic; Ataxia; Drug discrimination; GABAA

Indexed keywords

3ALPHA HYDROXY 21 (1 IMIDAZOLYL) 3BETA METHOXYMETHYL 5ALPHA PREGNAN 20 ONE; 3ALPHA HYDROXY 21 (1' IMIDAZOLYL) 3BETA METHOXYMETHYL 5ALPHA PREGNAN 20 ONE; HYPNOTIC SEDATIVE AGENT; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; ATAXIA; CONTROLLED STUDY; CONVULSION; DISCRIMINATIVE STIMULUS; DRINKING; DRUG EFFICACY; ELECTROCONVULSIVE THERAPY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEDATION; TONIC SEIZURE; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; ANTICONVULSANTS; ATAXIA; BEHAVIOR, ANIMAL; CONVULSANTS; DISCRIMINATION (PSYCHOLOGY); DOSE-RESPONSE RELATIONSHIP, DRUG; DRINKING; ELECTROSHOCK; FEMALE; HYPNOTICS AND SEDATIVES; MALE; MICE; MUSCULOSKELETAL EQUILIBRIUM; PENTYLENETETRAZOLE; PREGNANOLONE; PUNISHMENT; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES;

EID: 0035017950     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130100695     Document Type: Article

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