Effects of leptin and corticosterone on the expression of corticotropin-releasing hormone, agouti-related protein, and proopiomelanocortin in the brain of ob/ob mouse

Neuroendocrinology

Volumn 73, Issue 4, 2001, Pages 227-236

  Arvaniti, Konstantinia ^a   Huang, Qingling ^a   Richard, Denis ^a,b  

^a LAVAL UNIVERSITY   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

Author keywords

Adrenal steroids; Adrenalectomy; Agouti related protein; Arcuate nucleus; Corticotropin releasing hormone; Food intake behavior; Leptin; Obesity; Paraventricular nucleus; Proopiomelanocortin

Indexed keywords

AGOUTI RELATED PROTEIN; CORTICOSTERONE; CORTICOTROPIN RELEASING FACTOR; LEPTIN; MESSENGER RNA; PROOPIOMELANOCORTIN;

ADRENALECTOMY; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR HYPOTHALAMUS; ARCUATE NUCLEUS; ARTICLE; BRAIN; CONTROLLED STUDY; DOWN REGULATION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADRENALECTOMY; ANIMALS; BRAIN CHEMISTRY; CORTICOSTERONE; CORTICOTROPIN-RELEASING HORMONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY METABOLISM; FEMALE; IN SITU HYBRIDIZATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LEPTIN; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; PRO-OPIOMELANOCORTIN; PROTEIN BIOSYNTHESIS; PROTEINS; RNA, ANTISENSE; RNA, MESSENGER; SULFUR RADIOISOTOPES;

EID: 0035014773     PISSN: 00283835     EISSN: None     Source Type: Journal    
DOI: 10.1159/000054639     Document Type: Article

References (47)

1. Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
2. Weight-reducing effects of the plasma protein encoded by the obese gene
3. Effects of the obese gene product on body weight regulation in ob/ob mice
4. Central regulation of appetite and autonomic activity by CRH, glucocorticoids and stress
5. The nature of the ponderostat: Hervey's hypothesis revived
6. Some metabolic and behavioral effects of adrenalectomy on obese Zucker rats
7. GDP binding to brown-adipose-tissue mitochondria of mice treated chronically with corticosterone
8. Corticosterone decreases nonshivering thermogenesis and increases lipid storage in brown adipose tissue
9. Leptin increases hypothalamic proopiomelanocortin mRNA expression in the rostral arcuate nucleus
10. Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice
11. Sympathetic activation of leptin via the ventromedial hypothalamus - Leptin-induced increase in catecholamine secretion
12. Physiological and anatomical circuitry between Agouti-related protein and leptin signaling
13. Obesity, diabetes and functions for proopiomelanocortin-derived peptides
14. Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
15. ART (protein product of agouti-related transcript) as an antagonist of MC-3 and MC-4 receptors
16. Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
17. Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons
18. Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice
19. Overexpression of Agrt leads to obesity in transgenic mice
20. Leptin affects food intake via CRF-receptor-mediated pathways
21. Hypothalamic corticotropin-releasing hormone is a mediator of the anorexigenic effect of leptin
22. Glucocorticoids reverse leptin effects on food intake and body fat in mice without increasing NPY mRNA
23. Effect of leptin on energy balance does not require the presence of intact adrenals
24. ob mice
25. Adrenalectomy reverses pre-existing obesity in adult genetically obese (ob/ob) mice
26. A complete protocol for in situ hybridization of messenger RNAs in brain and other tissues with radiolabeled single-stranded RNA probes
27. Role of leptin in the neuroendocrine response to fasting
28. Leptin inhibition of the hypothalamic-pituitary-adrenal axis in response to stress
29. Effects of leptin on corticotropin-releasing factor (CRF) synthesis and CRF neuron activation in the paraventricular hypothalamic nucleus of obese (ob/ob) mice
30. Effects of corticosterone on CRH mRNA and content in the bed nucleus of the stria terminalis: Comparison with the effects in the central nucleus of the amygdala and the paraventricular nucleus of the hypothalamus
31. Distributions of leptin receptor mRNA isoforms in the rat brain
32. Splice variants of the OB receptor gene are differentially expressed in brain and peripheral tissues of mice
33. Glucocorticoids as modulators in the control of feeding
34. The hypothalamic-pituitary-adrenal axis in obesity
35. Effects of food restriction and adrenalectomy in rats with VMH or PVH lesions
36. Leptin receptor mRNA identifies a subpopulation of neuropeptide Y neurons activated by fasting in rat hypothalamus
37. Glucocorticoid regulation of proopiomelanocortin messenger ribonucleic acid content of rat hypothalamus
38. Glucocorticoid regulation of hypothalamic proopiomelanocortin
39. Hypothalamic and genetic obesity in experimental animals: An autonomic and endocrine hypothesis
40. Genetically obese (ob/ob) mice are hypersensitive to glucocorticoid stimulation of feeding but dramatically resist glucocorticoid-induced weight loss
41. The role of neuropeptide Y in the antiobesity action of the obese gene product
42. The weight-reducing effect of an intracerebroventricular bolus injection of leptin in genetically obese fa/fa rats - Reduced sensitivity compared with lean animals
43. Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice
44. Localization of glucocorticoid receptor in neuropeptide Y-containing neurons in the arcuate nucleus of the rat hypothalamus
45. Regional differences in glucocorticoid receptor immunoreactivity among neuropeptide Y immunoreactive neurons of the rat brain