메뉴 건너뛰기




Volumn 48, Issue 4, 1999, Pages 828-833

Leptin receptor mrna identifies a subpopulation of neuropeptide y neurons activated by fasting in rat hypothalamus

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; LEPTIN RECEPTOR; MESSENGER RNA; NEUROPEPTIDE Y; PROOPIOMELANOCORTIN;

EID: 0032998652     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.48.4.828     Document Type: Article
Times cited : (290)

References (42)
  • 1
    • 0031578276 scopus 로고    scopus 로고
    • Neuroendocrine responses to starvation and weight loss
    • Schwartz MW, Seeley RJ: Neuroendocrine responses to starvation and weight loss. N Engl J Med 336:1802-1811, 1997
    • (1997) N Engl J Med , vol.336 , pp. 1802-1811
    • Schwartz, M.W.1    Seeley, R.J.2
  • 2
    • 0032548825 scopus 로고    scopus 로고
    • Obesity and the hypothalamus: Novel peptides for new pathways
    • Flier JS, Maratos-Flier E: Obesity and the hypothalamus: novel peptides for new pathways. Cell 92:437-440, 1998
    • (1998) Cell , vol.92 , pp. 437-440
    • Flier, J.S.1    Maratos-Flier, E.2
  • 3
    • 0025543712 scopus 로고
    • Evidence that neuropeptide Y elicits eating by acting in the caudolateral paraventricular/perifornical hypothalamus
    • Stanley BG, Magdalin W, Leibowitz SF: Evidence that neuropeptide Y elicits eating by acting in the caudolateral paraventricular/perifornical hypothalamus. Ann N Y Acad Sci 611:489-490, 1990
    • (1990) Ann N Y Acad Sci , vol.611 , pp. 489-490
    • Stanley, B.G.1    Magdalin, W.2    Leibowitz, S.F.3
  • 5
    • 0026632281 scopus 로고
    • Effect of fasting on regional levels of neuropeptide Y mRNA and insulin receptors in the rat hypothalamus: An autoradiographic study
    • Marks JL, Li M, Schwartz MW, Porte DJ, Baskin DG: Effect of fasting on regional levels of neuropeptide Y mRNA and insulin receptors in the rat hypothalamus: an autoradiographic study. Mol Cell Neurosci 3:199-205, 1992
    • (1992) Mol Cell Neurosci , vol.3 , pp. 199-205
    • Marks, J.L.1    Li, M.2    Schwartz, M.W.3    Porte, D.J.4    Baskin, D.G.5
  • 7
    • 0025721025 scopus 로고
    • Neuropeptide Y secretion increases in the paraventricular nucleus in association with increased appetite for food
    • Kalra SP, Dube MG, Sahu A, Phelps CP, Kalra PS: Neuropeptide Y secretion increases in the paraventricular nucleus in association with increased appetite for food. Proc Natl Acad Sci U S A 88:10931-10335, 1991
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 10931-11035
    • Kalra, S.P.1    Dube, M.G.2    Sahu, A.3    Phelps, C.P.4    Kalra, P.S.5
  • 8
    • 0031733326 scopus 로고    scopus 로고
    • Effect of fasting and leptin deficiency on hypothalamic neuropeptide Y gene transcription in vivo revealed by expression of a lacZ, reporter gene
    • Schwartz MW, Erickson JC, Baskin DG, Palmiter RD: Effect of fasting and leptin deficiency on hypothalamic neuropeptide Y gene transcription in vivo revealed by expression of a lacZ, reporter gene. Endocrinology 139:2629-2635, 1998
    • (1998) Endocrinology , vol.139 , pp. 2629-2635
    • Schwartz, M.W.1    Erickson, J.C.2    Baskin, D.G.3    Palmiter, R.D.4
  • 9
    • 0032130554 scopus 로고    scopus 로고
    • Colocalization of agouti-related protein and neuropeptide Y in arcuate nucleus neurons activated by fasting
    • Hahn TM, Breininger JF, Baskin DG, Schwartz MW: Colocalization of agouti-related protein and neuropeptide Y in arcuate nucleus neurons activated by fasting. Nat Neurosci 1:271-272, 1998
    • (1998) Nat Neurosci , vol.1 , pp. 271-272
    • Hahn, T.M.1    Breininger, J.F.2    Baskin, D.G.3    Schwartz, M.W.4
  • 10
    • 0030614331 scopus 로고    scopus 로고
    • Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
    • Fan W, Boston BA, Kesterson RA, Hruby VJ, Cone RD: Role of melanocortinergic neurons in feeding and the agouti obesity syndrome. Nature 385:165-168, 1997
    • (1997) Nature , vol.385 , pp. 165-168
    • Fan, W.1    Boston, B.A.2    Kesterson, R.A.3    Hruby, V.J.4    Cone, R.D.5
  • 16
    • 0029048408 scopus 로고
    • Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
    • Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P: Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269:546-549, 1995
    • (1995) Science , vol.269 , pp. 546-549
    • Campfield, L.A.1    Smith, F.J.2    Guisez, Y.3    Devos, R.4    Burn, P.5
  • 18
    • 0029763177 scopus 로고    scopus 로고
    • The weight-reducing effect of an intracerebroventricular bolus injection of leptin in genetically obese fa/fa rats: Reduced sensitivity compared with lean animals
    • Cusin I, Rohner-Jeanrenaud F, StrickerKrongrad A, Jeanrenaud B: The weight-reducing effect of an intracerebroventricular bolus injection of leptin in genetically obese fa/fa rats: reduced sensitivity compared with lean animals. Diabetes 45:1446-1451, 1996
    • (1996) Diabetes , vol.45 , pp. 1446-1451
    • Cusin, I.1    Rohner-Jeanrenaud, F.2    StrickerKrongrad, A.3    Jeanrenaud, B.4
  • 20
    • 0030942844 scopus 로고    scopus 로고
    • The leptin receptor
    • Tartaglia LA: The leptin receptor. J Biol Chem 272:6093-6096, 1997
    • (1997) J Biol Chem , vol.272 , pp. 6093-6096
    • Tartaglia, L.A.1
  • 22
    • 0029895233 scopus 로고    scopus 로고
    • Localization of leptin receptor mRNA and the long-form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization
    • Mercer JG, Hoggard N, Williams LM, Lawrence CB, Hannah LT, Trayhurn P: Localization of leptin receptor mRNA and the long-form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization. FEBS Lett 387:113-116, 1996
    • (1996) FEBS Lett , vol.387 , pp. 113-116
    • Mercer, J.G.1    Hoggard, N.2    Williams, L.M.3    Lawrence, C.B.4    Hannah, L.T.5    Trayhurn, P.6
  • 23
    • 0031010408 scopus 로고    scopus 로고
    • Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues
    • Fei H, Okano HJ, Li C, Lee G, Zhao C, Darnell R, Friedman JM: Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues. Proc Natl Acad Sci U S A 94:7001-7005, 1997
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 7001-7005
    • Fei, H.1    Okano, H.J.2    Li, C.3    Lee, G.4    Zhao, C.5    Darnell, R.6    Friedman, J.M.7
  • 24
    • 0031895877 scopus 로고    scopus 로고
    • Increased expression of mRNA for the long form of the leptin receptor in the hypothalamus is associated with leptin hypersensitivity and fasting
    • Baskin DG, Seeley RJ, Kuijper JL, LoK S, Weigle DS, Erickson JC, Palmiter RD, Schwartz MW: Increased expression of mRNA for the long form of the leptin receptor in the hypothalamus is associated with leptin hypersensitivity and fasting. Diabetes 47:538-544, 1998
    • (1998) Diabetes , vol.47 , pp. 538-544
    • Baskin, D.G.1    Seeley, R.J.2    Kuijper, J.L.3    Lo, K.S.4    Weigle, D.S.5    Erickson, J.C.6    Palmiter, R.D.7    Schwartz, M.W.8
  • 25
    • 0030928715 scopus 로고    scopus 로고
    • Pro-opiomelanocortin neurons are direct targets for leptin in the hypothalamus
    • Cheung CC, Clifton DK, Steiner RA: Pro-opiomelanocortin neurons are direct targets for leptin in the hypothalamus. Endocrinology 138:4489-4492, 1997
    • (1997) Endocrinology , vol.138 , pp. 4489-4492
    • Cheung, C.C.1    Clifton, D.K.2    Steiner, R.A.3
  • 26
    • 0030729210 scopus 로고    scopus 로고
    • Regulation of hypothalamic pro-opiomelanocortin mRNA by leptin in ob/ob mice
    • Thornton JE, Cheung CC, Clifton DK, Steiner RA: Regulation of hypothalamic pro-opiomelanocortin mRNA by leptin in ob/ob mice. Endocrinology 138:5063-5066, 1997
    • (1997) Endocrinology , vol.138 , pp. 5063-5066
    • Thornton, J.E.1    Cheung, C.C.2    Clifton, D.K.3    Steiner, R.A.4
  • 28
    • 0031888157 scopus 로고    scopus 로고
    • Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting in ob/ob and db/db mice, but is stimulated by leptin
    • Mizuno TM, Kloopoulos SP, Bergen HT, Roberts JL, Priest CA, Mobbs CV: Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting in ob/ob and db/db mice, but is stimulated by leptin. Diabetes 47:294-297, 1998
    • (1998) Diabetes , vol.47 , pp. 294-297
    • Mizuno, T.M.1    Kloopoulos, S.P.2    Bergen, H.T.3    Roberts, J.L.4    Priest, C.A.5    Mobbs, C.V.6
  • 30
    • 0023917334 scopus 로고
    • Rat neuropeptide Y precursor gene expression, mRNA structure, tissue distribution, and regulation by glucocorticoids, cyclic AMP, and phorbol ester
    • Higuchi H, Yang HY, Sabol SL: Rat neuropeptide Y precursor gene expression, mRNA structure, tissue distribution, and regulation by glucocorticoids, cyclic AMP, and phorbol ester. J Biol Chem 263:6288-6295, 1988
    • (1988) J Biol Chem , vol.263 , pp. 6288-6295
    • Higuchi, H.1    Yang, H.Y.2    Sabol, S.L.3
  • 31
    • 0020664262 scopus 로고
    • Complete amino acid sequence of mouse pro-opiomelanocortin derived from the nucleotide sequence of pro-opiomelanocortin cDNA
    • Uhler M, Herbert E: Complete amino acid sequence of mouse pro-opiomelanocortin derived from the nucleotide sequence of pro-opiomelanocortin cDNA. J Biol chem 258:257-201, 1983
    • (1983) J Biol Chem , vol.258 , pp. 257-261
    • Uhler, M.1    Herbert, E.2
  • 34
    • 0030455391 scopus 로고    scopus 로고
    • Effects of nutritional status and aging on leptin gene expression in mice: Importance of glucose
    • Mizuno T, Bergen H, Kleopoulos S, Bauman WA, Mobbs CV: Effects of nutritional status and aging on leptin gene expression in mice: importance of glucose. Horm Metab Res 28:679-684, 1996
    • (1996) Horm Metab Res , vol.28 , pp. 679-684
    • Mizuno, T.1    Bergen, H.2    Kleopoulos, S.3    Bauman, W.A.4    Mobbs, C.V.5
  • 35
    • 0027319108 scopus 로고
    • Increased neuropeptide Y messenger ribonucleic acid (mRNA) and decreased neurotensin mRNA in the hypothalamus of the obese (ob/ob) mouse
    • Wilding JPH, Gilbey SG, Bailey CJ, Batt RAL, Williams G, Ghatei MA, Bloom SR: Increased neuropeptide Y messenger ribonucleic acid (mRNA) and decreased neurotensin mRNA in the hypothalamus of the obese (ob/ob) mouse. Endocrinology 132:1939-1944, 1993
    • (1993) Endocrinology , vol.132 , pp. 1939-1944
    • Wilding, J.P.H.1    Gilbey, S.G.2    Bailey, C.J.3    Batt, R.A.L.4    Williams, G.5    Ghatei, M.A.6    Bloom, S.R.7
  • 36
    • 0025072899 scopus 로고
    • Increased hypothalamic content of preproneuropeptide Y messenger ribonucleic acid in genetically obese Zucker rats and its regulation by food deprivation
    • Sanacora G, Kershaw M, Kinkelstein JA, White JD: Increased hypothalamic content of preproneuropeptide Y messenger ribonucleic acid in genetically obese Zucker rats and its regulation by food deprivation. Endocrinology 127:730-737, 1990
    • (1990) Endocrinology , vol.127 , pp. 730-737
    • Sanacora, G.1    Kershaw, M.2    Kinkelstein, J.A.3    White, J.D.4
  • 38
    • 0031906674 scopus 로고    scopus 로고
    • Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei
    • Elmquist JK, Ahima RS, Elias CF, Flier JS, Saper CB: Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei. Proc Natl Acad Sci U S A 95:741-746, 1998
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 741-746
    • Elmquist, J.K.1    Ahima, R.S.2    Elias, C.F.3    Flier, J.S.4    Saper, C.B.5
  • 39
    • 0031764893 scopus 로고    scopus 로고
    • Evidence suggesting that galanin (GAL), melanin-concentrating hormone (MCH), neurotensin (NT), pro-opiomelanocortin (POMC), and neuropeptide Y (NPY) are targets of leptin signaling in the hypothalamus
    • Sahu A: Evidence suggesting that galanin (GAL), melanin-concentrating hormone (MCH), neurotensin (NT), pro-opiomelanocortin (POMC), and neuropeptide Y (NPY) are targets of leptin signaling in the hypothalamus. Endocrinology 139:795-798, 1998
    • (1998) Endocrinology , vol.139 , pp. 795-798
    • Sahu, A.1
  • 40
    • 0031824260 scopus 로고    scopus 로고
    • Arcuate nucleus ablation prevents resting-induced suppression of proTRH mRNA in the hypothalamic paraventricular nucleus
    • Légrádi G, Emerson CH, Ahima RS, Rand WM, Flier JS, Lechan RM: Arcuate nucleus ablation prevents resting-induced suppression of proTRH mRNA in the hypothalamic paraventricular nucleus. Neuroendocrinology 68:89-97, 1998
    • (1998) Neuroendocrinology , vol.68 , pp. 89-97
    • Légrádi, G.1    Emerson, C.H.2    Ahima, R.S.3    Rand, W.M.4    Flier, J.S.5    Lechan, R.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.