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Volumn 139, Issue 4, 1998, Pages 1524-1532

Effects of leptin on corticotropin-releasing factor (CRF) synthesis and CRF neuron activation in the paraventricular hypothalamic nucleus of obese (ob/ob) mice

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTERONE; CORTICOTROPIN RELEASING FACTOR; LEPTIN; MESSENGER RNA; NEUROPEPTIDE Y; PROTEIN C FOS; R MULEPTIN; UNCLASSIFIED DRUG;

EID: 0031791643     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.4.5889     Document Type: Article
Times cited : (138)

References (50)
  • 1
    • 0030467446 scopus 로고    scopus 로고
    • The OB protein (leptin) pathway - A link between adipose tissue mass and central neural networks
    • Campfield LA, Smith FJ, Burn P 1996 The OB protein (leptin) pathway - A link between adipose tissue mass and central neural networks. Horm Metab Res 28:619-632
    • (1996) Horm Metab Res , vol.28 , pp. 619-632
    • Campfield, L.A.1    Smith, F.J.2    Burn, P.3
  • 3
    • 0030277372 scopus 로고    scopus 로고
    • New insights into the development of obesity: Obese genes and the leptin system
    • Trayhum P 1996 New insights into the development of obesity: obese genes and the leptin system. Proc Nutr Soc 55:783-791
    • (1996) Proc Nutr Soc , vol.55 , pp. 783-791
    • Trayhum, P.1
  • 5
    • 0029048408 scopus 로고
    • Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
    • Campfield LA, Smith FJ, Cuisez Y, Devos R, Burn P1995 Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269:546-549
    • (1995) Science , vol.269 , pp. 546-549
    • Campfield, L.A.1    Smith, F.J.2    Cuisez, Y.3    Devos, R.4    Burn, P.5
  • 7
    • 0029939065 scopus 로고    scopus 로고
    • Decreased food intake does not completely account for adiposity reduction after ob protein infusion
    • Levin N, Nelson C, Gurney A, Vandlen R, Desauvage F 1996 Decreased food intake does not completely account for adiposity reduction after ob protein infusion. Proc Natl Acad Sci USA 93:1726-1730
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1726-1730
    • Levin, N.1    Nelson, C.2    Gurney, A.3    Vandlen, R.4    Desauvage, F.5
  • 9
    • 0029895233 scopus 로고    scopus 로고
    • Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hy-bridization
    • Mercer JG, Hoggard N, Williams LM, Lawrence CB, Hannah LT, Trayhurn P 1996 Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hy-bridization. FEBS Lett 387:113-116
    • (1996) FEBS Lett , vol.387 , pp. 113-116
    • Mercer, J.G.1    Hoggard, N.2    Williams, L.M.3    Lawrence, C.B.4    Hannah, L.T.5    Trayhurn, P.6
  • 11
    • 0031040784 scopus 로고    scopus 로고
    • Regulation of leptin receptor and NPY gene expression in hypothalamus of leptin-treated obese (ob/ob) and cold-exposed lean mice
    • Mercer JG, Moar KM, Rayner DV, Trayhurn P, Hoggard N 1997 Regulation of leptin receptor and NPY gene expression in hypothalamus of leptin-treated obese (ob/ob) and cold-exposed lean mice. FEBS Lett 402:185-188
    • (1997) FEBS Lett , vol.402 , pp. 185-188
    • Mercer, J.G.1    Moar, K.M.2    Rayner, D.V.3    Trayhurn, P.4    Hoggard, N.5
  • 14
    • 0024992271 scopus 로고
    • Central effects of CRF on metabolism and energy balance
    • Rothwell NJ 1990 Central effects of CRF on metabolism and energy balance. Neurosci Biobehav Rev 14:263-271
    • (1990) Neurosci Biobehav Rev , vol.14 , pp. 263-271
    • Rothwell, N.J.1
  • 15
    • 0027755325 scopus 로고
    • Involvement of corticotropin-releasing factor in the control of food intake and energy expenditure
    • Richard D 1993 Involvement of corticotropin-releasing factor in the control of food intake and energy expenditure. Ann NY Acad Sci 697:155-172
    • (1993) Ann NY Acad Sci , vol.697 , pp. 155-172
    • Richard, D.1
  • 16
    • 0030807780 scopus 로고    scopus 로고
    • Functional activation of CRH neurons and expression of the genes encoding CRH and its receptors in food-deprived lean (Fa/?) and obese (fa/fa) Zucker rats
    • Timofeeva E, Richard D 1997 Functional activation of CRH neurons and expression of the genes encoding CRH and its receptors in food-deprived lean (Fa/?) and obese (fa/fa) Zucker rats. Neuroendocrinology 66:327-340
    • (1997) Neuroendocrinology , vol.66 , pp. 327-340
    • Timofeeva, E.1    Richard, D.2
  • 17
    • 0028035069 scopus 로고
    • Elevated neuronal c-Fos-like immunoreactivity and messenger ribonucleic acid (mRNA) in genetically obese (ob/ob) mice
    • Mistry AM, Helferich W, Romsos DR 1994 Elevated neuronal c-Fos-like immunoreactivity and messenger ribonucleic acid (mRNA) in genetically obese (ob/ob) mice. Brain Res 666:53-60
    • (1994) Brain Res , vol.666 , pp. 53-60
    • Mistry, A.M.1    Helferich, W.2    Romsos, D.R.3
  • 18
    • 0024463970 scopus 로고
    • A complete protocol for in situ hybridization of messenger RNAs in brain and other tissues with radiolabeled single-stranded RNA probes
    • Simmons DM, Arriza JL, Swanson LW 1989 A complete protocol for in situ hybridization of messenger RNAs in brain and other tissues with radiolabeled single-stranded RNA probes. J Histotechnol 12:169-181
    • (1989) J Histotechnol , vol.12 , pp. 169-181
    • Simmons, D.M.1    Arriza, J.L.2    Swanson, L.W.3
  • 20
    • 0014103645 scopus 로고
    • Some studies of the protein-binding of steroids and their application to the routine micro and ultramicro measurement of various steroids in body fluids by competitive protein-binding radioassays
    • Murphy BEP 1967 Some studies of the protein-binding of steroids and their application to the routine micro and ultramicro measurement of various steroids in body fluids by competitive protein-binding radioassays. J Clin Endocrinol Metab 27:973-980
    • (1967) J Clin Endocrinol Metab , vol.27 , pp. 973-980
    • Murphy, B.E.P.1
  • 21
    • 0027309213 scopus 로고
    • c-Fos and related immediate early gene products as markers of activity in neuroendocrine systems
    • Hoffman GE, Smith MS, Verbalis JG 1993 c-Fos and related immediate early gene products as markers of activity in neuroendocrine systems. Front Neuroendocrinol 14:173-213
    • (1993) Front Neuroendocrinol , vol.14 , pp. 173-213
    • Hoffman, G.E.1    Smith, M.S.2    Verbalis, J.G.3
  • 22
    • 0028860249 scopus 로고
    • Fos: An immediate-early transcription factor in neurons
    • Curran T, Morgan JI 1995 Fos: an immediate-early transcription factor in neurons, J Neurobiol 26:403-412
    • (1995) J Neurobiol , vol.26 , pp. 403-412
    • Curran, T.1    Morgan, J.I.2
  • 24
    • 0028969667 scopus 로고
    • The role of corticotropin-releasing factor and interleukin-1 in the regulation of neurons controlling reproductive functions
    • Rivest S, Rivier C 1995 The role of corticotropin-releasing factor and interleukin-1 in the regulation of neurons controlling reproductive functions. Endoer Rev 16:177-199
    • (1995) Endoer Rev , vol.16 , pp. 177-199
    • Rivest, S.1    Rivier, C.2
  • 25
    • 0027131719 scopus 로고
    • A comparison of two immediate-early genes, c-fos and NGFI-B, as markers for functional activation in stress-related neuroendocrine circuitry
    • Chan RKW, Brown ER, Ericsson A, Kovacs KJ, Sawchenko PE 1993 A comparison of two immediate-early genes, c-fos and NGFI-B, as markers for functional activation in stress-related neuroendocrine circuitry. J Neurosci 13:5126-5138
    • (1993) J Neurosci , vol.13 , pp. 5126-5138
    • Chan, R.K.W.1    Brown, E.R.2    Ericsson, A.3    Kovacs, K.J.4    Sawchenko, P.E.5
  • 26
    • 0028036303 scopus 로고
    • Proto-oncogene c-fos and the regulation of vasopressin gene expression during dehydration
    • Ding JM, Carver WC, Terracio L, Buggy J 1994 Proto-oncogene c-fos and the regulation of vasopressin gene expression during dehydration. Mol Brain Res 21:247-255
    • (1994) Mol Brain Res , vol.21 , pp. 247-255
    • Ding, J.M.1    Carver, W.C.2    Terracio, L.3    Buggy, J.4
  • 28
    • 0028953834 scopus 로고
    • Immune challenge and immobilization stress induce transcription of the gene encoding the CRF receptor in selective nuclei of the rat hypothalamus
    • Rivest S, Laflamme N, Nappi RE 1995 Immune challenge and immobilization stress induce transcription of the gene encoding the CRF receptor in selective nuclei of the rat hypothalamus. J Neurosci 15:2680-2695
    • (1995) J Neurosci , vol.15 , pp. 2680-2695
    • Rivest, S.1    Laflamme, N.2    Nappi, R.E.3
  • 29
    • 0026466972 scopus 로고
    • The 5-hydroxytryptamine agonist fenfluramine increases Fos-like immunoreactivity in the brain
    • Richard D, Rivest S, Rivier C 1992 The 5-hydroxytryptamine agonist fenfluramine increases Fos-like immunoreactivity in the brain. Brain Res 594:131-137
    • (1992) Brain Res , vol.594 , pp. 131-137
    • Richard, D.1    Rivest, S.2    Rivier, C.3
  • 30
    • 0029868447 scopus 로고    scopus 로고
    • Effect of dexfenfluramine on the transcriptional activation of CRF and its type 1 receptor within the paraventricular nucleus of the rat hypothalamus
    • Laflamme N, Bovetto S, Richard D, Rivest S 1996 Effect of dexfenfluramine on the transcriptional activation of CRF and its type 1 receptor within the paraventricular nucleus of the rat hypothalamus. Br J Pharmacol 117:1021-1034
    • (1996) Br J Pharmacol , vol.117 , pp. 1021-1034
    • Laflamme, N.1    Bovetto, S.2    Richard, D.3    Rivest, S.4
  • 31
    • 0026643469 scopus 로고
    • Rapid regulation of corticotropin-releasing hormone gene transcription in vivo
    • Herman JP, Schafer MKH, Thompson RC, Watson SJ 1992 Rapid regulation of corticotropin-releasing hormone gene transcription in vivo. Mol Endocrinol 6:1061-1069
    • (1992) Mol Endocrinol , vol.6 , pp. 1061-1069
    • Herman, J.P.1    Schafer, M.K.H.2    Thompson, R.C.3    Watson, S.J.4
  • 32
    • 0030070524 scopus 로고    scopus 로고
    • Sequence of stress-induced alterations in indices of synaptic and transcriptional activation in parvocellular neurosecretory neurons
    • Kovacs KJ, Sawchenko PE 1996 Sequence of stress-induced alterations in indices of synaptic and transcriptional activation in parvocellular neurosecretory neurons. J Neurosci 16:262-273
    • (1996) J Neurosci , vol.16 , pp. 262-273
    • Kovacs, K.J.1    Sawchenko, P.E.2
  • 33
    • 0027094116 scopus 로고
    • Dysregulation of the hypothalamus-pituitary-adrenal axis in male and female, genetically obese (ob/ob) mice
    • Mcginnis R, Walker J, Margules D, Aird F, Redei E 1992 Dysregulation of the hypothalamus-pituitary-adrenal axis in male and female, genetically obese (ob/ob) mice. J Neuroendocrinol 4:765-771
    • (1992) J Neuroendocrinol , vol.4 , pp. 765-771
    • Mcginnis, R.1    Walker, J.2    Margules, D.3    Aird, F.4    Redei, E.5
  • 34
  • 35
    • 0015748455 scopus 로고
    • The effect of adrenalectomy on the development of the obese-hyperglycemic syndrome in ob/ob mice
    • Solomon J, Mayer J 1973 The effect of adrenalectomy on the development of the obese-hyperglycemic syndrome in ob/ob mice. Endocrinology 93:510-513
    • (1973) Endocrinology , vol.93 , pp. 510-513
    • Solomon, J.1    Mayer, J.2
  • 36
    • 0018611987 scopus 로고
    • Effect of adrenalectomy on obese 'fatty' rats
    • York DA, Godbole V 1979 Effect of adrenalectomy on obese 'fatty' rats. Horm Metab Res 11:646
    • (1979) Horm Metab Res , vol.11 , pp. 646
    • York, D.A.1    Godbole, V.2
  • 37
    • 0023010762 scopus 로고
    • Some metabolic and behavioral effects of adrenalectomy on obese Zucker rats
    • Castonguay TW, Dallman MF, Stem JS 1986 Some metabolic and behavioral effects of adrenalectomy on obese Zucker rats. Am J Physiol 251:R923-R933
    • (1986) Am J Physiol , vol.251
    • Castonguay, T.W.1    Dallman, M.F.2    Stem, J.S.3
  • 38
    • 0023357780 scopus 로고
    • Energy balance in rats with obesity-producing hypothalamic knife cuts: Effects of adrenalectomy
    • Romsos DR, Vander Tuig JG, Kemer J, Grogan CK 1987 Energy balance in rats with obesity-producing hypothalamic knife cuts: effects of adrenalectomy. J Nutr 117:1121-1128
    • (1987) J Nutr , vol.117 , pp. 1121-1128
    • Romsos, D.R.1    Vander Tuig, J.G.2    Kemer, J.3    Grogan, C.K.4
  • 40
    • 0024456675 scopus 로고
    • Adrenalectomy prevents obesity in glutamate-treated mice
    • Tokuyama K, Himms-Hagen J 1989 Adrenalectomy prevents obesity in glutamate-treated mice. Am J Physiol 257:E139-E144
    • (1989) Am J Physiol , vol.257
    • Tokuyama, K.1    Himms-Hagen, J.2
  • 41
    • 0026542149 scopus 로고
    • Adrenalectomy attenuates the effect of chemical castration on energy balance in rats
    • Ouerghi D, Rivest S, Richard D 1992 Adrenalectomy attenuates the effect of chemical castration on energy balance in rats. J Nutr 122:369-373
    • (1992) J Nutr , vol.122 , pp. 369-373
    • Ouerghi, D.1    Rivest, S.2    Richard, D.3
  • 42
    • 0029847171 scopus 로고    scopus 로고
    • The paraventricular nucleus of the hypothalamus and the functional neuroanatomy of visceromotor responses to stress
    • Sawchenko PE, Brown ER, Chan RKW, Ericsson A, Li HY, Roland BL, Kovacs KJ 1996 The paraventricular nucleus of the hypothalamus and the functional neuroanatomy of visceromotor responses to stress. Progr Brain Res 107:201-222
    • (1996) Progr Brain Res , vol.107 , pp. 201-222
    • Sawchenko, P.E.1    Brown, E.R.2    Chan, R.K.W.3    Ericsson, A.4    Li, H.Y.5    Roland, B.L.6    Kovacs, K.J.7
  • 43
    • 0031015517 scopus 로고    scopus 로고
    • Neurocircuitry of stress: Central control of the hypothalamo-pituitary-adrenocortical axis
    • Herman JP, Cullinan WE 1997 Neurocircuitry of stress: central control of the hypothalamo-pituitary-adrenocortical axis. Trends Neurosci 20:78-84
    • (1997) Trends Neurosci , vol.20 , pp. 78-84
    • Herman, J.P.1    Cullinan, W.E.2
  • 44
  • 46
    • 0025038674 scopus 로고
    • Altered expression of hypothalamic neuropeptide mRNAs in food restricted and food-deprived rats
    • Brady LS, Smith MA, Gold PW, Herkenham M 1990 Altered expression of hypothalamic neuropeptide mRNAs in food restricted and food-deprived rats. Neuroendocrinology 52:441-447
    • (1990) Neuroendocrinology , vol.52 , pp. 441-447
    • Brady, L.S.1    Smith, M.A.2    Gold, P.W.3    Herkenham, M.4
  • 47
    • 0023550611 scopus 로고
    • Neuropeptide Y administration acutely increases hypothalamic corticotropin-releasing factor immunoreactivity: Lack of effect in other brain regions
    • Haas DA, George SR 1987 Neuropeptide Y administration acutely increases hypothalamic corticotropin-releasing factor immunoreactivity: lack of effect in other brain regions. Life Sci 41:2725-2731
    • (1987) Life Sci , vol.41 , pp. 2725-2731
    • Haas, D.A.1    George, S.R.2
  • 48
    • 0027264008 scopus 로고
    • Neuropeptide-Y increases the Corticotropin-Releasing factor messenger ribonucleic acid level in the rat hypothalamus
    • Suda T, Tozawa F, Iwai I, Sato Y, Sumitomo T, Nakano Y, Yamada M, Demura H 1993 Neuropeptide-Y increases the Corticotropin-Releasing factor messenger ribonucleic acid level in the rat hypothalamus. Mol Brain Res 18:311-315
    • (1993) Mol Brain Res , vol.18 , pp. 311-315
    • Suda, T.1    Tozawa, F.2    Iwai, I.3    Sato, Y.4    Sumitomo, T.5    Nakano, Y.6    Yamada, M.7    Demura, H.8
  • 49
    • 0028506528 scopus 로고
    • Central nervous system and peripheral abnormalities: Clues to the understanding of obesity and NIDDM
    • Jeanrenaud B 1994 Central nervous system and peripheral abnormalities: clues to the understanding of obesity and NIDDM. Diabetologia 37:S169-S178
    • (1994) Diabetologia , vol.37
    • Jeanrenaud, B.1
  • 50
    • 0029763177 scopus 로고    scopus 로고
    • The weight-reducing effect of an intracerebroventricular bolus injection of leptin in genetically obese falfa rats - Reduced sensitivity compared with lean animals
    • Cusin I, Rohner-Jeanrenaud F, Stricker-Krongrad A, Jeanrenaud B 1996 The weight-reducing effect of an intracerebroventricular bolus injection of leptin in genetically obese falfa rats - reduced sensitivity compared with lean animals. Diabetes 45:1446-1451
    • (1996) Diabetes , vol.45 , pp. 1446-1451
    • Cusin, I.1    Rohner-Jeanrenaud, F.2    Stricker-Krongrad, A.3    Jeanrenaud, B.4


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