Attenuated glycogenolysis reduces glycolytic catabolite accumulation during ischemia in preconditioned rat hearts

Circulation Research

Volumn 79, Issue 3, 1996, Pages 435-446

  Weiss, Robert G ^a   De Albuquerque, Cicero P ^a   Vandegaer, Koenraad ^a   Chacko, V P ^a   Gerstenblith, Gary ^a  

^a JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

carbon 13 nuclear magnetic resonance; glycogen; glycolysis; lactate; phosphorylase

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE; GLUCOSE 6 PHOSPHATE; GLYCOGEN; GLYCOGEN PHOSPHORYLASE; LACTIC ACID;

ANIMAL TISSUE; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL PH; CONTROLLED STUDY; GLUCOSE UTILIZATION; GLYCOGENOLYSIS; GLYCOLYSIS; HEART CONTRACTION; HEART MUSCLE ISCHEMIA; HEART PROTECTION; ISOLATED HEART; MALE; METABOLIC RATE; NONHUMAN; PRIORITY JOURNAL; RAT; SYSTOLIC BLOOD PRESSURE;

EID: 0029793913     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.79.3.435     Document Type: Article

References (53)

1. Murry CE, Jennings RB, Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation. 1986;74:1124-1136.
2. Murry CE, Richard VJ, Reimer KA, Jennings RB. Ischemic preconditioning slows energy metabolism and delays ultrastructural damage during a sustained ischemic episode. Circ Res. 1990;66:913-931.
3. Wolfe CL, Sievers RE, Visseren FLJ, Donnelly TJ. Loss of myocardial protection after preconditioning correlates with the time course of glycogen recovery within the preconditioned segment. Circulation. 1993;87:881-892.
4. de Albuquerque CP, Gerstenblith G, Weiss RG. Importance of metabolic inhibition and cellular pH in mediating preconditioning contractile and metabolic effects in rat hearts. Circ Res. 1994;74:139-150.
5. Kida M, Fujiwara H, Ishida M, Kawai C, Ohura M, Miura I, Yabuuchi Y. Ischemic preconditioning preserves creatine phosphate and intracellular pH. Circulation. 1991;84:2495-2503.
6. Liu GS, Thornton J, Van Winkle DM, Stanley AWH, Olsson RA, Downey JM. Protection against infarction afforded by preconditioning is mediated by A1-adenosine receptors in rabbit heart. Circulation. 1991;84:350-356.
7. Steenbergen C, Perlman ME, London RE, Murphy E. Mechanism of preconditioning: ionic alterations. Circ Res. 1993;72:112-125.
8. Gross GJ, Auchampach JA. Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs. Circ Res. 1992;70:223-233.
9. Speechly-Dick ME, Mocanu MM, Yellon DM. Protein kinase C: its role in ischemic preconditioning in the rat. Circ Res. 1994;75:586-590.
10. Bankwala A, Hale SL, Kloner RA. α-Adrenoceptor stimulation with exogenous norepinephrine or release of endogenous catecholamines mimics ischemic preconditioning. Circulation. 1994;90:1023-1028.
11. Mitchell MB, Meng X, Ao L, Brown JM, Harken AH, Banerjee A. Preconditioning of isolated rat heart is mediated by protein kinase C. Circ Res. 1995:76:73-81.
12. 2+ homeostasis of cardiac myocytes. Circ Res. 1991;69:540-550.
13. 2+ exchange. Eur J Pharmacol. 1990;186:29-40.
14. Schaefer S, Carr LJ, Prussel E, Ramasamy R. Effects of glycogen depletion on ischemic injury in isolated rat hearts: insights into preconditioning. Am J Physiol. 1995;268:H935-H944.
15. de Albuquerque CP, Gerstenblith G, Weiss RG. Myocardial buffering capacity in ischemia preconditioned rat hearts. J Mol Cell Cardiol. 1995;27:777-781.
16. Opie LH. Substrate utilization and glycolysis in the heart. Cardiology. 1972;56:2-21.
17. Brainard JR, Hutson JY, Hoekenga DE, Lenhoff R. Ordered synthesis and mobilization of glycogen in the perfused heart. Biochemistry. 1989;28:9766-9772.
18. Laughlin MR, Petit WAJ, Dizon JM, Shulman RG, Barrett EJ. NMR measurements of in vivo myocardial glycogen metabolism. J Biol Chem. 1988;263:2285-2291.
19. Rovetto MJ, Lamberton WF, Neely JR. Mechanisms of glycolytic inhibition in ischemic rat hearts. Circ Res. 1975;37:742-751.
20. Peuhkurinen KJ, Takala TES, Nuutinen EM, Hassinen IE. Tricarboxylic acid cycle metabolites during ischemia in isolated perfused rat heart. Am J Physiol. 1983;244:H281-H288.
21. Kalil-Filho R. Gerstenblith G, Hansford RG. Chacko VP, Vandegaer KM, Weiss RG. Regulation of myocardial glycogenolysis during post-ischemic reperfusion. J Mol Cell Cardiol. 1991;23:1467-1479.
22. 13C NMR visibility of rabbit muscle glycogen in vivo. Magn Reson Med. 1991;20:327-332.
23. 13C NMR spectroscopy. NMR Biomed. 1993;6:84-88.
24. Weiss RG, Chacko VP, Gerstenblith G. Fatty acid regulation of glucose metabolism in the intact beating rat heart assessed by carbon-13 NMR spectroscopy: the critical role of pyruvate dehydrogenase. J Mol Cell Cardiol. 1989;21:469-478.
25. 31P NMR assessment of altered metabolism during graded reductions in coronary flow in intact rat hearts. Proc Natl Acad Sci U S A. 1989;86:6426-6430.
26. Weiss RG, Gloth ST, Kalil-Filho R, Chacko VP. Stern MD, Gerstenblith G. Indexing tricarboxylic acid cycle flux in intact hearts by carbon-13 nuclear magnetic resonance. Circ Res. 1992;70:392-408.
27. Weiss RG, Kalil-Filho R, Herskowitz A, Chacko VP, Litt M, Stern MD, Gerstenblith G. Tricarboxylic acid cycle activity in postischemic rat hearts. Circulation. 1993;87:270-282.
28. 13C NMR. Am J Physiol. 1993;2640:C755-C760.
29. Jacobus WE, Moreadith RW, Vandegaer KM. Mitochondrial respiratory control; evidence against the regulation of respiration by extramitochondrial phosphorylation potentials or by [ATP]/[ADP] ratios. J Biol Chem. 1982;257:2397-2402.
30. Walaas O, Walaas E. Effect of epinephrine on rat diaphragm. J Biol Chem. 1950;187:769-776.
31. Wexler LF, Lorell BH, Momomura S, Weinberg EO, Ingwall JS, Apstein CS. Enhanced sensitivity to hypoxia-induced diastolic dysfunction in pressure-overload left ventricular hypertrophy in the rat: role of high-energy phosphate depletion. Circ Res. 1988;62,4:766-775.
32. Zimmer SD, Ugurbil K, Michurski SP, Mohanakrishnan P, Ulstad VK, Foker JE, From AHL. Alterations in oxidative function and respiratory regulation in the post-ischemic myocardium. J Biol Chem. 1989;264:12402-12411.
33. Schjott J, Jynge P, Holten T, Brurok H. Ischaemic episodes of less than 5 minutes produce preconditioning but not stunning in the isolated rat heart. Acta Physiol Scand. 1994;150:281-291.
34. Asimakis GK, Inners-McBride K, Conti VR. Attenuation of postischaemic dysfunction by ischaemic preconditioning is not mediated by adenosine in the isolated rat heart. Cardiovasc Res. 1993;27:1522-1530.
35. Asimakis GK, Inners-McBride K, Medellin G, Conti VR. Ischemic preconditioning attenuates acidosis and postischemic dysfunction in isolated rat heart. Am J Physiol. 1992;263:H887-H894.
36. Neely JR, Morgan HE. Relationship between carbohydrate and lipid metabolism and the energy balance of heart muscle. Annu Rev Physiol. 1974;36:413-459.
37. Neely JR, Whitmer JT, Rovetto MJ. Effect of coronary blood flow on glycolytic flux and intracellular pH in isolated rat hearts. Circ Res. 1975;37:733-741.
38. Williamson JR. Glycolytic control mechanisms: inhibition of glycolysis by acetate and pyruvate in the isolated, perfused rat heart. J Biol Chem. 1965;240,6:2308-2321.
39. Morgan HE, Parmeggiani A. Regulation of glycogenolysis in muscle: control of glycogen phosphorylase reaction in isolated perfused heart. J Biol Chem. 1964;239:2435-2439.
40. Neely JR, Whitfield CF, Morgan HE. Regulation of glycogenolysis in hearts: effects of pressure development, glucose, and FFA. Am J Physiol. 1970;219:1083-1088.
41. Wollenberger A, Krause EG, Heier G. Stimulation of 3′, 5′-cyclic amp formation in dog myocardium following arrest of blood flow. Biochem Biophys Res Commun. 1969;36:664-670.
42. Sandhu R, Thomas U, Diaz RJ, Wilson GJ. Effect of ischemic preconditioning of the myocardium on cAMP. Circ Res. 1996;78:137-147.
43. Li Y, Whittaker P, Kloner RA. The transient nature of the effect of ischemic preconditioning on myocardial infarct size and ventricular arrhythmia. Am Heart J. 1992;123:346-353.
44. Bailey IA, Radda GK, Seymour AL, Williams SR. The effects of insulin on myocardial metabolism and acidosis in normoxia and ischaemia. Biochim Biophys Acta. 1982;720:17-27.
45. Sun D, Nguyen N, Degrade TR, Schwaiger M, Brosius FC III. Ischemia induces translocation of the insulin-responsive glucose transporter GLUT4 to the plasma membrane of cardiac myocytes. Circulation. 1994;89:793-798.
46. Janier MF, Vanoverschelde JJ, Bergmann SR. Ischemic preconditioning stimulates anaerobic glycolysis in the isolated rabbit heart. Am J Physiol. 1994;267:H1353-H1360.
47. Henning SL, Wambolt RB, Schonekess BO, Lopaschuk GD, Allard MF. Contribution of glycogen to aerobic myocardial glucose utilization. Circulation. 1996;93:1549-1555.
48. Goodwin GW, Arteaga JR, Taegtmeyer H. Glycogen turnover in the isolated working rat heart. J Biol Chem. 1995;270:9234-9240.
49. Alonso MD, Lomako J, Lomako WM, Whelan WJ. A new look at the biogenesis of glycogen. FASEB J. 1995;9:1126-1137.
50. Dennis SC, Gevers W, Opie LH. Protons in ischemia: where do they come from; where do they go? J Mol Cell Cardiol. 1991;23:1077-1086.
51. Neely JR, Grotyohann LW. Role of glycolytic products in damage to ischemic myocardium: dissociation of adenosine triphosphate levels and recovery of function of reperfused ischemic hearts. Circ Res. 1984;55:816-824.
52. Lagerstrom CF, Walker WE, Taegtmeyer H. Failure of glycogen depletion to improve left ventricular function of the rabbit heart after hypothermic ischemic arrest. Circ Res. 1988;63:81-86.
53. Cross HR, Opie LH, Radda GK, Clarke K. Is a high glycogen content beneficial or detrimental to the ischemic rat heart?: a controversy resolved. Circ Res. 1996;78:482-491.