Selectivity of diadenosine polyphosphates for rat P2X receptor subunits

European Journal of Pharmacology

Volumn 367, Issue 1, 1999, Pages 119-123

  Wildman, Scott S ^a,b   Brown, Sean G ^a,b   King, Brian F ^a,b   Burnstock, Geoffrey ^a,b  

^a ROYAL FREE HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Adenine dinucleotide; ATP; Diadenosine polyphosphate; P2X receptor; Xenopus oocyte

Indexed keywords

ADENOSINE TRIPHOSPHATE; DIADENOSINE HEXAPHOSPHATE; DIADENOSINE PENTAPHOSPHATE; DIADENOSINE POLYPHOSPHATE; PARTIAL AGONIST; PURINE P2X RECEPTOR; RECOMBINANT RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SELECTIVITY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RAT; VOLTAGE CLAMP; XENOPUS;

ADENINE NUCLEOTIDES; ADENOSINE TRIPHOSPHATE; ANIMALS; BINDING, COMPETITIVE; DINUCLEOSIDE PHOSPHATES; DOSE-RESPONSE RELATIONSHIP, DRUG; MEMBRANE POTENTIALS; OOCYTES; RATS; RECEPTORS, PURINERGIC P2; RNA, MESSENGER; XENOPUS;

EID: 0032966623     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00976-5     Document Type: Article

References (26)

1. Abbracchio M.P., Burnstock G. Purinoceptors: are there families of P2X and P2Y purinoceptors? Pharmacol. Ther. 64:1994;445-475.
2. Bo X., Zhang Y., Nassar M., Burnstock G., Schoepfer R. A P2X purinoceptor cDNA conferring a novel pharmacological profile. FEBS Lett. 375:1995;129-133.
3. Chen C.C., Akopian A.N., Sivilotti L., Colquhoun D., Burnstock G., Wood J.N. A P2X purinoceptor expressed by a subset of sensory neurons. Nature. 377:1995;428-431.
4. 6 receptors and the distribution and properties of an extended family of ATP-gated ion channels. J. Neurosci. 16:1996;2495-2507.
5. Evans R.J., Surprenant A. P2X receptors in autonomic and sensory ganglia. Semin. Neurosci. 8:1996;217-223.
6. Evans R.J., Lewis C., Buell G., Valera S., North R.A., Surprenant A. Pharmacological characterization of heterologously expressed ATP-gated cation channels (P2X purinoceptors). Mol. Pharmacol. 48:1995;178-183.
7. Hoyle C.H.V. Pharmacological activity of adenine dinucleotides in the periphery: possible receptor classes and transmitter function. Gen. Pharmacol. 21:1990;827-831.
8. Jimenez A.I., Castro E., Delicado E.G., Miras-Portugal M.T. Potentiation of adenosine 5′-triphosphate calcium responses by diadenosine pentaphosphate in individual rat cerebellar astrocytes. Neurosci. Lett. 246:1998;109-111.
9. King, B.F., 1998. Molecular biology of P2X purinoceptors. In: Burnstock, G., Dobson, J.G., Laing, B.T., Linden, J. (Eds.), Cardiovascular Biology of Purines, Chap. 10. Kluwer Academic, Boston, pp. 159-186.
10. 2 purinoceptor to ATP revealed by changing extracellular pH. Br. J. Pharmacol. 117:1996;1371-1373.
11. 2 receptor. Br. J. Pharmacol. 121:1997;1445-1453.
12. Krishtal O.A., Marchenko S.M., Obukhov A.G., Volkova T.M. Receptors for ATP in rat sensory neurones: the structure-function relationship for ligands. Br. J. Pharmacol. 95:1988;1057-1062.
13. Lê K.T., Villeneuve P., Ramjaun A.R., McPherson P.S., Beaudet A., Séguéla P. Sensory presynaptic and widespread somatodendritic immunolocalization of central ionotropic P2X ATP receptors. Neuroscience. 83:1998;177-190.
14. 3 receptor subunits can account for ATP-gated currents in sensory neurones. Nature. 377:1995;432-435.
15. 4 receptors in rat vascular smooth muscle: an in situ hybridization and RT-PCR study. J. Vasc. Res. 35:1998;179-185.
16. North R.A., Barnard E.A. Nucleotide receptors. Curr. Opin. Neurobiol. 7:1997;346-357.
17. Ogilvie A., Blasius R., Schulze-Lohoff E., Sterzel R.B. Adenine dinucleotides: a novel class of signalling molecules. J. Auton. Pharmacol. 16:1996;325-328.
18. 2 purinergic receptors for diadenosine polyphosphates in the nervous system. Gen. Pharmacol. 26:1995;229-235.
19. 1 purinoceptors. Br. J. Pharmacol. 119:1996;1006-1012.
20. Pintor J., Hoyle C.H.V., Gualix J., Miras-Portugal M.T. Diadenosine polyphosphates in the central nervous system. Neurosci. Res. Commun. 20:1997;69-78.
21. 3-receptors present in neurones of the rat dorsal root ganglia. Br. J. Pharmacol. 124:1998;176-180.
22. Robertson S.J., Rae M.G., Rowan E.G., Kennedy C. Characterization of a P2X-purinoceptor in cultured neurones of the rat dorsal root ganglia. Br. J. Pharmacol. 118:1996;951-956.
23. Stoop R., Surprenant A., North R.A. Different sensitivities to pH of ATP-induced currents at four cloned P2X receptors. J. Neurophysiol. 78:1997;1837-1840.
24. Valera S., Hussy N., Evans R.J., Adami N., North R.A., Surprenant A., Buell G. A new class of ligand-gated ion channel defined by P2X receptor for extracellular ATP. Nature. 371:1995;516-519.
25. Vulchanova L., Arvidsson U., Riedl M., Wang J., Buell G., Surprenant A., North R.A., Elde R. Differential distribution of two ATP-gated ion channels (P2X receptors) determined by immunohistochemistry. Proc. Natl. Acad. Sci. USA. 93:1996;8063-8067.
26. 2 receptors and its dependence on pH. Br. J. Pharmacol. 123:1998;1214-1220.