Gene therapy for myocardial angiogenesis

American Heart Journal

Volumn 138, Issue 2 II, 1999, Pages

  Losordo, D W ^a   Vale, P R ^a   Isner, J M ^a  

^a ST ELIZABETH'S MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT VASCULOTROPIN;

ADULT; AGED; ANGIOGENESIS; CLINICAL ARTICLE; CLINICAL TRIAL; COLLATERAL CIRCULATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DNA DETERMINATION; GENE TARGETING; GENE THERAPY; GENE TRANSFER; HEART MUSCLE CELL; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; NONHUMAN; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; RAT; REVIEW; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SWINE;

EID: 0032770333     PISSN: 00028703     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-8703(99)70333-9     Document Type: Article

References (41)

1. Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971;285:1182-6.
2. Shing Y, Folkman J, Sullivan J, et al. Heparin-affinity purification of a tumor-derived capillary endothelial cell growth factor. Science 1984;223:1296-9.
3. White FC, Carroll SM, Magnet A, et al. Coronary collateral development in swine after coronary artery occlusion. Circ Res 1992;71:1490-500.
4. Baffour R, Berman J, Garb JL, et al. Enhanced angiogenesis and growths of collaterals by in vivo administration of recombinant basic fibroblast growth factor in a rabbit model of acute lower limb ischemia: dose-response effect of basic fibroblast growth factor. J Vasc Surg 1992;16:181-91.
5. Pu LQ, Sniderman AD, Brassard R, et al. Enhanced revascularization of the ischemic limb by means of angiogenic therapy. Circulation 1993;88:208-15.
6. Yanagisawa-Miwa A, Uchida Y, Nakamura F, et al. Salvage of infarcted myocardium by angiogenic action of basic fibroblast growth factor. Science 1992;257:1401-3.
7. Ferrara N, Henzel WJ. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun 1989;161:851-5.
8. Keck PJ, Hauser SD, Krivi G, et al. Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science 1989;246:1309-12.
9. Connolly DR, Olander JV, Heuvelman D, et al. Human vascular permeability factor: isolation from U937 cells. J Biol Chem 1989;264:20017-24.
10. Leung DW, Cachianes G, Kuang WJ, et al. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 1989;246:1306-9.
11. deVries C, Escobedo JA, Ueno H, et al. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 1992;255:989-91.
12. Millauer B, Wizigmann-Voos S, Schnurch H, et al. High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 1993;72:835-46.
13. Terman BI, Dougher-Vermazen M, Carrion ME, et al. Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem Biophys Res Commun 1992;187:1579-86.
14. Klagsbrun M, D'Amore PA. Regulators of angiogenesis. Annu Rev Physiol 1991;53:217-39.
15. Gospodarowicz D, Massoglia S, Cheng J, et al. Effect of fibroblast growth factor and lipoproteins on the proliferation of endothelial cells derived from bovine adrenal cortex, brain cortex, and corpus luteum capillaries. J Cell Physiol 1986;127:121-36.
16. Conn G, Soderman D, Schaeffer M-T, et al. Purification of glycoprotein vascular endothelial cell mitogen from a rat glioma cell line. Proc Natl Acad Sci U S A 1990;87:1323-7.
17. Shen H, Clauss M, Ryan J, et al. Characterization of vascular permeability factor/vascular endothelial growth factor receptors on mononuclear phagocytes. Blood 1993;81:2767-73.
18. Clauss M, Gerlach M, Gerlach H, et al. Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration. J Exp Med 1990;172:1535-45.
19. Levy AP, Tamargo R, Brem H, et al. An endothelial cell growth factor from the mouse neuroblastoma cell line NB41. Growth Factors 1989;2:9-19.
20. Connolly DT, Hewelman DM, Nelson R, et al. Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J Clin Invest 1989;84:1470-8.
21. Takeshita S, Zheng LP, Brogi E, et al. Therapeutic angiogenesis: a single intra-arterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model. J Clin Invest 1994;93:662-70.
22. Takeshita S, Pu L-Q, Zheng L, et al. Vascular endothelial growth factor induces dose-dependent revascularization in a rabbit model of persistent limb ischemia. Circulation 1994;90:II-228-34.
23. Isner JM, Kaufman J, Rosenfield K, et al. Combined physiologic and anatomic assessment of percutaneous revascularization using a Doppler guidewire and ultrasound catheter. Am J Cardiol 1993;71:70D-86D.
24. Bauters C, Asahara T, Zheng LP, et al. Physiologic assessment of augmented vascularity induced by VEGF in ischemic rabbit hindlimb. Am J Physiol 1994;267:H1263-71.
25. Losordo DW, Pickering JG, Takeshita S, et al. Use of the rabbit ear artery to serially assess foreign protein secretion after site specific arterial gene transfer in vivo: evidence that anatomic identification of successful gene transfer may underestimate the potential magnitude of transgene expression. Circulation 1994;89:785-92.
26. Riessen R, Rahimizadeh H, Blessing E, et al. Arterial gene transfer using pure DNA applied directly to a hydrogel-coated angioplasty balloon. Hum Gene Ther 1993;4:749-58.
27. 165. Lancet 1996;348:370-4.
28. Nabel EG, Plautz G, Nabel GJ. Transduction of a foreign histocompatibility gene into the arterial wall induces vasculitis. Proc Natl Acad Sci U S A 1992;89:5157-61.
29. Nabel EG, Yang Z, Liptay S, et al. Recombinant platelet-derived growth factor B gene expression in porcine arteries induces intimal hyperplasia in vivo. J Clin Invest 1993;91:1822-9.
30. Nabel EG, Yang ZY, Plautz G, et al. Recombinant fibroblast growth factor-1 promotes intimal hyperplasia and angiogenesis in arteries in vivo. Nature 1993;362:844-6.
31. Takeshita S, Losordo DW, Kearney M, et al. Time course of recombinant protein secretion following liposome-mediated gene transfer in a rabbit arterial organ culture model. Lab Invest 1994;71:387-91.
32. Tsurumi Y, Takeshita S, Chen D, et al. Direct intramuscular gene transfer of naked DNA encoding vascular endothelial growth factor augments collateral development and tissue perfusion. Circulation 1996;94:3281-90.
33. Takeshita S, Isshiki T, Sato T. Increased expression of direct gene transfer into skeletal muscles observed after acute ischemic injury in rats. Lab Invest 1996;74:1061-5.
34. Losordo DW, et al. Gene therapy for myocardial angiogenesis. Circulation 1998;98:2800-4.
35. Hariawala MD, et al. VEGF improves myocardial blood flow but produces EDRF-mediated hypotension in porcine hearts. J Surg Res 1996;63:77-82.
36. Gal D, Weir L, Leclerc G, et al. Direct myocardial transfection in two animal models: evaluation of parameters affecting gene expression and percutaneous gene delivery. Lab Invest 1993;68:18-25.
37. Oswald H, Heinemann F, Nikol S, et al. Removal of an inhibitor of marker enzyme activity in artery extracts by chelating agents. Biotechniques 1997;22:78-81.
38. Tsurumi Y, Murohara T, Krasinski K, et al. Reciprocal relationship between VEGF and NO in the regulation of endothelial integrity. Nat Med 1997;3:879-86.
39. Tischer E, Mitchell R, Hartmann T, et al. The human gene for vascular endothelial growth factor: multiple protein forms are encoded through alternative exon splicing. J Biol Chem 1991;266:11947-54.
40. 165 following intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia. Circulation 1998;97:1114-23.
41. Rentrop KP, Cohen M, Blanke H, et al. Changes in coronary collateral filling immediately after controlled coronary artery occlusion by an angioplasty balloon in human subjects. J Am Coll Cardiol 1985;5:587-92.