Gene expression of activin, activin receptors, and follistatin in intestinal epithelial cells

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 278, Issue 1 41-1, 2000, Pages

  Sonoyama, Kei ^a   Rutatip, Suriya ^a   Kasai, Takanori ^a   Sonoyama, K ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Caco 2; Crypt villus axis; Differentiation; IEC 6; RT PCR

Indexed keywords

ACTIVIN; ACTIVIN A; ACTIVIN RECEPTOR; APOLIPOPROTEIN A4; FOLLISTATIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL ISOLATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; EPITHELIUM CELL; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INTESTINE EPITHELIUM; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS;

EID: 0033955251     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.2000.278.1.g89     Document Type: Article

References (37)

1. Barnard, J. A., R. D. Beauchamp, R. J. Coffey, and H. I. Moses. Regulation of intestinal epithelial cell growth by transforming growth factor type β. Proc. Natl. Acad. Sci. USA. 86: 1578-1582, 1989.
2. Barnard, J. A., W. H. Polk, H. L. Moses, and R. J. Coffey. Production of transforming growth factor-α by normal rat small intestine. Am. J. Physiol. Cell Physiol. 261: C994-C1000, 1991.
3. Cheng, H., and C. P. Leblond. Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian theory of the origin of the four epithelial cell types. Am. J. Anat. 141: 537-562, 1974.
4. Dembinski, A., H. Gregory, S. J. Konturek, and M. Polanski. Trophic action of epidermal growth factor on the pancreas and gastroduodenal mucosa in rats. J. Physiol. (Lond.) 325: 35-42, 1982.
5. WAF1/CIP1 expression in normal and neoplastic tissues. Cancer Res. 55: 2910-2919, 1995.
6. Evers, B. M., T. C. Ko, J. Li, and E. A. Thompson. Cell cycle protein suppression and p21 induction in differentiating Caco-2 cells. Am. J. Physiol. Gastrointest. Liver Physiol. 271: G722-G727, 1996.
7. Fang, J. M., W. S. Yin, E. Smiley, S. Q. Wang, and J. Bonadio. Molecular cloning of the mouse activin β (e) subunit gene. Biochem. Biophys. Res. Commun. 228: 669-674, 1996.
8. Gartel. A. L., M. S. Serfas, M. Gartel, E. Goufman, G. S. Wu, W. S. El-Deiry, and A. L. Tyner. p21(WAF1/CIP1) expression is induced in newly nondividing cells in diverse epithelia and during differentiation of the Caco-2 intestinal cell line. Exp. Cell Res. 227: 171-181, 1996.
9. Hall, P. A., P. J. Coates, B. Ansari, and D. Hopwood. Regulation of cell number in the mammalian gastrointestinal tract: the importance of apoptosis. J. Cell. Sci. 107: 3569-3577, 1994.
10. Hauri, H. P., E. E. Sterchi, D. Bienz, J. A. M. Fransen, and A. Marxer. Expression and intracellular transport of microvillus membrane hydrolases in human intestinal epithelial cells. J. Cell. Biol. 101: 838-851, 1985.
11. Hermiston, M. L., T. C. Simon, M. W. Grossman, and J. I. Gordon. Model systems for studying cell fate specification and differentiation in the gut epithelium. In: Physiology of the Gastrointestinal Tract, 3rd ed, edited by L. R. Johnson. New York: Raven, 1994, chapt. 12, p. 521-569.
12. Hidalgo, I. J., T. J. Raub, and R. T. Borchardt. Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal cell permeability. Gastroenterology 96: 736-749, 1989.
13. Hotten, G., H. Neidhardt, C. Schneider, and J. Pohl. Cloning of a new member of the TGF-β family: a putative new activin βC chain. Biochem. Biophys. Res. Commun. 106: 608-613, 1995.
14. Hubner, G., M. Brauchle, M. Gregor, and S. Werner. Activin A: a novel player and inflammatory marker in inflammatory bowel disease? Lab. Invest. 77: 311-318, 1997.
15. Kawamura, N., R. Nobusawa, H. Mashima, M. Kanzaki, H. Shibata, and I. Kojima. Production of activin A in human intestinal epithelial cell line. Dig. Dis. Sci. 40: 2280-2285, 1995.
16. Kingsley, D. M. The TGF-β superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev. 8: 133-146, 1994.
17. Kurokowa, M., K. Lynch, and D. K. Podolsky. Effects of growth factors on an intestinal epithelial cell line: transforming growth factor β inhibits proliferation and stimulates differentiation. Biochem. Biophys. Res. Commun. 142: 775-782, 1987.
18. Ling, N., S. A. Ying, N. Ueno, S. Shimasaki, F. Esch, M. Hotta, and R. Guillemin. Pituitary FSH is released by a heterodimer of the β-subunits from the two forms of inhibin. Nature 321: 779-782, 1986.
19. Lowry, O. H., H. J. Rosebrough, A. L. Farr, and R. J. Randall. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265-275, 1951.
20. Massagué, J. The transforming growth factor-β family. Annu. Rev. Cell Biochem. 6: 597-641, 1990.
21. Mathews, L. S., and W. W. Vale. Molecular and functional characterization of activin receptors. Receptor 3: 173-181, 1993.
22. Michel, U., P. Farnworth, and J. K. Findlay. Follistatins: more than follicle-stimulating hormone suppressing proteins. Mol. Cell. Endocrinol. 91: 1-11, 1993.
23. Moustakas, A., and D. Kardassis. Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members. Proc. Natl. Acad. Sci. USA. 95: 6733-6738, 1998.
24. Oda, S., S.-I. Nishimatsu, K. Murakami, and N. Ueno. Molecular cloning and functional analysis of a new activin β subunit: a dorsal mesoderm-inducing activity in Xenopus. Biochem. Biophys. Res. Commun. 210: 581-588, 1995.
25. Parker, S. B., G. Eichele, P. Zhang, A. Rawls, A. T. Sands, A. Bradley, E. N. Olson, J. W. Harper, and S. J. Elledge. p53-independent expression of p21 Cip1 in muscle and other terminally differentiating cells. Science 267: 1024-1027, 1995.
26. Pinto, M., S. Robine-Leon, M. D. Appay, M. Kedinger, N. Triadou, E. Dussaulx, B. Lacroix, P. Simon-Assmann, K. Haffen, J. Fogh, and A. Sweilbaum. Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture. Biol. Cell. 47: 323-330, 1983.
27. Sakai, R., K. Miwa, and Y. Eto. Local administration of activin promotes fracture healing in the rat fibula fracture model. Bone 25: 191-196, 1999.
28. Seidel, E. R., M. K. Haddox, and L. R. Johnson. Ileal mucosal growth during intraluminal infusion of ethylamine or putrescine. Am. J. Physiol. Gastrointest. Liver Physiol. 249: G434-G438, 1985.
29. Sonoyama, K., Y. Nakamura, S. Kiriyama, and R. Niki. Upregulation of apolipoprotein A-IV gene expression in residual ileum after massive small bowel resection requires the biliary secretion in rats. Proc. Soc. Exp. Biol. Med. 211: 273-280, 1996.
30. Sonoyama, K., H. Nishikawa, S. Kiriyama, and R. Niki. Apolipoprotein mRNA in liver and intestine of rats is affected by dietary beet fiber or cholestyramine. J. Nutr. 125: 343-352, 1995.
31. Traber, P. G., D. L. Gumucio, and W. Wang. Isolation of intestinal epithelial cells for the study of differential gene expression along the crypt-villus axis. Am. J. Physiol. Gastrointest. Liver Physiol. 260: G895-G903, 1991.
32. Vachon, P. H., and J.-F. Beaulieu. Transient mosaic patterns of morphological and functional differentiation in the Caco-2 cell line. Gastroenterology 103: 414-423, 1992.
33. Vale, W., J. Rivier, J. Vaughan, R. McClintock, A. Corrigan, W. Woo, D. Karr, and J. Spiess. Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid. Nature 321: 776-779, 1986.
34. Wagner, R. D., E. S. Krul, J. B. Moberly, D. H. Alpers, and G. Schonfeld. Apolipoprotein expression and cellular differentiation in Caco-2 intestinal cells. Am. J. Physiol. Endocrinol. Metab. 263: E374-E382, 1992.
35. Walter, K., and C. Schutt. Alkaline phosphatase in serum (continuous assay). In: Methods of Enzymatic Analysis, 2nd ed., edited by H. U. Bergmeyer. New York: Verlag Chemie, Weinheim/ Academic, 1974, p. 860-864.
36. Weiser, M. M. Intestinal epithelial cell surface membrane glycoprotein synthesis. I. An indicator of cellular differentiation. J. Biol. Chem. 248: 2536-2541, 1973.
37. WAF1/Cip1, CDK4 and Rb in activin A-mediated signaling leading to hepatoma cell growth inhibition. Oncogene 15: 1705-1711, 1997.