Blockade of the P38 mitogen-activated protein kinase pathway inhibits inducible nitric oxide synthase and interleukin-6 expression in MC3T3E-1 osteoblasts

Pharmacological Research

Volumn 43, Issue 3, 2001, Pages 275-282

  Chae, Han Jung ^a,c   Kim, Sang Chul ^b   Chae, Soo Wan ^c   An, Nyeon Hyoung ^b   Kim, Hong Hee ^d   Lee, Zang Hee ^d   Kim, Hyung Ryong ^a  

^a Wonkwang University School of Medicine   (South Korea)

^b Wonkwang University   (South Korea)

^c Chonbuk National University   (South Korea)

^d Chosun University   (South Korea)

Author keywords

Inducible nitric oxide synthase; Interferon ; Interleukin 6; Lipopolysaccharide; p38 MAPK; Tumor necrosis factor

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; GAMMA INTERFERON; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NITRIC OXIDE SYNTHASE; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; GENETIC TRANSCRIPTION; NONHUMAN; NORTHERN BLOTTING; OSTEOBLAST; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0034956520     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1006/phrs.2000.0778     Document Type: Article

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