메뉴 건너뛰기




Volumn 117, Issue 1, 2001, Pages 132-140

Interleukin-6-resistant melanoma cells exhibit reduced activation of STAT3 and lack of inhibition of cyclin E-associated kinase activity

Author keywords

Cell cycle; Interleukin 6; Melanoma; Signal transducer and activator of transcription 3; Signal transduction

Indexed keywords

CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE 2; CYCLIN E; DNA; HISTONE H1; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOTRANSFERASE; PROTEIN P21; PROTEIN P27; RETINOBLASTOMA PROTEIN; STAT3 PROTEIN;

EID: 0034947391     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0022-202X.2001.01372.x     Document Type: Article
Times cited : (17)

References (57)
  • 21
    • 0029887373 scopus 로고    scopus 로고
    • Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. I. Definition of a novel phosphotyrosine motif mediating STAT1 activation
    • (1996) J Biol Chem , vol.271 , pp. 12991-12998
    • Gerhartz, C.1    Heesel, B.2    Sasse, J.3    Hemmann, U.4    Landgraf, C.5
  • 22
    • 0028922433 scopus 로고
    • A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6
    • (1995) EMBO J , vol.14 , pp. 1421-1429
    • Guschin, D.1    Rogers, N.2    Briscoe, J.3
  • 31
    • 0026731462 scopus 로고
    • Expression of multi-cytokine resistance and multi-growth Factor independence in advanced stage metastatic cancer. Malignant melanoma as a paradigm
    • (1992) Am J Pathol , vol.141 , pp. 519-524
    • Kerbel, R.S.1
  • 32
    • 0033600160 scopus 로고    scopus 로고
    • Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1
    • (1999) Oncogene , vol.1825 , pp. 3742-3753
    • Kortylewski, M.1    Heinrich, P.C.2    Mackiewicz, A.3
  • 33
    • 0027396955 scopus 로고
    • Interleukin-6 undergoes transition from paracrine growth inhibitor to autocrine stimulator during human melanoma progression
    • (1993) J Cell Biol , vol.120 , pp. 1281-1287
    • Lu, C.1    Kerbel, R.S.2
  • 40
    • 0023052239 scopus 로고
    • An Hsp 70-like protein in the ER identity with the 78 kD glucose-regulated and immunoglobulin heavy chain binding protein
    • (1986) Cell , vol.46 , pp. 291-300
    • Munro, S.1    Pelham, H.R.B.2
  • 52
    • 0025282543 scopus 로고
    • Identification by anti-idiotype antibodies of an intracellular membrane protein that recognizes a mammalian endoplasmic reticulum retention signal
    • (1990) Nature , vol.345 , pp. 495-502
    • Vaux, D.1    Tooze, J.2    Fuller, S.3
  • 54
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 55
    • 0030744123 scopus 로고    scopus 로고
    • Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3
    • (1997) Nucleic Acids Res , vol.25 , pp. 2062-2067
    • Wen, Z.1    Darnell J.E., Jr.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.