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Volumn 114, Issue 6, 2000, Pages 1200-1204

Expression of activated N-ras in a primary melanoma cell line counteracts growth inhibition by transforming growth factor-β

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; LUCIFERASE; RETINOBLASTOMA PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 0034044890     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2000.00988.x     Document Type: Article
Times cited : (20)

References (39)
  • 1
    • 0024438925 scopus 로고
    • Analysis of ras oncogenes in malignant melanoma and precursor lesions: Correlation of point mutations with differentiation phenotype
    • Albino AP, Nanus DM, Mentle IR, Cordon-Cardo C, McNutt NS, Bressler J, Andreeff M: Analysis of ras oncogenes in malignant melanoma and precursor lesions: correlation of point mutations with differentiation phenotype. Ontogene 4:1363-1374, 1989
    • (1989) Ontogene , vol.4 , pp. 1363-1374
    • Albino, A.P.1    Nanus, D.M.2    Mentle, I.R.3    Cordon-Cardo, C.4    McNutt, N.S.5    Bressler, J.6    Andreeff, M.7
  • 2
    • 0028953810 scopus 로고
    • Transforming growth factor beta and cell cycle regulation
    • Alexandrow MG, Moses HL: Transforming growth factor beta and cell cycle regulation. Cancer Res 55:1452-1457, 1995
    • (1995) Cancer Res , vol.55 , pp. 1452-1457
    • Alexandrow, M.G.1    Moses, H.L.2
  • 3
    • 0027525105 scopus 로고
    • Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors
    • Attisano L, Carcamo J, Ventura F, Weis FM, Massague J, Wrana JL: Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors. Cell 75:671-680, 1993
    • (1993) Cell , vol.75 , pp. 671-680
    • Attisano, L.1    Carcamo, J.2    Ventura, F.3    Weis, F.M.4    Massague, J.5    Wrana, J.L.6
  • 5
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: A review
    • Bos JL: Ras oncogenes in human cancer: a review. Cancer Res 49:4682-4689, 1989
    • (1989) Cancer Res , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 6
    • 0024439444 scopus 로고
    • The retinoblastoma protein is phosphorylated during specific phases of the cell cycle
    • Buchkovich K, Duffy LA, Harlow E: The retinoblastoma protein is phosphorylated during specific phases of the cell cycle. Cell 58:1097-1105, 1989
    • (1989) Cell , vol.58 , pp. 1097-1105
    • Buchkovich, K.1    Duffy, L.A.2    Harlow, E.3
  • 7
    • 0024429019 scopus 로고
    • Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation
    • Chen PL, Scully P, Shew JY, Wang JY, Lee WH: Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation. Cell 58:1193-1198, 1989
    • (1989) Cell , vol.58 , pp. 1193-1198
    • Chen, P.L.1    Scully, P.2    Shew, J.Y.3    Wang, J.Y.4    Lee, W.H.5
  • 8
    • 0030729474 scopus 로고    scopus 로고
    • Cooperative effects of INK4a and ras in melanoma susceptibility in vivo
    • Chin L, Pomerantz J, Polsky D, et al: Cooperative effects of INK4a and ras in melanoma susceptibility in vivo. Genes Dev 11:2822-2834, 1997
    • (1997) Genes Dev , vol.11 , pp. 2822-2834
    • Chin, L.1    Pomerantz, J.2    Polsky, D.3
  • 9
    • 0033614962 scopus 로고    scopus 로고
    • Essential role for oncogenic Ras in tumour maintenance
    • Chin L, Tam A, Pomerantz J, et al: Essential role for oncogenic Ras in tumour maintenance. Nature 400:468-472, 1999
    • (1999) Nature , vol.400 , pp. 468-472
    • Chin, L.1    Tam, A.2    Pomerantz, J.3
  • 11
    • 0024418207 scopus 로고
    • The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element
    • DeCaprio JA, Ludlow JW, Lynch D, et al: The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. Cell 58:1085-1095, 1989
    • (1989) Cell , vol.58 , pp. 1085-1095
    • DeCaprio, J.A.1    Ludlow, J.W.2    Lynch, D.3
  • 12
    • 0029781017 scopus 로고    scopus 로고
    • Relevance of ultraviolet-induced N-ras oncogene point mutations in development of primary human cutaneous melanoma
    • van Elsas A, Zerp SF, van der Flier S, et al: Relevance of ultraviolet-induced N-ras oncogene point mutations in development of primary human cutaneous melanoma. Am J Pathol 149:883-893, 1996
    • (1996) Am J Pathol , vol.149 , pp. 883-893
    • Van Elsas, A.1    Zerp, S.F.2    Van Der Flier, S.3
  • 13
    • 0026538833 scopus 로고
    • Overexpression of H-ras oncogene induces resistance to the growth-inhibitory action of transforming growth factor beta-1 (TGF-beta 1) and alters the number and type of TGF-beta 1 receptors in rat intestinal epithelial cell clones
    • Filmus J, Zhao J, Buick RN: Overexpression of H-ras oncogene induces resistance to the growth-inhibitory action of transforming growth factor beta-1 (TGF-beta 1) and alters the number and type of TGF-beta 1 receptors in rat intestinal epithelial cell clones. Oncogene 7:521-526, 1992
    • (1992) Oncogene , vol.7 , pp. 521-526
    • Filmus, J.1    Zhao, J.2    Buick, R.N.3
  • 14
    • 0030457645 scopus 로고    scopus 로고
    • TGF-beta mediated G1 arrest in a human melanoma cell line lacking p15INK4B: Evidence for cooperation between p21Cip1/WAF1 and p27Kip1
    • Florenes VA, Bhattacharya N, Bani MR, Ben-David Y, Kerbel RS, Slingerland JM: TGF-beta mediated G1 arrest in a human melanoma cell line lacking p15INK4B: evidence for cooperation between p21Cip1/WAF1 and p27Kip1. Oncogene 13:2447-2457, 1996
    • (1996) Oncogene , vol.13 , pp. 2447-2457
    • Florenes, V.A.1    Bhattacharya, N.2    Bani, M.R.3    Ben-David, Y.4    Kerbel, R.S.5    Slingerland, J.M.6
  • 15
    • 0032847433 scopus 로고    scopus 로고
    • Overexpression of mutant ras in human melanoma increases invasiveness, proliferation and anchorage-independent growth in vitro and induces tumour formation and cachexia in vivo
    • Fujita M, Norris DA, Yagi H, et al: Overexpression of mutant ras in human melanoma increases invasiveness, proliferation and anchorage-independent growth in vitro and induces tumour formation and cachexia in vivo. Melanoma Res 9:279-291, 1999
    • (1999) Melanoma Res , vol.9 , pp. 279-291
    • Fujita, M.1    Norris, D.A.2    Yagi, H.3
  • 16
    • 0027421280 scopus 로고
    • Resistance to inhibition of cell growth by transforming growth factor-beta and its role in oncogenesis
    • Fynan TM, Reiss M: Resistance to inhibition of cell growth by transforming growth factor-beta and its role in oncogenesis. Crit Rev Oncol 4:493-540, 1993
    • (1993) Crit Rev Oncol , vol.4 , pp. 493-540
    • Fynan, T.M.1    Reiss, M.2
  • 18
    • 0028168242 scopus 로고
    • p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest
    • Hannon GJ, Beach D: p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest. Nature 371:257-261, 1994
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 19
    • 0022393181 scopus 로고
    • Characteristics of cultured human melanocytes isolated from different stages of tumor progression
    • Herlyn M, Thurin J, Balaban G, et al. Characteristics of cultured human melanocytes isolated from different stages of tumor progression. Cancer Res 45:5670-5676, 1985
    • (1985) Cancer Res , vol.45 , pp. 5670-5676
    • Herlyn, M.1    Thurin, J.2    Balaban, G.3
  • 21
    • 0026802989 scopus 로고
    • Regulation of retinoblastoma protein functions by ectopic expression of human cyclins
    • Hinds PW, Mittnacht S, Dulic V, Arnold A, Reed SI, Weinberg RA: Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell 70:993-1006, 1992
    • (1992) Cell , vol.70 , pp. 993-1006
    • Hinds, P.W.1    Mittnacht, S.2    Dulic, V.3    Arnold, A.4    Reed, S.I.5    Weinberg, R.A.6
  • 22
    • 0024582143 scopus 로고
    • Introduction of a Ha-ras oncogene into rat liver epithelial cells and parenchymal hepatocytes confers resistance to the growth inhibitory effects of TGF-beta
    • Houck KA, Michalopoulos GK, Strom SC: Introduction of a Ha-ras oncogene into rat liver epithelial cells and parenchymal hepatocytes confers resistance to the growth inhibitory effects of TGF-beta. Oncogene 4:19-25, 1989
    • (1989) Oncogene , vol.4 , pp. 19-25
    • Houck, K.A.1    Michalopoulos, G.K.2    Strom, S.C.3
  • 23
    • 0027340547 scopus 로고
    • Release from G1 growth arrest by transforming growth factor beta 1 requires cellular ras activity
    • Howe PH, Dobrowolski SF, Reddy KB, Stacey DW: Release from G1 growth arrest by transforming growth factor beta 1 requires cellular ras activity. J Biol Chem 268:21448-21452, 1993
    • (1993) J Biol Chem , vol.268 , pp. 21448-21452
    • Howe, P.H.1    Dobrowolski, S.F.2    Reddy, K.B.3    Stacey, D.W.4
  • 24
    • 0028891865 scopus 로고
    • Analysis of ras mutations in human melanocytic lesions: Activation of the ras gene seems to be associated with the nodular type of human malignant melanoma
    • Jafari M, Papp T, Kirchner S, Diener U, Henschler D, Burg G, Schiffmann D: Analysis of ras mutations in human melanocytic lesions: activation of the ras gene seems to be associated with the nodular type of human malignant melanoma. J Cancer Res Clin Oncol 121:23-30, 1995
    • (1995) J Cancer Res Clin Oncol , vol.121 , pp. 23-30
    • Jafari, M.1    Papp, T.2    Kirchner, S.3    Diener, U.4    Henschler, D.5    Burg, G.6    Schiffmann, D.7
  • 25
    • 0031738326 scopus 로고    scopus 로고
    • N-ras mutations are common in melanomas from sun-exposed skin of humans but rare in mucosal membranes or unexposed skin
    • Jiveskog S, Ragnarsson-Olding B, Platz A, Ringborg U: N-ras mutations are common in melanomas from sun-exposed skin of humans but rare in mucosal membranes or unexposed skin. J Invest Dermatol 111:757-761, 1998
    • (1998) J Invest Dermatol , vol.111 , pp. 757-761
    • Jiveskog, S.1    Ragnarsson-Olding, B.2    Platz, A.3    Ringborg, U.4
  • 26
    • 0030112257 scopus 로고    scopus 로고
    • Analysis and significance of the malignant "eclipse" during the progression of primary cutaneous human melanomas
    • Kerbel RS, Kobayashi H, Graham CH, Lu C: Analysis and significance of the malignant "eclipse" during the progression of primary cutaneous human melanomas. J Invest Dermatol Symp Proc 1:183-187, 1996
    • (1996) J Invest Dermatol Symp Proc , vol.1 , pp. 183-187
    • Kerbel, R.S.1    Kobayashi, H.2    Graham, C.H.3    Lu, C.4
  • 28
    • 0033106484 scopus 로고    scopus 로고
    • A mechanism of repression of TGFbeta/Smad signaling by oncogenic Ras
    • Kretzschmar M, Doody J, Timokhina I, Massague J: A mechanism of repression of TGFbeta/Smad signaling by oncogenic Ras. Genes Dev 13:804-816, 1999
    • (1999) Genes Dev , vol.13 , pp. 804-816
    • Kretzschmar, M.1    Doody, J.2    Timokhina, I.3    Massague, J.4
  • 30
    • 0023681992 scopus 로고
    • Electroporation of mammalian cells with a firefly luciferase expression plasmid: Kinetics of transient expression differ markedly among cell types
    • Maxwell IH, Maxwell F: Electroporation of mammalian cells with a firefly luciferase expression plasmid: kinetics of transient expression differ markedly among cell types. DNA 7:557-562, 1988
    • (1988) DNA , vol.7 , pp. 557-562
    • Maxwell, I.H.1    Maxwell, F.2
  • 31
    • 0030221148 scopus 로고    scopus 로고
    • Interactions between Ras proteins and their effectors
    • McCormick F, Wittinghofer A: Interactions between Ras proteins and their effectors. Curr Opin Biotechnol 7:449-456, 1996
    • (1996) Curr Opin Biotechnol , vol.7 , pp. 449-456
    • McCormick, F.1    Wittinghofer, A.2
  • 32
    • 0029868841 scopus 로고    scopus 로고
    • Negative regulation of cell growth by TGF beta
    • Polyak K: Negative regulation of cell growth by TGF beta. Biochem Biophys Acta 1242:185-199, 1996
    • (1996) Biochem Biophys Acta , vol.1242 , pp. 185-199
    • Polyak, K.1
  • 33
    • 0029153609 scopus 로고
    • Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta
    • Reynisdottir I, Polyak K, lavarone A, Massague J: Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta. Genes Dev' 9:1831-1845, 1995
    • (1995) Genes Dev' , vol.9 , pp. 1831-1845
    • Reynisdottir, I.1    Polyak, K.2    Lavarone, A.3    Massague, J.4
  • 34
    • 0028153757 scopus 로고
    • Transforming growth factor beta production and responsiveness in normal human melanocytes and melanoma cells
    • Rodeck U, Bossler A, Graeven U, Fox FE, Nowell PC, Knahbe C, Kari C: Transforming growth factor beta production and responsiveness in normal human melanocytes and melanoma cells. Cancer Res 54:575-581, 1994
    • (1994) Cancer Res , vol.54 , pp. 575-581
    • Rodeck, U.1    Bossler, A.2    Graeven, U.3    Fox, F.E.4    Nowell, P.C.5    Knahbe, C.6    Kari, C.7
  • 35
    • 0033082525 scopus 로고    scopus 로고
    • Independent regulation of growth and SMAD-mediated transcription by transforming growth factor beta in human melanoma cells
    • Rodeck U, Nishiyama T, Mauviel A: Independent regulation of growth and SMAD-mediated transcription by transforming growth factor beta in human melanoma cells. Cancer Res 59:547-550, 1999
    • (1999) Cancer Res , vol.59 , pp. 547-550
    • Rodeck, U.1    Nishiyama, T.2    Mauviel, A.3
  • 36
    • 0030853288 scopus 로고    scopus 로고
    • Melanoma cell lines from different stages of progression and their biological and molecular analyses
    • Satyamoorthy K, DeJesus E, Linnenbach AJ, et al: Melanoma cell lines from different stages of progression and their biological and molecular analyses. Melanoma Res 7 (Suppl. 2):S35-S42, 1997
    • (1997) Melanoma Res , vol.7 , Issue.SUPPL. 2
    • Satyamoorthy, K.1    DeJesus, E.2    Linnenbach, A.J.3
  • 37
    • 0021958679 scopus 로고
    • Autocrine growth factors and cancer
    • Sporn MB, Roberts AB: Autocrine growth factors and cancer. Nature 313:745-747, 1985
    • (1985) Nature , vol.313 , pp. 745-747
    • Sporn, M.B.1    Roberts, A.B.2
  • 38
    • 0031551133 scopus 로고    scopus 로고
    • Signal transduction. Mad about SMADs
    • Wrana J, Pawson T: Signal transduction. Mad about SMADs. Nature 388:28-29, 1997
    • (1997) Nature , vol.388 , pp. 28-29
    • Wrana, J.1    Pawson, T.2
  • 39
    • 0026496172 scopus 로고
    • TGF beta signals through a heteromeric protein kinase receptor complex
    • Wrana JL, Attisano L, Carramo J, et al: TGF beta signals through a heteromeric protein kinase receptor complex. Cell 71:1003-1014, 1992
    • (1992) Cell , vol.71 , pp. 1003-1014
    • Wrana, J.L.1    Attisano, L.2    Carramo, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.