Cathepsin B/cystatin C complex levels in sera from patients with lung and colorectal cancer

Biological Chemistry

Volumn 382, Issue 5, 2001, Pages 805-810

  Zore, I ^a   Krasovec M ^a   Cimerman, N ^a   Kuhelj, R ^a   Werle, B ^a   Nielsen, H J ^a   Brunner N ^a   Kos, J ^a  

^a KRKA D D   (Slovenia)

Author keywords

Cathepsin B; Colorectal cancer; Complex; Cystatin C; Lung cancer

Indexed keywords

CATHEPSIN B; CYSTATIN C; HORSERADISH PEROXIDASE;

ANTIBODY DETECTION; ARTICLE; BINDING AFFINITY; CANCER GROWTH; CANCER PATIENT; CANCER STAGING; COLORECTAL CANCER; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME BINDING; ENZYME IMMUNOASSAY; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; HYPOTHESIS; LUNG CANCER; LUNG DISEASE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; REPRODUCIBILITY; SERUM; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS;

CASE-CONTROL STUDIES; CATHEPSIN B; COLORECTAL NEOPLASMS; CYSTATINS; CYSTEINE PROTEINASE INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; LUNG NEOPLASMS; PROTEIN BINDING; SENSITIVITY AND SPECIFICITY;

EID: 0034935190     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2001.097     Document Type: Article

References (34)

1. Isolation of six cysteine proteinase inhibitors from human urine
2. Cathepsin B activity regulation
3. Enzymatically active cathepsin B dissociating from its inhibitor complexes is elevated in blood plasma of patients with septic shock and some malignant tumors
4. The role of kininogens as cysteine proteinase inhibitors in local and systemic inflammation
5. Coupling of enzyme to antibodies and antigens
6. The cystatins: A new class of peptidase inhibitors
7. Interactions of cystatin C variants with papain and human cathepsins B, H and L
8. ELISa for complexes between urokinase-type plasminogen activator and its receptor in lung cancer tissue extracts
9. Complexes between urokinase-type plasminogen activator and its receptor in blood as determined by enzyme-linked immunosorbent assay
10. Changes in serum cathepsin B-like activity in patients with colorectal cancer
11. Proteases - Invasion and more
12. ELISA for complexes of urokinase-type and tissue-type plasminogen activators with their type-1 inhibitor (uPA-ΑPAI-1, tPAΟPAI-1)
13. Elevations in cathepsin B protein and enzyme activity occur independently of glycosylation during colorectal tumor progresion
14. Cathepsin B: Multiple enzyme forms from a single gene and their relation to cancer
15. Cysteine proteinases and their endogenous inhibitors: Target proteins for prognosis, diagnosis and therapy in cancer: A Review
16. Cathepsins B, H and L and their inhibitors stefin A and cystatin C in sera of melanoma patients
17. Prognostic values of cathepsin B and carcinoembryonic antigen in sera of patients with colorectal cancer
18. Serum cystatin C, a new marker of glomerular filtration rate, is increased during malignant progression
19. Cysteine proteinase inhibitors stefin A, stefin B and cystatin C in sera from patients with colorectal cancer: Relation to prognosis
20. Cysteine proteinases and their inhibitors in extracellular fluids: Markers for diagnosis and prognosis in cancer
21. Multiple forms of cathepsin B in human lung cancer
22. The preparation of catalytically active human cathepsin B from its precursor expressed in Echerichia coli in the form of inclusion bodies
23. Cysteine proteinases in cancer progression and their clinical relevance for prognosis
24. Inhibitory properties of low molecular mass cysteine proteinase inhibitors from human sarcoma
25. Chemotherapie des nichkleinzelligen Lungenkarcinoms
26. Cathepsin L is capable of truncating cystatin C of 11 N-terminal amino acids
27. Radiotherapie des Bronchialkarzinoms
28. Cysteine peptidase inhibitors and activator(s) in urine of patients with colorectal cancer
29. Regulation of lysosome endopeptidases in malignant neoplasia
30. Cathepsin B activity in human lung tumor cell lines: Ultrastructural localisation, pH sensitivity and inhibitor status at the cellular level
31. Enzyme linked immunosorbent assay for detection of cathepsin-kininogen complexes in human plasma
32. Kinetics of the pH-induced inactivation of human cathepsin L
33. Cathepsin B in human tumor progression: A review
34. Cathepsin B-like activity as a serum tumor marker in ovarian carcinoma