Prognostic values of cathepsin B and carcinoembryonic antigen in sera of patients with colorectal cancer

Clinical Cancer Research

Volumn 4, Issue 6, 1998, Pages 1511-1516

  Kos, Janko ^a,b   Nielsen, Hans Jørgen ^c   Krašovec, Marta ^b   Christensen, Ib Jarle ^d   Cimerman, Nina ^b   Stephens, Ross W ^d   Brünner, Nils ^d  

^a JO EF STEFAN INSTITUTE   (Slovenia)

^b KRKA   (Slovenia)

^c HVIDOVRE HOSPITAL   (Denmark)

^d FINSEN LABORATORY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CATHEPSIN B;

ADULT; AGED; ARTICLE; CANCER SURVIVAL; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; SURVIVAL TIME;

ADULT; AGED; AGED, 80 AND OVER; CARCINOEMBRYONIC ANTIGEN; CATHEPSIN B; COLORECTAL NEOPLASMS; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM STAGING; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RISK FACTORS; SURVIVAL RATE; TIME FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 0031749310     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Duffy, M. J. Proteases as prognostic markers in cancer. Clin. Cancer Res., 2: 613-618, 1996.
2. Pagano, M., Capony, F., and Rochefort, H. La pro-cathepsin D peut activer in vitro la pro-cathepsin B secretee par les cancers ovariens. C. R. Seances Acad. Sci. Ser. III Sci. Vie, 309: 7-12, 1990.
3. Kobayashi, H., Schmitt, M., Goretzki, L., Chucholowski, N., Calvete, J., Kramer, M., Guncler, W. A., Janicke, F., and Graeff, H. Cathepsin B efficiently activates the soluble and the tumor cell receptor-bound form of the proenzyme urokinase-type plasminogen activator (pro-uPA). J. Biol. Chem., 266: 5147-5152, 1990.
4. Lah, T. T., Buck, M. R., Honn, K. V., Crissman, J. D., Rao, N. C., Liotta, L. A., and Sloane, B. F. Degradation of laminin by human tumour cathepsin B. Clin. Exp. Metastasis, 7: 461-468, 1989.
5. Burleigh, M. C., Barrett, A. J., and Lazarus, G. S. Cathepsin Bl. A lysosomal enzyme that degrades native collagen. Biochem. J., 137: 387-398, 1974.
6. Mason, R. W., Jonson, D. A., Barrett, A. J., and Chapman, H. A. Elastinolytic activity of human cathepsin L. Biochem. J., 233: 925-927, 1986.
7. Morrison, R. I. G., Barrett, A. J., Dingle, J. T., and Prior, D. Cathepsins B1 and D action on human cartilage proteoglycans. Biochim. Biophys. Acta, 302: 411-419, 1973.
8. Turk, V., and Bode, W. Human cysteine proteinases and their inhibitors, stefins and cystatins. In: F. X. Aviles (ed.), Innovations in Proteases and Their Inhibitors, pp. 47-59. Berlin: W. de Gruyter, 1993.
9. Uchiyama, Y., Waguri, S., Sato, N., Watanabe, T., Ishido, K., and Kominami, E. Cell and tissue distribution of lysosomal cysteine proteinases, cathepsins B, H and L, and their biological roles. Acta Histochem. Cytochem., 27: 287-308, 1994.
10. Schmitt, M., Janicke, F., and Graeff, F. Tumor-associated proteases. Fibrinolysis, 6 (Suppl. 4): 3-26, 1992.
11. Sloane, B. F., Moin, K., and Lah, T. T. Regulation of lysosomal endopeptidases in malignant neoplasia. In: T. G. Pretlow and T. P. Pretlow (eds.), Biochemical and Molecular Aspects of Selected Cancers, pp. 411-472. New York: Academic Press, 1994.
12. Thomssen, C., Schmitt, M., Goretzki, L., Oppelt, P., Janicke, P., Pache, L., and Graeff, H. Prognostic value of the cysteine proteases cathepsin B and L in human breast cancer. Clin. Cancer Res., 1: 741-746, 1995.
13. Budihna, M., Strojan, P., Šmid, L., Škrk, J., Vrhovec, I., Župevc, A., Rudolf, Z., Žargi, M., Krašovec, M., Svetic, B., Kopitar-Jerala, N., and Kos, J. Prognostic value of cathepsins B, H, L, D and their endogenous inhibitors stefins A and B in head and neck carcinoma. Biol. Chem. Hoppe-Seyler, 377: 385-390, 1996.
14. Campo, E., Munoz, J., Miquel, R., Palacin, A., Cardesa, A., Sloane, B. F., and Emmert-Buck, M. R. Cathepsin B expression in colorectal carcinomas correlates with tumor progression and shortened patient survival. Am. J. Pathol., 745: 310-309, 1994.
15. Sukoh, N., Abe, S., Ogura, S., Isobe, H., Takekawa, H., Inoue, K., and Kawakami, Y. Immunochemical study of cathepsin B. Cancer (Phila.), 74: 46-51, 1994.
16. Ebert, W., Knoch, H., Werle, B., Trefz, G., Muley, T. H., and Spiess, E. Prognostic value of increased lung tumor tissue cathepsin B. Anticancer Res., 14: 895-900, 1994.
17. Gabrijelčič, D., Svetic, B., Spaić, D., Škrk, J., Budihna, M., Dolenc, I., Popović, T., Cotič, V., and Turk, V. Cathepsins B, H, and L in human breast carcinoma. Eur. J. Clin. Chem. Clin. Biochem., 30: 69-74, 1992.
18. Tumminello, F. M., Pizzolanti, G., Gebbia, N., and Leto, G. Stefin A and cathepsin B and L circulating serum levels in patients with malignant or non-malignant liver diseases: a preliminary report. Med. Sci. Res., 23: 741-742, 1995.
19. Leto, G., Tumminello, F. M., Pizzolanti, G., Montalto, G., Soresi, M., Carroccio, A., Ippolito, S., and Gebbia, N. Lysosomal aspartic and cysteine proteinases serum levels in patients with pancreatic cancer or pancreatitis. Pancreas, 14: 22-27, 1997.
20. Kos, J., Štabuc, B., Schweiger, A., Krašovec, M., Cimerman, N., Kopitar-Jerala, N., and Vrhovec, I. Cathepsins B, H, L, and their inhibitors stefin A, and cystatin C in sera of melanoma patients. Clin. Cancer Res., 3: 1815-1822, 1997.
21. Keppler, D., Fondaneche, M. C., Dalet-Fumeron, V., Pagano, M., and Burtin, P. Immunohistochemical and biochemical study of a cathepsin B like proteinase in human colonie cancers. Cancer Res., 48: 6855-6862, 1988.
22. Sheahan, K., Shuja, S., and Murnane, M. J. Cysteine protease activities and tumor development in human colorectal carcinoma. Cancer Res., 49: 3809-3814, 1989.
23. Murnane, M. J., Sheahan, K., Ozdemirli, M., and Shuja, S. Stage-specific increases in cathepsin B messenger RNA content in human colorectal carcinoma. Cancer Res., 51: 1137-1142, 1991.
24. Emmert-Buck, M. R., Roth, M. J., Zhuang, Z., Champo, E., Rozhin, J., Sloane, B. F., Liotta, L. A., and Stetler-Stevenson, W. G. Increased gelatinase A (MMP-2) and cathepsin B activity in invasive tumor regions of human colon cancer samples. Am. J. Pathol., 145: 1285-1290, 1994.
25. Corticchiato, O., Cajot, J. F., Abrahamson, M., Chan, S. J., and Keppler, D. Cystatin C and cathepsin B in human colon carcinoma: expression by cell lines and matrix degradation. Int. J. Cancer, 52: 645-652, 1992.
26. Moertel, C. G., O'Fallon, J. R., Go, V. L. W., O'Connel, M. J., and Thynne, G. S. The preoperative carcinoembryonic antigen test in the diagnosis, staging and prognosis of colorectal cancer. Cancer (Phila.), 58: 603-610, 1986.
27. Fletcher, R. H. Carcinoembryonic antigen. Ann. Int. Med., 104: 66-73, 1986.
28. Nap, M., Hammarstrom, M. J., Bromer, O., Hammarstrom, S., Wagener, C., Handt, S., Schreyer, M., Mach, J. P., Buchegger, F., Kleist, S., Grunert, F., Seguin, P., Fuks, A., Holm, R., and Lamerz, R. Specificity and affinity of monoclonal antibodies against carcinoembryonic antigen. Cancer Res., 52: 2329-2339, 1992.
29. Kos, J., Šmid, L., Krašovec, M., Svetic, B., Lenarčič, B., Vrhovec, I., Škrk J., and Turk, V. Lysosomal proteases cathepsins D, B, H, L and their inhibitors stefins A and B in head and neck cancer. Biol. Chem. Hoppe-Seyler, 376: 401-405, 1995.
30. Kaplan, E. L., and Meier, P. Nonparametric estimation from incomplete observation. J. Am. Stat. Assoc., 53: 457-481, 1958.
31. Cox, D. R. Regression models and life tables. J. R. Stat. Soc., 187: 187-220, 1972.
32. Willet, W. The search for the causes of breast and colon cancer. Nature (Lond.), 338: 386-394, 1989.
33. Klapdor, R. Colorectal carcinoma. In: R. Klapdor (ed.), Tumor Markers in Clinical Oncology: An Overview, pp. 97-114. Torino, Italy: Sorin Biomedica S. P. A., 1994.
34. Starkley, P. M., Fletcher, T. C., and Barrett, A. J. Evolution of α2-macroglobulin. Purification and characterisation of protein homologous with human α2-macroglobulin from plaice (Pleuromides platessa) plasma. Biochem. J., 205: 97-104, 1982.
35. Hirano, T., Manabe, T., and Takeuchi, S. Serum cathepsin B levels and urinary excretion of cathepsin B in the cancer patients with remote metastasis. Cancer Lett., 70: 41-44, 1993.
36. Sloane, B. F., Moin, K., Krepela, E., and Rozhin, J. Cathepsin B and its endogenous inhibitors: the role in tumor malignancy. Cancer Metastasis Rev., 9: 333-352, 1990.