Ionizing radiation damage repair: A role for topoisomerase?

Mutagenesis

Volumn 16, Issue 4, 2001, Pages 365-368

  Cortes F ^a   Pastor, N ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE;

CANCER CHEMOTHERAPY; CHROMATIN; CHROMOSOME CONDENSATION; CHROMOSOME SEGREGATION; DNA METABOLISM; DNA REPAIR; DNA REPLICATION; DNA TRANSCRIPTION; IONIZING RADIATION; LETTER; MAMMAL CELL; PRIORITY JOURNAL;

DNA; DNA REPAIR; DNA REPLICATION; DNA TOPOISOMERASES, TYPE I; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; LYMPHOCYTES; RADIATION, IONIZING;

MAMMALIA;

EID: 0034921706     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Letter

References (47)

1. Illegitimate recombination mediated by calf thymus DNA topoisomerase II in vitro
2. DNA repair and transcriptional activity in genes
3. Down-regulation of topoisomerase I in mammalian cells following ionizing radiation
4. Enzymatic restriction of mammalian cell DNA using PvuII and BamHI: Evidence for the double-strand break origin of chromosomal aberrations
5. Association of crossover points with topoisomerase I cleavage sites: A model for nonhomologous recombination
6. Hypersensitivity of lymphoblastoid lines derived from ataxia telangiectasia patients to the induction of chromosomal aberrations by etoposide (VP-16)
7. Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II
8. Novobiocin: An inhibitor of the repair of UV-induced but not X-ray-induced damage in mammalian cells
9. Molecular studies on the nature of the repair defect in ataxia-telangiectasia and their implications for cellular radiobiology
10. DNA topoisomerases and DNA repair
11. Effects of topoisomerase II inhibition in lymphoblasts from patients with progeroid and 'chromosome instability' syndromes
12. Poly(ADP-ribosylation) of a DNA topoisomerase
13. RecQ-like helicases: The DNA replication checkpoint connection
14. Suramin inhibits the phosphorylation and catalytic activity of DNA topoisomerase II in human lung cancer cells
15. The cell cycle-coupled expression of topoisomerase IIα during S phase is regulated by mRNA stability and is disrupted by heat shock or ionizing radiation
16. Intra- and intermolecular strand transfer by HeLa DNA topoisomerase I
17. Effects of ICRF-193, a catalytic inhibitor of DNA topoisomerase II, on sister chromatid exchange
18. RecQ helicase and topoisomerase III comprise a novel DNA strand passage function: A conserved mechanism for control of DNA recombination
19. Bufalin reduces the level of topoisomerase II in human leukemia cells and effects the cytotoxicity of anticancer drugs
20. Bacteriophage T4 DNA topoisomerase mediates illegitimate recombination in vitro
21. Illegitimate recombination mediated in vitro by DNA gyrase of Escherichia coli: Structure of recombinant DNA molecules
22. Changes in topoisomerase I activity after irradiation of lymphoid cells
23. Biochemical and genetic analysis of the Chinese hamster mutants irs1 and irs2 and their comparison to cultured ataxia telangiectasia cells
24. Cellular and chromosomal hypersensitivity to DNA crosslinking agents and topoisomerase inhibitors in the radiosensitive Chinese hamster irs mutants: Phenotypic similarities to ataxia telangiectasia and Fanconi's anaemia cells
25. DNA topoisomerase I from calf thymus is inhibited in vitro by poly(ADP-ribosylation)
26. Molecular mechanisms of DNA double-strand break repair
27. DNA topoisomerase I in oncology: Dr Jekyll or Mr Hyde?
28. Defective DNA topoisomerase II in ataxia-telangiectasia cells
29. A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity
30. Altered topoisomerase I and II activities in suramin-resistant lung fibrosarcoma cells
31. In vitro sequence-dependent synergistic effect of suramin and camptothecin
32. The top3(+) gene is essential in Schizosaccharomyces pombe and the lethality associated with its loss is caused by Rad12 helicase activity
33. Radiation sensitivity correlates with changes in DNA supercoiling and nucleoid protein content in cells of three Chinese hamster cell lines
34. DNA topoisomerase-targeting antitumour drugs can be studied in yeast
35. Radiosensitivity in ataxia-telangiectasia, a new explanation
36. Topoisomerase activities and levels in irradiated Chinese hamster AA8 cells and in its radiosensitive mutant EM9
37. Effect of the topoisomerase-II inhibitor etoposide on meiotic recombination in male mice
38. p53 regulates the minimal promoter of the human topoisomerase II alpha gene
39. Irradiation with ultraviolet light and γ-rays increases the level of DNA topoisomerase IIα in nuclei of normal and xeroderma pigmentosum fibroblasts
40. Subnuclear distribution of DNA topoisomerase I and Bax protein in normal and xeroderma pigmentosum fibroblasts after irradiation with UV light and gamma rays or treatment with topotecan
41. A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair and an extraordinary baseline frequency of sister-chromatid exchange
42. DNA topoisomerases
43. DNA topoisomerases
44. Inhibition of DNA topoisomerase alpha gene expression by the p53 tumor suppressor
45. Mammalian mutants defective in the response to ionizing radiation-induced DNA damage
46. Topoisomerase I involvement in illegitimate recombination in Saccharomyces cerevisiae