Phorbol myristate acetate stimulates the dimerization of CD44 involving a cysteine in the transmembrane domain

Journal of Immunology

Volumn 159, Issue 6, 1997, Pages 2702-2711

  Liu, Dacai ^a   Sy, Man Sun ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; CYSTEINE; HERMES ANTIGEN; HYALURONIC ACID; PHORBOL 13 ACETATE 12 MYRISTATE;

ARTICLE; CELL MEMBRANE; CHEMISTRY; DIMERIZATION; DRUG EFFECT; HUMAN; LEUKEMIA CELL LINE; METABOLISM; SIGNAL TRANSDUCTION;

ANTIGENS, CD44; CARCINOGENS; CELL MEMBRANE; CYSTEINE; DIMERIZATION; HUMANS; HYALURONIC ACID; JURKAT CELLS; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE;

EID: 0031571729     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Hynes, R. O. 1992. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69:11.
2. Diamond, M. S., and T. A. Springer. 1994. The dynamic regulation of integrin adhesiveness. Curr. Biol. 4:506.
3. Ginsberg, M. H., X. Du., and E. D. Plow. 1992. Inside-out integrin signaling. Curr. Opin. Cell Biol. 4:766.
4. Haynes, B. F., M. J. Telen, L. P. Hale, and S. M. Denning. 1989. CD44 a molecule involved in leukocyte adherence and T cell activation. Immimol. Today 11:80.
5. Lesley, J., R. Hyman, and P. W. Kincade. 1993. CD44 and its interaction with extracellular matrix. Adv. Immunol. 54:271.
6. Sy, M. S., D. Liu, R. Schiavone, J. Ma, H. Mori, and Y. J. Guo. 1995. Interactions between CD44 and hyaluronic acid: their role in tumor growth and metastasis. In Attempts to Understand Metastasis Formation. Part 3. Therapeutic Approaches for Metastasis Treatment. U. Gümhert, P. M. Schlag, and W. Birchmeir, eds. Vol 213 of Current Topics in Microbiology and Immunology. Springer-Verlag, New York, p. 219.
7. CIBA Foundation Symposium Staff. 1989. The Biology of Hyaluronan. CIBA Foundation Symposium Series No. 143. John Wiley and Sons Ltd., New York.
8. Laurent, T. C., and J. R. E. Fraser. 1992. Hyaluronan. FASEB J. 6:2397.
9. Underhill, C. 1992. CD44: the hyaluronan receptor. J. Cell Sci. 103:293.
10. Underhill, C. B., and B. P. Toole. 1979. Binding of hyaluronate to the surface of cultured cells. J. Cell Biol. 82:475.
11. Underhill, C. B., and A. Dorfman. 1978. The role of hyaluronic acid in intercellular adhesion of cultured mouse cells. Exp. Cell Res. 117:155.
12. Underhill, C. B. 1982. Interaction of hyaluronate with the surface of simian virus 4-transformed 3T3 cells: aggregation and binding studies. J. Cell Sci. 56:177.
13. Underhill, C. B., G. Chi-Rosso, and B P. Toole. 1983. Effects of detergent solubilization on the hyaluronate-binding protein from membranes of simian virus 40 transformed 3T3 cells. J. Biol. Chem. 258:8086.
14. Hathcock, K. S., H. Hirano, S. Murakami, and R. J. Hodes. 1993. CD44 expression on activated B cells: differential capacity for CD44 dependent binding to hyaluronic acid. J. Immunol. 151:6712.
15. Hyman, R., J. Lesley, and R. Schulte. 1992. Somatic cell mutants distinguish CD44 expression and hyaluronic acid binding. Immunogenetics 33:329.
16. Liao, H. X., M. C. Levesque, K. Patton, B. Bergamo, D. Jones, M. A. Moody, N. M. J. Telen, and B. F. Haynes. 1993. Regulation of human CD44H and CD44E isoform binding to hyaluronan by phorbol myristate acetate and anti-CD44 monoclonal and polyclonal antibodies. J. Immunol. 151:6490.
17. Liu, D., X. Z. Dong, H. Mori, and M. S. Sy. 1996. Physiologic requirements and the role of cytoplasmic domain of CD44 in the interactions between CD44 and hyalduronic acid. Cell. Immunol. 174:73.
18. Liu, D., and M. S. Sy. 1996. A cysteine residue in the transmembrane domain of CD44 is essential for binding of hyaluronic acid. J. Exp. Med. 183:1987.
19. Lesley, J., Q. He, K. Miyake, A. Hamann, R. Hyman, and P. W. Kincade. 1992. Requirements for hyaluronic acid binding by CD44: a role for the cytoplasmic domain and activation by antibody, J. Exp. Med. 175:257.