Autoimmune melanocyte destruction in vitiligo

Laboratory Investigation

Volumn 81, Issue 8, 2001, Pages 1061-1067

  Van den Wijngaard, René ^a   Wankowicz Kalinska, Anna ^a   Pals, Steven ^a   Weening, Jan ^a   Das, Pranab ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOIMMUNITY; CELL DESTRUCTION; CELLULAR IMMUNITY; DNA DAMAGE; HEREDITY; HUMORAL IMMUNITY; IMMUNE RESPONSE; MELANOCYTE; ONTOGENY; PATHOGENESIS; PRIORITY JOURNAL; SHORT SURVEY; VITILIGO;

AUTOANTIBODIES; AUTOIMMUNE DISEASES; HUMANS; MELANOCYTES; T-LYMPHOCYTES; VITILIGO;

EID: 0034887406     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3780318     Document Type: Article

References (91)

1. Further evidence for involvement of both cell mediated and humoral immunity in generalized vitiligo
2. Abnormal expression of MHC class II and ICAM-1 by melanocytes in vitiligo
3. Melanoma cells and normal melanocytes share antigens recognized by HLA-A2-restricted cytotoxic T cell clones from melanoma patients
4. High frequency hearing and reflex latency in patients with pigment disorder
5. An immunohistological study of cutaneous lymphocytes in vitiligo
6. Accumulation of identical T cells in melanoma and vitiligo-like leukoderma
7. Coupling and uncoupling of tumor immunity and autoimmunity
8. Vitiligo is associated with HLA-A2 and HLA-Dw7 in the Slovak populations
9. Vitiligo with raised inflammatory border
10. Role of melanin as a scavenger of active oxygen species
11. Prognostic significance of hypopigmentation in malignant melanoma
12. Molecular mechanisms of anti-inflammatory action of glucocorticoids
13. A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas
14. Localization of Th-cell subsets in inflammation: Differential thresholds for extravasation of Th1 and Th2 cells
15. Role of oxygen intermediates in UV-induced epidermal cell injury
16. Studies on vitiligo. II. Familial aggregation and genetics
17. A symbiotic concept of autoimmunity and tumour immunity: Lessons from vitiligo
18. Vitiligo is associated with HLA-DR4 in black patients: A preliminary report
19. Autoantibodies to tyrosinase: The bridge between melanoma and vitiligo
20. Association of HLA-DR4 with vitiligo
21. Vitiligo with raised borders
22. In vivo destruction of melanocytes by the IgG fraction of serum from patients with vitiligo
23. Vitiligo in diabetes mellitus
24. Mononuclear cell subpopulations and infiltrating lymphocytes in erythema dyschromicum perstans and vitiligo
25. Implicating a role for immune recognition of self in tumor rejection: Passive immunization against the brown locus protein
26. Relation between the incidence and level of pigment cell antibodies and disease activity in vitiligo
27. Biochemical control of melanogenesis and melanosomal organization
28. High frequency of thyroid dysfunction in patients with vitiligo
29. A critical role for Fas ligand in the active suppression of systemic immune responses by ultraviolet radiation
30. Clonal expansion of Melan A-specific cytotoxic T lymphocytes in a melanoma patient responding to continued immunization with melanoma-associated peptides
31. Biology of melanocytes
32. A cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphism is associated with autoimmune Addison's disease in English patients
33. Analysis of a microsatellite polymorphism of the cytotoxic T-lymphocyte antigen-4 gene in patients with vitiligo
34. Detection of tyrosinase autoantibodies in patients with vitiligo using 35S-labeled recombinant human tyrosinase in a radioimmunoassay
35. Autoantibodies to human melanocyte-specific protein pmel17 in the sera of vitiligo patients: A sensitive and quantitative radioimmunoassay (RIA)
36. Autoantibodies to tyrosinase-related protein-1 detected in the sera of vitiligo patients using a quantitative radiobinding assay
37. Supranuclear melanin caps reduce ultraviolet induced DNA photoproducts in human epidermis
38. A CTLA-4 gene polymorphism is associated with both Graves disease and autoimmune hypothyroidism
39. Vitiligo
40. Mechanisms of ultraviolet (UV) B and UVA phototherapy
41. Transgene expression of steel factor in the basal layer of epidermis promotes survival, proliferation, differentiation, and migration of melanocyte precursors
42. Keratinocytes suppress transforming growth factor-beta1 expression by fibroblasts in cultured skin substitutes
43. A novel, antigen-presenting function of melanocytes and its possible relationship to hypopigmentary disorders
44. Presence of T cells and macrophages in inflammatory vitiligo skin parallels melanocyte disappearance
45. Presence or absence of melanocytes in vitiligo lesions: An immunohistochemical investigation
46. Phagocytosis by normal human melanocytes in vitro
47. Vitiligo
48. The health impact of solar radiation and prevention strategies: Report of the Environment Council
49. Pattern of familial aggregation of vitiligo
50. The role of CTLA-4 in the regulation of T cell immune responses
51. DNA repair, DNA replication, and UV mutagenesis
52. Vitiligo and the HLA system
53. Vitiligo with raised borders
54. Disorders of melanocytes
55. Immune response to a differentiation antigen induced by altered antigen: A study of tumor rejection and autoimmunity
56. Antibodies to normal human melanocytes in vitiligo
57. Detection of antibodies to melanocytes in vitiligo by specific immuno-precipitation
58. Regulation of E- and P-cadherin expression correlated with melanocyte migration and diversification
59. Nonsurgical repigmentation therapies in vitiligo: Meta-analysis of the literature
60. Vitiligo in patients with metastatic melanoma: A good prognostic sign
61. Evidence for immunologic mechanisms in human vitiligo: Patients' sera induce damage to human melanocytes in vitro by complement-mediated damage and antibody-dependent cellular cytotoxicity
62. High frequency of skin-homing melanocyte-specific cytotoxic T lymphocytes in autoimmune vitiligo
63. Vaccination with a recombinant vaccinia virus encoding a "self" antigen induces autoimmune vitiligo and tumor cell destruction in mice: Requirement for CD4(+) T lymphocytes
64. 312-Nanometer ultraviolet B light (narrow-band UVB) induces apoptosis of T cells within psoriatic lesions
65. Ocular manifestations of pigmentary disorders
66. A unique phenotype of skin-associated lymphocytes in humans: Preferential expression of the HECA-452 epitope by benign and malignant T cells at cutaneous sites
67. High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals
68. Psychological reaction to chronic skin disorders: A study of patients with vitiligo
69. Free radicals in biology: Oxidative stress and the effects of ionizing radiation
70. Human melanoma-reactive CD4+ and CD8+ CTL clones resist Fas ligand-induced apoptosis and use Fas/Fas ligand-independent mechanisms for tumor killing
71. Cancer vaccines based on the identification of genes encoding cancer regression antigens
72. Tyrosinase: A comprehensive review of its mechanism
73. Expression of different immunological markers by cultured human melanocytes
74. The role of tyrosinase in autoimmune vitiligo
75. A melanosomal membrane protein is a cell surface target for melanoma therapy
76. Immunopathology of vitiligo vulgaris, Sutton's leukoderma and melanoma-associated vitiligo in relation to steroid effects. II. The IgG and C3 deposits in the skin
77. Local immune response in skin of generalized vitiligo patients: Destruction of melanocytes is associated with the prominent presence of CLA+T cells at the perilesional site
78. HLA associations in vitiligo patients in the Dutch population
79. Intracellular sorting and targeting of melanosomal membrane proteins: Identification of signals for sorting of the human brown locus protein, gp75
80. CTL specific for the tyrosinase autoantigen can be induced from healthy donor blood to lyse melanoma cells
81. A role for a melanosome transport signal in accessing the MHC class II presentation pathway and in eliciting CD4+ T cell responses
82. Tumor immunity and autoimmunity induced by immunization with homologous DNA
83. Soluble and cell-bound forms of steel factor activity play distinct roles in melanocyte precursor dispersal and survival on the lateral neural crest migration pathway
84. The cytoplasmic tail of the mouse brown locus product determines intracellular stability and export from the endoplasmic reticulum
85. Vitiligo with raised inflammatory borders: Involvement of T cell immunity and keratinocytes expressing MHC class II and ICAM-1 molecules
86. Three modes of melanosome transfers in Caucasian facial skin: Hypothesis based on an ultrastructural study
87. Melanocyte destruction after antigen-specific immunotherapy of melanoma: Direct evidence of T cell-mediated vitiligo
88. Coexistence and relationship of antikeratinocyte and antimelanocyte antibodies in patients with non-segmental-type vitiligo
89. Expression and secretion of leukocyte chemotactic cytokines by normal human melanocytes and melanoma cells
90. Melan-A/MART-1(51-73) represents an immunogenic HLA-DR4-restricted epitope recognized by melanoma-reactive CD4(+) T cells
91. Prevalence of autoimmune atrophic gastritis in vitiligo