Genetic predisposition to coronary artery disease

Current Opinion in Cardiology

Volumn 16, Issue 4, 2001, Pages 251-260

  Scheuner, Maren T ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HOMOCYSTEINE; LIPOPROTEIN A; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; CORONARY ARTERY DISEASE; DNA DETERMINATION; FAMILY HISTORY; GENETIC COUNSELING; GENETIC PREDISPOSITION; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; NONHUMAN; PATIENT EDUCATION; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; RISK FACTOR;

CORONARY ARTERIOSCLEROSIS; DISEASE MODELS, ANIMAL; FEMALE; GENETIC COUNSELING; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LIFE STYLE; RISK FACTORS; TWIN STUDIES;

EID: 0034886458     PISSN: 02684705     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001573-200107000-00006     Document Type: Review

References (177)

1. Lifetime risk of developing coronary heart disease
2. Prospects for cardiovascular research
3. Atherogenesis: Current understanding of the causes of atheroma
4. Thrombus formation on atherosclerotic plaques: Pathogenesis and clinical consequences
5. The future of genetic studies of complex human diseases
6. Spectrum of LDL receptor gene mutations in heterozygous familial hypercholesterolemia
7. Molecular genetics of the LDL receptor gene in familial hypercholesterolemia
8. Association of mutation in the apolipoprotein B gene with hypercholesterolemia and the risk of ischemic heart disease
9. The familial occurrence of hypertension and coronary artery disease with observations concerning obesity and diabetes
10. Familial patterns in ischaemic heart disease
11. The increased risk of death from ischaemic heart disease in first-degree relatives of 121 men and 96 women with ischaemic heart disease
12. Familial occurrence of coronary heart disease: Effect of age at diagnosis
13. Risk factors for coronary artery disease in families of young men with myocardial infarction
14. Familial aggregation of coronary heart disease and its relation to known genetic risk factors
15. The relationship of reported parental history to the incidence of coronary heart disease in the Western Collaborative Group Study
16. A prospective study of parental history of myocardial infarction and coronary artery disease in men
17. Family history of heart attack as an independent predictor of death due to cardiovascular disease
18. A prospective study of parental history of myocardial infarction and coronary heart disease in women
19. Coronary risk associated with age and sex of parental heart disease in the Framingham Study
20. Parental death from heart disease and the risk of heart attack
21. Family history as an independent risk factor for incident coronary artery disease in a high-risk cohort in Utah
22. Genetics of atherosclerosis. Studies of families with xanthoma and unselected patients with coronary artery disease under the age of fifty years
23. Risk factors for coronary artery disease in children of affected families
24. Coronary artery disease and its risk factors in families of young men with angina pectoris and in controls
25. Hereditary aspects of coronary artery disease
26. Lp(a) phenotypes, other lipoprotein parameters, and a family history of coronary heart disease in middle-aged males
27. Risk factors in siblings of people with premature coronary heart disease
28. Lipoprotein(a) and coronary heart disease: A prospective case-control study in a general population sample of middle aged men
29. Occlusive coronary artery disease and parental history of myocardial infarction
30. Coronary risk factors and the severity of angiographic coronary artery disease in members of high-risk pedigrees
31. Family history of coronary heart disease and pre-clinical carotid artery atherosclerosis in African Americans and Whites: The ARIC Study
32. Arterial abnormalities in the offspring of patients with premature myocardial infarction
33. Genetic-epidemiologic study of early-onset ischemic heart disease
34. The inheritance of liability to certain diseases estimated from the incidence among relatives
35. Measures of twin concordance
36. Twin studies on coronary heart disease and its risk factors
37. Hereditary factors and 'angina pectoris'
38. Coronary heart disease in male twins: Hereditary and environmental factors in concordant and discordant pairs
39. Concordance for mortality with special reference to ischemic heart disease and cerebrovascular disease
40. Genetic susceptibility to death from coronary heart disease in a study of twins
41. Genetic analysis of cardiovascular disease risk factor clustering in adult female twins
42. Concordance of ischemic heart disease in the NHLBI twin study after 14-18 years of follow-up
43. Genetic markers for studies of atherosclerosis and related risk factors
44. Lp(a) lipoprotein: A monogenic risk factor for caardiovascular disease
45. Apolipoprotein(a) kringle IV repeat number predicts risk for coronary heart disease
46. Apolipoprotein E polymorphisms affect atherosclerosis in young males
47. Apolipoprotein E polymorphism and atherosclerosis risk
48. Polymorphisms of the apolipoprotein E gene and severity of coronary artery disease defined by angiography
49. Apolipoprotein E alleles and risk of coronary disease. A meta-analysis
50. The role of the apolipoprotein E polymorphism in the prediction of coronary artery disease age of onset
51. Independent association of APOE gene promoter polymorphism with increased risk of myocardial infarction and decreased APOE plasma concentrations - The ECTIM study
52. The role of a common variant of the cholesterol ester transfer protein gene in the progression of coronary atherosclerosis
53. Increased coronary heart disease in Japanese-American men with mutation in the cholesterol ester transfer protein gene despite increased HDL levels
54. Interaction of the cholesterol ester transfer protein 1405V polymorphism with alcohol consumption in smoking and non-smoking healthy men, and the effect on plasma HDL cholesterol and apoAI concentration
55. The asp9asn mutation in the lipoprotein lipase gene is associated with increased progression of coronary atherosclerosis
56. DNA polymorphisms in two paraoxonase genes (PON1 and PON2) are associated with the risk of coronary heart disease
57. Angiotensinogen T174M and M235T gene polymorphisms are associated with the extent of coronary atherosclerosis
58. Angiotensinogen M235T polymorphism is associated with plasma angiotensinogen and cardiovascular disease
59. Genetic polymorphisms in the renin-angiotensin system: Relevance for cardiovascular disease
60. Synergistic effects of angiotensin-converting enzyme and angiotensin-II type 1 receptor gene polymorphisms on risk of myocardial infarction
61. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction
62. Large-scale test of hypothesized associations between the angiotensin-converting-enzyme insertion/deletion polymorphism and myocardial infarction in about 5000 cases and 6000 controls
63. Prevalence of familial mild hyperhomocysteinemia
64. Improved identification of heterozygotes for homocystinuria due to cystathionine synthase deficiency by the combination of methionine loading and enzyme determination in cultured fibroblasts
65. Heterozygosity for homocystinuria in premature peripheral and cerebral occlusive arterial disease
66. Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease
67. A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
68. Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease
69. Hormone replacement therapy, prothrombotic mutations, and the risk of incident nonfatal myocardial infarction in postmenopausal women
70. Factor V Leiden (resistance to activated protein C) increases the risk of myocardial infarction in young women
71. Association of the R485K polymorphism of the factor V gene with poor response to activated protein C and increased risk of coronary artery disease in the Chinese population
72. The decanucleotide insertion/deletion polymorphism in the promoter region of the coagulation factor VII gene and the risk of familial myocardial infarction
73. Factor VII Gene polymorphism, factor VII levels, and prevalent cardiovascular disease. The Framingham Heart Study
74. Polymorphisms in the factor VII gene and the risk of myocardial infarction in patients with coronary artery disease
75. The role of beta-fibrinogen genotype in determining plasma fibrinogen levels in young survivors of myocardial infarction and healthy controls from Sweden
76. Gene-environment interaction in the determination of levels of haemostatic variables involved in thrombosis and fibrinolysis
77. A variant of β fibrinogen is a genetic risk factor for coronary artery disease and myocardial infarction
78. A common mutation (G-455 A) in the β-fibrinogen promoter is an independent predictor of plasma fibrinogen, but not of ischemic heart disease. A study of 9,127 individuals based on the Copenhagen City Heart Study
79. Array-based multiplex analysis of candidate genes reveals two independent and additive genetic risk factors for myocardial infarction in the Finnish population
80. A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis
81. PIA1/A2 polymorphism of platelet glycoprotein IIIa and risks of myocardial infarction, stroke, and venous thrombosis
82. The relationship between polymorphisms in the endothelial cell nitric oxide synthase gene and the platelet GPIIIa gene with myocardial infarction and venous thromboembolism in African Americans
83. E-selectin polymorphism and atherosclerosis: An association study
84. DNA polymorphisms in adhesion molecule genes-A new risk factor for early atherosclerosis
85. Mortality rates among carriers of ataxia-telangiectasia mutant alleles
86. Polymorphisms at the Werner locus: II. 1074Leu/Phe, 1367Cys/Arg, longevity, and atherosclerosis
87. Genetic variation in alcohol dehydrogenase and the beneficial effect of moderate alcohol consumption on myocardial infarction
88. A common variant of the AMPD1 gene predicts improved cardiovascular survival in patients with coronary artery disease
89. Linkage and association of adrenergic and dopamine receptor genes in the distal portion of the long arm of chromosome 5 with systolic blood pressure variation
90. Evidence for single gene contributions to hypertension and lipid disturbances: Definition, genetics, and clinical significance
91. Activating mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy
92. Human renin gene BgII dimorphism associated with hypertension in two independent populations
93. Identification of a three-amino acid deletion in the alpha-2B-adrenergic receptor that is associated with reduced basal metabolic rate in obese subjects
94. Human beta-2 adrenoceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function
95. Lack of association between the trp64arg mutation in the beta-3-adrenergic receptor gene and obesity in Japanese men: A longitudinal analysis
96. A paired sibling analysis of the beta-3 adrenergic receptor and obesity in Mexican Americans
97. Phenotypes in three pedigrees with autosomal dominant obesity caused by haploinsufficiency mutations in the melanocortin-4 receptor gene
98. Obesity associated with a mutation in a genetic regulator of adipocyte differentiation
99. Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima Indians
100. Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
101. A variation at position -30 of the beta-cell glucokinase gene promoter is associated with reduced beta-cell function in middle-aged Japanese-American men
102. Mutant insulin syndromes
103. Prevalence of variants in candidate genes for type 2 diabetes mellitus in the Netherlands: The Rotterdam study and the Hoorn study
104. Association of a variant in exon 31 of the sulfonylurea receptor 1 (SUR1) gene with type 2 diabetes mellitus in French Caucasians
105. The common PPAR gamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
106. Genetic susceptibility to thrombosis and its relationship to physiological risk factors: The GAIT Study
107. Two loci on chromosomes 2 and X for premature coronary heart disease identified in early- and late-settlement populations of Finland
108. Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice
109. Genome-wide linkage analyses of systolic blood pressure using highly discordant siblings
110. Positional genomic analysis identifies the beta-adrenergic receptor gene as a susceptibility locus for human hypertension
111. Genomewide search for type 2 diabetes-susceptibility genes in French Whites: Evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24
112. The Finland-United States investigation of non-insulin dependent diabetes mellitus genetics (FUSION) study. I. An autosomal genome scan for genes that predispose to type 2 diabetes
113. The Finland-United States Investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. II. An autosomal genome scan for diabetes-related quantitative-trait loci
114. Report of an NHLBI working group
115. The genetics of serum lipid responsiveness to dietary interventions
116. Attenuated hypercholesterolemic response to a high-cholesterol diet in subjects heterozygous for the apolipoprotein A-IV-2 allele
117. Individual cholesterol variation in response to a margarine- or butter-based diet
118. Family history: A comprehensive genetic risk assessment method for the chronic conditions of adulthood
119. Role of insulin resistance in human disease
120. Reliability of reported family history of myocardial infarction
121. Accuracy of proband reported family history: The NHLBI Family Heart Study (FHS)
122. Accuracy of reported family history of diabetes mellitus. Results from San Luis Valley Diabetes Study
123. Summary of the second report of the National Cholesterol Education Program (NCEP) expert panel on detection evaluation treatment of high blood cholesterol in adults (Adult Treatment Panel II)
124. Beneficial effects of combined colestipol-niacin therapy on coronary atherosclerosis and coronary venous bypass grafts
125. Coronary angiographic changes with lovastatin therapy: The Monitored Atherosclerosis Regression Study (MARS)
126. Regression of coronary artery disease as a result of intensive lipid lowering therapy in men with high levels of apolipoprotein B
127. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
128. Effects of lipid lowering by pravastatin on progression and regression of coronary artery disease in symptomatic men with normal to moderately elevated serum cholesterol levels: The Regression Growth Evaluation Statin Study (REGRESS)
129. Effect of simvastatin on coronary atheroma: The Multicentre Anti-Atheroma Study (MAAS)
130. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
131. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: Results of AFCAPS/TexCAPS
132. Cholesterol-lowering and coronary atherosclerosis: Good news and bad news
133. "The lower the better" in hypercholesterolemia therapy: A reliable clinical guideline?
134. Cost and health implications of cholesterol lowering
135. Should we be measuring blood cholesterol levels in young adults?
136. Should there be a moratorium on the use of cholesterol lowering drugs?
137. Doubts about clinical impact of cholesterol reduction
138. Primary prevention of coronary heart disease in the Federal Republic of Germany. Analysis of cost-effectiveness
139. Familial lipoprotein disorders in patients with premature coronary artery disease
140. Managed care, managing uncertainty
141. The role of vitamins in the pathogenesis and treatment of hyperhomocysteinemia
142. Folic acid- an innocuous means to reduce plasma homocysteine
143. Impaired homocysteine metabolism in early-onset cerebral and peripheral occlusive arterial disease. Effects of pyridoxine and folic acid treatment
144. Oral estrogen improves serum lipids, homocysteine and fibrinolysis in elderly men
145. Testosterone decreases lipoprotein(a) in men
146. Levels of lipoprotein(a) decline with neomycin and niacin treatment
147. Comparison of the effects of diets enriched in lauric, palmitic, or oleic acids on serum lipids and lipoproteins in healthy women and men
148. Lipoprotein(a) excess and coronary heart disease
149. Influence of fitness status on very-low density lipoproteins subfractions and lipoprotein(a) in men and women
150. Effect of postmenopausal hormone therapy on lipoprotein(a) concentration
151. Coronary artery calcium area by electron-beam computed tomography and coronary atherosclerosis plaque area: A histopathologic correlation study
152. Comparison of electronbeam computed tomography and intracoronary ultrasound in detecting calcified and noncalcified plaques in patients with acute coronary syndromes and no or minimal to moderate angiographic coronary artery disease
153. Ultrafast computed tomography as a diagnostic modality in the detection of coronary artery disease: A multicenter study
154. Probabilistic model for prediction of angiographically defined obstructive coronary artery disease using electron beam computed tomography calcium score strata
155. Electron-beam computed tomography in the diagnosis of coronary artery disease
156. Predictive value of electron beam computed tomography of the coronary arteries: 19-Month follow-up of 1173 asymptomatic subjects
157. Electron beam computed tomographic coronary calcium as a predictor of coronary events: Comparison of two protocols
158. Identification of patients at increased risk of first unheralded acute myocardial infarction by electron-beam computed tomography
159. Prognostic value of coronary calcification and angiographic stenosis in patients undergoing coronary arteriography
160. Severity of coronary artery calcification by electron beam tomography predicts silent myocardial ischemia
161. Genetic counseling
162. Predisposition genetic testing for late-onset disorders in adults. A position paper of the National Society of Genetic Counselors
163. Statement on informed consent for genetic research
164. Genetic testing for susceptibility to adult-onset cancer. The process and content of informed consent
165. Statement on use of DNA testing for presymptomatic identification of cancer risk
166. Cardiovascular risk factors and health knowledge among freshemen college students with a family history of cardiovascular disease
167. The effect of genetic risk information and health risk assessment on compliance with preventive behaviors
168. BRCA1 testing in families with hereditary breast-ovarian cancer. A prospective study of patient decision making and outcomes
169. Psychological responses to BRCA1 mutation testing
170. Genetic discrimination and health insurance: An urgent need for reform
171. Genetic information and the workplace: Legislative approaches and policy changes
172. Discrimination as a consequence of genetic testing
173. Individual, family, and societal dimensions of genetic discrimination: A case study analysis
174. Genetic risk assessment and insurance
175. Laws that regulate the use of genetic information