Association of a variant in exon 31 of the sulfonylurea receptor 1 (SUR1) gene with type 2 diabetes mellitus in French Caucasians

Human Genetics

Volumn 107, Issue 2, 2000, Pages 138-144

  Reis, André F ^a   Ye, Wei Zhen ^a   Dubois Laforgue, Danièle ^b   Bellanné Chantelot, Christine ^c   Timsit, José ^b   Velho, Gilberto ^a  

^a HÔPITAL SAINT VINCENT DE PAUL   (France)

^b HÔPITAL NECKER ENFANTS MALADES   (France)

^c FONDATION JEAN DAUSSET CEPH   (France)

Author keywords

[No Author keywords available]

Indexed keywords

SULFONYLUREA RECEPTOR;

ADULT; AGED; ARTICLE; CAUCASIAN; CONTROLLED STUDY; DISEASE ASSOCIATION; EXON; FEMALE; FRANCE; GENE FREQUENCY; GENETIC VARIABILITY; HUMAN; HYPERTENSION; INSULIN RELEASE; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; ONSET AGE; PRIORITY JOURNAL; REGULATORY MECHANISM; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 0033812146     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004390000345     Document Type: Article

References (30)

1. Cloning of the beta cell high-affinity sulfonylurea receptor: A regulator of insulin secretion
2. + channels and insulin secretion: Their role in health and disease
3. + channel in pancreatic beta cells
4. Disease associations: Chance, artifact, or susceptibility genes?
5. Pathogenesis of type 2 diabetes: Metabolic and molecular implications for identifying diabetes genes
6. Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans
7. + channels: Generating excitement in pancreatic b-cells
8. Insulin resistance versus insulin deficiency in non-insulin-dependent diabetes mellitus: Problems and prospects
9. Insulin resistance and hypersecretion in obesity
10. Variant in sulfonylurea receptor-1 gene is associated with high insulin concentrations in non-diabetic Mexican Americans: SUR-1 gene variant and hyperinsulinemia
11. Genetic studies of the sulfonylurea receptor gene locus in NIDDM and in morbid obesity among French Caucasians
12. + channel gene (KIR6.2/BIR): A meta-analysis suggest a role in the polygenic basis of type II diabetes mellitus in Caucasians
13. Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene
14. Reduced beta-cell function and blood pressure in carriers of intron 16-3t variant of the sulfonylurea receptor gene
15. Variants in the sulfonylurea receptor gene: Association of the exon 16-3t variant with type II diabetes mellitus in Dutch Caucasians
16. What association analysis can and cannot tell us about the genetics of complex disease
17. Reconstitution of IKATP: An inward rectifier subunit plus the sulfonylurea receptor
18. Sequence variants in the sulfonylurea receptor (SUR) gene are associated with NIDDM in Caucasians
19. + channel and linkage studies with NIDDM in Japanese
20. Early-onset type 2 diabetes vs maturity onset diabetes of the youth: Evidence for the existence of two discrete diabetic syndromes
21. Identification and functional analysis of sulfonylurea receptor 1 variants in Japanese patients with NIDDM
22. Sulfonylurea receptor-1 gene variants are associated with gestational diabetes and type 2 diabetes but not with altered secretion of insulin
23. Emerging epidemic of type 2 diabetes in youth
24. Linkage studies in NIDDM with markers near the sulphonylurea receptor gene
25. Mutation of the pancreatic islet inward rectifier kir6.2 also leads to familial persistent hyperinsulinemic hypoglycemia of infancy
26. Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy
27. The genetic determinants of NIDDM: Strategies and recent results
28. Time of onset of non-insulin-dependent diabetes mellitus and genetic variation in the beta(3)-adrenergic-receptor gene
29. A susceptibility locus for early-onset non-insulin dependent (type 2) diabetes mellitus maps to chromosome 20q, proximal to the phosphoenolpyruvate carboxykinase gene