Expression of cytochrome P450 2E1 in normal human bronchial epithelial cells and activation by ethanol in culture

Archives of Toxicology

Volumn 75, Issue 6, 2001, Pages 335-345

  Runge, Dorothee M ^a,d   Stock, Thomas W ^a   Lehmann, Thomas ^a   Taege, Christiane ^a   Bernauer, Ulrike ^b   Stolz, Donna Beer ^c   Hofmann, Stefan ^a   Foth, Heidi ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b Fed Inst Hlth Protect Consumers   (Germany)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d Ingenium Pharmaceuticals AG   (Germany)

Author keywords

Activation; Chlorzoxazone; CYP2E1; Ethanol; Expression; Human bronchial cell culture

Indexed keywords

ALCOHOL; CARCINOGEN; CHLORZOXAZONE; CYTOCHROME P450 2B7; CYTOCHROME P450 2E1; CYTOCHROME P450 2F1; CYTOCHROME P450 ISOENZYME; MESSENGER RNA; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BRONCHUS MUCOSA; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROXYLATION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INHALATION; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSMISSION ELECTRON MICROSCOPY; XENOBIOTIC METABOLISM;

AGED; BLOTTING, WESTERN; BRONCHI; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; CYTOCHROME P-450 CYP2E1; ENZYME ACTIVATION; EPITHELIAL CELLS; ETHANOL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; RESPIRATORY MUCOSA; RNA, MESSENGER; TIME FACTORS;

BRONCHUS;

EID: 0034885904     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040100248     Document Type: Article

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