Effect of nicotine or cotinine on metabolism of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in isolated rat lung and liver

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 357, Issue 3, 1998, Pages 344-350

  Schulze, Johannes ^a   Schrader, Eberhard ^b   Foth, Heidi ^c   Kahl, Georg F ^b   Richter, Elmar ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Clotinine; Liver; Lung; Metabolism; Nicotine; NNK; Perfusion; Starvation

Indexed keywords

ALKALOID; CARCINOGEN; CIGARETTE SMOKE; COTININE; CYTOCHROME P450; NICOTINE; NITROSAMINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CIGARETTE SMOKING; CONTROLLED STUDY; HALF LIFE TIME; LIVER PERFUSION; METABOLIC ACTIVATION; METABOLITE; MOUSE; NONHUMAN; RAT; STARVATION; TOBACCO; TOXICOKINETICS; XENOBIOTIC METABOLISM;

ANIMALS; CARCINOGENS; COTININE; LIVER; LUNG; MALE; METABOLIC CLEARANCE RATE; NICOTINE; NICOTINIC AGONISTS; NITROSAMINES; PERFUSION; RATS; RATS, INBRED F344; RATS, SPRAGUE-DAWLEY; STARVATION;

EID: 0031938003     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00005177     Document Type: Article

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