The Saccharomyces cerevisiae aldose reductase is implied in the metabolism of methylglyoxal in response to stress conditions

Current Genetics

Volumn 39, Issue 5-6, 2001, Pages 273-283

  Aguilera, J ^a   Prieto, J A ^a  

^a INSTITUTO DE AGROQUÍMICA Y TECNOLOGÍA DE ALIMENTOS CSIC   (Spain)

Author keywords

Aldose reductase; Methylglyoxal; Stress; Yeast

Indexed keywords

ALDEHYDE REDUCTASE; CARBON; GLYOXALASE; HYDROGEN PEROXIDE; METHYLGLYOXAL; SODIUM CHLORIDE; SORBITOL;

ARTICLE; CELL LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME SUBSTRATE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; IN VITRO STUDY; IN VIVO STUDY; METABOLISM; MUTANT; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; STARVATION; STRESS; TEMPERATURE;

ALDEHYDE REDUCTASE; DNA PRIMERS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, FUNGAL; GENOTYPE; PLASMIDS; POLYMERASE CHAIN REACTION; PYRUVALDEHYDE; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE;

EID: 0034875879     PISSN: 01728083     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002940100213     Document Type: Article

References (55)

1. Accumulation of α-oxaldehydes during oxidative stress: A role in cytotoxicity
2. Assay of gluthatione, glutathione disulfide, and glutathione mixed disulfides in biological samples
3. GPD1, which encodes glycerol-3-phosphate dehydrogenase, is essential for growth under osmotic stress in Saccharomyces cerevisiae, and its expression is regulated by the high-osmolarity glycerol response pathway
4. Physiology of osmotolerance in fungi
5. An osmosensing signal transduction pathway in yeast
6. Advanced protein glycosylation in diabetes and aging
7. Osmotic regulation of gene expression
8. Active site modification of aldose reductase by nitric oxide donors
9. Method for determination of free intracellular and extracellular methylglyoxal in animal cells grown in culture
10. Methylglyoxal assay in cells as 2-methylquinoxaline using 1,2-diaminobenzene as derivatizing reagent
11. Stress-controlled transcription factors, stress-induced genes and stress tolerance in budding yeast
12. Two homologous zinc finger genes identified by multicopy suppression in a SNF1 protein kinase mutant of Saccharomyces cerevisiae
13. Methylglyoxal production in bacteria: Suicide or survival?
14. ORE, a eukaryotic minimal essential osmotic response element. The aldose reductase gene in hyperosmotic stress
15. Three genes whose expression is induced by stress in Saccharomyces cerevisiae
16. Renal medullary organic osmolytes
17. Genomic expression programs in the response of yeast cells to environmental changes
18. New yeast-Escherichia coli shuttle vectors constructed with in vivo mutagenized yeast genes lacking six base pair restriction enzymes
19. Isolation and properties of lens aldose reductase
20. Methylglyoxal and regulation of its metabolism in microorganisms
21. Expression of the Glyoxalase I gene of Saccharomyces cerevisiae is regulated by high osmolarity glycerol mitogen-activated protein kinase pathway in osmotic stress response
22. Transformation of intact yeast cells treated with alkali cations
23. Methylglyoxal toxicity in mammalian
24. Methylglyoxal in living organisms: Chemistry, biochemistry, toxicology and biological implications
25. Identification of cis and trans components of a novel heat shock stress regulatory pathway in Saccharomyces cerevisiae
26. Purification and partial characterization of an aldo-keto reductase from Saccharomyces cerevisiae
27. Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens
28. Protein measurement with the Folin-phenol reagent
29. Sudden depletion of carbon source blocks translation, but not transcription, in the yeast Saccharomyces cerevisiae
30. The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE)
31. MIPS: A database for protein sequences, homology data and yeast genome information
32. Expression of LIP1 and LIP2 genes from Geotrichum species in baker's yeast strains and their application to the bread-making process
33. Characterization of methylglyoxal synthase in Saccharomyces cerevisiae
34. Metabolism of 2-oxoaldehyde in yeasts. Purification and characterization of NADPH-dependent methylglyoxal-reducing enzyme from Saccharomyces cerevisiae
35. Different signaling pathways contribute to the control of GPD1 gene expression by osmotic stress in Saccharomyces cerevisiae
36. Osmotic stress-induced gene expression in Saccharomyces cerevisiae requires Msn1p and the novel nuclear factor Hot1p
37. The transcriptional response of Saccharomyces cerevisiae to osmotic shock: Hot1p and Msn2p/Msn4p are required for the induction of subsets of high osmolarity glycerol pathway-dependent genes
38. Mechanism for the formation of methylglyoxal from triosephosphates
39. Coordinated response of aldose reductase and sorbitol dehydrogenase regulates net sorbitol production in the rat renal inner medulla
40. Heat shock element architecture is an important determinant in the temperature and transactivation domain requirements for heat shock transcription factor
41. The HOG pathway controls osmotic regulation of transcription via the stress response element (STRE) of the Saccharomyces cerevisiae CTT1 gene
42. Roles of sugar alcohols in osmotic stress adaptation. Replacement of glycerol by mannitol and sorbitol in yeast
43. Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis
44. Kidney aldose reductase gene transcription is osmotically regulated
45. Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation
46. Heat shock factor and heat shock response
47. Heat shock transcription factor activates yeast metallothionein gene expression in response to heat and glucose starvation via distinct signalling pathways
48. Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae
49. Elevated recombination rates in transcriptionally active DNA
50. Reduction of trioses by NADPH-dependent aldo-keto reductases
51. New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae
52. Enzymology of carbonyl metabolism: Aldehyde dehydrogenase, aldo/keto reductase and alcohol dehydrogenase
53. Isolation of the gene encoding the Saccharomyces cerevisiae heat shock transcription factor
54. Regulation of genes encoding subunits of the trehalose synthase complex in Saccharomyces cerevisiae: Novel variations of STRE-mediated transcription control?