The opioidergic system in the combined regulation of pain and immunity

Biology Bulletin

Volumn 28, Issue 3, 2001, Pages 280-292

  Zakharova, L A ^a   Vasilenko, A M ^b  

^a KOL TSOV INSTITUTE OF DEVELOPMENTAL BIOLOGY   (Russian Federation)

^b A I EVDOKIMOV MOSCOW STATE UNIVERSITY OF MEDICINE AND DENTISTRY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0034861112     PISSN: 10623590     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016696605484     Document Type: Article

References (112)

1. Perineural defect and peripheral opioid analgesia in inflammation
2. Opioids modulate interleukin-1 production and secretion by bone marrow macrophages
3. Conditioning with transcutaneous nerve stimulation reduces C fiber mediated axon reflex flare in human skin
4. Opiate analgesia: How central is a peripheral target?
5. Stress-induced suppression of natural killer cell cytotoxicity in the rat: A naltrexone-insensitive paradigm
6. Behavioral differences between artificially selected aggressive and nonaggressive mice: Response to apomorphine
7. β-Endorphin modulation of IL-1-induced IL-2 production
8. Increases in vocalization and motor reflex thresholds generated by the intrathecal administration of serotonin or norepinephrine
9. The differential contribution of spinopetal projections to increases in vocalization and motor reflex thresholds generated by the microinjection of morphine into the periaqueductal gray
10. Effects of naloxone opiate blockade on the immunomodulation induced by exercise in rats
11. Opioid peptides modulate production of interferon-γ by human mononuclear cells
12. Effects of opioids on murine antibody responses
13. Immune cell-derived beta-endorphin: Production, release, and control of inflammatory pain in rats
14. Naltrexone antagonizes the analgesic and immunosuppressive effects of morphine in mice
15. Effects of opioid peptides on immunomodulatory processes
16. Serotonin and norepinephrine uptake inhibiting activity of centrally acting analgesics: Structural determinants and role in antinociception
17. Immune response products alter CNS activity: Interferon modulates central opioid functions
18. Heritability of symptoms in an experimental model of neuropathic pain
19. Central acute pain mechanisms
20. The involvement of μ-, δ-, and κ-opioid receptors in regulation of the humoral immune response
21. Immunomodulating effect of met-enkephalin on different stages of lymphocyte proliferation induced by concanavalin A in vitro
22. Immunosuppression in the definitive hosts of the human parasite, schistosoma mansoni, by release of immunoreactive neuropeptides
23. The influence of new immunostimulator myelopid on active peptide level
24. Mouse strain differences in immunosuppression by opioids in vitro
25. Interleukin-1 potentiation of β-endorphin secretion and the dynamics of interleukin-1 internalization in pituitary cells
26. Structures of two myelopeptides affecting pain
27. A Mechanism of action for morphine-induced immunosuppression: Corticosterone mediates morphine-induced suppression of natural killer cell activity
28. Visceral nociception: Consequences, modulation, and future
29. Isolation and characterization of a hemoglobin-derived opioid peptide from the human pituitary gland
30. Both T cells and macrophages are targets of opioid-induced immunosuppression
31. Dynorphin, a preferential ligand for κ-opioid receptors is present in nerve fibers and immune cells within inflamed tissue of the rat
32. 2+ modulation in human B cell lines
33. Immunosuppression by morphine is mediated by central pathways
34. Electrical stimulation of the sciatic nerve alters neuropeptide content and lymphocyte migration in the subcutaneous tissue of the rat hindpaw
35. Enhancement of phagocytosis by dynorphin A in mouse peritoneal macrophages
36. Effects of a chronic inflammatory stress on levels of pro-opiomelanocortin-derived peptides in rat spleen and thymus
37. Physiological mechanisms of pain and analgesia
38. Neuropeptide receptors in developing and adult rat spinal cord: An in vitro quantitative autoradiography study of calcitonin gene-related peptide, neurokinins, mu-opioid, galanin, somatostatin, neurotensin, and vasoactive intestinal polypeptide receptors
39. Characterization of the murine mu-opioid receptor gene
40. Multiple opioid system involvement in the mediation of parasitic infection-induced analgesia
41. Induction of β-endorphin secretion by lymphocytes after subcutaneous administration of corticotropin releasing factor
42. Differential effects of β-endorphin on cAMP levels in human peripheral blood mononuclear cells
43. Interaction between endogenous opioids and IL-2 on PHA-stimulated human lymphocytes
44. Opiate-like peptides principally differing from enkephalins in their structure
45. Obligatory role of B cells and adherent accessory cells in the transfer of a defect in morphine-mediated antinociception in C57BL/6J/bg (Beige-J) mice
46. Opioid activities of human β-casomorphins
47. 1 opioid receptor binding and inhibition of adenylyl cyclase in guinea pig brain membranes
48. Studies on the role of enkephalinase in mechanisms of morphine and acupunctural analgesia
49. Modulation of mitogen-induced spleen cell proliferation and the antibody-forming cell response by β-endorphin in vivo
50. The kappa opioid receptor expressed on the mouse R1.1 thymoma cell line is coupled to adenylyl cyclase through a pertussis toxin-sensitive guanine nucleotide-binding regulatory protein
51. G-protein-coupled receptors: Regulatory role of receptor kinases and arrestin proteins
52. Peptides and the primary afferent nociceptor
53. Opioid receptor affinities of the blood-derived tetrapeptides hemorphin and cytochronin
54. Morphine-induced decreased in vivo antibody response
55. 2 peptide fragments
56. Met-enkephalin modulates stress-induced alterations of the immune response in mice
57. 2]deltorphin II in mice: Evidence for delta receptor subtypes
58. Endorphinergic modulation of immune function: Potent action of the dipeptide glycyl-L-glutamine
59. Cellular signaling in thymocyte apoptosis
60. Neurophysiological analysis of the central afferentation mechanisms under conditions of physiological and pathological pain
61. Opioid systems in the response to inflammatory pain: Sustained blockade suggests role of κ- but not μ-opioid receptors in the modulation of nociception, behavior, and pathology
62. The genetics of pain and pain inhibition
63. 2+ level in concanavalin A-activated mouse lymphocytes
64. Local upregulation of corticotropin releasing hormone and interleukin-1 receptors in rats with painful hindlimb inflammation
65. Analgesic effect of μ- and κ-opioid agonists in beige and CXBK mice
66. Opioid action on membrane ion channels
67. Axon reflex: New views in an old field
68. The beta-endorphin inhibition of mitogen-induced splenocyte proliferation is mediated by central and peripheral paracrine-autocrine effects of opioid
69. The central questions in pain perception may be peripheral
70. Different μ receptor subtypes mediate spinal and supraspinal analgesia in mice
71. Physiological stress and immune response: Myelopeptides
72. CD19 monoclonal antibody HD37 inhibits anti-immunoglobulin-induced B-cell activation and proliferation
73. Ability of δ-opioid receptors to interact with multiple G-proteins is independent of receptor density
74. Gene expression and localization of opioid peptides in immune cells of inflamed tissue: Functional role in antinociception
75. Modulation of humoral immune response by central administration of leu-enkephalin: Effects of μ-, δ-, and κ-opioid receptor antagonists
76. The combined immunological and antinociceptive defects of the beige mice: The possible existence of A "μ-repressin,"
77. Molecular biology of opioid receptors
78. Cortical control of antinociceptive structures in reflectory analgesia
79. Interferon-gamma receptors in nociceptive pathways: Role in neuropathic pain-related behaviour
80. Positive and negative immunomodulation by opioid peptides
81. 3H]morphine binding to interleukin-1-activated thymocytes
82. Antinociceptive and immunosuppressive effects of opiate drugs: A structure-related activity study
83. Expression of corticotropin-releasing factor in inflamed tissue is required for intrinsic peripheral opioid analgesia
84. Corticotropin-releasing factor in antinociception and inflammation
85. Morphine suppresses the alloantigen-driven CTL response in a dose-dependent and naltrexone-reversible manner
86. m CTPase studies
87. Dual signal transduction through delta opioid receptors in a transfected human T-cell line
88. Analysis of new opioid-like peptides by a radioreceptor method
89. Analgesic and immunomodulatory effects of codeine and codeine 6-glucuronide
90. Peripheral opioid receptors
91. Multiphasic effect of morphine on the release of substance P from rat trigeminal nucleus slices
92. κ- and δ-opioids block sympathetically dependent hyperalgesia
93. A novel analgetic dipeptide from bovine brain is a possible met-enkephalin releaser
94. Immunomodulatory activity of μ- and κ-selective opioid agonists
95. Altered hematopoiesis, behaviour, and sexual function in μ-opioid receptor-deficient mice
96. Regulation of multiple effects by the cloned δ-opioid receptor: Stimulation of phospholipase C and type II adenylyl cyclase
97. 2+ concentration in human lymphocytes
98. 2 receptors
99. Interrelationship of pain sensitivity and immune response in mice: Changes in pain threshold, antibody production, and ratio of μ, δ, and κ types of opioid receptors on spleen cells caused by hot plate test
100. Immune activation: The role of pro-inflammatory cytokines in inflammation, illness responses, and pathological pain states
101. Induction of interleukin-1β mRNA in the hypothalamus following subcutaneous injection of formalin into the rat hind paw
102. Adenosine and opiate-like substances mediate antinociception at the spinal cord
103. Morphine inhibits spontaneous and cytokine-enhanced natural killer cell cytotoxicity in volunteers
104. Behavioral effects of lipopolysaccharide in rats: Involvement of endogenous opioids
105. κ-opioid receptor modulation of the release of substance P in the dorsal horn
106. Neuropharmacology of opiates and opioids
107. Involvement of opioid receptors in met-enkephalin modulation of blast-transformation of mouse splenocytes
108. Participation of opioids in the immunostimulatory activity of myelopeptides
109. Hypoalgesia induced by a weak stress-inducing action is accompanied by a decreased antibody production and changes in the type of opioid receptors on immunocompetent cells