Kappa-opioid receptor modulation of the release of substance P in the dorsal horn

Brain Research

Volumn 706, Issue 1, 1996, Pages 80-88

  Zachariou, Venetia ^a   Goldstein, Barry D ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Antinociception; Dynorphin(1 8); Nociception; Spinal cord; Tachykinin; Thermal stimulation

Indexed keywords

DYNORPHIN[1-8]; KAPPA OPIATE RECEPTOR; NORBINALTORPHIMINE; OPIATE ANTAGONIST; SUBSTANCE P; TACHYKININ;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; HORMONE RELEASE; MALE; NOCICEPTION; NONHUMAN; PERFUSION; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; SPINAL CORD DORSAL HORN;

EID: 0030071401     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(95)01182-X     Document Type: Article

References (47)

1. Besse D., Lombard, M.C. and Besson, J.M., Autoradiographic distribution of μ, δ, κ opiate binding sites in the superficial dorsal horn of the rostrocaudal axis of the rat spinal cord, Brain Res., 548 (1991) 287-291.
2. Brodin, E., Linderoth, B., Gazelius, B. and Ungerstedt, U., In vivo release of Substance P in cat dorsal horn studied with microdialysis, Neurosci. Lett., 76 (1987) 357-362.
3. Calcagnetti, D.J., Helmstetter, F.D. and Fanselow, M.S., Analgesia produced by centrally administered DAGO, DPDPH and U50488H in the formalin test. Eur. J. Pharmacol., 153 (1988) 117-122.
4. Chang, M.M. and Leeman, S.E., Isolation of a sialogonic peptide from bovine hypothalamic tissue and its characterization as Substance P, J. Biol. Chem., 245 (1970) 4784-4790.
5. Chien, C.C., Brown, G., Pan, Y.X. and Pasternak, G W., Blockade of U50,488H analgesia by antisence oligonucleotides to a κ-opioid receptor, Eur. J. Pharmacol., 253 (1994) R7-R8.
6. Collin, E., Maubirgne, A., Bourgoin S., Chantrel, D., Hamon, M. and Cesselin F., In vivo tonic inhibition of spinal substance P (-like material) release by endogenous opioids acting at δ-receptors, Neuroscience, 44 (1991) 725-731.
7. Collin, E., Mauborgne, A., Bourgoin, S., Mantelet, S., Ferhat, L., Hamon, M. and Cesselin, F., Kappa-/Mu-receptor interactions in the opioid control of the in vivo release of Substance P-like material from the rat spinal cord, Neuroscience, 51 (1992) 347-355.
8. Corbett, A.D., Paterson, S.J., McKnight, A.T., Mangan, J. and Kosterlitz, H.W., Dynorphin 1-8 and Dynorphin 1-9 are ligands for the κ-subtype of opiate receptor, Nature, 299 (1982) 79-81.
9. Dixon, D.M. and Traynor, J.R., Formation of [Leu] Enkephalin from Dynorphin A(1-8) by rat spinal cord in Vitro, Br. J. Pharmacol., 91 (1987) 300P.
10. Duggan, A.W., Morton, R., Zhao, Z.Q. and Hendry, I.A., Noxious heating of the skin releases immunoreactive substance P in the substantia gelatinosa of the cat: a study with antibody microprobes, Brain Res., 403 (1987) 345-349.
11. Duggan, A.W., Hendry, I.A., Morton, C.R., Hutchison, W.D. and Zhao, Z.Q., Cutaneous stimuli releasing immunoreactive substance P in the dorsal horn of the cat, Brain Res., 451 (1988) 261-273.
12. Fields, H.L., Emson, P.C., Leigh, B.K., Gilbert, R.F.T. and Iversen, L.L.. Multiple opiate receptor sites on primary afferent fibers, Nature, 284 (1980) 351-353.
13. Gouarderes, C., Kopp, N., Cross, J. and Quirion, D., Kappa opioid receptors in human lumbro-sacral spinal cord, Brain Res. Bull., 16 (1986) 355-361.
14. Hayes, A.G. Sheehan, M.J. and Tyers, M.B., Differential sensitivity of models of antinociception in the rat, mouse and guinea-pig to μ-and κ-opioid receptor agonists, Br. J. Pharmacol., 91 (1987) 823-832.
15. Henry, J.L., Effects of substance P on functionally identified units in cat spinal cord, Brain Res., 114 (1976) 439-451.
16. Hokfelt, T., Kellerth, J.O., Nilsson, G. and Pernow, B., Experimental immunohistochemical studies on the localization and distribution of substance P in cat primary sensory neurons, Brain Res., 100 (1975) 235-252.
17. Hollt, V., Harmann, I., Millan, M.J. and Herz, A., Prodynorphin gene expression is enhanced in the spinal cord of chronic arthritic rats, Neurosci. Lett., 73 (1987) 90-94.
18. Hunt S.P., Kelly J.S. and Emson, P.C., The electron microscopic localization of methionine-enkephalin within the superficial layers (I and II) of the spinal cord, Neuroscience, 5 (1980) 1871-1890.
19. Hylden, J.L.K. and Wilcox, G.L., Intrathecal substance P elicits a caudally-directed biting and scratching behavior in mice, Brain Res., 217 (1981) 212-215.
20. Iadarola, M.J., Brady, L.S., Draisci, D. and Dubner, D., Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: stimulus specificity, behavioral parameters and opioid receptor binding, Pain, 35 (1988) 313-326.
21. Jessel, T.M., Iversen, L.L. and Cuello, A.C., Capsaicin-induced depletion of Substance P from primary sensory neurones, Brain Res., 152 (1978) 183-188.
22. Jessel, T., Tsunoo, A., Kanazawa, I. and Otsuka, M., Substance P: depletion in the dorsal horn of rat spinal cord after section of the peripheral processes of primary sensory neurons, Brain Res., 168 (1979) 247-259.
23. Jhamandas, K. and Sutak, M., Comparative spinal analgesic action of dynorphin(1-8), dynorphin(1-9), dynorphin(1-13) and a kappa receptor agonist, U50,488H, Can. J. Physiol. Pharmacol., 64 (1986) 263-268.
24. Kajander, K.C., Sahara, Y., Iadarola, M.J. and Bennett, G.J., Dynorphin increases in the dorsal spinal cord in rats with a painful peripheral neuropathy, Peptides, 11 (1990) 719-728.
25. Kuraishi, Y., Hirota, N., Sato, Y., Hino, Y., Satoh, M. and Takagi, H., Evidence that Substance P and somatostatin transmit separate information related to pain in the spinal dorsal horn, Brain Res., 325 (1985) 294-298.
26. Kuraishi, Y., Hirota, N., Sato, Y., Hanashima, N., Takagi, H. and Satoh, M., Stimulus specificity of peripherally evoked Substance P release from the rabbit dorsal horn in situ, Neuroscience, 30 (1989) 241-250.
27. Liang, V., Go, W. and Yaksh, T., Release of SP from the cat spinal cord, J. Physiol., 391 (1987) 141-167.
28. McCarson, K. and Goldstein, B.D., Release of SP into the superficial dorsal horn following nociceptive activation of the hindpaw of the rat, Brain Res., 568 (1991) 109-115.
29. Millan, M.J., Kappa-opioid receptor-mediated antinociception in the rat. I. Comparative actions of mu and kappa-opioids against noxious thermal, pressure and electrical stimuli, J. Pharmacol. Exp. Ther., 251 (1989) 334-341.
30. Millan, M.J., Czonkowski, A., Lipkowski, A. and Herz, A., Kappaopioid receptor-mediated antinociception in the rat. II. Supraspinal in addition to spinal sites of action, J. Pharmacol. Exp. Ther., 251 (1989) 342-350.
31. Millan, M.J., κ-opioid receptors and analgesia, Trends Pharmacol. Sci., 11 (1990) 70-76.
32. Morton, C.R., Hutchison, W.D., Hendry, I.A. and Duggan, A.W., Somatostatin: evidence for a role in thermal nociception, Brain Res., 488 (1989) 89-96.
33. Nakazawa, T., Furua, Y., Kaneko, T. and Yamatsu, K., Spinal kappa receptor mediated analgesia of E-2078, a systemically active dynorphin analog, in mice, J. Pharmacol. Exp. Ther., 256 (1991) 76-81.
34. Numata, H., Hiranuma, T. and Oka, T., Inactivation of Dynorphin-(1-8) in isolated preparations by three peptidases, Jap. J. Pharmacol, 47 (1988) 417-423.
35. Oku, R., Satoh, M. and Takagi, H., Release of Substance P from the spinal dorsal horn is enhanced in polyarthritic rats, Neurosci. Lett., 74 (1987) 315-319.
36. Otsuka, M. and Konishi S., Release of substance P-like immunoreactivity from isolated spinal cord of newborn rat, Nature, 265 (1976) 83-84.
37. Pelissier, T., Paeile, C., Soto-Moyano, R., Saavedra, H. and Hernandez, A., Analgesia produced by intrathecal administration of the κ-opioid agonist, U50,488H, on formalin-evoked cutaneous pain in the rat, Eur. J. Pharmacol., 190 (1990) 287-293.
38. Portoghese, P.S., Nagase, H., Lipkowski, A.W., Larson, D.L. and Takemori, A.E., Binaltorphimine-related bivalent ligands and their κ-opioid receptor antagonist selectivity, J. Med. Chem., 31 (1988) 836-841.
39. Ruda, M.A., Iadarola, M.J., Cohen, L.V. and Young, W.S., In situ hybridization histochemistry and immunocytochemistry reveal an increase in spinal dynorphin biosynthesis in a rat model of peripheral inflammation and hyperalgesia, Proc. Natl. Acad. Sci. USA, 85 (1988) 622-626.
40. Schmauss C. and Yaksh T.L., In vivo studies on spinal opiate receptor systems mediating antinociception. II. Pharmacological profiles suggesting a differential association of mu, delta and kappa receptors with visceral chemical and cutaneous thermal stimuli in the rat, J. Pharmacol Exp. Ther., 137 (1987) 197-205.
41. Takemori, A.E., Beghonia, Y.H., Naeseth, J. and Portighese, P.S., Nor-binaltorphimine, a highly selective kappa-opioid receptor antagonist in analgesic and receptor binding assays, J. Pharmacol, Exp. Ther., 257 (1988) 255-259.
42. Yaksh, T.L., Jessel, T.M., Gamse, R., Mudge, A.W. and Leeman, S.E., Intrathecal morphine inhibits Substance P release from mammalian spinal cord in vivo, Nature, 286 (1980) 155-157.
43. Yaksh, T., Opiate receptor systems and the endorphins: a review of their spinal organization, J. Neurosurg., 67 (1987) 156-176.
44. Yasphal, K., Wright, D.M. and Henry, J.L., Substance P reduces tail flick latency: implications for chronic pain syndromes, Pain, 14 (1982) 155-167.
45. Yashpal, K., Radhakrishnan, V., Coderre, T.J. and Henry, J.L., CP-96,345 but not its stereoisomer, CP-96,344, blocks the nociceptive responses to intrathecally administered Substance P and to noxious thermal and chemical stimuli in the rat, Neuroscience, 52 (1993) 1039-1047.
46. Yoshimura, M. and North, R.A., Substantia gelatinosa neurons hyperpolarized in vitro by enkephalin, Nature, 305 (1983) 529-530.
47. Zachariou, V. and Goldstein, B.D., Delta opioid receptor mediated control of SPLI release in the dorsal horn of the rat following mechanical or thermal noxious peripheral stimulation, Soc. Neurosci. Abstr., 20 (1994) 963.