Release of Toll-like receptor-2-activating bacterial lipoproteins in Shigella flexneri culture supernatants

Infection and Immunity

Volumn 69, Issue 10, 2001, Pages 6248-6255

  Aliprantis, A O ^a   Weiss, D S ^a   Radolf, J D ^a   Zychlinsky, A ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; LIPOPROTEIN; TOLL LIKE RECEPTOR 2;

ARTICLE; BACTERIUM CULTURE; CYTOTOXICITY; DIARRHEA; DYSENTERY; ENZYME ACTIVATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN SECRETION; SHIGELLA FLEXNERI; SHIGELLOSIS; SUPERNATANT;

APOPTOSIS; BACTERIAL PROTEINS; CELL LINE; CHEMICAL FRACTIONATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CULTURE MEDIA; DROSOPHILA PROTEINS; HUMANS; LIPID METABOLISM; LIPOPOLYSACCHARIDES; LIPOPROTEINS; MEMBRANE GLYCOPROTEINS; PHENOL; RECEPTORS, CELL SURFACE; SHIGA TOXIN; SHIGELLA FLEXNERI; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTORS; TRICHLOROACETIC ACID;

EID: 0034836911     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.10.6248-6255.2001     Document Type: Article

References (40)

1. Cell activation and apoptosis by bacterial lipoproteins through Toll-like receptor-2
2. The apoptotic signaling pathway activated by Toll-like receptor-2
3. Function and activation of NF-κB in the immune system
4. Fatty acids of Treponema pallidum and Borrelia burgdorferi lipoproteins
5. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors
6. A bacterial invasin induces macrophage apoptosis by directly binding ICE
7. Identification of outer membrane proteins, including known lymphocyte mitogens, as the endotoxin protein of Escherichia coli 0111
8. Bacterial modulins: A novel class of virulence factors which cause host tissue pathology by inducing cytokine synthesis
9. Inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2
10. Cutting edge: Repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2
11. Release of outer membrane fragments from normally growing Escherichia coli
12. Stimulation of human and murine adherent cells by bacterial lipoprotein and synthetic lipopeptide analogues
13. Global burden of Shigella infections: Implications for vaccine development and implementation of control strategies
14. Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products
15. Endotoxin-induced early gene expression in C3H/HeJ (Lpsd) macrophages
16. Genetic determinants of Shigella pathogenicity
17. Binding of polymyxin B to the lipid A portion of bacterial lipopolysaccharides
18. Isolation, structure elucidation, and synthesis of a macrophage stimulatory lipopeptide from Mycoplasma fermentans acting at picomolar concentration
19. Structure and specific activity of macrophage-stimulating lipopeptides from Mycoplasma hyorhinis
20. Lipoproteins of Borrelia burgdorferi and Treponema pallidum activate cachectin/tumor necrosis factor synthesis. Analysis using a CAT reporter construct
21. Synthesis and assembly of bacterial membrane components. A lipopolysaccharide-phospholipid-protein complex excreted by living bacteria
22. Shigella plays dangerous games
23. Infection of rabbit Peyer's patches by Shigella flexneri: Effect of adhesive or invasive bacterial phenotypes on follicle-associated epithelium
24. Shigella sonnei plasmids: Evidence that a large plasmid is necessary for virulence
25. Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytic cells via a CD14-dependent pathway distinct from that used by lipopolysaccharide
26. Borrelia burgdorferi upregulates expression of adhesion molecules on endothelial cells and promotes transendothelial migration of neutrophils in vitro
27. Endotoxin protein: A B-cell mitogen and polyclonal activator of C3H/HeJ lymphocytes
28. Toll-like receptor 4, but not toll-like receptor 2, is a signaling receptor for Escherichia and Salmonella lipopolysaccharides
29. Recognition of gram-negative bacteria and endotoxin by the innate immune system
30. Variable major lipoprotein is a principal TNF-inducing factor of louse-borne relapsing fever
31. The role of CD14 in signaling mediated by outer membrane lipoproteins of Borrelia burgdorferi
32. Biosynthesis of lipoproteins
33. A new ABC transporter mediating the detachment of lipid-modified proteins from membranes
34. Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling
35. IpaB mediates macrophage apoptosis induced by Shigella flexneri
36. Shigella flexneri induces apoptosis in infected macrophages
37. Perspectives series: Host/pathogen interactions, apoptosis in bacterial pathogenesis
38. In vivo apoptosis in Shigella flexneri infections