Variable major lipoprotein is a principal TNF-inducing factor of louse- borne relapsing fever

Nature Medicine

Volumn 4, Issue 12, 1998, Pages 1416-1420

  Vidal, Vincent ^a   Scragg, Ian G ^a   Cutler, Sally J ^b   Rockett, Kirk A ^a   Fekade, Daniel ^c   Warrell, David A ^a   Wright, David J M ^b   Kwiatkowski, Dominic ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c Black Lion Hospital   (Ethiopia)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOPROTEIN; TUMOR NECROSIS FACTOR;

ANTIBIOTIC THERAPY; ARTICLE; BORRELIA; BORRELIA INFECTION; CYTOKINE PRODUCTION; DISEASE SEVERITY; HERXHEIMER REACTION; HUMAN; HUMAN CELL; LOUSE; LYME DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION;

AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; BORRELIA; CELL LINE; DISEASE VECTORS; HUMANS; LICE; MOLECULAR SEQUENCE DATA; RELAPSING FEVER; SEQUENCE ALIGNMENT; TUMOR NECROSIS FACTOR-ALPHA;

BORRELIA HERMSII; BORRELIA RECURRENTIS; PHTHIRAPTERA;

EID: 0031757986     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/4007     Document Type: Article

References (27)

1. Johnson Jr., W.D. in Principles and Practice of Infectious Diseases, 4th ed. (eds. Mandell, G.L., Bennett, J.E. & Dolin, R.) 2141-2143 (Churchill Livingstone, New York, 1994).
2. Bryceson, A.D. Clinical pathology of the Jarisch-Herxheimer reaction. J. Infect. Dis. 133, 696-704 (1976).
3. Luger, S.W. et al. Comparison of cefuroxime axetil and doxycycline in treatment of patients with early Lyme disease associated with erythema migrans. Antimicrob. Agents Chemother. 39, 661-667 (1995).
4. Wright, D.J. Reaction following treatment of murine borreliosis and Shwartzman type reacion with borrelial sonicates. Parasite Immunol. 2, 201-221 (1980).
5. Negussie, Y. et al. Detection of plasma tumor necrosis factor, interleukins 6, and 8 during the Jarisch-Herxheimer Reaction of relapsing fever. J. Exp. Med. 175, 1207-1212 (1992).
6. Fekade, D. et al. Prevention of Jarisch-Herxheimer reactions by treatment with antibodies against tumor necrosis factor alpha. N. Engl. J. Med. 335, 311-315 (1996).
7. Takayama, K., Rothenberg, R.J. & Barbour, A.G. Absence of lipopolysaccharide in the Lyme disease spirochete, Borrelia burgdorferi. Infect. Immun. 55, 2311-2313 (1987).
8. Radolf, J.D. et al. Lipoproteins of Borrelia burgdorferi and Treponema pallidum activate cachectin/tumor necrosis factor synthesis. Analysis using a CAT reporter construct. J. Immunol. 147, 1968-1974 (1991).
9. Weis, J.J., Ma, Y. & Erdile, L.F. Biological activities of native and recombinant Borrelia burgdorferi outer surface protein A: dependence on lipid modification. Infect Immun. 62, 4632-4636 (1994).
10. Bouchon, B., Klein, M., Bischoff, R., Van Dorsselaer, A. & Roitsch, C. Analysis of the lipidated recombinant outer surface protein A from Borrelia burgdorferi by mass spectrometry. Anal. Biochem. 246, 52-61 (1997).
11. Braun, V. Covalent lipoprotein from the outer membrane of Escherichia coli. Biochim. Biophys. Acta 415, 335-377 (1975).
12. Fraser, C.M. et al. Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi. Nature 390, 580-586 (1997).
13. Cutler, S.J. et al. Borrelia recurrentis characterization and comparison with relapsing-fever, Lyme-associated, and other Borrelia spp. Int. J. Syst. Bacteriol. 47, 958-968 (1997).
14. Cutler, S.J. et al. Successful in-vitro cultivation of Borrelia recurrentis. Lancet 343,-242 (1994).
15. de Silva, A.M.D. & Fikrig, E. Borrelia burgdorferi genes selectively expressed in ticks and mammals. Parasitol. Today 13, 267-270 (1997).
16. de Silva, A.M. & Fikrig, E. Arthropod-and host-specific gene expression by Borrelia burgdorferi. J. Clin. Invest. 99, 377-379 (1997).
17. Schwan, T.G., Piesman, J., Golde, W.T., Dolan, M.C. & Rosa, P.A. Induction of an outer surface protein on Borrelia burgdorferi during tick feeding. Proc. Natl. Acad. Sci. USA 92, 2909-2913 (1995).
18. Montgomery, R.R., Malawista, S.E., Feen, K.J. & Bockenstedt, L.K. Direct demonstration of antigenic substitution of Borrelia burgdorferi ex vivo: exploration of the paradox of the early immune response to outer surface proteins A and C in Lyme disease. J. Exp. Med. 183, 261-269 (1996).
19. Barbour, A.C., Tessier, S.L. & Stoenner, H.G. Variable major proteins of Borrellia hermsii. J. Exp. Med. 156, 1312-1324 (1982).
20. Plasterk, R.H., Simon, M.I. & Barbour, A.G. Transposition of structural genes to an expression sequence on a linear plasmid causes antigenic variation in the bacterium Borrelia hermsii. Nature 318, 257-263 (1985).
21. Barbour, A.G. Antigenic variation of a relapsing fever Borrelia species. Annu. Rev. Microbiol. 44, 155-171 (1990).
22. Cadavid, D., Thomas, D.D., Crawley, R. & Barbour, A.G. Variability of a bacterial surface protein and disease expression in a possible mouse model of systemic Lyme borreliosis. J. Exp. Med. 179, 631-642 (1994).
23. Zhang, J.R., Hardham, J.M., Barbour, A.G. & Norris, S.J. Antigenic variation in Lyme disease borreliae by promiscuous recombination of VMP-like sequence cassettes. Cell 89, 275-285 (1997).
24. Pradines Figueres, A. & Raetz, C.R. Processing and secretion of tumor necrosis factor alpha in endotoxin-treated Mono Mac 6 cells are dependent on phorbol myristate acetate. J. Biol. Chem. 267, 23261-23268 (1992).
25. Allan, R.J., Rowe, A. & Kwiatkowski, D. Plasmodium falciparum varies in its ability to induce tumor necrosis factor. Infect. Immun. 61, 4772-4776 (1993).
26. Matsudaira, P. in A Practical Guide to Protein Purification for Microsequencing (Academic Press, London, 1993).
27. Barbour, A.G. & Garon, C.F. Linear plasmids of the bacterium Borrelia burgdorferi have covalently closed ends. Science 237, 409-411 (1987).