메뉴 건너뛰기




Volumn 185, Issue 11, 1997, Pages 1951-1958

Isolation, structure elucidation, and synthesis of a macrophage stimulatory lipopeptide from Mycoplasma fermentans acting at picomolar concentration

Author keywords

[No Author keywords available]

Indexed keywords

LIPOPEPTIDE; MACROPHAGE ACTIVATING FACTOR;

EID: 0345671672     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.185.11.1951     Document Type: Article
Times cited : (366)

References (52)
  • 1
    • 0024821510 scopus 로고
    • Interactions between mycoplasmas and the immune system
    • Ruuth, E., and F. Praz. 1989. Interactions between mycoplasmas and the immune system. Immunol. Rev. 112:133-160.
    • (1989) Immunol. Rev. , vol.112 , pp. 133-160
    • Ruuth, E.1    Praz, F.2
  • 2
    • 0025999831 scopus 로고
    • Involvement of interleukin-1 (IL-1), IL-6, IL-2, and IL-4 in generation of cytolytic T cells from thymocytes stimulated by a Mycoplasma fermentans-derived product
    • Mühlradt, P.F., H. Quentmeier, and E. Schmitt. 1991. Involvement of interleukin-1 (IL-1), IL-6, IL-2, and IL-4 in generation of cytolytic T cells from thymocytes stimulated by a Mycoplasma fermentans-derived product. Infect. Immun. 59: 3962-3968.
    • (1991) Infect. Immun. , vol.59 , pp. 3962-3968
    • Mühlradt, P.F.1    Quentmeier, H.2    Schmitt, E.3
  • 3
    • 0028030391 scopus 로고
    • Induced mouse spleen B-cell proliferation and secretion of immunoglobulin by lipid-associated membrane proteins of Mycoplasma fermentans incognitus and Mycoplasma penetrans
    • Feng, S.-H., and S.-C. Lo. 1994. Induced mouse spleen B-cell proliferation and secretion of immunoglobulin by lipid-associated membrane proteins of Mycoplasma fermentans incognitus and Mycoplasma penetrans. Infect. Immun. 62:3916-3921.
    • (1994) Infect. Immun. , vol.62 , pp. 3916-3921
    • Feng, S.-H.1    Lo, S.-C.2
  • 4
    • 0028001141 scopus 로고
    • Characterization and purification of a macrophage-triggering factor produced in Mycoplasma arginini-infected L5178Y cell cultures
    • Yang, G., F.D. Coffman, and E.F. Wheelock. 1994. Characterization and purification of a macrophage-triggering factor produced in Mycoplasma arginini-infected L5178Y cell cultures. J. Immunol. 153:2579-2591.
    • (1994) J. Immunol. , vol.153 , pp. 2579-2591
    • Yang, G.1    Coffman, F.D.2    Wheelock, E.F.3
  • 5
    • 0027305503 scopus 로고
    • Association of Mycoplasma genitalium with acute non-gonococcal urethritis
    • Horner, P.J., C.B. Gilroy, B.J. Thomas, R.O.M. Naidoo, and D. Taylor-Robinson. 1993. Association of Mycoplasma genitalium with acute non-gonococcal urethritis. Lancet. 342: 582-585.
    • (1993) Lancet , vol.342 , pp. 582-585
    • Horner, P.J.1    Gilroy, C.B.2    Thomas, B.J.3    Naidoo, R.O.M.4    Taylor-Robinson, D.5
  • 7
    • 0001439261 scopus 로고
    • Mycoplasma-induced arthritis
    • S. Razin and M.F. Barile, editors. Academic Press, Orlando
    • Cole, B.C., L.R. Washburn, and D. Taylor-Robinson. 1985. Mycoplasma-induced arthritis. In The Mycoplasmas. S. Razin and M.F. Barile, editors. Academic Press, Orlando. 107-160.
    • (1985) The Mycoplasmas , pp. 107-160
    • Cole, B.C.1    Washburn, L.R.2    Taylor-Robinson, D.3
  • 8
    • 0025777126 scopus 로고
    • Rheumatoid arthritis: New findings on the failure to isolate or detect mycoplasmas by multiple cultivation or serologic procedures and a review of the literature
    • Barile, M.F., H. Yoshida, and H. Roth. 1991. Rheumatoid arthritis: new findings on the failure to isolate or detect mycoplasmas by multiple cultivation or serologic procedures and a review of the literature. Rev. Infect. Dis. 13:571-582.
    • (1991) Rev. Infect. Dis. , vol.13 , pp. 571-582
    • Barile, M.F.1    Yoshida, H.2    Roth, H.3
  • 9
    • 0029921717 scopus 로고    scopus 로고
    • Mycoplasma fermentans in joints of patients with rheumatic arthritis and other joint disorders
    • Schaeverbeke, T., C.B. Gilroy, C. Bébéar, J. Dehais, and D. Taylor-Robinson. 1996. Mycoplasma fermentans in joints of patients with rheumatic arthritis and other joint disorders. Lancet. 347:1418.
    • (1996) Lancet , vol.347 , pp. 1418
    • Schaeverbeke, T.1    Gilroy, C.B.2    Bébéar, C.3    Dehais, J.4    Taylor-Robinson, D.5
  • 11
    • 0025718524 scopus 로고
    • Newly discovered mycoplasma isolated from patients infected with HIV
    • Lo, S.-C., M.M. Hayes, R.Y.-H. Wang, P.F. Pierce, H. Kotani, and J.W.K. Shih. 1991. Newly discovered mycoplasma isolated from patients infected with HIV. Lancet. 338:1415-1418.
    • (1991) Lancet , vol.338 , pp. 1415-1418
    • Lo, S.-C.1    Hayes, M.M.2    Wang, R.Y.-H.3    Pierce, P.F.4    Kotani, H.5    Shih, J.W.K.6
  • 12
    • 0029891985 scopus 로고    scopus 로고
    • Bacterial modulins: A novel class of virulence factors which cause host tissue pathology by inducing cytokine synthesis
    • Henderson, B., S. Poole, and M. Wilson. 1996. Bacterial modulins: a novel class of virulence factors which cause host tissue pathology by inducing cytokine synthesis. Microbiol. Rev. 60:316-341.
    • (1996) Microbiol. Rev. , vol.60 , pp. 316-341
    • Henderson, B.1    Poole, S.2    Wilson, M.3
  • 13
    • 0029805203 scopus 로고    scopus 로고
    • Host factors and the pathogenesis of HIV-induced disease
    • Fauci, A.S. 1996. Host factors and the pathogenesis of HIV-induced disease. Nature (Lond.). 384:529-534.
    • (1996) Nature (Lond.) , vol.384 , pp. 529-534
    • Fauci, A.S.1
  • 14
    • 0016733262 scopus 로고
    • The lipoprotein of the outer membrane of Escherichia coli: A B-lymphocyte mitogen
    • Melchers, F., V. Braun, and C. Galanos. 1975. The lipoprotein of the outer membrane of Escherichia coli: a B-lymphocyte mitogen. J. Exp. Med. 142:473-482.
    • (1975) J. Exp. Med. , vol.142 , pp. 473-482
    • Melchers, F.1    Braun, V.2    Galanos, C.3
  • 15
    • 0025193309 scopus 로고
    • Mycoplasma fermentans-derived high molecular weight material induces interleukin-6 release in cultures of murine macrophages and human monocytes
    • Quentmeier, H., E. Schmitt, H. Kirchhoff, W. Grote, and P.F. Mühlradt. 1990. Mycoplasma fermentans-derived high molecular weight material induces interleukin-6 release in cultures of murine macrophages and human monocytes. Infect. Immun. 58:1273-1280.
    • (1990) Infect. Immun. , vol.58 , pp. 1273-1280
    • Quentmeier, H.1    Schmitt, E.2    Kirchhoff, H.3    Grote, W.4    Mühlradt, P.F.5
  • 16
    • 0018103513 scopus 로고
    • Modulation of myelopoiesis by different bacterial cell-wall components: Induction of colony-stimulating activity (by pure preparations, low-molecular-weight degradation products, and a synthetic low-molecular analog of bacterial cell-wall components) in vitro
    • Staber, F.G., R.H. Gisler, G. Schumann, L. Tarcsay, E. Schläfli, and P. Dukor. 1978. Modulation of myelopoiesis by different bacterial cell-wall components: induction of colony-stimulating activity (by pure preparations, low-molecular-weight degradation products, and a synthetic low-molecular analog of bacterial cell-wall components) in vitro. Cell. Immunol. 37:174-187.
    • (1978) Cell. Immunol. , vol.37 , pp. 174-187
    • Staber, F.G.1    Gisler, R.H.2    Schumann, G.3    Tarcsay, L.4    Schläfli, E.5    Dukor, P.6
  • 17
    • 0024452645 scopus 로고
    • Muramylpeptides and lipopeptides: Studies towards immunostimulants
    • Baschang, G. 1989. Muramylpeptides and lipopeptides: studies towards immunostimulants. Tetrahedron. 45:6331-6360.
    • (1989) Tetrahedron , vol.45 , pp. 6331-6360
    • Baschang, G.1
  • 18
    • 0014192623 scopus 로고
    • Release of endogenous pyrogen by human monocytes
    • Bodel, P., and E. Atkins. 1967. Release of endogenous pyrogen by human monocytes. N. Engl. J. Med. 276:1002-1008.
    • (1967) N. Engl. J. Med. , vol.276 , pp. 1002-1008
    • Bodel, P.1    Atkins, E.2
  • 19
    • 0018100081 scopus 로고
    • Characterization of lymphocyte-activating factor (LAP) produced by a macrophage cell line, P388D1. II. Biochemical characterization of LAF induced by activated T cells and LPS
    • Mizel, S.B., J.J. Oppenheim, and D.L. Rosenstreich. 1978. Characterization of lymphocyte-activating factor (LAP) produced by a macrophage cell line, P388D1. II. Biochemical characterization of LAF induced by activated T cells and LPS. J. Immunol. 120:1504-1508.
    • (1978) J. Immunol. , vol.120 , pp. 1504-1508
    • Mizel, S.B.1    Oppenheim, J.J.2    Rosenstreich, D.L.3
  • 20
    • 0026658625 scopus 로고
    • Macrophage response to bacteria: Induction of marked secretory and cellular activities by lipoteichoic acids
    • Keller, R., W. Fischer, R. Keist, and S. Bassetti. 1992. Macrophage response to bacteria: induction of marked secretory and cellular activities by lipoteichoic acids. Infect. Immun. 60: 3664-3672.
    • (1992) Infect. Immun. , vol.60 , pp. 3664-3672
    • Keller, R.1    Fischer, W.2    Keist, R.3    Bassetti, S.4
  • 21
    • 0023891497 scopus 로고
    • Stimulation of human and murine adherent cells by bacterial lipoprotein and synthetic lipopeptide analogues
    • Hoffmann, P., S. Heinle, U.F. Schade, H. Loppnow, A.J. Ulmer, H.-D. Flad, G. Jung, and W. Bessler. 1988. Stimulation of human and murine adherent cells by bacterial lipoprotein and synthetic lipopeptide analogues. Immunobiology. 177: 158-170.
    • (1988) Immunobiology , vol.177 , pp. 158-170
    • Hoffmann, P.1    Heinle, S.2    Schade, U.F.3    Loppnow, H.4    Ulmer, A.J.5    Flad, H.-D.6    Jung, G.7    Bessler, W.8
  • 22
    • 0020538479 scopus 로고
    • Induction of macrophage-mediated cytolysis of neoplastic cells by mycoplasmas
    • Loewenstein, J., S. Rottem, and R. Gallily. 1983. Induction of macrophage-mediated cytolysis of neoplastic cells by mycoplasmas. Cell. Immunol. 77:290-297.
    • (1983) Cell. Immunol. , vol.77 , pp. 290-297
    • Loewenstein, J.1    Rottem, S.2    Gallily, R.3
  • 23
    • 0029991018 scopus 로고    scopus 로고
    • The sequence of the Mycoplasma arthritidis superantigen MAM: Identification of functional domains and comparison with microbial superantigens and plant lectin mitogens
    • Cole, B.C., K.L. Knudtson, A. Oliphant, A.D. Sawatzke, A. Pole, M. Manohar, L.S. Benson, E. Ahmed, and C.L. Atkin. 1996. The sequence of the Mycoplasma arthritidis superantigen MAM: identification of functional domains and comparison with microbial superantigens and plant lectin mitogens. J. Exp. Med. 183:1105-1110.
    • (1996) J. Exp. Med. , vol.183 , pp. 1105-1110
    • Cole, B.C.1    Knudtson, K.L.2    Oliphant, A.3    Sawatzke, A.D.4    Pole, A.5    Manohar, M.6    Benson, L.S.7    Ahmed, E.8    Atkin, C.L.9
  • 24
    • 0028070650 scopus 로고
    • Purification and partial biochemical characterization of a Mycoplasma fermentans-derived substance that activates macrophages to release nitric oxide, TNF, and IL-6
    • Mühlradt, P.F., and M. Frisch. 1994. Purification and partial biochemical characterization of a Mycoplasma fermentans-derived substance that activates macrophages to release nitric oxide, TNF, and IL-6. Infect. Immun. 62:3801-3807.
    • (1994) Infect. Immun. , vol.62 , pp. 3801-3807
    • Mühlradt, P.F.1    Frisch, M.2
  • 26
    • 0028085450 scopus 로고
    • Mycoplasma arginini TUH-14 membrane lipoproteins induce production of interleukin-1, interleukin-6, and tumor necrosis factor alpha by human monocytes
    • Herbelin, A., E. Ruuth, D. Delorme, C. Michel-Herbelin, and F. Praz. 1994. Mycoplasma arginini TUH-14 membrane lipoproteins induce production of interleukin-1, interleukin-6, and tumor necrosis factor alpha by human monocytes. Infect. Immun. 62:4690-4694.
    • (1994) Infect. Immun. , vol.62 , pp. 4690-4694
    • Herbelin, A.1    Ruuth, E.2    Delorme, D.3    Michel-Herbelin, C.4    Praz, F.5
  • 27
    • 0027956306 scopus 로고
    • A 48-kilodalton Mycoplasma fermentans membrane protein induces cytokine secretion by human monocytes
    • Kostyal, D.A., G.H. Butler, and D.H. Beezhold. 1994. A 48-kilodalton Mycoplasma fermentans membrane protein induces cytokine secretion by human monocytes. Infect. Immun. 62: 3793-3800.
    • (1994) Infect. Immun. , vol.62 , pp. 3793-3800
    • Kostyal, D.A.1    Butler, G.H.2    Beezhold, D.H.3
  • 28
    • 0030034115 scopus 로고    scopus 로고
    • Mycoplasma membrane lipoproteins induce proinflammatory cytokines by a mechanism distinct from that of lipopolysaccharide
    • Rawadi, G., and S. Roman-Roman. 1996. Mycoplasma membrane lipoproteins induce proinflammatory cytokines by a mechanism distinct from that of lipopolysaccharide. Infect. Immun. 64:637-643.
    • (1996) Infect. Immun. , vol.64 , pp. 637-643
    • Rawadi, G.1    Roman-Roman, S.2
  • 29
    • 0029977481 scopus 로고    scopus 로고
    • Identification of S-(2,3-dihydroxypropyl)cysteine in a macrophage-activating lipopeptide from Mycoplasma fermentans
    • Mühlradt, P.F., H. Meyer, and R. Jansen. 1996. Identification of S-(2,3-dihydroxypropyl)cysteine in a macrophage-activating lipopeptide from Mycoplasma fermentans. Biochem. 35:7781-7786.
    • (1996) Biochem. , vol.35 , pp. 7781-7786
    • Mühlradt, P.F.1    Meyer, H.2    Jansen, R.3
  • 30
    • 0026051608 scopus 로고
    • MDHM, a macrophage-stimulatory product of Mycoplasma fermentans, leads to in vitro interleukin-1 (IL-1), IL-6, tumor necrosis factor, and prostaglandin production and is pyrogenic in rabbits
    • Mühlradt, P.F., and U. Schade. 1991. MDHM, a macrophage-stimulatory product of Mycoplasma fermentans, leads to in vitro interleukin-1 (IL-1), IL-6, tumor necrosis factor, and prostaglandin production and is pyrogenic in rabbits. Infect. Immun. 59:3969-3974.
    • (1991) Infect. Immun. , vol.59 , pp. 3969-3974
    • Mühlradt, P.F.1    Schade, U.2
  • 31
    • 0027361971 scopus 로고
    • MDHM, a macrophage-activating product from Mycoplasma fermentans, stimulates murine macrophages to synthesize nitric oxide and become tumoricidal
    • Ruschmeyer, D., H.J. Thude, and P.F. Mühlradt. 1993. MDHM, a macrophage-activating product from Mycoplasma fermentans, stimulates murine macrophages to synthesize nitric oxide and become tumoricidal. FEMS Immunol. Med. Microbiol. 7:223-230.
    • (1993) FEMS Immunol. Med. Microbiol. , vol.7 , pp. 223-230
    • Ruschmeyer, D.1    Thude, H.J.2    Mühlradt, P.F.3
  • 32
    • 0029979938 scopus 로고    scopus 로고
    • Mycoplasma fermentans-derived lipid inhibits class II major histocompatibility complex expression without mediation by interleukin-6, interleukin-10, tumor necrosis factor, transforming growth factor-β, type I interferon, prostaglandins or nitric oxide
    • Frisch, M., G. Gradehandt, and P.F. Mühlradt. 1996. Mycoplasma fermentans-derived lipid inhibits class II major histocompatibility complex expression without mediation by interleukin-6, interleukin-10, tumor necrosis factor, transforming growth factor-β, type I interferon, prostaglandins or nitric oxide. Eur J. Immunol. 26:1050-1057.
    • (1996) Eur J. Immunol. , vol.26 , pp. 1050-1057
    • Frisch, M.1    Gradehandt, G.2    Mühlradt, P.F.3
  • 33
    • 0028940959 scopus 로고
    • Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic peptides activate monocytes/macrophages
    • Radolf, J.D., L.L. Arndt, D.R. Akins, L.L. Curetty, M.E. Levi, Y. Shen, L.S. Davis, and M.V. Norgard. 1995. Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic peptides activate monocytes/macrophages. J. Immunol. 154:2866-2877.
    • (1995) J. Immunol. , vol.154 , pp. 2866-2877
    • Radolf, J.D.1    Arndt, L.L.2    Akins, D.R.3    Curetty, L.L.4    Levi, M.E.5    Shen, Y.6    Davis, L.S.7    Norgard, M.V.8
  • 34
    • 77956860575 scopus 로고
    • Lipoproteins, structure, function, biosynthesis and model for protein export
    • J.-M. Ghuysen and R. Hakenbeck, editors. Elsevier Science, Amsterdam
    • Braun, V., and H.C. Wu. 1994. Lipoproteins, structure, function, biosynthesis and model for protein export. In Bacterial Cell Wall. J.-M. Ghuysen and R. Hakenbeck, editors. Elsevier Science, Amsterdam. 319-341.
    • (1994) Bacterial Cell Wall , pp. 319-341
    • Braun, V.1    Wu, H.C.2
  • 35
    • 0027474842 scopus 로고
    • Tyrosine phosphorylation of mitogen-activated protein kinases is necessary for activation of murine macrophages by natural and synthetic bacterial products
    • Dong, Z., X. Qi, and I. Fidler. 1993. Tyrosine phosphorylation of mitogen-activated protein kinases is necessary for activation of murine macrophages by natural and synthetic bacterial products. J. Exp. Med. 177:1071-1077.
    • (1993) J. Exp. Med. , vol.177 , pp. 1071-1077
    • Dong, Z.1    Qi, X.2    Fidler, I.3
  • 39
    • 0029979976 scopus 로고    scopus 로고
    • Influence of matrix solution conditions on the MALDI-MS analysis of peptides and proteins
    • Cohen, S.L., and B.T. Chait. 1996. Influence of matrix solution conditions on the MALDI-MS analysis of peptides and proteins. Anal. Chem. 68:31-37.
    • (1996) Anal. Chem. , vol.68 , pp. 31-37
    • Cohen, S.L.1    Chait, B.T.2
  • 40
    • 0026338581 scopus 로고
    • Synthesis of N-Fmoc protected derivatives of S-(2,3-dihydroxypropyl)-cysteine and their application in peptide synthesis
    • Metzger, J.W., K.-H. Wiesmüller, and G. Jung. 1991. Synthesis of N-Fmoc protected derivatives of S-(2,3-dihydroxypropyl)-cysteine and their application in peptide synthesis. Int. J. Pep. Protein. Res. 38:545-554.
    • (1991) Int. J. Pep. Protein. Res. , vol.38 , pp. 545-554
    • Metzger, J.W.1    Wiesmüller, K.-H.2    Jung, G.3
  • 41
    • 0029295032 scopus 로고
    • Synthetic S-(2,3-dihydroxypropyl)-cysteinyl peptides derived from the N-terminus of the cytochrome subunit of the photoreaction centre of Rhodopseudomonas viridis enhance murine splenocyte proliferation
    • Metzger, J.W., A.G. Beck-Sickinger, M. Loleit, M. Eckert, W.G. Bessler, and G. Jung. 1995. Synthetic S-(2,3-dihydroxypropyl)-cysteinyl peptides derived from the N-terminus of the cytochrome subunit of the photoreaction centre of Rhodopseudomonas viridis enhance murine splenocyte proliferation. J. Pept. Sci. 3:184-190.
    • (1995) J. Pept. Sci. , vol.3 , pp. 184-190
    • Metzger, J.W.1    Beck-Sickinger, A.G.2    Loleit, M.3    Eckert, M.4    Bessler, W.G.5    Jung, G.6
  • 42
    • 0027360077 scopus 로고
    • Differential expression and surface presentation generate high-frequency antigenic variation in Mycoplasma fermentans
    • Theiss, P.M., M.F. Kim, and K.S. Wise. 1993. Differential expression and surface presentation generate high-frequency antigenic variation in Mycoplasma fermentans. Infect. Immun. 61:5123-5128.
    • (1993) Infect. Immun. , vol.61 , pp. 5123-5128
    • Theiss, P.M.1    Kim, M.F.2    Wise, K.S.3
  • 43
    • 0015611501 scopus 로고
    • Covalent binding of lipid to protein. Diglyceride and amide-linked fatty acid at the N-terminal end of the murein-lipoprotein of the Escherichia coli outer membrane
    • Hantke, K., and V. Braun. 1973. Covalent binding of lipid to protein. Diglyceride and amide-linked fatty acid at the N-terminal end of the murein-lipoprotein of the Escherichia coli outer membrane. Eur. J. Biochem. 34:284-296.
    • (1973) Eur. J. Biochem. , vol.34 , pp. 284-296
    • Hantke, K.1    Braun, V.2
  • 44
    • 84985570367 scopus 로고
    • Increased production of specific antibodies by presentation of the antigen determinants with covalently coupled lipopeptide mitogens
    • Jung, G., K.-H. Wiesmüller, G. Becker, H.-J. Bühring, and W.G. Bessler. 1985. Increased production of specific antibodies by presentation of the antigen determinants with covalently coupled lipopeptide mitogens. Angew. Chem. Int. Ed. Engl. 24:872-873.
    • (1985) Angew. Chem. Int. Ed. Engl. , vol.24 , pp. 872-873
    • Jung, G.1    Wiesmüller, K.-H.2    Becker, G.3    Bühring, H.-J.4    Bessler, W.G.5
  • 45
    • 0028017286 scopus 로고
    • Mitogenic activity and the induction of tumor necrosis factor by lipopeptide analogs of the N-terminal part of lipoprotein in the outer membrane of Escherichia coli
    • Shimizu, T., Y. Iwamoto, Y. Yanagahira, M. Kurimura, and K. Achiwa. 1994. Mitogenic activity and the induction of tumor necrosis factor by lipopeptide analogs of the N-terminal part of lipoprotein in the outer membrane of Escherichia coli. Biol. Pharm. Bull. 17:980-982.
    • (1994) Biol. Pharm. Bull. , vol.17 , pp. 980-982
    • Shimizu, T.1    Iwamoto, Y.2    Yanagahira, Y.3    Kurimura, M.4    Achiwa, K.5
  • 46
    • 0024495638 scopus 로고
    • Novel low-molecular weight synthetic vaccine against foot-and-mouth disease containing a potent B-cell and macrophage activator
    • Wiesmüller, K.-H., G. Jung, and G. Hess. 1989. Novel low-molecular weight synthetic vaccine against foot-and-mouth disease containing a potent B-cell and macrophage activator. Vaccine. 7:29-33.
    • (1989) Vaccine , vol.7 , pp. 29-33
    • Wiesmüller, K.-H.1    Jung, G.2    Hess, G.3
  • 47
    • 0026483351 scopus 로고
    • Solid phase peptide synthesis of lipopeptide vaccines eliciting epitope specific B-, T-helper and T-killer cell response
    • Wiesmüller, K.-H., W. Bessler, and G. Jung. 1992. Solid phase peptide synthesis of lipopeptide vaccines eliciting epitope specific B-, T-helper and T-killer cell response. Int. J. Pep. Protein Res. 40:255-266.
    • (1992) Int. J. Pep. Protein Res. , vol.40 , pp. 255-266
    • Wiesmüller, K.-H.1    Bessler, W.2    Jung, G.3
  • 48
    • 0024389666 scopus 로고
    • In vivo priming of virus specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine
    • Deres, K., H.-J. Schild, K.-H. Wiesmüller, G. Jung, and H.-G. Rammensee. 1989. In vivo priming of virus specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine. Nature (Lond.). 342:561-564.
    • (1989) Nature (Lond.) , vol.342 , pp. 561-564
    • Deres, K.1    Schild, H.-J.2    Wiesmüller, K.-H.3    Jung, G.4    Rammensee, H.-G.5
  • 49
    • 0026091287 scopus 로고
    • Efficiency of peptides and lipopeptides for in vivo priming of virus specific cytotoxic T-cells
    • Schild, H.-J., K. Deres, K.-H. Wiesmüller, G. Jung, and H.-G. Rammensee. 1991. Efficiency of peptides and lipopeptides for in vivo priming of virus specific cytotoxic T-cells. Eur. J. Immunol. 21:2649-2654.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 2649-2654
    • Schild, H.-J.1    Deres, K.2    Wiesmüller, K.-H.3    Jung, G.4    Rammensee, H.-G.5
  • 50
    • 0028131274 scopus 로고
    • Efficacy of synthetic lipopeptides in the induction of cytotoxic T lymphocytes: Comparison of the costimulating support provided by helper T cells and lipoaminoacid
    • Borges, E., K.-H. Wiesmüller, G. Jung, and P. Walden. 1994. Efficacy of synthetic lipopeptides in the induction of cytotoxic T lymphocytes: comparison of the costimulating support provided by helper T cells and lipoaminoacid. J. Immunol. Methods. 173:253-263.
    • (1994) J. Immunol. Methods , vol.173 , pp. 253-263
    • Borges, E.1    Wiesmüller, K.-H.2    Jung, G.3    Walden, P.4
  • 52
    • 0025744714 scopus 로고
    • Successive synovial Mycoplasma hominis isolates exhibit apparent antigenic variation
    • Olson, L.D., C.A. Renshaw, S.W. Shane, and M.F. Barile. 1991. Successive synovial Mycoplasma hominis isolates exhibit apparent antigenic variation. Infect. Immun. 59:3327-3329.
    • (1991) Infect. Immun. , vol.59 , pp. 3327-3329
    • Olson, L.D.1    Renshaw, C.A.2    Shane, S.W.3    Barile, M.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.