HIV type 1 chemokine receptor usage in mother-to-child transmission

AIDS Research and Human Retroviruses

Volumn 17, Issue 10, 2001, Pages 925-935

  Salvatori, F ^a   Scarlatti, G ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR2B; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR6; RECEPTOR BOB; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN;

ALLELE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENOTYPE; HETEROZYGOSITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFANT; MOTHER; MUTATION; PHENOTYPE; PRIORITY JOURNAL; PROVIRUS; RISK FACTOR; SEQUENCE ANALYSIS; VERTICAL TRANSMISSION; VIRUS INFECTIVITY; VIRUS REPLICATION; VIRUS TRANSMISSION;

AMINO ACID SEQUENCE; BASE SEQUENCE; CELL LINE; DISEASE TRANSMISSION, VERTICAL; FEMALE; GENES, ENV; HETEROZYGOTE; HIV-1; HUMANS; INFANT; INFANT, NEWBORN; MOLECULAR SEQUENCE DATA; MUTATION; PHYLOGENY; POLYMERASE CHAIN REACTION; PREGNANCY; RECEPTORS, CCR5; RECEPTORS, CXCR4; RISK FACTORS; RNA, VIRAL; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; VIRUS REPLICATION;

EID: 0034820906     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/088922201750290041     Document Type: Article

References (74)

1. The Working Group on Mother-to-Child Transmission of HIV Rates of mother-to-child transmission of HIV in Africa, America and Europe: Results from 13 perinatal studies
2. Perinatal HIV-1 transmission: Recent advances and therapeutic interventions
3. Quantitation of human immunodeficiency virus type 1 during pregnancy: Relationship of viral titer to mother-to-child transmission and stability of viral load
4. Identification of levels of maternal HIV-1 RNA associated with risk of perinatal transmission. Effect of maternal zidovudine treatment on viral load
5. Maternal HIV-1 viral load and vertical transmission of infection: The Ariel Project for the prevention of HIV transmission from mother to infant
6. Maternal plasma human immunodeficiency virus type 1 RNA level: A determinant and projected threshold for mother-to-child transmission
7. Presence of antibodies to HIV-1 gp120 Env epitopes correlates with uninfected status of the children born to seropositive mothers
8. Vertical transmission of human immunodeficiency virus is correlated with the absence of high affinity/avidity maternal antibodies to the gp120 principal neutralizing domain
9. Mother-to-child transmission of human immunodeficiency virus type 1: Correlation with neutralizing antibodies against primary isolates
10. Lack of autologous neutralizing antibody to human immunodeficiency virus type 1 (HIV-1) and macrophage tropism are associated with mother-to-infant transmission
11. Transmission of human immunodeficiency virus type 1 (HIV-1) from mother-to-child correlates with viral phenotype
12. Viral phenotype and host-cell susceptibility to HIV-1 infection as risk factors for mother-to-child HIV-1 transmission
13. Features of HIV-1 that could influence maternal-child transmission
14. HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor
15. The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates
16. Identification of a major co-receptor for primary isolates of HIV-1
17. Expression cloning of new receptors used by simian and human im-munodeficiency viruses
18. Use of coreceptors other than CCR5 by non-syncytium-inducing adult and pediatric isolates of human immunodeficiency virus type 1 is rare in vitro
19. CC CRK5: A RANTES, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1
20. The amino-terminal domain of the CCR2 chemokine receptor acts as coreceptor for HIV-1 infection
21. STRL33, a novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1
22. TYMSTR, a putative chemokine receptor selectively expressed in activated T cells, exhibits HIV-1 coreceptor function
23. A new classification for HIV-1
24. A dual-tropic primary HIV-1 isolate that uses fusin and the β-chemokine receptors CKR-5, CKR-3, and CRK-2b as fusion cofactors
25. Primary, syncytium-inducing human immunodeficiency virus type 1 isolates are dual-tropic and most can use either Lestr or CCR5 as coreceptors for virus entry
26. In vivo evolution of HIV-1 coreceptor usage and sensitivity to chemokine-mediated suppression
27. CCR5- and CXCR4-tropic HIV-1 are equally cytopathic for their targets in human lymphoid tissue
28. Adaptation to promiscuous usage of chemokine receptors is not a prerequisite for human immunodeficiency virus type 1 disease progression
29. Evolution of syncytium-inducing and non-syncytium-inducing biological virus clones in relation to replication kinetics during the course of human immunodeficiency virus type 1 infection
30. Persistent CCR5 utilization and enhanced macrophage tropism by primary blood human immunodeficiency virus type 1 isolates from advanced stages of disease and comparison to tissue-derived isolates
31. Coreceptor usage of HIV-1 isolates representing different genetic subtypes obtained from pregnant Cameroonian women
32. Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission
33. Evolution of human immunodeficiency virus type 1 in HIV-1 perinatally infected infants with rapid and slow progression to disease
34. Genetic analysis of human immunodeficiency virus type 1 envelope V3 region isolates from mothers and infants after perinatal transmission
35. Genomic human immunodeficiency virus type 1 RNA variation in mother and child following intra-uterine virus transmission
36. Comparison of variable region 3 sequences of human immunodeficiency virus type 1 from infected children with the RNA and DNA sequences of the virus populations of their mothers
37. Selective transmission of human immunodeficiency virus type 1 variants from mothers to infants
38. Persistence of multiple maternal genotypes of human immunodeficiency virus type 1 in infants infected by vertical transmission
39. Molecular evidence for mother-to-child transmission of multiple variants by analysis of RNA and DNA sequences of human immunodeficiency virus type 1
40. Classification system for human immunodeficiency virus (HIV) infection in children under 13 years of age
41. Polymerase chain reaction, virus isolation and antigen assay in HIV-1 antibody positive mothers and their children
42. Construction of recombinant murine retroviruses that expresses the human T-cell leukemia virus type II and human T-cell lymphotropic virus type III trans activator genes
43. Dissociation of gp120 from HIV-1 virions induced by soluble CD4
44. Phylogenies from molecular sequences: Inference and reliability
45. Minimal requirements for the human immunodeficiency virus type 1 V3 domain to support the syncytium-inducing phenotype: Analysis by single amino acid substitution
46. Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule
47. Determination of coreceptor usage of human immunodeficiency virus type 1 from patient plasma samples using a recombinant phenotypic assay
48. Lack of correlation between V3 amino acid sequence and syncytium-inducing capacity of some HIV type 1 isolates
49. CCR5 coreceptor usage of non-syncytium-inducing primary HIV-1 is independent of phylogenetically distinct global domain that predicts CCR5 usage
50. Prognostic value of a CCR5 defective allele in pediatric HIV-1 infection
51. Diagnosis of HIV infection in infants and children
52. Conversion rate towards a syncytium-inducing (SI) phenotype during different stages of human immunodeficiency virus type 1 infection and prognostic value of SI phenotype for survival after AIDS diagnosis
53. CCR5 HIV-1 vertical transmission
54. Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype
55. Selection of maternal human immunodeficiency virus type 1 variants in human placenta
56. HIV-1 proviral DNA polymerase chain reaction detection in chorionic villi after exclusion of maternal contamination by variable number of tandem repeats analysis
57. Vertical transmission of HIV: Detection of proviral DNA in placental trophoblast
58. Cell-to-cell contact results in a selective translocation of maternal HIV-1 quasispecies across a trophoblastic barrier by both transcytosis and infection
59. Proposed definitions for in utero versus intrapartum transmission of HIV-1
60. CCR5 expression correlates with susceptibility of maturing monocytes to human immunodeficiency virus type 1 infection
61. Differential tropism and chemokine receptor expression of human immunodeficiency virus type 1 in neonatal monocytes, monocyte-derived macrophages, and placental macrophages
62. Risk of mother-to-infant transmission of HIV-1 is not reduced in CCR5/delta32ccr5 heterozygotes
63. CCR5del32 in perinatal HIV-1 infection
64. CCR5 chemokine receptor variant in HIV-1 mother-to-child transmission and disease progression in children
65. Possible influence of the mutant CCR5 allele on vertical transmission of HIV-1
66. Expanded tropism of primary human immunodeficiency virus type 1 R5 strains to CD4(+) T-cell lines determined by the capacity to exploit low concentrations of CCR5
67. CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro
68. Decreased susceptibility of peripheral blood mononuclear cells from individuals heterozygous for a mutant CCR5 allele to HIV infection
69. Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposures
70. Chemokine receptor CCR5 genotype influences the kinetics of human immunodeficiency virus type 1 infection in human PBL-SCID mice
71. Restriction of HIV type 1 infection in macrophages heterozygous for a deletion in the CC-chemokine receptor 5 gene
72. Genital tract human immunodeficiency virus type 1 (HIV-1) shedding and inflammation and HIV-1 env diversity in perinatal HIV-1 transmission
73. Genetic characterization of human immunodeficiency virus type 1 in blood and genital secretions: Evidence for viral compartmentalization and selection during sexual transmission