The solution structure of an AlcR-DNA complex sheds light onto the unique tight and monomeric DNA binding of a Zn2Cys6 protein

Structure

Volumn 9, Issue 9, 2001, Pages 827-836

  Cahuzac, Bertrand ^a   Cerdan, Rachel ^a   Felenbok, Béatrice ^b   Guittet, Eric ^a  

^a INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

DNA binding protein; NMR structure; Transcriptional activation; Zinc binuclear cluster

Indexed keywords

AMINO ACID; BACTERIAL PROTEIN; CYSTEINE DERIVATIVE; DOUBLE STRANDED DNA; MONOMER; PROTEIN ALCR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ZINC;

AMINO TERMINAL SEQUENCE; ARTICLE; BASE PAIRING; BINDING SITE; COMPLEX FORMATION; CONSENSUS SEQUENCE; CRYSTAL STRUCTURE; DNA PROTEIN COMPLEX; DNA SEQUENCE; DNA STRUCTURE; GENE CLUSTER; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ASPERGILLUS NIDULANS; CYSTEINE; DNA; DNA-BINDING PROTEINS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEIN CONFORMATION; SOLUTIONS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; THERMODYNAMICS; ZINC;

ASPERGILLUS; BACTERIA (MICROORGANISMS); EMERICELLA NIDULANS;

EID: 0034815826     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(01)00640-2     Document Type: Article

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