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Volumn 16, Issue 11, 1996, Pages 6096-6102

A novel DNA binding motif for yeast zinc cluster proteins: The Leu3p and Pdr3p transcriptional activators recognize everted repeats

Author keywords

[No Author keywords available]

Indexed keywords

DNA; NUCLEOTIDE; ZINC FINGER PROTEIN;

EID: 0029802537     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.11.6096     Document Type: Article
Times cited : (61)

References (50)
  • 2
    • 0026571968 scopus 로고
    • Solution structure of the DNA-binding domain of Cd2-GAL4 from S. cerevisiae
    • Baleja, J. D., R. Marmorstein, S. C. Harrison, and G. Wagner. 1992. Solution structure of the DNA-binding domain of Cd2-GAL4 from S. cerevisiae. Nature (London) 356:450-453.
    • (1992) Nature (London) , vol.356 , pp. 450-453
    • Baleja, J.D.1    Marmorstein, R.2    Harrison, S.C.3    Wagner, G.4
  • 3
    • 0022684387 scopus 로고
    • A GAL family of upstream activating sequences in yeast: Roles in both induction and repression of transcription
    • Bram, R. J., N. F. Lue, and R. D. Kornberg. 1986. A GAL family of upstream activating sequences in yeast: roles in both induction and repression of transcription. EMBO J. 5:603-608.
    • (1986) EMBO J. , vol.5 , pp. 603-608
    • Bram, R.J.1    Lue, N.F.2    Kornberg, R.D.3
  • 4
    • 0025353853 scopus 로고
    • Regulation of yeast LEU2. Total deletion of regulatory gene LEU3 unmasks GCN4-dependent basal level expression of LEU2
    • Brisco, P. R., and G. B. Kohlhaw. 1990. Regulation of yeast LEU2. Total deletion of regulatory gene LEU3 unmasks GCN4-dependent basal level expression of LEU2. J. Biol. Chem. 265:11667-11675.
    • (1990) J. Biol. Chem. , vol.265 , pp. 11667-11675
    • Brisco, P.R.1    Kohlhaw, G.B.2
  • 5
    • 0024325083 scopus 로고
    • Altering DNA-binding specificity of GAL4 requires sequences adjacent to the zinc finger
    • Corton, J. C., and S. A. Johnston. 1989. Altering DNA-binding specificity of GAL4 requires sequences adjacent to the zinc finger. Nature (London) 340:724-727.
    • (1989) Nature (London) , vol.340 , pp. 724-727
    • Corton, J.C.1    Johnston, S.A.2
  • 6
    • 0024293409 scopus 로고
    • CYP1 (HAP1) regulator of oxygen-dependent gene expression in yeast. I. Overall organization of the protein sequence displays several novel structural domains
    • Creusot, F., J. Verdiere, M. Gaisne, and P. P. Slonimski. 1988. CYP1 (HAP1) regulator of oxygen-dependent gene expression in yeast. I. Overall organization of the protein sequence displays several novel structural domains. J. Mol. Biol. 204:263-276.
    • (1988) J. Mol. Biol. , vol.204 , pp. 263-276
    • Creusot, F.1    Verdiere, J.2    Gaisne, M.3    Slonimski, P.P.4
  • 7
    • 0029042698 scopus 로고
    • Positive autoregulation of the yeast transcription factor Pdr3p, which is involved in control of drug resistance
    • Delahodde, A., T. Delaveau, and C. Jacq. 1995. Positive autoregulation of the yeast transcription factor Pdr3p, which is involved in control of drug resistance. Mol. Cell. Biol. 15:4043-4050.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4043-4050
    • Delahodde, A.1    Delaveau, T.2    Jacq, C.3
  • 8
    • 0027998450 scopus 로고
    • PDR3, a new yeast regulatory gene, is homologous to PDR1 and controls the multidrug resistance phenomenon
    • Delaveau, T., A. Delahodde, E. Carvajal, J. Subik, and C. Jacq. 1994. PDR3, a new yeast regulatory gene, is homologous to PDR1 and controls the multidrug resistance phenomenon. Mol. Gen. Genet. 244:501-511.
    • (1994) Mol. Gen. Genet. , vol.244 , pp. 501-511
    • Delaveau, T.1    Delahodde, A.2    Carvajal, E.3    Subik, J.4    Jacq, C.5
  • 9
    • 0026754771 scopus 로고
    • Sequence of a 12.7 kb segment of yeast chromosome II identifies a PDR-like gene and several new open reading frames
    • Delaveau, T., C. Jacq, and J. Perea. 1992. Sequence of a 12.7 kb segment of yeast chromosome II identifies a PDR-like gene and several new open reading frames. Yeast 8:761-768.
    • (1992) Yeast , vol.8 , pp. 761-768
    • Delaveau, T.1    Jacq, C.2    Perea, J.3
  • 10
    • 0023957762 scopus 로고
    • Mutational analysis of upstream activation sequence 2 of the CYC1 gene of Saccharomyces cerevisiae: A HAP2-HAP3-responsive site
    • Forsburg, S. L., and L. Guarente. 1988. Mutational analysis of upstream activation sequence 2 of the CYC1 gene of Saccharomyces cerevisiae: a HAP2-HAP3-responsive site. Mol. Cell. Biol. 8:647-654.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 647-654
    • Forsburg, S.L.1    Guarente, L.2
  • 11
    • 0023391008 scopus 로고
    • LEU3 of Saccharomyces cerevisiae encodes a factor for control of RNA levels of a group of leucine-specific genes
    • Friden, P., and P. Schimmel. 1987. LEU3 of Saccharomyces cerevisiae encodes a factor for control of RNA levels of a group of leucine-specific genes. Mol. Cell. Biol. 7:2708-2717.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 2708-2717
    • Friden, P.1    Schimmel, P.2
  • 12
    • 0024039672 scopus 로고
    • LEU3 of Saccharomyces cerevisiae activates multiple genes for branched-chain amino acid biosynthesis by binding to a common decanucleotide core sequence
    • Friden, P., and P. Schimmel. 1988. LEU3 of Saccharomyces cerevisiae activates multiple genes for branched-chain amino acid biosynthesis by binding to a common decanucleotide core sequence. Mol. Cell. Biol. 8:2690-2697.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 2690-2697
    • Friden, P.1    Schimmel, P.2
  • 13
    • 0020739930 scopus 로고
    • Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site
    • Guarente, L., and T. Mason. 1983. Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site. Cell 32:1279-1286.
    • (1983) Cell , vol.32 , pp. 1279-1286
    • Guarente, L.1    Mason, T.2
  • 14
    • 0029872691 scopus 로고    scopus 로고
    • Mutations in target DNA elements of yeast HAP1 modulate its transcriptional activity without affecting DNA binding
    • Ha, N., K. Hellauer, and B. Turcotte. 1996. Mutations in target DNA elements of yeast HAP1 modulate its transcriptional activity without affecting DNA binding. Nucleic Acids Res. 24:1453-1459.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 1453-1459
    • Ha, N.1    Hellauer, K.2    Turcotte, B.3
  • 15
    • 0026681666 scopus 로고
    • New vectors for high level expression of recombinant proteins in bacteria
    • Hakes, D. J., and J. E. Dixon. 1992. New vectors for high level expression of recombinant proteins in bacteria. Anal. Biochem. 202:293-298.
    • (1992) Anal. Biochem. , vol.202 , pp. 293-298
    • Hakes, D.J.1    Dixon, J.E.2
  • 16
    • 0026069207 scopus 로고
    • Identification of base and backbone contacts used for DNA sequence recognition and high-affinity binding by LAC9, a transcription activator containing a C6 finger
    • Halvorsen, Y. C., K. Nandablan, and R. C. Dickson. 1991. Identification of base and backbone contacts used for DNA sequence recognition and high-affinity binding by LAC9, a transcription activator containing a C6 finger. Mol. Cell. Biol. 11:1777-1784.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 1777-1784
    • Halvorsen, Y.C.1    Nandablan, K.2    Dickson, R.C.3
  • 17
    • 0028936210 scopus 로고
    • The Saccharomyces cerevisiae LEU3 protein activates expression of GDH1, a key gene in nitrogen assimilation
    • Hu, Y., T. G. Cooper, and G. B. Kohlhaw. 1995. The Saccharomyces cerevisiae LEU3 protein activates expression of GDH1, a key gene in nitrogen assimilation. Mol. Cell. Biol. 15:52-57.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 52-57
    • Hu, Y.1    Cooper, T.G.2    Kohlhaw, G.B.3
  • 19
    • 0029036703 scopus 로고
    • Detection of leucine-independent DNA site occupancy of the yeast Leu3p transcriptional activator in vivo
    • Kirkpatrick, C. R., and P. Schimmel. 1995. Detection of leucine-independent DNA site occupancy of the yeast Leu3p transcriptional activator in vivo. Mol. Cell. Biol. 15:4021-4030.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4021-4030
    • Kirkpatrick, C.R.1    Schimmel, P.2
  • 21
    • 2642699794 scopus 로고
    • Rapid and efficient site-specific mutagenesis without phenotypic selection
    • Kunkel, T. A. 1985. Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc. Natl. Acad. Sci. USA 82:488-492.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 488-492
    • Kunkel, T.A.1
  • 22
    • 0025797255 scopus 로고
    • Complex transcriptional regulation of the Saccharomyces cerevisiae CYB2 gene encoding cytochrome b2: CYP1 (HAP1) activator binds to the CYB2 upstream activation site UAS1-B2
    • Lodi, T., and B. Guiard. 1991. Complex transcriptional regulation of the Saccharomyces cerevisiae CYB2 gene encoding cytochrome b2: CYP1 (HAP1) activator binds to the CYB2 upstream activation site UAS1-B2. Mol. Cell. Biol. 11:3762-3772.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 3762-3772
    • Lodi, T.1    Guiard, B.2
  • 23
    • 0026547747 scopus 로고
    • DNA recognition by GAL4: Structure of a protein-DNA complex
    • Marmorstein, R., M. Carey, M. Ptashne, and S. C. Harrison. 1992. DNA recognition by GAL4: structure of a protein-DNA complex. Nature (London) 356:408-414.
    • (1992) Nature (London) , vol.356 , pp. 408-414
    • Marmorstein, R.1    Carey, M.2    Ptashne, M.3    Harrison, S.C.4
  • 24
    • 0027993285 scopus 로고
    • Crystal structure of a PPR1-DNA complex: DNA recognition by proteins containing a Zn2Cys6 binuclear cluster
    • Marmorstein, R., and S. C. Harrison. 1994. Crystal structure of a PPR1-DNA complex: DNA recognition by proteins containing a Zn2Cys6 binuclear cluster. Genes Dev. 8:2504-2512.
    • (1994) Genes Dev. , vol.8 , pp. 2504-2512
    • Marmorstein, R.1    Harrison, S.C.2
  • 25
    • 0023649577 scopus 로고
    • Yeast HAP1 activator competes with the factor RC2 for binding to the upstream activation site UAS1 of the CYC1 gene
    • Pfeifer, K., B. Arcangioli, and L. Guarente. 1987. Yeast HAP1 activator competes with the factor RC2 for binding to the upstream activation site UAS1 of the CYC1 gene. Cell 49:9-18.
    • (1987) Cell , vol.49 , pp. 9-18
    • Pfeifer, K.1    Arcangioli, B.2    Guarente, L.3
  • 26
    • 0024979286 scopus 로고
    • Functional dissection and sequence of yeast HAP1 activator
    • Pfeifer, K., K. S. Kim, S. Kogan, and L. Guarente. 1989. Functional dissection and sequence of yeast HAP1 activator. Cell 56:291-301.
    • (1989) Cell , vol.56 , pp. 291-301
    • Pfeifer, K.1    Kim, K.S.2    Kogan, S.3    Guarente, L.4
  • 27
    • 0023649686 scopus 로고
    • Yeast HAP1 activator binds to two upstream activation sites of different sequence
    • Pfeifer, K., T. Prezant, and L. Guarente. 1987. Yeast HAP1 activator binds to two upstream activation sites of different sequence. Cell 49:19-27.
    • (1987) Cell , vol.49 , pp. 19-27
    • Pfeifer, K.1    Prezant, T.2    Guarente, L.3
  • 28
    • 0023409211 scopus 로고
    • Organization of the regulatory region of the yeast CYC7 gene: Multiple factors are involved in regulation
    • Prezant, T., K. Pfeifer, and L. Guarente. 1987. Organization of the regulatory region of the yeast CYC7 gene: multiple factors are involved in regulation. Mol. Cell. Biol. 7:3252-3259.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 3252-3259
    • Prezant, T.1    Pfeifer, K.2    Guarente, L.3
  • 29
    • 0027218382 scopus 로고
    • Determinants of binding-site specificity among yeast C6 zinc cluster proteins
    • Reece, R. J., and M. Ptashne. 1993. Determinants of binding-site specificity among yeast C6 zinc cluster proteins. Science 261:909-911.
    • (1993) Science , vol.261 , pp. 909-911
    • Reece, R.J.1    Ptashne, M.2
  • 30
    • 0028145335 scopus 로고
    • Molecular architecture of a Leu3p-DNA complex in solution: A biochemical approach
    • Remboutsika, E., and G. B. Kohlhaw. 1994. Molecular architecture of a Leu3p-DNA complex in solution: a biochemical approach. Mol. Cell. Biol. 14:5547-5557.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5547-5557
    • Remboutsika, E.1    Kohlhaw, G.B.2
  • 31
    • 0025148943 scopus 로고
    • cis- and trans-acting regulatory elements of the yeast URA3 promoter
    • Roy, A., F. Exinger, and R. Losson. 1990. cis- and trans-acting regulatory elements of the yeast URA3 promoter. Mol. Cell. Biol. 10:5257-5270.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 5257-5270
    • Roy, A.1    Exinger, F.2    Losson, R.3
  • 34
    • 0024367337 scopus 로고
    • The Saccharomyces cerevisiae PUT3 activator protein associates with proline-specific upstream activation sequences
    • Siddiqui, A. H., and M. C. Brandriss. 1989. The Saccharomyces cerevisiae PUT3 activator protein associates with proline-specific upstream activation sequences. Mol. Cell. Biol. 9:4706-4712.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 4706-4712
    • Siddiqui, A.H.1    Brandriss, M.C.2
  • 35
    • 0024669291 scopus 로고
    • A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
    • Sikorski, R. S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27.
    • (1989) Genetics , vol.122 , pp. 19-27
    • Sikorski, R.S.1    Hieter, P.2
  • 37
    • 0026481107 scopus 로고
    • In vitro transcriptional activation by a metabolic intermediate: Activation by LEU3 depends on alpha-isopropylmalate
    • Sze, J. Y., M. Woontner, J. A. Jaehning, and G. B. Kohlhaw. 1992. In vitro transcriptional activation by a metabolic intermediate: activation by LEU3 depends on alpha-isopropylmalate. Science 258:1143-1145.
    • (1992) Science , vol.258 , pp. 1143-1145
    • Sze, J.Y.1    Woontner, M.2    Jaehning, J.A.3    Kohlhaw, G.B.4
  • 38
    • 0028028333 scopus 로고
    • The DNA-binding domain of the yeast Saccharomyces cerevisiae CYP1(HAP1) transcription factor possesses two zinc ions which are complexed in a zinc cluster
    • Timmerman, J. E., B. Guiard, E. Shechter, M. A. Delsuc, J. Y. Lallemand, and M. Gervais. 1994. The DNA-binding domain of the yeast Saccharomyces cerevisiae CYP1(HAP1) transcription factor possesses two zinc ions which are complexed in a zinc cluster. Eur. J. Biochem. 225:593-599.
    • (1994) Eur. J. Biochem. , vol.225 , pp. 593-599
    • Timmerman, J.E.1    Guiard, B.2    Shechter, E.3    Delsuc, M.A.4    Lallemand, J.Y.5    Gervais, M.6
  • 39
    • 0027409151 scopus 로고
    • An everted repeat mediates retinoic acid induction of the γF-crystallin gene: Evidence of a direct role for retinoids in lens development
    • Tini, M., G. Otulakowski, M. L. Breitman, L.-C. Tsui, and V. Giguère. 1993. An everted repeat mediates retinoic acid induction of the γF-crystallin gene: evidence of a direct role for retinoids in lens development. Genes Dev. 7:295-307.
    • (1993) Genes Dev. , vol.7 , pp. 295-307
    • Tini, M.1    Otulakowski, G.2    Breitman, M.L.3    Tsui, L.-C.4    Giguère, V.5
  • 40
    • 0025340553 scopus 로고
    • The upstream activating sequence for L-leucine gene regulation in Saccharomyces cerevisiae
    • Tu, H., and M. J. Casadaban. 1990. The upstream activating sequence for L-leucine gene regulation in Saccharomyces cerevisiae. Nucleic Acids Res. 18:3923-3931.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 3923-3931
    • Tu, H.1    Casadaban, M.J.2
  • 41
    • 0026071771 scopus 로고
    • Zinc fingers, zinc clusters, and zinc twists in DNA-binding protein domains
    • Vallee, B. L., J. E. Coleman, and D. S. Auld. 1991. Zinc fingers, zinc clusters, and zinc twists in DNA-binding protein domains. Proc. Natl. Acad. Sci. USA 88:999-1003.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 999-1003
    • Vallee, B.L.1    Coleman, J.E.2    Auld, D.S.3
  • 42
    • 0027331505 scopus 로고
    • How do "Zn2 cys6" proteins distinguish between similar upstream activation sites? Comparison of the DNA-binding specificity of the GAL4 protein in vitro and in vivo
    • Vashee, S., H. Xu, S. A. Johnston, and T. Kodadek. 1993. How do "Zn2 cys6" proteins distinguish between similar upstream activation sites? Comparison of the DNA-binding specificity of the GAL4 protein in vitro and in vivo. J. Biol. Chem. 268:24699-24706.
    • (1993) J. Biol. Chem. , vol.268 , pp. 24699-24706
    • Vashee, S.1    Xu, H.2    Johnston, S.A.3    Kodadek, T.4
  • 43
    • 0024026479 scopus 로고
    • Co-ordinate control of synthesis of mitochondrial and nonmitochondrial hemoproteins: A binding site for the HAP1 (CYP1) protein in the UAS region of the yeast catalase T gene (CTT1)
    • Winkler, H., G. Adam, E. Mattes, M. Schanz, A. Hartig, and H. Ruis. 1988. Co-ordinate control of synthesis of mitochondrial and nonmitochondrial hemoproteins: a binding site for the HAP1 (CYP1) protein in the UAS region of the yeast catalase T gene (CTT1). EMBO J. 7:1799-1804.
    • (1988) EMBO J. , vol.7 , pp. 1799-1804
    • Winkler, H.1    Adam, G.2    Mattes, E.3    Schanz, M.4    Hartig, A.5    Ruis, H.6
  • 44
    • 0025194603 scopus 로고
    • The C6 zinc finger and adjacent amino acids determine DNA-binding specificity and affinity in the yeast activator proteins LAC9 and PPR1
    • Witte, M. M., and R. C. Dickson. 1990. The C6 zinc finger and adjacent amino acids determine DNA-binding specificity and affinity in the yeast activator proteins LAC9 and PPR1. Mol. Cell. Biol. 10:5128-5137.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 5128-5137
    • Witte, M.M.1    Dickson, R.C.2
  • 45
    • 0027536095 scopus 로고
    • Antibody-promoted dimerization bypasses the regulation of DNA binding by the heme domain of the yeast transcriptional activator HAP1
    • Zhang, L., O. Bermingham-McDonogh, B. Turcotte, and L. Guarente. 1993. Antibody-promoted dimerization bypasses the regulation of DNA binding by the heme domain of the yeast transcriptional activator HAP1. Proc. Natl. Acad. Sci. USA 90:2851-2855.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2851-2855
    • Zhang, L.1    Bermingham-McDonogh, O.2    Turcotte, B.3    Guarente, L.4
  • 46
    • 0028071873 scopus 로고
    • The yeast activator HAP1 - A GAL4 family member - binds DNA in a directly repeated orientation
    • Zhang, L., and L. Guarente. 1994. The yeast activator HAP1 - a GAL4 family member - binds DNA in a directly repeated orientation. Genes Dev. 8:2110-2119.
    • (1994) Genes Dev. , vol.8 , pp. 2110-2119
    • Zhang, L.1    Guarente, L.2
  • 47
    • 0023649925 scopus 로고
    • Structure of yeast regulatory gene LEU3 and evidence that LEU3 itself is under general amino acid control
    • Zhou, K., P. R. Brisco, A. E. Hinkkanen, and G. B. Kohlhaw. 1987. Structure of yeast regulatory gene LEU3 and evidence that LEU3 itself is under general amino acid control. Nucleic Acids Res. 15:5261-5273.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 5261-5273
    • Zhou, K.1    Brisco, P.R.2    Hinkkanen, A.E.3    Kohlhaw, G.B.4
  • 48
    • 0025124529 scopus 로고
    • Yeast regulatory protein LEU3: A structure-function analysis
    • Zhou, K. M., Y. L. Bai, and G. B. Kohlhaw. 1990. Yeast regulatory protein LEU3: a structure-function analysis. Nucleic Acids Res. 18:291-298.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 291-298
    • Zhou, K.M.1    Bai, Y.L.2    Kohlhaw, G.B.3
  • 49
    • 0025036827 scopus 로고
    • Transcriptional activator LEU3 of yeast. Mapping of the transcriptional activation function and significance of activation domain tryptophans
    • Zhou, K. M., and G. B. Kohlhaw. 1990. Transcriptional activator LEU3 of yeast. Mapping of the transcriptional activation function and significance of activation domain tryptophans. J. Biol. Chem. 265:17409-17412.
    • (1990) J. Biol. Chem. , vol.265 , pp. 17409-17412
    • Zhou, K.M.1    Kohlhaw, G.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.