Articular chondrocytes from animals with a dermatan sulfate storage disease undergo a high rate of apoptosis and release nitric oxide and inflammatory cytokines: A possible mechanism underlying degenerative joint disease in the mucopolysaccharidoses

Laboratory Investigation

Volumn 81, Issue 9, 2001, Pages 1319-1328

  Simonaro, Calogera M ^a   Haskins, Mark E ^b   Schuchman, Edward H ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; CYTOKINE; DERMATAN SULFATE; GLYCOSAMINOGLYCAN; N ACETYLGALACTOSAMINE 4 SULFATASE; NITRIC OXIDE; PROTEOGLYCAN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ARTICULAR CARTILAGE; BONE DEVELOPMENT; CARTILAGE CELL; CAT; CELL CULTURE; CLINICAL FEATURE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME DEFICIENCY; IMMUNOHISTOCHEMISTRY; LYSOSOME STORAGE DISEASE; MAROTEAUX LAMY SYNDROME; MUCOPOLYSACCHARIDOSIS; NICK END LABELING; NONHUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; RAT;

EID: 0034814719     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3780345     Document Type: Article

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