메뉴 건너뛰기




Volumn 98, Issue 4, 1996, Pages 914-922

A lung-specific neo-antigen elicits specific CD8+ T cell tolerance with preserved CD4+ T cell reactivity: Implications for immune-mediated lung disease

Author keywords

alveolar cell; lung injury; lymphocyte; tolerance; transgene

Indexed keywords

CD4 ANTIGEN; HEMAGGLUTININ; SURFACTANT PROTEIN C; UNCLASSIFIED DRUG;

EID: 0029811940     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118874     Document Type: Article
Times cited : (22)

References (46)
  • 1
    • 0023663430 scopus 로고
    • T cell tolerance by clonal elimination in the thymus
    • Kappler, J., N. Roehm, and P. Marrack. 1987. T cell tolerance by clonal elimination in the thymus. Cell. 49:273-280.
    • (1987) Cell , vol.49 , pp. 273-280
    • Kappler, J.1    Roehm, N.2    Marrack, P.3
  • 6
    • 0028151819 scopus 로고
    • Negative selection of lymphocytes
    • Nossal, G.J.V. 1994. Negative selection of lymphocytes. Cell. 76:229-236.
    • (1994) Cell , vol.76 , pp. 229-236
    • Nossal, G.J.V.1
  • 7
    • 0343608675 scopus 로고
    • Transgenic mice and immunological tolerance
    • Moller, G. 1991. Transgenic mice and immunological tolerance. Immunol. Rev. 204(122).
    • (1991) Immunol. Rev. , vol.204 , Issue.122
    • Moller, G.1
  • 8
    • 0025923310 scopus 로고
    • A transgenic approach to the study of peripheral T cell tolerance
    • Miller, J.F.A.P., G. Morahan, J. Allison, M. Hoffmann. 1991. A transgenic approach to the study of peripheral T cell tolerance. Immunol. Rev. (122):103-116.
    • (1991) Immunol. Rev. , Issue.122 , pp. 103-116
    • Miller, J.F.A.P.1    Morahan, G.2    Allison, J.3    Hoffmann, M.4
  • 10
    • 0025754853 scopus 로고
    • Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: Role of anti-self (virus) immune response
    • Oldstone, M., M. Nerenberg, P. Southern, J. Price, and H. Lewicki. 1991. Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response. Cell. 65:319-331.
    • (1991) Cell , vol.65 , pp. 319-331
    • Oldstone, M.1    Nerenberg, M.2    Southern, P.3    Price, J.4    Lewicki, H.5
  • 12
    • 0025640849 scopus 로고
    • Structure and expression of the pulmonary surfactant protein SP-C gene in the mouse
    • Glasser, S., T. Korfhagen, M. Bruno, C. Dey, and J. Whitsett. 1990. Structure and expression of the pulmonary surfactant protein SP-C gene in the mouse. J. Biol. Chem. 265(35):21986-21991.
    • (1990) J. Biol. Chem. , vol.265 , Issue.35 , pp. 21986-21991
    • Glasser, S.1    Korfhagen, T.2    Bruno, M.3    Dey, C.4    Whitsett, J.5
  • 14
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid-guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid-guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 15
    • 0025269662 scopus 로고
    • In Situ Hybridization
    • F. Gorstein and A. Thor, editors. W.B. Saunders, Philadelpia, PA
    • Stoler, M. 1990. In Situ Hybridization. In Clinics in Laboratory Medicine: Tumor Markers in Diagnostic Pathology. Vol. 10. F. Gorstein and A. Thor, editors. W.B. Saunders, Philadelpia, PA. 215-236.
    • (1990) Clinics in Laboratory Medicine: Tumor Markers in Diagnostic Pathology , vol.10 , pp. 215-236
    • Stoler, M.1
  • 16
    • 0028087712 scopus 로고
    • In situ hybridization analysis of lymphoproliferative disorders: Assessment of clonality by immunoglobulin light chain messenger RNA expression
    • Segal, G., E. Shick, A. Fishleder, R. Tubbs, and M. Stoler. 1994. In situ hybridization analysis of lymphoproliferative disorders: assessment of clonality by immunoglobulin light chain messenger RNA expression. Diagn. Molec. Pathol. 3:170-177.
    • (1994) Diagn. Molec. Pathol. , vol.3 , pp. 170-177
    • Segal, G.1    Shick, E.2    Fishleder, A.3    Tubbs, R.4    Stoler, M.5
  • 17
    • 0002105653 scopus 로고
    • In situ hybridization with RNA probes: An annotated recipe
    • K. Valentino, and J. Barchus, editors. Oxford University Press, New York
    • Angerer, L., M. Stoler, and R. Angerer. 1987. In situ hybridization with RNA probes: an annotated recipe. In In Situ Hybridization: Applications to Neurobiology. K. Valentino, and J. Barchus, editors. Oxford University Press, New York. 42-70.
    • (1987) In Situ Hybridization: Applications to Neurobiology , pp. 42-70
    • Angerer, L.1    Stoler, M.2    Angerer, R.3
  • 18
    • 0019507483 scopus 로고
    • Heterogeneity and specificity of cloned lines of influenza-virus specific cylotoxic T lymphocytes
    • Braciale, T., M. Andrew, and V. Braciale. 1981. Heterogeneity and specificity of cloned lines of influenza-virus specific cylotoxic T lymphocytes. J. Exp. Med. 153(4):910-923.
    • (1981) J. Exp. Med. , vol.153 , Issue.4 , pp. 910-923
    • Braciale, T.1    Andrew, M.2    Braciale, V.3
  • 19
    • 0017540885 scopus 로고
    • Immunologic recognition of influenza virus-infected cells. I. Generation of a virus-strain specific and a cross-reactive subpopulation of cytotoxic T cells in the response to type A influenza viruses of different subtypes
    • Braciale, T. 1977. Immunologic recognition of influenza virus-infected cells. I. Generation of a virus-strain specific and a cross-reactive subpopulation of cytotoxic T cells in the response to type A influenza viruses of different subtypes. Cell Immunol. 33(2):423-436.
    • (1977) Cell Immunol. , vol.33 , Issue.2 , pp. 423-436
    • Braciale, T.1
  • 20
    • 0024421232 scopus 로고
    • A 15 amino acid fragment of influenza nucleoprotein synthesized in the cytoplasm is presented to class I restricted cytolytic T lymphocytes
    • Gould, K., J. Cossins, J. Bastin, G. Brownlee, and A. Townsend. 1989. A 15 amino acid fragment of influenza nucleoprotein synthesized in the cytoplasm is presented to class I restricted cytolytic T lymphocytes. J. Exp. Med. 170:1051-1056.
    • (1989) J. Exp. Med. , vol.170 , pp. 1051-1056
    • Gould, K.1    Cossins, J.2    Bastin, J.3    Brownlee, G.4    Townsend, A.5
  • 21
    • 0001237715 scopus 로고
    • Orthomyxoviruses
    • B. Fields, editor. Raven Press, New York
    • Murphy, B., and R. Webster. 1990. Orthomyxoviruses. In Virology. B. Fields, editor. Raven Press, New York. 1091-1152.
    • (1990) Virology , pp. 1091-1152
    • Murphy, B.1    Webster, R.2
  • 22
    • 0019126940 scopus 로고
    • Our immune defense against influenza
    • Askonas, B. 1980. Our immune defense against influenza. Biochem. Soc. Trans. 8:257-260.
    • (1980) Biochem. Soc. Trans. , vol.8 , pp. 257-260
    • Askonas, B.1
  • 23
    • 0017239733 scopus 로고
    • Analysis of the humoral immune response to influenza virus in vitro
    • Braciale, T., W. Gerhard, and N. Klinman. 1976. Analysis of the humoral immune response to influenza virus in vitro. J. Immunol. 116(3):827-834.
    • (1976) J. Immunol. , vol.116 , Issue.3 , pp. 827-834
    • Braciale, T.1    Gerhard, W.2    Klinman, N.3
  • 24
    • 0020655343 scopus 로고
    • Immunity to influenza in man
    • Couch, R., and J. Kasel. 1983. Immunity to influenza in man. Ann. Rev. Microbiol. 37:529-549.
    • (1983) Ann. Rev. Microbiol. , vol.37 , pp. 529-549
    • Couch, R.1    Kasel, J.2
  • 25
    • 0022503407 scopus 로고
    • The immune responses to influenza infection
    • Ada, G., and P. Jones. 1986. The immune responses to influenza infection. Curr. Topics Microbiol. Immunol. 128:1-54.
    • (1986) Curr. Topics Microbiol. Immunol. , vol.128 , pp. 1-54
    • Ada, G.1    Jones, P.2
  • 26
    • 0023517764 scopus 로고
    • The cell-mediated and humoral responses to influenza virus infection in the mouse lung
    • Ada, G., and P. Jones. 1987. The cell-mediated and humoral responses to influenza virus infection in the mouse lung. Adv. Exp. Med. Biol. 216B:1033-1042.
    • (1987) Adv. Exp. Med. Biol. , vol.216 B , pp. 1033-1042
    • Ada, G.1    Jones, P.2
  • 27
    • 0025298243 scopus 로고
    • Bovine and mouse serum β inhibitors of influenza A viruses are mannose-binding lectins
    • Anders, E., C. Hartley, and D. Jackson. 1990. Bovine and mouse serum β inhibitors of influenza A viruses are mannose-binding lectins. Proc. Natl. Acad. Sci. USA. 87:4485-4489.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 4485-4489
    • Anders, E.1    Hartley, C.2    Jackson, D.3
  • 28
    • 0026077241 scopus 로고
    • Recognition of the influenza hemagglutinin by class II MHC-restricted T lymphocytes and antibodies. I. Site definition and implications for antigen presentation and T lymphocyte recognition
    • Brown, L., N. Nygard, M. Graham, C. Bono, V. Braciale, J. Gorka, B. Schwartz, and T. Braciale. 1991. Recognition of the influenza hemagglutinin by class II MHC-restricted T lymphocytes and antibodies. I. Site definition and implications for antigen presentation and T lymphocyte recognition. J. Immunol. 147(8):2677-2684.
    • (1991) J. Immunol. , vol.147 , Issue.8 , pp. 2677-2684
    • Brown, L.1    Nygard, N.2    Graham, M.3    Bono, C.4    Braciale, V.5    Gorka, J.6    Schwartz, B.7    Braciale, T.8
  • 29
    • 0021821772 scopus 로고
    • Expression of specific cytolytic activity by H-21 region-restricted, influenza virus-specific T lymphocyte clones
    • Lukacher, A., L. Morrison, V. Braciale, B. Malissen, and T. Braciale. 1985. Expression of specific cytolytic activity by H-21 region-restricted, influenza virus-specific T lymphocyte clones. J. Exp. Med. 162(1):171-187.
    • (1985) J. Exp. Med. , vol.162 , Issue.1 , pp. 171-187
    • Lukacher, A.1    Morrison, L.2    Braciale, V.3    Malissen, B.4    Braciale, T.5
  • 30
    • 0022884283 scopus 로고
    • Distinguishable pathways of viral antigen presentation to T lymphocytes
    • Morrison, L., V. Braciale, and T. Braciale. 1986. Distinguishable pathways of viral antigen presentation to T lymphocytes. [Review]. Immunol. Rev. 5(4):294-304.
    • (1986) Immunol. Rev. , vol.5 , Issue.4 , pp. 294-304
    • Morrison, L.1    Braciale, V.2    Braciale, T.3
  • 31
    • 0022545321 scopus 로고
    • Differences in antigen presentation to MHC class I-and class II-restricted influenza virus-specific cytolytic T lymphocyte clones
    • Morrison, L., A. Lukacher, V. Braciale, D. Fan, and T. Braciale. 1986. Differences in antigen presentation to MHC class I-and class II-restricted influenza virus-specific cytolytic T lymphocyte clones. J. Exp. Med. 163(4):903-921.
    • (1986) J. Exp. Med. , vol.163 , Issue.4 , pp. 903-921
    • Morrison, L.1    Lukacher, A.2    Braciale, V.3    Fan, D.4    Braciale, T.5
  • 32
    • 0023680646 scopus 로고
    • Antigen form influences induction and frequency of influenza-specific class I and class II MHC-restricted cytolytic T lymphocytes
    • Morrison, L., V. Braciale, and T. Braciale. 1988. Antigen form influences induction and frequency of influenza-specific class I and class II MHC-restricted cytolytic T lymphocytes. J. Immunol. 141(2):363-368.
    • (1988) J. Immunol. , vol.141 , Issue.2 , pp. 363-368
    • Morrison, L.1    Braciale, V.2    Braciale, T.3
  • 34
    • 0024490951 scopus 로고
    • Class I major histocompatibility complex-restricted cytolytic T lymphocytes recognize a limited number of sites on the influenza hemagglutinin
    • Braciale, T., M. Sweetser, L. Morrison, D. Kittlesen, and V. Braciale. 1989. Class I major histocompatibility complex-restricted cytolytic T lymphocytes recognize a limited number of sites on the influenza hemagglutinin. Proc. Natl. Acad. Sci. USA. 86(1):277-281.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , Issue.1 , pp. 277-281
    • Braciale, T.1    Sweetser, M.2    Morrison, L.3    Kittlesen, D.4    Braciale, V.5
  • 35
    • 0024460877 scopus 로고
    • Class I major histocompatibility complex-restricted T lymphocyte recognition of the influenza hemagglutinin. Overlap between class I cytotoxic T lymphocytes and antibody sites
    • Sweetser, M., V. Braciale, and T. Braciale. 1989. Class I major histocompatibility complex-restricted T lymphocyte recognition of the influenza hemagglutinin. Overlap between class I cytotoxic T lymphocytes and antibody sites. J. Exp. Med 170(4):1357-1368.
    • (1989) J. Exp. Med , vol.170 , Issue.4 , pp. 1357-1368
    • Sweetser, M.1    Braciale, V.2    Braciale, T.3
  • 36
    • 0021243967 scopus 로고
    • In vivo effector function of influenza virus-specific cytotoxic T lymphocyte clones is highly specific
    • Lukacher, A., V. Braciale, and T. Braciale. 1984. In vivo effector function of influenza virus-specific cytotoxic T lymphocyte clones is highly specific. J. Exp. Med. 160(3):814-26.
    • (1984) J. Exp. Med. , vol.160 , Issue.3 , pp. 814-826
    • Lukacher, A.1    Braciale, V.2    Braciale, T.3
  • 37
    • 0022491834 scopus 로고
    • Fine specificity and antigen receptor expression among influenza virus-specific cytolytic T lymphocyte clones
    • Braciale, T., T. Henkel, A. Lukacher, and V. Braciale. 1986. Fine specificity and antigen receptor expression among influenza virus-specific cytolytic T lymphocyte clones. J. Immunol. 137(3):995-1002.
    • (1986) J. Immunol. , vol.137 , Issue.3 , pp. 995-1002
    • Braciale, T.1    Henkel, T.2    Lukacher, A.3    Braciale, V.4
  • 38
    • 0027340328 scopus 로고
    • Self-ignorance in the peripheral T-cell pool
    • Miller, J.F.A.P., and W. Heath. 1993. Self-ignorance in the peripheral T-cell pool. Immunol. Rev. 133:131-150.
    • (1993) Immunol. Rev. , vol.133 , pp. 131-150
    • Miller, J.F.A.P.1    Heath, W.2
  • 39
    • 0018835888 scopus 로고
    • Restriction specificities, alloreactivity, and allotolerance, expressed by T cells from nude mice reconstituted with H-2-compatible or -incompatible thymus grafts
    • Zinkernagel, R., A. Althage, E. Waterfield, B. Kindred, R. Welsh, G. Callahan, and P. Pincetl. 1980. Restriction specificities, alloreactivity, and allotolerance, expressed by T cells from nude mice reconstituted with H-2-compatible or -incompatible thymus grafts. J. Exp. Med. 151:376-399.
    • (1980) J. Exp. Med. , vol.151 , pp. 376-399
    • Zinkernagel, R.1    Althage, A.2    Waterfield, E.3    Kindred, B.4    Welsh, R.5    Callahan, G.6    Pincetl, P.7
  • 40
    • 0026845173 scopus 로고
    • Viral antigen presentation and MHC assembly
    • Braciale, T., and V. Braciale. 1992. Viral antigen presentation and MHC assembly. [Review]. Seminars Immunol. 4(2):81-4.
    • (1992) Seminars Immunol. , vol.4 , Issue.2 , pp. 81-84
    • Braciale, T.1    Braciale, V.2
  • 41
    • 0023162533 scopus 로고
    • Antigen presentation pathways to class I and class II MHC-restricted T lymphocytes
    • Braciale, T., L. Morrison, M. Sweetser, J. Sambrook, M. Gething, and V. Braciale. 1987. Antigen presentation pathways to class I and class II MHC-restricted T lymphocytes. [Review]. Immunol. Rev. 98(95):95-114.
    • (1987) Immunol. Rev. , vol.98 , Issue.95 , pp. 95-114
    • Braciale, T.1    Morrison, L.2    Sweetser, M.3    Sambrook, J.4    Gething, M.5    Braciale, V.6
  • 42
    • 0025019945 scopus 로고
    • Questions of presentation
    • Cresswell, P. 1990. Questions of presentation. Nature (Lond.). 343:593-594.
    • (1990) Nature (Lond.) , vol.343 , pp. 593-594
    • Cresswell, P.1
  • 43
    • 0025037001 scopus 로고
    • Characteristics of the tyrosine recognition signal for internalization of transmembrane surface glycoproteins
    • Ktistakis, N., D. Thomas, and M. Roth. 1990. Characteristics of the tyrosine recognition signal for internalization of transmembrane surface glycoproteins. J. Cell Biol. 111(4):1393-1407.
    • (1990) J. Cell Biol. , vol.111 , Issue.4 , pp. 1393-1407
    • Ktistakis, N.1    Thomas, D.2    Roth, M.3
  • 44
    • 0028017972 scopus 로고
    • Characteristics of the internalization signal in the Y543 influenza virus hemagglutinin suggest a model for recognition of internalization signals containing tyrosine
    • Naim, H., and M. Roth. 1994. Characteristics of the internalization signal in the Y543 influenza virus hemagglutinin suggest a model for recognition of internalization signals containing tyrosine. J. Biol. Chem. 269(6)3928-3933.
    • (1994) J. Biol. Chem. , vol.269 , Issue.6 , pp. 3928-3933
    • Naim, H.1    Roth, M.2
  • 45
    • 0027485028 scopus 로고
    • Response to influenza infection in mice with a targeted disruption in the interferon-gamma gene
    • Graham, M.B., D.K. Dalton, D. Giltinan, V. Braciale, T. Stewart, and T. Braciale. 1993. Response to influenza infection in mice with a targeted disruption in the interferon-gamma gene. J. Exp. Med. 178(5):1725-1732.
    • (1993) J. Exp. Med. , vol.178 , Issue.5 , pp. 1725-1732
    • Graham, M.B.1    Dalton, D.K.2    Giltinan, D.3    Braciale, V.4    Stewart, T.5    Braciale, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.