The biology of cortical granules

International Review of Cytology

Volumn 209, Issue , 2001, Pages 117-206

  Wessel, G M ^a   Brooks, J M ^a   Green, E ^a   Haley, S ^a   Voronina, E ^a   Wong, J ^a   Zaydfudim, V ^a   Conner, S ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

Cortical granule; Exocytosis; Fertilization; Protease activity; Protein interactions; Secretion; Signal transduction; SNARE model

Indexed keywords

ANIMAL CELL; CELL FUNCTION; CELL SECRETION; CELL VACUOLE; CONTROLLED STUDY; EXOCYTOSIS; FERTILIZATION; GRANULE CELL; MOLECULAR BIOLOGY; NONHUMAN; OOCYTE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN INTERACTION; REVIEW; SECRETION;

EID: 0034802126     PISSN: 00747696     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0074-7696(01)09012-X     Document Type: Review

References (408)

1. Incompetence of preovulatory mouse oocytes to undergo cortical granule exocytosis following induced calcium oscillations
2. On the ultrastructure of hyalin, a cell adhesion protein of the sea urchin embryo extracellular matrix
3. Sea urchin morphogenesis and cell-hyalin adhesion are perturbed by a monoclonal antibody specific for hyalin
4. Deployment of extracellular matrix proteins in sea urchin embryogenesis
5. Echinonectin: A new embryonic substrate adhesion protein
6. Immunocytochemical localization of the 35-kDa sea urchin egg trypsin-like protease and its effects upon the egg surface
7. Sulfated polysaccharides from the egg jelly layer are species-specific inducers of acrosomal reaction in sperms of sea urchins
8. Females of the sea urchin Strongylocentrotus purpuratus differ in the structures of their egg jelly sulfated fucans
9. Oocyte differentiation in the sea urchin, Arbacia punctulata, with particular reference to the origin of cortical granules and their participation in the cortical reaction
10. Comparative aspects of the ultrastructure of the female gamete
11. Immunocytochemical evidence suggesting heterogeneity in the population of sea urchin egg cortical granules
12. Rapid endocytosis coupled to exocytosis in adrenal chromaffin cells involves Ca2+, GTP, and dynamin but not clathrin
13. In vitro exocytosis in sea urchin eggs requires a synaptobrevin-related protein
14. NADPH oxidase: An update
15. The fine structure of human follicular oocytes
16. Molecular cloning of the first metazoan beta-1,3 glucanase from eggs of the sea urchin Strongylocentrotus purpuratus
17. A minimal binding domain of the low density lipoprotein receptor family
18. Enzymatic and envelope-converting activities of pars recta oviductal fluid from Xenopus laevis
19. Selective staining of the ultra-structural components of cortical granules and golgi cisternae of sea urchin eggs
20. Changes in the ultrastructure of amphibian eggs following fertilization
21. Translational control of cyclin B1 mRNA during meiotic maturation: Coordinated repression and cytoplasmic polyadenylation
22. Stimulation of NSF ATPase activity by alpha-SNAP is required for SNARE complex disassembly and exocytosis
23. The life cycle of the polycheate Nereis virens
24. Better late than never: A role for rabs late in exocytosis
25. The origin of human triploidy: An integration of qualitative and quantitative evidence
26. Reorganization of filamentous actin and myosin-II in zebrafish eggs correlates temporally and spatially with cortical granule exocytosis
27. Gamete and immune cell recognition revisited
28. Evidence for direct membrane retieval following cortical granule exocytosis in Xenopus oocytes and eggs
29. Intracellular signals trigger ultrastructural events characteristic of meiotic maturation in oocytes of Xenopus laevis
30. The molecular machinery for secretion is conserved from yeast to neurons
31. Cortical granules of the sea urchin translocate early in oocyte maturation
32. An extracellular matrix molecule that is selectively expressed during development is important for gastrulation in the sea urchin embryo
33. Fertilization induces endocytosis in Xenopus eggs
34. Identification and cloning of a glucan- and lipopolysaccharide-binding protein from Eisenia foetida earthworm involved in the activation of prophenoloxidase cascade
35. Calcium-regulated exocytosis is required for cell membrane resealing
36. Folding, calcium binding, and structural characterization of a concatemer of the first and second ligand-binding modules of the low-density lipoprotein receptor
37. Expression and disulfide-bond connectivity of the second ligand-binding repeat of the human LDL receptor
38. Fibropellins, products of an EGF repeat-containing gene, form a unique extracellular matrix structure that surrounds the sea urchin embryo
39. The SpEGF III gene encodes a member of the fibropellins: EGF repeat-containing proteins that form the apical lamina of the sea urchin embryo
40. Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25
41. Botulinum neurotoxin C1 blocks neurotransmitter release by means of cleaving HPC-1/syntaxin
42. Protein transport. A fusion of new ideas
43. Inhibition of neurotransmitter release by C2-domain peptides implicates synaptotagmin in exocytesis
44. Purification and analysis of Xenopus laevis cortical granule lectin and its ligand
45. The CUB domain. A widespread module in developmentally regulated proteins
46. Retrospective and prospective epidemiological studies of 1500 karyotyped spontaneous human abortions
47. The incidence of chromosomal abnormalities in frozen-thawed mouse oocytes after in-vitro fertilization
48. A receptor-mediated pathway for cholesterol homeostasis
49. Mature domestic cat oocyte does not express a cortical granule-free domain
50. Cortical granule proteases from sea urchin eggs
51. Isolation and biological activity of the proteases released by sea urchin eggs following fertilization
52. Characterization of primary amino acid sequence of human complement control protein factor I from an analysis of cDNA clones
53. Antral follicle development influences plasma membrane organization but not cortical granule distribution in mouse oocytes
54. Membrane fusion during secretion: Cortical granule exocytosis in sex urchin eggs as studied by quick-freezing and freeze-fracture
55. High molecular weight polymers block cortical granule exocytosis in sea urchin eggs at the level of granule matrix disassembly
56. Ca2+ regulates the interaction between synaptotagmin and syntaxin 1
57. A histochemical study of oogenesis in the sea urchin, Strongylocentrotus purpuratus
58. Role of the integrin-associated protein CD9 in binding between sperm ADAM 2 and the egg integrin alpha6betal: Implications for murine fertilization
59. Localization of cortical granule constituents before and after exocytosis in the hamster egg
60. Protein targeting to dense-core secretory granules
61. The hyaline layer: Its isolation and role in echinoderm development
62. Members of the SNARE hypothesis are associated with cortical granule exocytosis in the sea urchin egg
63. Rab3 mediates cortical granule exocytosis in the sea urchin egg
64. Syntaxin, VAMP, and Rab3 are selectively expressed during sea urchin embryogensis
65. Involvement of the cytoskeleton in the movement of cortical granules during oocyte maturation, and cortical granule anchoring in mouse eggs
66. Identification of the sorting signal motif within pro-opiomelanocortin for the regulated secretory pathway
67. Biochemical and functional studies of cortical vesicle fusion: The SNARE complex and Ca2+ sensitivity
68. In vitro reconstitution of exocytosis from plasma membrane and isolated secretory vesicles
69. Initiation of the cortical reaction in hamster and sheep oocytes in response to inositol trisphosphate
70. Cytoarchitecture of Caudiverbera caudiverbera stage VI oocytes: A light and electron microscope study
71. Three-dimensional structure of the second cysteine-rich repeat from the human low-density lipoprotein receptor
72. Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor
73. A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding
74. Developmental distribution of a cell surface glycoprotein in the sea urchin Strongylocentrotus purpuratus
75. Characterization of cortical secretory vesicles from the sea urchin egg
76. Purification and properties of ovoperoxidase, the enzyme responsible for hardening the fertilization membrane of the sea urchin egg
77. Observations sur le mecanisme et les phenomenes qui accompagnent la formaiton de l'embryon chezl'oursin comestible
78. Isolation and characterization of plasma membrane-associated cortical granules from sea urchin eggs
79. The effect on synaptic physiology of synaptotagmin mutations in Drosophila
80. Cortical granule exocytosis is coupled with membrane retrieval in the egg of Brachydanio
81. Incorporation of mouse zona pellucida proteins into the envelope of Xenopus laevis oocytes
82. Boar spermadhesin AWN-1. Oligosaccharide and zona pellucida binding characteristics
83. Interaction of non-aggregated boar AWN-1 and AQN-3 with phospholipid matrices. A model for coating of spermadhesins to the sperm surface
84. Attachment of the ascidian sperm surface egg receptor N-acetylglucosaminidase to the cell membrane
85. The family of guanylyl cyclase receptors and their ligands
86. The cortical reaction and development of activation competence in mammalian oocytes
87. Quantitalive studies of changes in cortical granule number and distribution in the mouse oocyte during meiotic maturation
88. A zona biochemical change and spontaneous cortical granule loss in eggs that fail to fertilize in in vitro fertilization
89. Quantification and localization of cortical granules during oogenesis in the mouse
90. Regulation of the polyspermy block in the mouse egg: Maturation-dependent differences in cortical granule exocytosis and zona pellucida modifications induced by inositol 1,4,5-trisphosphate and an activator of protein kinase C
91. Precocious loss of cortical granules during mouse oocyte meiotic maturation and correlation with an egg-induced modification of the zona pellucida
92. The development of mouse oocyte cortical reaction competence is accompanied by major changes in cortical vesicles and not cortical granule depth
93. Calmodulin activates NAD kinase of sea urchin eggs: An early event of fertilization
94. Methods for revoval of the vitelline membrane of sea urchin eggs. I. Use of dithiothreitol (Cleland Reagent)
95. Beta-1,3-glucanase of sea urchin eggs: Release from particles at fertilization
96. Coordinate expression of the three zona pellucida genes during mouse oogenesis
97. Cytoskeleton and polyploidy after maturation and fertilization of cryopreserved germinal vesicle-stage mouse oocytes
98. Alterations of the cytoskeleton and polyploidy induced by cryopreservation of metaphase II mouse oocytes
99. Fine structure of gametes of Nereis limbata (Annelida) before and after interaction
100. Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module
101. Identification of a minimal core of the synaptic SNARE complex sufficient for reversible assembly and disassembly
102. Conserved structural features of the synaptic fusion complex: SNARE proteins reclassified as Q- and R-SNAREs
103. Vesicle fusion from yeast to man
104. Three cell recognition changes accompany the ingression of sea urchin primary mesenchyme cells
105. Sea urchin egg cortical granule exocytosis is followed by a burst of membrane retrieval via uptake into coated vesicles
106. Fine structure of the bovine oocyte from the mature graafian follicle
107. O-linked oligosaccharides of mouse egg ZP3 account for its sperm receptor activity
108. Isolation of a protease from sea urchin eggs before and after fertilization
109. Release of ovoperoxidase from sea urchin eggs hardens the fertilization membrane with tyrosine crosslinks
110. Sperm-binding proteins
111. Receptor-mediated signal transduction and egg activation
112. Botulinum neurotoxin C1 cleaves both syntaxin and SNAP-25 in intact and permeabilized chromaffin cells: Correlation with its blockade of catecholamine release
113. Two distinct mechanisms control the accumulation of cyclin B1 and Mos in Xenopus oocytes in response to progesterone
114. Monoclonal antibodies to the sea urchin egg vitelline layer inhibit fertilization by blocking sperm adhesion
115. Follicle somatic cells influence pig oocyte penetrability and cortical granule distribution
116. Participation of a K(+) channel modulated directly by cGMP in the speract-induced signaling cascade of strongylocentrotus purpuratus sea urchin sperm
117. Molecular basis of fertilization
118. Guanylate cyclase receptor family
119. The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion
120. The vitelline envelope to fertilization envelope conversion in eggs of Xenopus laevis
121. Structure of the sea urchin hatching enzyme gene
122. Isolation and characterization of the vitelline layer of sea urchin eggs
123. Receptormediated endocytosis: Concepts emerging from the LDL receptor system
124. Peptides from sperm acrosomal protein that initiate egg development
125. Transient synthesis of a specific set of proteins during the rapid cleavage phase of sea urchin development
126. Formation and structure of the fertilization envelope in Xenopus laevis
127. The critical role of the MAP kinase pathway in meiosis II in Xenopus oocytes is mediated by p90(Rsk)
128. A monoclonal antibody that recognizes mammalian cortical granules and a 32-kilodalton protein in mouse eggs
129. Cortical granules of mammalian eggs
130. Recent progress in the structure, origin, composition, and function of cortical granules in animal egg
131. Studies on polyspermy in sea urchins
132. The cortical granule serine protease CGSPI of the sea urchin, Strongylocentrotus purpuratus, is autocatalytic and contains a low-density lipoprotein receptor-like domain
133. Hardening of the sea urchin fertilization envelope by peroxidase-catalyzed phenolic coupling of tyrosines
134. The apical lamina of the sea urchin embryo: Major glycoproteins associated with the hyaline layer
135. Conditions of oocyte storage and use of noninseminated as compared with inseminated, nonfertilized oocytes for the hemizona assay
136. All ras proteins are polyiso-prenylated but only some are palmitoylated
137. Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopy
138. The mechanism of membrane formation and other early changes in developing sea urchins' eggs as bearing on the problem of artificial parthenogenesis
139. Synaptic vesicle membrane fusion complex: Action of clostridial neurotoxins on assmbly
140. Bufo japonicus japonicus and Xenopus laevis egg jellies contain structurally related antigens and cortical granule lectin ligands
141. Differentiation of a calsequestrin-containing endoplasmic reticulum during sea urchin oogenesis
142. Structural changes after transmitter release at the frog neuromuscular junction
143. The 350-kDa sea urchin egg receptor for sperm is localized in the vitelline layer
144. Adrenal chromaffin cells contain functionally different SNAP-25 monomers and SNAP-25/syntaxin heterodimers
145. Calcium-induced dehiscence of cortical granules in Xenopus laevis oocytes
146. "Cleavage" and cortical granule breakdown in Rana pipins oocytes induced by direct microinjection of calcium
147. Relationship between p62 and p56, two proteins of the mammalian cortical granule envelope, and hyalin, the major component of the echinoderm hyaline layer, in hamsters
148. Mammalian cortical granules: Contents, fate, and function
149. The fine structure of the developing follice of the rhesus ovary
150. The fine structure of cortical granules in eggs and gastrulae of Mytilus edulis
151. Endotoxemia: Methods of detection and clinical correlates
152. The effect of local anesthetics and ammonia on cortical granule-plasma membrane attachment in the sea urchin egg
153. An ultrastructural immunocytochemical localization of hyalin in the sea urchin egg
154. SNAP-25 is essential for cortical granule exocytosis in mouse eggs
155. Diffrent requirements for NSF, SNAP, and Rab proteins in apical and basolateral transport in MDCK cells
156. The receptor-binding domain of human apolipoprotein E. Binding of apolipoprotein E fragments
157. Enhanced binding by cultured human fibroblasts of apo-E-containing lipoproteins as compared with low density lipoproteins
158. Follicle-stimulating hormone and growth hormone act differently on nuclear maturation while both enhance developmental competence of in vitro matured bovine oocytes
159. Messenger RNA expression and protein localization of growth hormone in bovine ovarian tissue and in cumulus oocyte complexes (COCs) during in vitro maturation
160. Mild proteolytic digestion restores exocytotic activity to N-ethylmaleimide-inactivated cell surface complex from sea urchin eggs
161. The origin of human triploids
162. Egg Membranes during fertilization
163. Secl/Munc 18 proteins: Mediators of membrane fusion moving to center stage
164. Membrane fusion. SNAREs line up in new environment
165. Membrane fusion and exocytosis
166. Evidence for a functional link between Rab3 and the SNARE complex
167. The influence of cooling on the properties of the zona pellucida of the mouse oocyte
168. Cloning and sequencing of full-length cDNA encoding the precursor of human complement component Clr
169. The fertilization reaction in Echinarachnius parma I. Cortical response of egg to insemination
170. Reexamination of the sequence of the sea urchin egg receptor for sperm: Implications with respect to its properties
171. A rapidly diverging EGF protein regulates species-specific signal transduction in early sea urchin development
172. Direct isolation of the hyaline layer protein released from the cortical granules of the sea urchin egg at fertilization
173. Hyalin release during normal sea urchin development and its replacement after removal at fertilization
174. Acid mucopolysaccharide metabolism, the cell surface, and primary mesenchyme cell activity in the sea urchin embryo
175. Molecular cloning of Xenopus hatching enzyme and its specific expression in hatching gland cells
176. Ovoperoxidase assembly into the sea urchin fertilization envelope and dityrosine crosslinking
177. Localization of synaptotagmin-binding domains on syntaxin
178. Neural transmission. Synaptotagmin is just a calcium sensor
179. Cortical changes in growing oocytes and in fertilized or pricked eggs of Rana pipiens
180. Cloning and chromosomal mapping of a gene isolated from thymic stromal cells encoding a new mouse type II membrane serine protease, epithin, containing four LDL receptor modules and two CUB domains
181. Purification and properties of the egg plasma membrane
182. Enterokinase, the initiator of intestinal digestion, is a mosaic protease composed of a distinctive assortment of domains
183. Characterization of the hatching enzyme from embryos of an anuran amphibian, Rana pirica
184. The occurrence of novel 9-O-sulfated N-glycolyneuraminic acid-capped alpha2→5-Oglycolyl-linked oligo/polyNeu5Gc chains in sea urchin egg cell surface glycoprotein. Identification of a new chain termination signal for polysialyltransferase
185. Metabolic similarities between fertilization and phagocytosis. Conservation of a peroxidatic mechanism
186. Priming in exocytosis: Attaining fusion-competence after vesicle docking
187. The timing of cortical granule fusion, content dispersal, and endocytosis during fertilization of the hamster egg: An electrophysiological and histochemical study
188. Trafficking of lysosomal enzymes
189. Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein
190. Electron microscopic studies of the structure of the oocyte and the 2-cell stage in the rabbit. I. Oocyte
191. Electron microscopic studies of the structure of the oocyte and the 2-cell stage in the rabbit. II. Blastomeres
192. A major glycoprotein of Xenopus egg vitelline envelope, gp41, is a frog homolog of mammalian ZP3
193. The Xenopus IP3 receptor: Structure, function, and localization in oocytes and eggs
194. NO is necessary and sufficient for egg activation at fertilization
195. A survey of GTP-binding proteins and other potential key regulators of exocytotic secretion in eosinophils
196. Sea urchin ovoperoxidase: Oocyte-specific member of a heme-dependent peroxidase superfamily that functions in the block to polyspermy
197. Cortical granule biogenesis is active throughout oogenesis in sea urchins
198. Ascidian eggs block polyspermy by two independent mechanism: One at the egg plasma membrane, the other involving the follicle cells
199. Ascidian eggs release glycosidase activity which aids in the block against polyspermy
200. Glycolipid linkage of a polyspermy blocking glycosidase to the ascidian egg surface
201. Fertilization-induced changes in the vitelline envelope of echinoderm and amphibian eggs: Self-assembly of an extracellular matrix
202. Freeze-fracture analysis of structural reorganization during meiotic maturation in oocytes of Xenopus laevis
203. In vitro formation of the "S" layer, a unique component of the fertilization envelope in Xenopus laevis eggs
204. Fluorescent in-situ hybridization on human embryos showing cleavage arrest after freezing and thawing
205. Characterization of a calsequestrin-like protein from sea-urchin eggs
206. Purification and characterization of the sea urchin embryo hatching enzyme
207. Spatial expression of the hatching enzyme gene in the sea urchin embryo
208. Distinct Ca2+ and Sr2+ binding properties of synaptotagmins. Definition of candidate Ca2+ sensors for the fast and slow components of neurotransmitter release
209. FIGalpha, a germ cell specific transcription factor involved in the coordinate expression of the zona pellucida genes
210. Oocyte-specific expression of mouse Zp-2: Developmental regulation of the zona pellucida genes
211. Conservation of mammalian secondary sperm receptor genes enables the promoter of the human gene to function in mouse oocytes
212. Studies of fertilization in Nereis. I The cortical changes in the egg. II. Partial fertilization
213. Isolation and characterization of ovochymase, a chymotrypsinlike protease released during Xenopous laevis egg activation
214. Ovochymase, a Xenopus laevis egg extracellular protease, is translated as part of an unusual polyprotease
215. Targeted disruption of the mZP3 gene results in production of eggs lacking a zona pellucida and infertility in female mice
216. A cytological study of the relation of the cortical reaction to subsequent events of fertilization in urethane-treated eggs of the sea urchin Arbacia punctulata
217. Fine structure of the mammalian egg cortex
218. Cortical changes in starfish (Asterina pectinifera) oocytes during 1-methyladenine-induced maturation and fertilisation/activation
219. The SNARE machinery is involved in apical plasma membrane trafficking in MDCK cells
220. t-SNARE activation through transient interaction with a rab-like guanosine triphosphatase
221. Ultrastructure and morphometric observations of cortical endoplasmic reticulum in Arbacia, Spisula and mouse eggs
222. Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
223. Rab proteins
224. Studies on the annual reproductive cycle of the sea urchin and the acid phosphatase of relict ova
225. Expression of Rab3A in the cortical region in mouse metaphase II eggs
226. Involvement of Rabphilin-3A in cortical granule exocytosis in mouse eggs
227. Cortical granule exocytosis is triggered by different thresholds of calcium during fertilisation in sea urchin eggs
228. Identification of a 97-kDa heat shock protein from S. franciscanus ovaries with 94% amino acid identity to the S. purpuratus egg surface receptor for sperm
229. Sea urchin hyalin: Appearance and function in development
230. Patching plasma membrane disruptions with cytoplasmic membrane
231. Endocytosis and molecular sorting
232. Phosphorylation of CPE binding factor by Eg2 regulates translation of c-mos mRNA
233. Positive selection and sequence rearrangements generate extensive polymorphism in the gamete recognition protein bindin
234. Oocyte-specific factors bind a conserved upstream sequence required for mouse zona pellucida promoter activity
235. Normal fertilization occurs with eggs lacking the integrin alpha6betal and is CD9-dependent
236. Egg cortical granule N-acetyl-glucosaminidase is required for the mouse zona block to polyspermy
237. Complementarity between sperm surface beta-1,4-galactosyltransferse and egg-coat ZP3 mediates sperm-egg binding
238. Requirement of CD9 on the egg plasma membrane for fertilization
239. Localization and functional role of synaptotagmin III in insulin secretory vesicles in pancreatic beta-cells
240. Trafficking/sorting and granule biogenesis in the beta-cell
241. Characterization of a proteinase that cleaves zona pellucida glycoprotein ZP2 following activation of mouse eggs
242. Bacterial protein toxins and cell vesicle trafficking
243. Structure and function of tetanus and botulinum neurotoxins
244. Identification of an abl-related protein tyrosine kinase in the cortex of the sea urchin egg: Possible role at fertilization
245. Materials of the fertilization membrane in the eggs of Echinoderms
246. Ultrastructure of the proteoliaisin-ovoperoxidase complex and its spatial organization within the Strongylocentrotus purpuratus fertilization envelope
247. Purification and properties of an exo-beta-D-1,3-glucanase from sea urchin eggs
248. Primary structure of the human heparan sulfate protoeglycan from basement membrane (HSPG2/perlecan). A chimeric molecule with multiple domains homologous to the low density lipoprotein receptor, laminin, neural cell adhesion molecules, and epidermal growth factor
249. The alphaBbetaC integrin is expressed on the surface of the sea urchin egg and removed at fertilization
250. Horseshoe crab factor G: A new heterodimeric serine protease zymogen sensitive to (1 → 3)-beta-D-glucan
251. Micropinocytotic origin of coated and smooth microvesicles ("synaptic vesicles") in neurosecretory terminals of posterior pituitary glands demonstrated by incorporation of horseradish peroxidase
252. Cell polarity in sea urchin embryos: Reorientation of cells occurs quickly in aggregates
253. Homotypic vacuolar fusion mediated by t- and v-SNAREs
254. Cumuli oophori in tissue culture: Hormone production, ultrastructure, and morphometry of early luteinization
255. Cortical granule distribution and cell surface characteristics in mouse eggs
256. Proteins of the sea urchin egg vitelline layer
257. Real-time measurements of the interactions between fluorescent speract and its sperm receptor
258. Isolation and characterization of a lectin from the cortical granules of Xenopus laevis eggs
259. Acetylcholine activates intracellular movement of insulin granules in pancreatic beta-cells via inositol trisphosphate-dependent [correction of triphosphate-dependent] mobilization of intracellular Ca2+
260. The primary and higher order structures of sea urchin ovoperoxidase as determined by cDNA cloning and predicted by homology modeling
261. Sea urchin hatching enzyme (envelysin): Cdna cloning and deprivation of protein substrate specificity by autolytic degradation
262. Sea urchin ovoperoxidase: Solubilization and isolation from the fertilization envelope, some structural and functional properties, and degradation by hatching enzyme
263. The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule
264. Membrane retrieval following exocytosis in isolated neurosecretory nerve endings
265. A pattern-recognition protein for beta-1,3-glucan. The binding domain and the cDNA cloning of beta-1,3-glucan recognition protein from the silkworm, Bombyx mori
266. Primary structure of a 120 kDa protein associated with the fucose sulfate glycoconjugate constituting the acrosome reaction-inducing substance of the sea urchin, Hemicentrotus pulcherrimus
267. Role of the sea urchin egg receptor for sperm in gamete interactions
268. The biologically active form of the sea urchin egg receptor for sperm is a disulfide-bonded homo-multimer
269. Spontaneous cortical granule release and alteration of zona pellucida properties during and after meiotic maturation of mouse oocytes
270. Structural basis of Rab effector specificity: Crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A
271. Assembly and disassembly of a ternary complex of synaptobrevin, syntaxin, and SNAP-25 in the membrane of synaptic vesicles
272. All males are not created equal: Fertility differences depend on gamete recognition polymorphisms in sea urchins
273. Electron microscope study of the cortical reaction. I. The cortical fertilization reaction in Paracentrotus and its chronology. II. The cortical reaction in the unfertilized egg of Sabellaria alveolata
274. Rab GDP dissociation inhibitor: Putting rab GTPases in the right place
275. Characterization and localization of a mouse egg cortical granule antigen prior to and following fertilization or egg activation
276. Thirty years of stimulus-secretion coupling: From Ca(2+) to GTP in the regulation of exocytosis
277. Protease resistance of synataxin. SNAP-25. VAMP complexes. Implications for assembly and structure
278. The synaptic SNARE complex is a parallel four-stranded helical bundle
279. Purification and characterization of an N-acetyl-beta-D-glucosaminidase from cortical granules of Xenopus laevis eggs
280. The oligomeric state of 46-kDa mannose 6-phosphate receptor does not change upon intracellular recycling and binding of ligands
281. The fertilization layer mediated block to polyspermy in Xenopus laevis: Isolation of the cortical granule lectin ligand
282. The zona pellucida: Using molecular genetics to study the mammalian egg coat
283. Mice homozygous for an insertional mutation in the Zp3 gene lack a zona pellucida and are infertile
284. Segregation of the pathways leading to cortical reaction and cell cycle activation in the rat egg
285. Mechanisms leading to cortical reaction in the mammalian egg
286. Identification and partial characterization of yolk and cortical granule proteins in eggs and embryos of the starfish, Pisaster ochraceus
287. Early mRNAs, spatially restricted along the animal-vegetal axis of sea urchin embryos, include one encoding a protein related to tolloid and BMP-1
288. Biosynthesis and secretion of the hatching enzyme during sea urchin embryogenesis
289. Crystal structure of acidic seminal fluid protein (aSFP) at 1.9 A resolution: A bovine polypeptide of the spermadhesin family
290. Implications of the SNARE hypothesis for intracellular membrane topology and dynamics
291. Protein sorting by transport vesicles
292. Calcium release at fertilization of Xenopus eggs requires type I IP(3) receptors, but not SH2 domain-mediated activation of PLCgamma or G(q)-mediated activation of PLCbeta
293. The vitelline membrane and cortical particles in sea urchin eggs and their function in maturation and fertilization
294. Different combinations of cysteine-rich repeats mediate binding of low density lipoprotein receptor to two different proteins
295. Influence of cytochalasin B on oocyte maturation in Xenopus laevis
296. GTPase activity of Rab5 acts as a timer for endocytic membrane fusion
297. In vivo cleavage rates and viability obtained for early cleavage mouse embryos in co-culture with oviduct cells
298. Cortical granule translocation during maturation of starfish oocytes requires cytoskeletal rerrangement triggered by InsP3-mediated Ca2+ release
299. Boar spermadhesins AQN-1 and AWN are sperm-associated acrosin inhibitor acceptor proteins
300. Isolation and biochemical characterization of heparin-binding proteins from boar seminal plasma: A dual role for spermadhesins in fertilization
301. The ultrastructure of the sea urchin egg cortex isolated before and after fertilization
302. Tyrosine kinase-dependent activation of phospholipase cgamma is required for calcium transient in xenopus egg fertilization
303. Purification and characterization of trypsin-like enzyme from sea urchin eggs: Substrate specificity and physiological role
304. Evidence that the ability to respond to a calcium stimulus in exocytosis is determined by the secretory granule membrane: Comparison of exocytosis of injected bovine chromaffin granule membranes and endogenous cortical granules in Xenopus laevis oocytes
305. Intracellular targets and metalloprotease activity of tetanus and botulism neurotoxins
306. Botulinum neurotoxin type C cleaves a single Lys-Ala bond within the carboxyl-terminal region of syntaxins
307. Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses
308. Rab GTPases, directors of vesicle docking
309. Mammalian sperm-egg recognition and binding in vitro. I. Specificity of sperm interactions with live and fixed eggs in homologous and heterologous inseminations of hamster, mouse, and guinea pig oocytes
310. Surface area change at fertilization: Resorption of the mosaic membrane
311. Secretory functions of egg cortical granules
312. Sulfated acid mucopolysaccharides in the cortical granules of eggs. Effects of quaternary ammonium salts on fertilization
313. A trypsin-like proteinase localized in cortical granules isolated from unfertilized sea urchin eggs by zonal centrifugation. Role of the enzyme in fertilization
314. Molecular basis of mammalian egg activation
315. Apolipoprotein B and low-density lipoprotein structure: Implications for biosynthesis of triglyceride-rich lipoproteins
316. Genetic analysis of neurotransmitter release at the synapse
317. Horseshoe crab (1,3)-beta-D-glucan-sensitive coagulation factor G. A serine protease zymogen heterodimer with similarities to beta-glucan-binding proteins
318. The formation and cytochemical characterization of cortical granules in ovarian oocytes of the golden hamster (Mesocricetus auratus)
319. The control of oxidant stress at fertilization
320. Extracellular remodeling during fertilization
321. Mechanisms of calcium regulation in sea urchin eggs and their activities during fertilization
322. Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP-binding protein related to synaptotagmin
323. Expression of the vitellogenin gene in female and male sea urchin
324. Exocytotic insertion of calcium channels constrains compensatory endocytosis to sites of exocytosis
325. A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles
326. Localization and developmental fate of ovoperoxidase and proteoliaisin, two proteins involved in fertilization envelope assembly
327. Functional domains of proteoliaisin, the adhesive protein that orchestrates fertilization envelope assembly
328. G protein mechanisms: Insights from structural analysis
329. Cell membrane resealing by a vesicular mechanism similar to neurotransmitter release
330. Comparative biology of calcium signaling during fertilization and egg activation in animals
331. Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution
332. Development of cortical granules and the cortical reaction in rat and hamster eggs
333. On the role of gap junctions between follicle cells and oocyte in the mammalian ovarian follicle
334. SNAP-25 is present on chromaffin granules and acts as a SNAP receptor
335. Syntaxin 1 (HPC-1) is associated with chromaffin granules
336. Calcium can disrupt the SNARE protein complex on sea urchin egg secretory vesicles without irreversibly blocking fusion
337. The purification and characterization of an exo-beta (1 going to 3)-glucanohydrolase from sea urchin eggs
338. Visualization of exocytosis during sea urchin egg fertilization using confocal microscopy
339. Characterization of sea urchin egg endoplasmic reticulum in cortical preparations
340. Organization of the sea urchin egg endoplasmic reticulum and its reorganization at fertilization
341. DbClustal: Rapid and reliable global multiple alignments of protein sequences detected by database searches
342. Xenopus laevis sperm receptor gp69/64 glycoprotein is a homolog of the mammalian sperm receptor ZP2
343. Gamete interactions in Xenopus laevis: Identification of sperm binding glycoproteins in the egg vitelline envelope
344. Xenopus laevis sperm-egg adhesion is regulated by modifications in the sperm receptor and the egg vitelline envelope
345. Biogenesis of secretory granules
346. Spermadhesins: A new protein family. Facts, hypotheses and perspectives
347. Stage-specific expression of beta-1,3-glucanase in sea urchin embryos and hybrids
348. Ca2+ binding to synaptotagmin: How many Ca2+ ions bind to the tip of a C2-domain?
349. A vacuolar v-t-SNARE complex, the predominant form in vivo and on isolated vacuoles, is disassembled and activated for docking and fusion
350. The use of radioiodinated protein substrates for the assay of trypsin and the hatching enzyme from the amphibian Xenopus laevis
351. The appearance of beta-1,3-glucanase in hatching embryos of the sea urchin, Echinometra vanbrunti
352. The isolation of intact cortical granules from sea urchin eggs: Calcium ions trigger granule discharge
353. Isolated cortical granules: A model system for studying membrane fusion and calcium-mediated exocytosis
354. Isolation of bindin: The protein responsible for adhesion of sperm to sea urchin eggs
355. The fucose sulfate polymer of egg jelly binds to sperm REJ and is the inducer of the sea urchin sperm acrosome reaction
356. Protease activity establishes the block against polyspermy in sea urchin eggs
357. Protease released from sea urchin eggs at fertilization alters the vitelline layer and aids in preventing polyspermy
358. The 2.4 A resolution crystal structure of boar seminal plasma PSP-I/PSP-II: A zona pellucida-binding glycoprotein heterodimer of the spermadhesin family built by a CUB domain architecture
359. Purification and characterization of a cortical secretory vesicle membrane fraction
360. Fine structural changes during sea urchin oogenesis
361. Structure of the sulfated alpha-L-fucan from the egg jelly coat of the sea urchin Strongylocentrotus franciscanus: Patterns of preferential 2-O- and 4-O-sulfation determine sperm cell recognition
362. Independent and hetero-oligomeric-dependent sperm binding to egg envelope glycoprotein ZPC in Xenopus laevis
363. The sea urchin cortical reaction. A model system for studying the final steps of calcium-triggered vesicle fusion
364. Calcium influx is required for endocytotic membrane retrieval
365. Identification and cloning of the membrane-associated serine protease, hepsin, from mouse preimplantation embryos
366. Isolation of plasma membrane complexes from Xenopus oocytes
367. Ultrastructural aspects of oogenesis and oocyte growth in fish and amphibians
368. Mutational analysis of SEC4 suggests a cyclical mechanism for the regulation of vesicular traffic
369. Development of the competence of bovine oocytes to release cortical granules and block polyspermy after meiotic maturation
370. Beobachtungen uber die oxydationsprozesse im seeigelei
371. Botulinum neurotoxin types A and E require the SNARE motif in SNAP-25 for proteolysis
372. Mammalian fertilization: Molecular aspects of gamete adhesion, exocytosis, and fusion
373. The mouse egg's receptor for sperm: What is it and how does it work?
374. SNAREpins: Minimal machinery for membrane fusion
375. Assembly of the sea urchin fertilization membrane: Isolation of proteoliaisin, a calcium-dependent ovoperoxidase binding protein
376. Membrane fusion. SNARE the rod, coil the complex
377. Apolipoprotein E: Structure-function relationships
378. The receptor-binding domain of human apolipoprotein E. Monoclonal antibody inhibition of binding
379. Cortical granule-specific components are present within oocytes and accessory cells during sea urchin oogenesis
380. A protein of the sea urchin cortical granules is targeted to the fertilization envelope and contains an LDL-receptor-like motif
381. A molecular analysis of hyalin - A substrate for cell adhesion in the hyaline layer of the sea urchin embryo
382. SFE1, a constituent of the fertilization envelope in the sea urchin is made by oocytes and contains low-density lipoprotein-receptor-like repeats
383. Ontogeny of the basal lamina in the sea urchin embryo
384. A cortical granule-specific enzyme, B-1,3-glucanase, in sea urchin eggs
385. Direct membrane retrieval into large vesicles after exocytosis in sea urchin eggs
386. Exocytosis reconstituted from the sea urchin egg is unaffected by calcium pretreatment of granules and plasma membrane
387. Exocytosis in sea urchin eggs
388. Lighting the fuse at fertilization
389. Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E
390. Changes in the organization of the sea urchin egg plasma membrane upon fertilization: Indications from the lateral diffusion rates of lipid-soluble fluorescent dyes
391. The cortical granule reaction in living eggs of the toad, Xenopus laevis
392. On the contents of the cortical granules from Xenopus laevis eggs
393. Isolation, physicochemical properties, and the macromolecular composition of the vitelline and fertilization envelopes from Xenopus laevis eggs
394. Vesicle transport: More work for the Rabs?
395. Agglutination of jelly coat and cortical granule components and the block to polyspermy in the amphibian Xenopus laevis
396. Two constituent proteases of a teleostean hatching enzyme: Concurrent syntheses and packaging in the same secretory granules in discrete arrangement
397. Isolation of cDNAs for LCE and HCE, two constituent proteases of the hatching enzyme of Oryzias latipes, and concurrent expression of their mRNAs during development
398. Immunological analysis of the calcium precipitable protein of sea urchin eggs. (1) Hyaline layer substance
399. The macromolecular composition of Xenopus laevis egg jelly coat
400. Rab GTPases in vesicular transport
401. Comparison of ZP3 protein sequences among vertebrate species: To obtain a consensus sequence for immunocontraception
402. Are mechanisms of exocytosis neurotransmitter specific?