Four-jointed interacts with dachs, abelson and enabled and feeds back onto the Notch pathway to affect growth and segmentation in the Drosophila leg

Development

Volumn 128, Issue 18, 2001, Pages 3533-3542

  Buckles, G R ^a   Rauskolb, C ^a   Villano, J L ^a   Katz, F N ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Abelson; Dachs; Delta; Drosophila melanogaster; Enabled; Four jointed; Leg segmentation; Serrate

Indexed keywords

ABELSON PROTEIN; ACTIN; DACHS PROTEIN; ENABLED PROTEIN; FOUR JOINTED PROTEIN; GENE PRODUCT; JAGGED1; LIGAND; MEMBRANE PROTEIN; NOTCH RECEPTOR; ONCOPROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BODY REGIONS; CONTROLLED STUDY; CYTOSKELETON; DROSOPHILA; GENE TARGETING; IN VIVO STUDY; LEG; LIMB DEVELOPMENT; MOLECULAR BIOLOGY; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION;

ANIMALS; BODY PATTERNING; CALCIUM-BINDING PROTEINS; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EXTREMITIES; FEEDBACK; INSECT PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; JOINTS; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; NUCLEAR PROTEINS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 0034796869     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (62)

1. Notch signaling: Cell fate control and signal intergration in development
2. fjx1, the murine homologue of the Drosophila four-jointed gene, codes for a putative secreted protein expressed in restricted domains of the developing and adult brain
3. The EVH2 domain of the vasodilator-stimulated phosphoprotein mediates tetramerization, F-actin binding, and actin bundle formation
4. Dissection of cis-regulatory elements of the Drosophila gene Serrate
5. Negative regulation of fibroblast motility by Ena/VASP proteins
6. Composite signalling from Serrate and Delta establishes leg segments in Drosophila through Notch
7. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
8. Positional information along the dorsal-ventral axis of the Drosophila eye: Graded expression of the four-jointed gene
9. Organizing spatial pattern in limb development
10. Proximo-distal specification in the wing disc of Drosophila by the nubbin gene
11. Proximo-distal development in the legs of Drosophila
12. Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing
13. Notch signaling mediates segmentation of the Drosophila leg
14. Planar polarity in Drosophila and vertebrate epithelia
15. The FlyBase database of the Drosophila genome projects and community literature
16. The metamorphic development of the adult epidermis
17. Genetic suppression of mutations in the Drosophila abl proto-oncogene homolog
18. Enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties
19. Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics
20. Extra tarsal joints and abnormal cuticular polarities in various mutants of Drosophila melanogaster
21. DNA sequence, structure, and tyrosine kinase activity of the Drosophila melanogaster Abelson proto-oncogene homolog
22. A novel tyrosine kinase independent function of Drosophila abl correlates with proper subcellular localization
23. The basic helix-loop-helix domain of Drosophila Lethal of Scute protein is sufficient for proneural function and activates neurogenic genes
24. Drosophila Abl and genetic redundancy in signal transduction
25. Preparation and analysis of membranes and membrane proteins from Drosophila
26. Fringe, Notch, and making developmental boundaries
27. The Drosophila mushroom body is a quadruple structure of clonal units each of which contains a virtually identical set of neurones and glial cells
28. Analysis of the gene encoding the largest subunit of RNA polymerase II in Drosophila
29. The AP-2 transcription factor is required for joint formation and cell survival in Drosophila leg development
30. From the growth cone surface to the cytoskeleton: One journey, many paths
31. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
32. From Abl to actin: Abl tyrosine kinase and associated proteins in growth cone motility
33. Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport
34. Membrane-anchored growth factors
35. Activation of tyrosine kinase and microfilament-binding functions of c-Abl by Bcr sequences in Bcr/Abl fusion proteins
36. The function and regulation of cut expression on the wing margin of Drosophila: Notch, Wingless and a dominant negative role for Delta and Serrate
37. Planar polarity in the Drosophila eye: A multifaceted view of signaling specificity and cross-talk
38. Decapentaplegic overexpression affects Drosophila wing and leg imaginal disc development and wingless expression
39. A hierarchy of cross-regulation involving Notch, wingless, vestigial, and cut organizes, the dorsal/ventral axis of the Drosophila wing
40. Modulators of Notch signaling
41. Dorsal-ventral signaling in the Drosophila eye
42. The pleiotropic function of Delta during postembryonic development of Drosophila melanogaster
43. Vectors for P-mediated transformation in Drosophila
44. C-Abl is activated by growth factors and src family kinases and has a role in the cellular response to PDGF
45. Notch-mediated segmentation and growth control of the Drosophila leg
46. The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins
47. Cell lines derived from the late embryonic stages of Drosophila melanogaster
48. ts1, a conditional Notch lethal in Drosophila
49. The Serrate locus of Drosophila and its role in morphogenesis of the wing imaginal discs: Control of cell proliferation
50. P element-mediated transformation
51. Specificity of bone morphogenetic protein (BMP) related factors: Cell fate and gene expression changes in Drosophila embryos induced by decapentaplegic but not 60A
52. Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo
53. The effect of growth and joint formation on bristle pattern in D. melanogaster
54. Directed actin polymerization is the driving force for epithelial cell-cell adhesion
55. Four-jointed is required for intermediate growth in the proximal-distal axis in Drosophila
56. The development of some 'leg genes' in Drosophila
57. Abl tyrosine kinase in signal transduction and cell-cycle regulation
58. The four-jointed gene is required in the Drosophila eye for ommatidial polarity specification
59. Multiple roles for four-jointed in planar polarity and limb patterning