CCAAT/enhancer binding protein α assembles essential cooperating factors in common subnuclear domains

Molecular Endocrinology

Volumn 15, Issue 10, 2001, Pages 1665-1676

  Schaufele, Fred ^a   Enwright III, John F ^b   Wang, Xia ^a   Teoh, Cheryl ^a   Srihari, Roopali ^a   Erickson, Robin ^c   Macdougald, Ormond A ^c   Day, Richard N ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NATIONAL SCIENCE FOUNDATION   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; GROWTH HORMONE;

ANIMAL CELL; ARTICLE; CHROMATIN; DNA BINDING; GENE EXPRESSION REGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION;

3T3 CELLS; ANIMALS; BINDING SITES; BIOLOGICAL TRANSPORT; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CELL LINE; CELL NUCLEUS; CENTROMERE; CHROMATIN; CREB-BINDING PROTEIN; DNA-BINDING PROTEINS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; GROWTH HORMONE; LUMINESCENT PROTEINS; MICE; NUCLEAR PROTEINS; PITUITARY GLAND; PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; STEM CELLS; TATA-BOX BINDING PROTEIN; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0034785786     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.15.10.1665     Document Type: Article

References (62)

1. C/EBP α: A critical regulator of genes governing integrative metabolic processes
2. Is CCAAT/enhancer-binding protein a central regulator of energy metabolism?
3. The C/EBP family of transcription factors
4. Antisense CCAAT/enhancer-binding protein RNA suppresses coordinate gene expression and triglyceride accumulation during differentiation of 3T3-L1 preadipocytes
5. Increased hepatic cell proliferation and lung abnormalities in mice deficient in CCAAT/enhancer binding protein α
6. Role of the isoforms of CCAAT/enhancer-binding protein in the initiation of phosphoenolpyruvate carboxykinase (GTP) gene transcription at birth
7. The role of C/EBP genes in adipocyte differentiation
8. Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein α-deficient mice
9. CCAAT/enhancer binding protein α is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors
10. Expression of CCAAT enhancer binding protein-alpha (C/EBP α) in the rat ovary: Implications for follicular development and ovulation
11. Resolution by diagonal gel mobility shift assays of multisubunit complexes binding to a functionally important element of the rat growth hormone gene promoter
12. CCAAT/enhancer-binding protein α activation of the rat growth hormone promoter in pituitary progenitor GHFT1-5 cells
13. GHF-1-promoter-targeted immortalization of a somatotropic progenitor cell results in dwarfism in transgenic mice
14. CCAAT/enhancer binding protein α is sufficient to initiate the 3T3-L1 adipocyte differentiation program
15. Activation and centromeric localization of CCAAT/enhancer-binding proteins during the mitotic clonal expansion of adipocyte differentiation
16. Regulation of the growth hormone and prolactin genes
17. Transcriptional mechanisms in anterior pituitary cell differentiation
18. Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1
19. An "attenuator domain" is sandwiched by two distinct transactivation domains in the transcription factor C/EBP
20. CCAAT/enhancer binding protein-α amino acid motifs with dual TBP and TFIIB binding ability co-operate to activate transcription in both yeast and mammalian cells
21. The ability of C/EBPβ but not C/EBPα to synergize with an Sp1 protein is specified by the leucine zipper and activation domain
22. p300 coactivates the adipogenic transcription factor CCAAT/enhancer-binding protein
23. Signal-specific co-activator domain requirements for Pit-1 activation
24. Interaction and functional collaboration of p300 and C/EBPβ
25. CREB binding protein coordinates the function of multiple transcription factors including nuclear factor 1 to regulate phosphoenolpyruvate carboxykinase (GTP) gene transcription
26. Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated protein p300
27. Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP
28. Activities in Pit-1 determine whether receptor interacting protein 140 activates or inhibits Pit-1/nuclear receptor transcriptional synergy
29. Temporally distinct and ligand-specific recruitment of nuclear receptor interacting peptides and co-factors to subnuclear domains containing the estrogen receptor
30. Subnuclear trafficking of estrogen receptor-α and steroid receptor coactivator-1
31. Three distinct sub-nuclear populations of HMG-1 protein of different properties revealed by co-localization image analysis
32. 5-Methylcytosine localized in mammalian constitutive heterochromatin
33. Mouse centromeric heterochromatin: Isolation and some characteristics
34. Simplified and optimized kinetochore detection: Cytogenetic marker for late-G2 cells
35. Positions of potential: Nuclear organization and gene expression
36. Regional and temporal specialization in the nucleus: A transcriptionally-active nuclear domain rich in PTF, Oct1 and PIKA antigens associates with specific chromosomes early in the cell cycle
37. Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body
38. Phosphorylated CREB binds specifically to the nuclear protein CBP
39. Two-color green fluorescent protein time-lapse imaging
40. Dual-colour imaging with GFP variants
41. Visualization of Pit-1 transcription factor interactions in the living cell nucleus by fluorescence resonance energy transfer microscopy
42. Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
43. The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways
44. Multiple signal input and output domains of the 160-kilodalton nuclear receptor coactivator proteins
45. The organization of replication and transcription
46. Intranuclear targeting of AML/CBFα regulatory factors to nuclear matrix-associated transcriptional domains
47. Nuclear matrix association of multiple sequence-specific DNA binding activities related to SP-1, ATF, CCAAT, C/EBP, OCT-1, and AP-1
48. Association of transcription factors with the nuclear matrix
49. A soluble transcription factor, Oct-1, is also found in the insoluble nuclear matrix and possesses silencing activity in its alanine-rich domain
50. Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division
51. Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin
52. Structure and dynamic organization of centromeres/prekinetochores in the nucleus of mammalian cells
53. Localization of a putative transcriptional regulator (ATRX) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes
54. The distribution of polycomb-group proteins during cell division and development in Drosophila embryos: Impact on models for silencing
55. The human polycomb group complex associates with pericentromeric heterochromatin to form a novel nuclear domain
56. Virus induction of human IFNβ gene expression requires the assembly of an enhanceosome
57. The mechanism of transcriptional synergy of an in vitro assembled interferon-β enhanceosome
58. Recruitment of CBP/p300 by the IFNβ enhanceosome is required for synergistic activation of transcription
59. Acetylation of HMGI(Y) by CBP turns off IFNβ expression by disrupting the enhanceosome
60. Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer
61. Amplification methods to increase the sensitivity of in situ hybridization
62. Visualizing protein-protein interactions in the nucleus of the living cell