Chlamydia trachomatis-induced apoptosis occurs in uninfected McCoy cells late in the developmental cycle and is regulated by the intracellular redox state

Microbial Pathogenesis

Volumn 31, Issue 4, 2001, Pages 173-184

  Schöier, Johan ^a   Öllinger, Karin ^a   Kvarnström, Maria ^a   Söderlund, Gustaf ^a   Kihlström, Erik ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Apoptosis; Chlamydia trachomatis; McCoy cells; Reactive oxygen species

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BACTERIAL PROTEIN; CASPASE 3; CHLORAMPHENICOL; PROPIDIUM IODIDE; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL MATURATION; CHLAMYDIA TRACHOMATIS; CHLAMYDIASIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; NICK END LABELING; NUCLEOSOME; OXIDATION REDUCTION REACTION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

BACTERIA (MICROORGANISMS); CHLAMYDIA TRACHOMATIS;

EID: 0034783571     PISSN: 08824010     EISSN: None     Source Type: Journal    
DOI: 10.1006/mpat.2001.0460     Document Type: Article

References (57)

1. Chlamydia trachomatis interrupts an exocytic pathway to acquire endogenously synthesized sphingomyelin in transit from the Golgi apparatus to the plasma membrane
2. Sphingolipids and glycoproteins are differentially trafficked to the Chlamydia trachomatis inclusion
3. Selective translocation of annexins during intracellular redistribution of Chlamydia trachomatis in HeLa and McCoy cells
4. Interaction of Chlamydiae and host cells in vitro
5. The interaction of Chlamydia trachomatis with host cells: Ultrastructural studies of the mechanism of release of a biovar II strain from HeLa 229 cells
6. To die or not to die. An overview of apoptosis and its role in disease
7. Apoptosis: Pathophysiology of programmed cell death
8. Control of apoptosis by the cellular ATP level
9. Apoptosis in the pathogenesis and treatment of disease
10. Caspases: The proteases of the apoptotic pathway
11. Emerging roles of caspase-3 in apoptosis
12. Free radicals and reactive oxygen species in programmed cell death
13. Reactive oxygen species and antioxidant vitamins: Mechanism of action
14. Caspases: Intracellular signaling by proteolysis
15. Viruses and apoptosis
16. Apoptosis - Role in infection and inflammation
17. Programmed cell death of Mycobacterium avium serovar 4-infected human macrophages prevents the mycobacteria from spreading and induces mycobacterial growth inhibition by freshly added, uninfected macrophages
18. Apoptosis as a proinflammatory event: What can we learn from bacteria-induced cell death?
19. Inhibition of tumor necrosis factor and interferon triggered responses by DNA viruses
20. Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35
21. Epstein-Bart virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death
22. Abrogation of p53-induced apoptosis by the hepatitis B virus X gene
23. Distinct domains of M-T2, the myxoma virus tumor necrosis factor (TNF) receptor homolog, mediate extracellular TNF binding and intracellular apoptosis inhibition
24. Effect of Chlamydia trachomatis infection and subsequent tumor necrosis factor alpha secretion on apoptosis in the murine genital tract
25. Induction of apoptosis by Chlamydia psittaci and Chlamydia trachomatis infection in tissue culture cells
26. Apoptosis of epithelial cells and macrophages due to infection with the obligate intracellular pathogen Chlanzydia psittaci
27. Chlamydia pneumoniae inhibits apoptosis in human peripheral blood mononuclear cells through induction of IL-10
28. Inhibition of apoptosis in chlamydia-infected cells: Blockade of mitochondrial cytochrome c release and caspase activation
29. Measurement of cell death
30. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
31. Reactive oxygen species in living systems: Source, biochemistry, and role in human disease
32. Effects of ascorbic acid on Chlamydia trachomatis infection and on erythromycin treatment in primary cultures of human amniofic cells
33. Induction of apoptosis in MDA-231 cells by protein synthesis inhibitors is suppressed by multiple agents
34. Reevaluation of the role of de novo protein synthesis in rat thymocyte apoptosis
35. Oxidative stress, growth factor starvation and Fas activation may all cause apoptosis through lysosomal leak
36. Critical aspects in the analysis of apoptosis and necrosis
37. Secretion of proinflammatory cytokines by epithelial cells in response to chlamydia infection suggests a central role for epithelial cells in chlamydial pathogenesis
38. Tumor necrosis factor-α response to infection with Chlamydia trachomatis in human fallopian tube organ culture
39. Oxidative stress as a mediator of apoptosis
40. Regulation of reactive oxygen species-induced apoptosis and necrosis by caspase-3-like proteases
41. Ascorbate and α-tocopherol prevent apoptosis induced by serum removal independent of Bcl-2
42. Essential fatty acids, lipid peroxidation and apoptosis
43. Generation of reactive oxygen species and formation of membrane lipid peroxides in cells infected with Chlamydia trachomatis
44. Activation of caspase-3 during Legionella pneumophila-induced apoptosis
45. The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1
46. The interleukin 1β-converting enzyme, caspase 1, is activated during Shigella flexneri-induced apoptosis in human monocyte-derived macrophages
47. Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB
48. Apoptosis: Checkpoint at the mitochondrial frontier
49. A combinatorial approach defines specificities of members of the caspase family and granzyme B
50. Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock
51. Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN-γ production
52. Chlamydia trachomatis infection of human mesothelial cells alters proinflammatory, procoagulant and fibrolytic responses
53. Chlamydia trachomatis infection of epithelial cells induces the activation of caspase-1 and release of mature IL-18
54. Infection of human monocyte-derived macrophages with Chlamydia trachomatis induces apoptosis of T cells: A potential mechanism for persistent infection
55. Repeated and persistent infection with Chlamydia and the development of chronic inflammation and disease
56. Vitamin C and E prevent lipopolysaccharide-induced apoptosis in human endothelial cells by modulation of Bcl-2 and Bax
57. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation