Embryonic stem cells as an in vitro model for mutagenicity, cytotoxicity and embryotoxicity studies: Present state and future prospects

Toxicology in Vitro

Volumn 15, Issue 6, 2001, Pages 741-753

  Rohwedel, J ^a   Guan, K ^b   Hegert, C ^a   Wobus, A M ^b  

^a UNIVERSITY OF LÜBECK   (Germany)

^b LEIBNIZ INSTITUTE OF PLANT GENETICS AND CROP PLANT RESEARCH IPK   (Germany)

Author keywords

Cytotoxicity; Differentiation; Embryonic stem cells; Embryotoxicity; Gene expression patterns; Mouse; Mutagenicity

Indexed keywords

ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CELL RENEWAL; CELL TYPE; CYTOTOXICITY; DRUG METABOLISM; EMBRYO CULTURE; EMBRYO DEVELOPMENT; EMBRYONAL CARCINOMA; EMBRYOTOXICITY; ENVIRONMENTAL FACTOR; GENE EXPRESSION; GERM CELL; IN VITRO STUDY; MUTAGENICITY; NONHUMAN; STEM CELL; TOXICITY TESTING; XENOBIOTIC METABOLISM;

VERTEBRATA;

EID: 0034767399     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0887-2333(01)00074-1     Document Type: Short Survey

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