Permanent embryonic germ cell lines of BALB/cJ mice - An in vitro alternative for in vivo germ cell mutagenicity tests

Toxicology in Vitro

Volumn 15, Issue 4-5, 2001, Pages 447-453

  Klemm, M ^a   Genschow, E ^a   Pohl, I ^a   Barrabas, C ^a   Liebsch, M ^a   Spielmann, H ^a  

^a FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

Author keywords

Cytotoxicity; Discriminant analysis; EG cell lines; Genotoxic potential; Germ cell mutagenicity; Prediction model

Indexed keywords

ASCORBIC ACID; ETHYLNITROSOUREA; HYDROXYUREA; MESYLIC ACID METHYL ESTER; METHYLNITROSOUREA; MITOMYCIN; PENICILLIN G; SACCHARIN; TOXIC SUBSTANCE;

ACCURACY; ANIMAL CELL; BIOSTATISTICS; CELL STRAIN 3T3; CONFERENCE PAPER; CONTROLLED STUDY; CYTOTOXICITY; DISCRIMINANT ANALYSIS; FEMALE; FIBROBLAST; GENOTOXICITY; GERM CELL; MALE; METAPHASE; MOUSE; MUTAGEN TESTING; NITROBLUE TETRAZOLIUM TEST; NONHUMAN; REPRODUCTIVE TOXICITY; SISTER CHROMATID EXCHANGE;

3T3 CELLS; ANIMAL TESTING ALTERNATIVES; ANIMALS; CELL SURVIVAL; DISCRIMINANT ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FIBROBLASTS; GERM CELLS; MALE; MICE; MICE, INBRED BALB C; MODELS, STATISTICAL; MUTAGENICITY TESTS; MUTAGENS; PREDICTIVE VALUE OF TESTS; SEX DETERMINATION (ANALYSIS); SISTER CHROMATID EXCHANGE; TETRAZOLIUM SALTS;

EID: 0034832748     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0887-2333(01)00050-9     Document Type: Conference Paper

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