Essential role of HIV type 1-infected and cyclooxygenase 2-activated macrophages and T cells in HIV type 1 myocarditis

AIDS Research and Human Retroviruses

Volumn 17, Issue 15, 2001, Pages 1423-1433

  Liu, Q Nancy ^a   Reddy, Srinu ^a,b   Sayre, James W ^c   Pop, Viorela ^a   Graves, Michael C ^d   Fiala, Milan ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b Medical Pharmacology ^*  (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD8 ANTIGEN; CYCLOOXYGENASE 2; FIBRINOGEN; GLYCOPROTEIN GP 120; NEF PROTEIN; NITRIC OXIDE SYNTHASE; PROTEIN; PROTEIN ZO1; UNCLASSIFIED DRUG;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; AIDS RELATED COMPLEX; ANTIGEN RETRIEVAL; ARTICLE; BLOOD VESSEL PERMEABILITY; CARDIOMYOPATHY; CELL INFILTRATION; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY BLOOD VESSEL; DISEASE COURSE; HEART DILATATION; HEART MUSCLE CELL; HISTOPATHOLOGY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; MACROPHAGE; MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; TIGHT JUNCTION; VIRUS MYOCARDITIS;

BRAIN; CORONARY VESSELS; CYCLOOXYGENASE 2; HIV INFECTIONS; HIV-1; HUMANS; ISOENZYMES; KIDNEY; LEUKOCYTES; LIVER; LYMPHOCYTE ACTIVATION; MACROPHAGE ACTIVATION; MACROPHAGES; MEMBRANE PROTEINS; MYOCARDITIS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; T-LYMPHOCYTES; VENTRICULAR DYSFUNCTION, LEFT;

EID: 0034761143     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/088922201753197097     Document Type: Article

References (50)

1. Incidence of dilated cardiomyopathy and detection of HIV in myocardial cells of HIV-positive patients
2. Infection of the human heart by the human immunodeficiency virus
3. Identification of human immunodeficiency virus-1 RNA and DNA in the heart of a child with cardiovascular abnormalities and congenital acquired immune deficiency syndrome
4. Identification of human immunodeficiency virus in the heart of a patient with acquired immunodeficiency syndrome
5. Cardiac involvement in the acquired immunodeficiency syndrome: A multicenter clinical-pathological study
6. Cardiomyopathy and other symptomatic heart diseases associated with HIV infection
7. The detection of viral genomes by polymerase chain reaction in the myocardium of pediatric patients with advanced HIV disease
8. HIV-associated myocarditis. Pathology and immunopathology
9. Myocarditis. A histopathologic definition and classification
10. Pancreatic expression of interferon-gamma protects mice from lethal coxsackievirus B3 infection and subsequent myocarditis
11. Enteroviral protease 2A cleaves dystrophin: Evidence of cytoskeletal disruption in an acquired cardiomyopathy
12. Chlamydia infections and heart disease linked through antigenic mimicry
13. Human immunodeficiency virus type 1 infection of the nervous system: Pathogenetic mechanisms
14. Antigen retrieval immunohistochemistry under the influence of pH using monoclonal antibodies
15. Infection of human fetal cardiac myocytes by a human immunodeficiency virus-1-derived vector
16. The neuropathogenesis of the AIDS dementia complex
17. Macrophages infiltrate brain and express COX-2 and iNOS in Alzheimer's disease and AIDS
18. CD40-CD40 ligand
19. The emerging role of CD40 ligand in HIV infection
20. A Trojan Horse mechanism for the spread of visna virus in monocytes
21. HIV-1 penetrates through coronary artery endothelial cells by transcytosis
22. Identification of human immunodeficiency virus-1 RNA and DNA in the heart of a child with cardiovascular abnormalities and congenital acquired immune deficiency syndrome
23. In vivo and in vitro infection of the astrocyte by HIV-1
24. Astrocytes: HIV cellular reservoirs and important participants in neuropathogenesis
25. Cardiomyopathy in AIDS: A pathophysiological perspective
26. Cocaine enhances endothelial adhesion molecules and leukocyte migration
27. Chemokines and soluble adhesion molecules in renal transplant recipients with cytomegalovirus infection
28. Cytomegalovirus-encoded beta chemokine promotes monocyte-associated viremia in the host
29. Viral damage or "molecular mimicry"-placing the blame in myocarditis
30. 2biosynthesis in macrophages
31. Prostaglandin endoperoxide synthase: Regulation of enzyme expression
32. Prostaglandin synthase 2
33. Function and regulation of prostaglandin synthase 2
34. Induction of cyclooxygenase-2 and activation of nuclear factor-kappaB in myocardium of patients with congestive heart failure
35. Nitric oxide as a secretory product of mammalian cells
36. Cloning and characterization of inducible nitric oxide synthase from mouse macrophages
37. Nitric oxide inhibits viral replication in murine myocarditis
38. The role of inducible nitric oxide synthase in the host response to coxsackievirus myocarditis
39. Nitric oxide and murine coxsackievirus B3 myocarditis: Aggravation of myocarditis by inhibition of nitric oxide synthase
40. An inhibitor of inducible nitric oxide synthase ameliorates experimental autoimmune myocarditis in Lewis rats
41. Nitric oxide synthase in experimental autoimmune myocarditis dysfunction
42. Pimobendan inhibits the production of proinflammatory cytokines and gene expression of inducible nitric oxide synthase in a murine model of viral myocarditis
43. Nitric oxide contributes to the progression of myocardial damage in experimental autoimmune myocarditis in rats
44. Function and regulation of prostaglandin synthase-2
45. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
46. Human immunodeficiency virus-infected macrophages produce soluble factors that cause histological and neurochemical alterations in cultured human brains
47. Cellular localization of tumor necrosis factor mRNA in neurological tissue from HIV-infected patients by combined reverse transcriptase/polymerase chain reaction in situ hybridization and immunohistochemistry
48. Seminars in medicine of the Beth Israel Hospital, Boston. Dementia associated with the acquired immunodeficiency syndrome
49. Study of receptor-mediated neurotoxins released by HIV-1 infected mononuclear phagocytes found in human brain
50. HIV-1 infected mononuclear phagocyte secretory products affect neuronal physiology leading to cellular demise: Relevance for HIV-1-associated dementia