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Volumn 16, Issue 10, 1996, Pages 3139-3153

Study of receptor-mediated neurotoxins released by HIV-1-infected mononuclear phagocytes found in human brain

Author keywords

AIDS; brain; dementia; gp120; HIV 1; macrophage; microglia; neurotoxin; NMDA; quinolinic acid

Indexed keywords

EXCITOTOXIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROTOXIN; QUINOLINIC ACID;

EID: 0030002044     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-10-03139.1996     Document Type: Article
Times cited : (142)

References (58)
  • 1
    • 84914639435 scopus 로고
    • Estimation of nuclear population from microtome sections
    • Abercrombie M (1946) Estimation of nuclear population from microtome sections. Anat Rec 94:239-247.
    • (1946) Anat Rec , vol.94 , pp. 239-247
    • Abercrombie, M.1
  • 2
    • 0027225504 scopus 로고
    • Quantitation of human immunodeficiency virus, immune activation factors, and quinolinic acid in AIDS brain
    • Achim CL, Heyes MP, Wiley CA (1993) Quantitation of human immunodeficiency virus, immune activation factors, and quinolinic acid in AIDS brain. J Clin Invest 91:2769-2775.
    • (1993) J Clin Invest , vol.91 , pp. 2769-2775
    • Achim, C.L.1    Heyes, M.P.2    Wiley, C.A.3
  • 3
    • 0009644628 scopus 로고
    • Some quantitative uses of drug antagonists
    • Arunlakshana O, Schild HO (1959) Some quantitative uses of drug antagonists. Br J Pharmacol 14:48-57.
    • (1959) Br J Pharmacol , vol.14 , pp. 48-57
    • Arunlakshana, O.1    Schild, H.O.2
  • 4
    • 0024389823 scopus 로고
    • Acylpolyamines mimic the action of Joro spider toxin (JSTX) on crustacean muscle glutamate receptors
    • Asami T, Kagechika H, Hashimoto Y, Shudo K, Miwa A, Kawai N, Nakajima T (1989) Acylpolyamines mimic the action of Joro spider toxin (JSTX) on crustacean muscle glutamate receptors. Biomed Res 10:185-189.
    • (1989) Biomed Res , vol.10 , pp. 185-189
    • Asami, T.1    Kagechika, H.2    Hashimoto, Y.3    Shudo, K.4    Miwa, A.5    Kawai, N.6    Nakajima, T.7
  • 5
    • 0026347825 scopus 로고
    • Aminooxyacetic acid results in excitotoxin lesions by a novel indirect mechanism
    • Beal MF, Swartz KJ, Hyman BT, Storey E, Finn SF (1991) Aminooxyacetic acid results in excitotoxin lesions by a novel indirect mechanism. J Neurochem 57:1068-1073.
    • (1991) J Neurochem , vol.57 , pp. 1068-1073
    • Beal, M.F.1    Swartz, K.J.2    Hyman, B.T.3    Storey, E.4    Finn, S.F.5
  • 6
    • 0026702955 scopus 로고
    • Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death
    • Boje KM, Arora PK (1992) Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death. Brain Res 587:250-256.
    • (1992) Brain Res , vol.587 , pp. 250-256
    • Boje, K.M.1    Arora, P.K.2
  • 7
    • 0000854861 scopus 로고
    • Growth of a rat neuroblastoma cell line in serum-free supplemented medium
    • Bottenstein JE, Sato GH (1979) Growth of a rat neuroblastoma cell line in serum-free supplemented medium. Proc Natl Acad Sci USA 76:514-517.
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 514-517
    • Bottenstein, J.E.1    Sato, G.H.2
  • 9
    • 0024498421 scopus 로고
    • Human immunodeficiency virus (HIV)-induced disease of the central nervous system: Pathology and implications for pathogenesis
    • Budka H (1989) Human immunodeficiency virus (HIV)-induced disease of the central nervous system: pathology and implications for pathogenesis. Acta Neuropathol 77:225-236.
    • (1989) Acta Neuropathol , vol.77 , pp. 225-236
    • Budka, H.1
  • 10
    • 0023642584 scopus 로고
    • Production of superoxide anion by a CNS macrophage, the microglia
    • Colton CA, Gilbert DL (1987) Production of superoxide anion by a CNS macrophage, the microglia. FEBS Lett 223:284-288.
    • (1987) FEBS Lett , vol.223 , pp. 284-288
    • Colton, C.A.1    Gilbert, D.L.2
  • 11
    • 0028335308 scopus 로고
    • Human monocytes/macrophages: NO or no NO?
    • Denis M (1994) Human monocytes/macrophages: NO or no NO? J Leukoc Biol 55:682-684.
    • (1994) J Leukoc Biol , vol.55 , pp. 682-684
    • Denis, M.1
  • 12
    • 0025278342 scopus 로고
    • HIV-1 coat protein neurotoxicity prevented by calcium channel antagonists
    • Dreyer EB, Kaiser PK, Offermann JT, Lipton SA (1990) HIV-1 coat protein neurotoxicity prevented by calcium channel antagonists. Science 248:364-367.
    • (1990) Science , vol.248 , pp. 364-367
    • Dreyer, E.B.1    Kaiser, P.K.2    Offermann, J.T.3    Lipton, S.A.4
  • 13
    • 0027325328 scopus 로고
    • HIV-1 infection of the nervous system: Pathogenetic mechanisms
    • Epstein LG, Gendelman HE (1993) HIV-1 infection of the nervous system: pathogenetic mechanisms. Ann Neurol 33:429-436.
    • (1993) Ann Neurol , vol.33 , pp. 429-436
    • Epstein, L.G.1    Gendelman, H.E.2
  • 14
    • 0022819679 scopus 로고
    • AIDS: An overview of CNS complications and neuropsychological sequelae
    • Faulstich ME (1986) AIDS: an overview of CNS complications and neuropsychological sequelae. Int J Neurosci 30:249-254.
    • (1986) Int J Neurosci , vol.30 , pp. 249-254
    • Faulstich, M.E.1
  • 15
    • 0014073089 scopus 로고
    • Two methods for selective silver impregnation of degenerating axons and their synaptic endings in the central nervous system
    • Fink RP, Heimer L (1967) Two methods for selective silver impregnation of degenerating axons and their synaptic endings in the central nervous system. Brain Res 4:369-374.
    • (1967) Brain Res , vol.4 , pp. 369-374
    • Fink, R.P.1    Heimer, L.2
  • 17
    • 0023227681 scopus 로고
    • Neurologic manifestations of infection with human immunodeficiency virus
    • Gabuzda DH, Hirsch MS (1987) Neurologic manifestations of infection with human immunodeficiency virus. Ann Intern Med 107:383-391.
    • (1987) Ann Intern Med , vol.107 , pp. 383-391
    • Gabuzda, D.H.1    Hirsch, M.S.2
  • 19
    • 0027155807 scopus 로고
    • Diffuse microgliosis associated with cerebral atrophy in the acquired immunodeficiency syndrome
    • Gelman BB (1993) Diffuse microgliosis associated with cerebral atrophy in the acquired immunodeficiency syndrome. Ann Neurol 34:65-70.
    • (1993) Ann Neurol , vol.34 , pp. 65-70
    • Gelman, B.B.1
  • 21
    • 0026440742 scopus 로고
    • Cytokines and arachidonic metabolites produced during HIV-infected macrophage-astroglia interactions: Implications for the neuropathogenesis of HIV disease
    • Genis P, Jett M, Bernton EW, Boyle T, Gelbard HA, Dzenko K, Keane RW, Resnick L, Mizrachi Y, Volsky DJ (1992) Cytokines and arachidonic metabolites produced during HIV-infected macrophage-astroglia interactions: implications for the neuropathogenesis of HIV disease. J Exp Med 176:1703-1718.
    • (1992) J Exp Med , vol.176 , pp. 1703-1718
    • Genis, P.1    Jett, M.2    Bernton, E.W.3    Boyle, T.4    Gelbard, H.A.5    Dzenko, K.6    Keane, R.W.7    Resnick, L.8    Mizrachi, Y.9    Volsky, D.J.10
  • 22
    • 3242709147 scopus 로고
    • Brain inflammatory cells, neurotoxins, and acquired immunodeficiency syndrome
    • Giulian D (1992a) Brain inflammatory cells, neurotoxins, and acquired immunodeficiency syndrome. Fidia Res Found Symp Ser 9:229-234.
    • (1992) Fidia Res Found Symp Ser , vol.9 , pp. 229-234
    • Giulian, D.1
  • 23
    • 0001352432 scopus 로고
    • Microglia and diseases of the nervous system
    • Giulian D (1992b) Microglia and diseases of the nervous system. Curr Neurol 12:23-54.
    • (1992) Curr Neurol , vol.12 , pp. 23-54
    • Giulian, D.1
  • 24
    • 0000249986 scopus 로고
    • Microglia and neuron dysfunction
    • Kettenmann H, Ransom B, eds. Oxford: Oxford UP
    • Giulian D (1995) Microglia and neuron dysfunction. In: Neuroglia (Kettenmann H, Ransom B, eds), pp 671-684. Oxford: Oxford UP.
    • (1995) Neuroglia , pp. 671-684
    • Giulian, D.1
  • 25
    • 0022922108 scopus 로고
    • Characterization of ameboid microglia isolated from developing mammalian brain
    • Giulian D, Baker TJ (1986) Characterization of ameboid microglia isolated from developing mammalian brain. J Neurosci 6:2163-2178.
    • (1986) J Neurosci , vol.6 , pp. 2163-2178
    • Giulian, D.1    Baker, T.J.2
  • 26
    • 0025609978 scopus 로고
    • HIV-1-infected mononuclear phagocytes release neurotoxins
    • Giulian D, Noonan C, Vaca K (1990) HIV-1-infected mononuclear phagocytes release neurotoxins. Science 250:1593-1595.
    • (1990) Science , vol.250 , pp. 1593-1595
    • Giulian, D.1    Noonan, C.2    Vaca, K.3
  • 27
    • 0027407936 scopus 로고
    • The envelope glycoprotein of HIV-1 stimulates monocyte release of neurotoxins
    • Giulian D, Wendt E, Vaca K, Noonan C (1993a) The envelope glycoprotein of HIV-1 stimulates monocyte release of neurotoxins. Proc Natl Acad Sci USA 90:2769-2773.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 2769-2773
    • Giulian, D.1    Wendt, E.2    Vaca, K.3    Noonan, C.4
  • 28
    • 0027463358 scopus 로고
    • Brain glia release factors with opposing actions upon neuronal survival
    • Giulian D, Vaca K, Corpuz M (1993b) Brain glia release factors with opposing actions upon neuronal survival. J Neurosci 13:29-37.
    • (1993) J Neurosci , vol.13 , pp. 29-37
    • Giulian, D.1    Vaca, K.2    Corpuz, M.3
  • 29
    • 0028105846 scopus 로고
    • Phagocytic microglia release cytokines and cytotoxins that regulate survival of astrocytes and neurons in culture
    • Giulian D, Leara B, Keenan C, Li J (1994) Phagocytic microglia release cytokines and cytotoxins that regulate survival of astrocytes and neurons in culture. Neurochem Int 25:227-233.
    • (1994) Neurochem Int , vol.25 , pp. 227-233
    • Giulian, D.1    Leara, B.2    Keenan, C.3    Li, J.4
  • 31
    • 0028881820 scopus 로고
    • Cell surface morphology identifies microglia to be a distinct class of mononuclear phagocytes
    • Giulian D, Li J, Bartel S, Broker J, Li X (1995b) Cell surface morphology identifies microglia to be a distinct class of mononuclear phagocytes. J Neurosci 15:7712-7726.
    • (1995) J Neurosci , vol.15 , pp. 7712-7726
    • Giulian, D.1    Li, J.2    Bartel, S.3    Broker, J.4    Li, X.5
  • 33
    • 0025330797 scopus 로고
    • Increased cerebrospinal fluid quinolinic acid, kynurenic acid, and L-kynurenine in acute septicemia
    • Heyes MP, Lackner A (1990) Increased cerebrospinal fluid quinolinic acid, kynurenic acid, and L-kynurenine in acute septicemia. J Neurochem 55:338-341.
    • (1990) J Neurochem , vol.55 , pp. 338-341
    • Heyes, M.P.1    Lackner, A.2
  • 34
    • 0023779515 scopus 로고
    • Quantification of quinolinic acid in rat brain, whole blood, and plasma by gas chromatography and negative chemical ionization mass spectrometry: Effects of systemic L-tryptophan administration on brain and blood quinolinic acid concentrations
    • Heyes MP, Markey SP (1988) Quantification of quinolinic acid in rat brain, whole blood, and plasma by gas chromatography and negative chemical ionization mass spectrometry: effects of systemic L-tryptophan administration on brain and blood quinolinic acid concentrations. Anal Biochem 174:349-359.
    • (1988) Anal Biochem , vol.174 , pp. 349-359
    • Heyes, M.P.1    Markey, S.P.2
  • 35
    • 0024358634 scopus 로고
    • Cerebrospinal fluid quinolinic acid concentrations are increased in acquired immune deficiency syndrome
    • Heyes MP, Rubinow D, Lane C, Markey SP (1989) Cerebrospinal fluid quinolinic acid concentrations are increased in acquired immune deficiency syndrome. Ann Neurol 26:275-277.
    • (1989) Ann Neurol , vol.26 , pp. 275-277
    • Heyes, M.P.1    Rubinow, D.2    Lane, C.3    Markey, S.P.4
  • 38
    • 0025272486 scopus 로고
    • Loss of neurons in the frontal cortex in AIDS brains
    • Berl
    • Ketzler S, Weis S, Haug H, Budka H (1990) Loss of neurons in the frontal cortex in AIDS brains. Acta Neuropathol (Berl) 80:92-94.
    • (1990) Acta Neuropathol , vol.80 , pp. 92-94
    • Ketzler, S.1    Weis, S.2    Haug, H.3    Budka, H.4
  • 39
    • 0024295774 scopus 로고
    • Neuroregulatory and neuropathological actions of the ether-phospholipid platelet-activating factor
    • Kornecki E, Ehrlich YH (1988) Neuroregulatory and neuropathological actions of the ether-phospholipid platelet-activating factor. Science 240:1792-1794.
    • (1988) Science , vol.240 , pp. 1792-1794
    • Kornecki, E.1    Ehrlich, Y.H.2
  • 40
    • 0025121386 scopus 로고
    • Isolation, structure elucidation, and synthesis of novel hydroxylamine-containing polyamines from the venom of the Agelenopsis aperta spider
    • Jasys VJ, Kelbaugh PR, Nason DM, Phillips D, Rosnack KJ, Saccomano NA, Stroh JG, Volkmann RA (1990) Isolation, structure elucidation, and synthesis of novel hydroxylamine-containing polyamines from the venom of the Agelenopsis aperta spider. J Am Chem Soc 112:6696-6704.
    • (1990) J Am Chem Soc , vol.112 , pp. 6696-6704
    • Jasys, V.J.1    Kelbaugh, P.R.2    Nason, D.M.3    Phillips, D.4    Rosnack, K.J.5    Saccomano, N.A.6    Stroh, J.G.7    Volkmann, R.A.8
  • 41
    • 0026758027 scopus 로고
    • Requirement for macrophages in neuronal injury induced by HIV envelope protein gp120
    • Lipton SA (1992a) Requirement for macrophages in neuronal injury induced by HIV envelope protein gp120. NeuroReport 3:913-915.
    • (1992) NeuroReport , vol.3 , pp. 913-915
    • Lipton, S.A.1
  • 42
    • 0026569410 scopus 로고
    • Models of neuronal injury in AIDS: Another role for the NMDA receptor?
    • Lipton SA (1992b) Models of neuronal injury in AIDS: another role for the NMDA receptor? Trends Neurosci 15:75-79.
    • (1992) Trends Neurosci , vol.15 , pp. 75-79
    • Lipton, S.A.1
  • 46
    • 0022518134 scopus 로고
    • The AIDS dementia complex. 1. Clinical features
    • Navia BA, Jordan BD, Price RW (1986b) The AIDS dementia complex. 1. Clinical features. Ann Neurol 19:517-524.
    • (1986) Ann Neurol , vol.19 , pp. 517-524
    • Navia, B.A.1    Jordan, B.D.2    Price, R.W.3
  • 47
    • 0026450788 scopus 로고
    • Blood-brain barrier abnormalities in the acquired immunodeficiency syndrome: Immunohistochemical localization of serum proteins in postmortem brain
    • Petito CK, Cash KS (1992) Blood-brain barrier abnormalities in the acquired immunodeficiency syndrome: immunohistochemical localization of serum proteins in postmortem brain. Ann Neurol 32:658-666.
    • (1992) Ann Neurol , vol.32 , pp. 658-666
    • Petito, C.K.1    Cash, K.S.2
  • 48
    • 0028157362 scopus 로고
    • Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody
    • Petralia RS, Yokotani N, Wenthold RJ (1994) Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody. J Neurosci 14:667-696.
    • (1994) J Neurosci , vol.14 , pp. 667-696
    • Petralia, R.S.1    Yokotani, N.2    Wenthold, R.J.3
  • 49
    • 0025963498 scopus 로고
    • HIV-1 infected macrophages produce soluble factors that cause histological and neurochemical alterations in cultured human brains
    • Pulliam L, Herndier BG, Tang NM, McGrath MS (1991) HIV-1 infected macrophages produce soluble factors that cause histological and neurochemical alterations in cultured human brains. J Clin Invest 87:503-512.
    • (1991) J Clin Invest , vol.87 , pp. 503-512
    • Pulliam, L.1    Herndier, B.G.2    Tang, N.M.3    McGrath, M.S.4
  • 51
    • 0027408778 scopus 로고
    • 4-Chloro-3-hydroxyanthranilate, 6-chlorotryptophan, and norharmane attenuate quinolinic acid formation by interferon gamma-stimulated monocytes (THP-1 cells)
    • Saito K, Chen CY, Masana M, Crowley JS, Markey SP, Heyes MP (1993) 4-Chloro-3-hydroxyanthranilate, 6-chlorotryptophan, and norharmane attenuate quinolinic acid formation by interferon gamma-stimulated monocytes (THP-1 cells). Biochem J 291:11-14.
    • (1993) Biochem J , vol.291 , pp. 11-14
    • Saito, K.1    Chen, C.Y.2    Masana, M.3    Crowley, J.S.4    Markey, S.P.5    Heyes, M.P.6
  • 52
    • 0020702374 scopus 로고
    • Quinolinic acid: An endogenous metabolite that produces axon-sparing lesions in rat brain
    • Schwarcz R, Whetsell WO, Mangano RM (1983) Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain. Science 219:316-318.
    • (1983) Science , vol.219 , pp. 316-318
    • Schwarcz, R.1    Whetsell, W.O.2    Mangano, R.M.3
  • 54
    • 0025935041 scopus 로고
    • Cytotoxic effect of brain macrophages on developing neurons
    • Thery C, Chamak B, Mallat M (1991) Cytotoxic effect of brain macrophages on developing neurons. Eur J Neurosci 3:1155-1164.
    • (1991) Eur J Neurosci , vol.3 , pp. 1155-1164
    • Thery, C.1    Chamak, B.2    Mallat, M.3
  • 55
    • 0025779659 scopus 로고
    • 4-Halo-3-hydroxyanthroanilic acids: Potent competitive inhibitors of 2-hydroxyanthranilic acid oxygenase in vitro
    • Walsh J, Todd WP, Carpenter BK, Schwarcz R (1991) 4-Halo-3-hydroxyanthroanilic acids: potent competitive inhibitors of 2-hydroxyanthranilic acid oxygenase in vitro. Biochem Pharmacol 42:985-990.
    • (1991) Biochem Pharmacol , vol.42 , pp. 985-990
    • Walsh, J.1    Todd, W.P.2    Carpenter, B.K.3    Schwarcz, R.4
  • 56
    • 0024499063 scopus 로고
    • Prolonged exposure to submicromolar concentrations of quinolinic acid causes excitotoxic damage in organotypic cultures of rat corticostriatal system
    • Whetsell WO, Schwarcz R (1989) Prolonged exposure to submicromolar concentrations of quinolinic acid causes excitotoxic damage in organotypic cultures of rat corticostriatal system. Neurosci Lett 97:271-275.
    • (1989) Neurosci Lett , vol.97 , pp. 271-275
    • Whetsell, W.O.1    Schwarcz, R.2
  • 58
    • 0025063670 scopus 로고
    • Characterization of polyamines having agonist, antagonist, an inverse agonist effects at the polyamine recognition site of the NMDA receptor
    • Williams K, Dawson VL, Romano C, Dichter MA, Molinoff PB (1990) Characterization of polyamines having agonist, antagonist, an inverse agonist effects at the polyamine recognition site of the NMDA receptor. Neuron 5:199-208.
    • (1990) Neuron , vol.5 , pp. 199-208
    • Williams, K.1    Dawson, V.L.2    Romano, C.3    Dichter, M.A.4    Molinoff, P.B.5


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