Assembly of the human signal recognition particle (SRP): Overlap of regions required for binding of protein SRP54 and assembly control

RNA

Volumn 7, Issue 10, 2001, Pages 1389-1396

  Yin, Jiaming ^a   Yang, Ching Hui ^a   Zwieb, Christian ^a  

^a UNIVERSITY OF TEXAS HEALTH CENTER   (United States)

Author keywords

Assembly; RNA protein interactions; RNP; Site directed mutagenesis

Indexed keywords

PROTEIN; PROTEIN SRP 54; SIGNAL RECOGNITION PARTICLE; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; HUMAN; METHANOCOCCUS JANNASCHII; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN RNA BINDING; RNA CONFORMATION; SITE DIRECTED MUTAGENESIS;

BASE SEQUENCE; BINDING SITES; CHIMERA; DNA PRIMERS; HUMANS; METHANOCOCCUS; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID CONFORMATION; PLASMIDS; RNA, BACTERIAL; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL RECOGNITION PARTICLE;

METHANOCALDOCOCCUS JANNASCHII; METHANOCOCCUS;

EID: 0034757628     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Structure of the S15, S6, S18-rRNA complex: Assembly of the 30S ribosome central domain
2. Crystal structure of the ribonucleoprotein core of the signal recognition particle
3. Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle
4. Assembly of archaeal signal recognition particle from recombinant components
5. New insights into signal recognition and elongation arrest activities of the signal recognition particle
6. Crystal structure of the conserved subdomain of human protein SRP54M at 2,1 Å resolution: Evidence for the mechanism of signal peptide binding
7. Role of SRP19 in assembly of the Archaeoglobus fulgidus signal recognition particle
8. SRPDB (signal recognition particle database)
9. Protein SRP54 of human signal recognition particle: Cloning, expression, and comparative analysis of functional sites
10. Binding site of the M-domain of human protein SRP 54 determined by systematic site directed mutagenesis of signal recognition particle RNA
11. Determinants of a protein-induced RNA switch in the large domain of signal recognition particle identified by systematic site-directed mutagenesis
12. The signal sequence of nascent preprolactin interacts with the 54K polypeptide of the signal recognition particle
13. SRP-RNA sequence alignment and secondary structure
14. Isolation and characterization of a cDNA clone encoding the 19 kDa protein of signal recognition particle (SRP): Expression and binding to 7SL RNA
15. Signal recognition particle (SRP), a ubiquitous initiator of protein translocation
16. The methionine-rich domain of the 54 kDa subunit of signal recognition particle is sufficient for the interaction with signal sequences
17. A general method of site-specific mutagenesis using a modification of the Thermus aquaticus polymerase
18. Homology of 54K protein of signal-recognition particle, docking protein and two E. coli proteins with putative GTP-binding domains
19. The 54-kD protein of signal recognition particle contains a methionine-rich RNA binding domain
20. Visualizing induced fit in early assembly of the human signal recognition particle
21. Cooperative assembly of signal recognition particle RNA with protein SRP19
22. Disassembly and reconstitution of the signal recognition particle
23. The 2 Å structure of helix 6 of the human signal recognition particle RNA
24. Swapping of functional domains using a chimeric monster deletion mutagenesis strategy
25. Interaction of protein SRP19 with signal recognition particle RNA lacking individual RNA helices
26. Recognition of a tetranucleotide loop of signal recognition particle RNA by protein SRP19