메뉴 건너뛰기




Volumn 7, Issue 11, 2001, Pages 512-516

Rethinking genetic strategies to study complex diseases

Author keywords

[No Author keywords available]

Indexed keywords

BIOSTATISTICS; GENE MUTATION; GENETIC ANALYSIS; GENETIC DISORDER; HUMAN; HYPOTHESIS; PATHOPHYSIOLOGY; REVIEW; SIGNAL NOISE RATIO; SIGNAL PROCESSING; STANDARD; SYNDROME DELINEATION; TECHNOLOGY;

EID: 0034753547     PISSN: 14714914     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4914(01)02163-3     Document Type: Review
Times cited : (13)

References (43)
  • 5
    • 0024424270 scopus 로고
    • Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
    • (1989) Science , vol.245 , pp. 1066-1073
    • Riordan, J.R.1
  • 6
    • 0026347628 scopus 로고
    • Fragile X genotype characterized by an unstable region of DNA
    • (1991) Science , vol.252 , pp. 1179-1181
    • Yu, S.1
  • 7
    • 0025905795 scopus 로고
    • Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in Fragile X syndrome
    • (1991) Cell , vol.65 , pp. 905-914
    • Verkerk, A.J.1
  • 8
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • (1993) Cell , vol.72 , pp. 971-983
  • 9
    • 0027730371 scopus 로고
    • Co-chairman's remarks: Reverse genetics: Directed modification of DNA for functional analysis
    • (1993) Gene , vol.135 , pp. 261-264
    • Berg, P.1
  • 10
    • 0035348633 scopus 로고    scopus 로고
    • The influence of genetic background on spontaneous and genetically engineered mouse models of complex disease
    • (2001) Lab. Anim. , vol.30 , pp. 34-39
    • Linder, C.C.1
  • 13
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.S.1
  • 17
    • 0033786787 scopus 로고    scopus 로고
    • Linkage disequilibrium and the search for complex disease genes
    • (2000) Genome Res. , vol.10 , pp. 1435-1444
    • Jorde, L.B.1
  • 18
    • 0034660559 scopus 로고    scopus 로고
    • Searching for genetic determinants in the new millennium
    • (2000) Nature , vol.405 , pp. 847-856
    • Risch, N.J.1
  • 20
    • 0033772073 scopus 로고    scopus 로고
    • Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
    • (2000) Nat. Genet. , vol.26 , pp. 163-175
    • Horikawa, Y.1
  • 21
    • 0035978651 scopus 로고    scopus 로고
    • Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
    • (2001) Nature , vol.411 , pp. 599-603
    • Hugot, J.P.1
  • 22
    • 0028291210 scopus 로고
    • Linkage between inherited resistance to activated protein C and factor V gene mutation in venous thrombosis
    • (1994) Lancet , vol.343 , pp. 1536-1538
    • Zoller, B.1    Dahlback, B.2
  • 23
    • 0000851370 scopus 로고    scopus 로고
    • Limits to prediction of phenotypes from knowledge of genotypes
    • (2000) Evol. Biol. , vol.32 , pp. 205-224
    • Clark, A.G.1
  • 26
    • 0035399728 scopus 로고    scopus 로고
    • SNP association studies in Alzheimer's disease highlight problems for complex disease analysis
    • (2001) Trends Genet. , vol.17 , pp. 407-413
    • Emahazion, T.1
  • 28
  • 30
    • 0033624575 scopus 로고    scopus 로고
    • The common PPARγ Pro 12Ala polymorphism is associated with decreased risk of type 2 diabetes
    • (2000) Nat. Genet. , vol.26 , pp. 76-80
    • Altshuler, D.1
  • 31
    • 0033772073 scopus 로고    scopus 로고
    • Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
    • (2000) Nat. Genet. , vol.26 , pp. 163-175
    • Orikawa, Y.1
  • 32
    • 0033647217 scopus 로고    scopus 로고
    • The effect of genetic variation in chemokines and their receptors on HIV transmission and progression to AIDS
    • (2000) Immunol. Rev. , vol.177 , pp. 99-111
    • O'Brien, S.J.1    Moore, J.P.2
  • 34
    • 0035895501 scopus 로고    scopus 로고
    • Sequence interpretation. Functional annotation of mouse genome sequences
    • (2001) Science , vol.291 , pp. 1251-1255
    • Nadeau, J.H.1
  • 35
    • 0032922520 scopus 로고    scopus 로고
    • The FlyBase database of the Drosophila genome projects and community literature
    • (1999) Nucleic Acids Res. , vol.27 , pp. 85-88
  • 38
    • 0033529707 scopus 로고    scopus 로고
    • Functional characterization of the Saccharomyces cerevisiae genome by gene deletion and parallel analysis
    • (1999) Science , vol.285 , pp. 901-906
    • Winzeler, E.A.1
  • 39
    • 0034130561 scopus 로고    scopus 로고
    • Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays
    • (2000) Nat. Biotechnol. , vol.18 , pp. 630-634
    • Brenner, S.1
  • 40
    • 0035154452 scopus 로고    scopus 로고
    • Genetic analysis of case/control data using estimated haplotype frequencies: Application toAPOE locus variation and Alzheimer's disease
    • (2001) Genome Res. , vol.11 , pp. 143-151
    • Falin, D.1
  • 41
    • 0033766857 scopus 로고    scopus 로고
    • Cladistic structure within the human lipoprotein lipase gene and its implications for phenotypic association studies
    • (2000) Genetics , vol.156 , pp. 1259-1275
    • Templeton, A.R.1
  • 42
    • 0035827344 scopus 로고    scopus 로고
    • In silico mapping of complex disease-related traits in mice
    • (2001) Science , vol.292 , pp. 1915-1918
    • Grupe, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.