Actin reorganization in airway smooth muscle cells involves G(q) and G(i-2) activation of Rho

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 277, Issue 3 21-3, 1999, Pages

  Hirshman, Carol A ^a   Emala, Charles W ^a  

^a Coll Phys Surgs of Columbia Univ ^*  (United States)

Author keywords

Antisense oligonucleotide; Carbachol; Cell culture; Endothelin 1; G protein; G (i 2); Lysophosphatidic acid

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; CARBACHOL; ENDOTHELIN 1; GUANINE NUCLEOTIDE BINDING PROTEIN; LYSOPHOSPHATIDIC ACID; PERTUSSIS TOXIN; RHO FACTOR;

ARTICLE; CONTROLLED STUDY; CYTOSKELETON; HUMAN; HUMAN CELL; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; TRACHEA MUSCLE;

EID: 0032887392     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1999.277.3.l653     Document Type: Article

References (39)

1. 2+ sensitivity during muscarinic receptor stimulation of airway smooth muscle. Am. J. Physiol. 271 (Lung Cell. Mol. Physiol. 15): L719-L725, 1996.
2. 13 stimulate rho-dependent stress fiber formation and focal adhesion assembly. J. Biol. Chem. 270: 24631-24634, 1995.
3. Cerutis, D. R., M. Nogami, J. L. Anderson, J. D. Churchill, D. J. Romberger, S. I. Rennard, and M. L. Toews. Lysophosphatidic acid and EGF stimulate mitogenesis in human airway smooth muscle cells. Am. J. Physiol. 273 (Lung Cell. Mol. Physiol. 17): L10-L15, 1997.
4. Chardin, P., P. Boquet, P. Madaule, M. R. Popoff, E. J. Rubin, and D. M. Gill. The mammalian G protein rho C is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells. EMBO J. 8: 1087-1092, 1989.
5. 2+ sensitization of tracheal smooth muscle. Am. J. Physiol. 275 (Lung Cell. Mol. Physiol. 19): L748-L755, 1998.
6. 2 receptors and inhibition of adenylyl cyclase in lung. Am. J. Physiol. 268 (Lung Cell. Mol. Physiol. 12): L101-L107, 1995.
7. ras in human airway smooth muscle cells. Am. J. Physiol. 276 (Lung Cell. Mol. Physiol. 20): L564-L570, 1999.
8. Gerthoffer, W. T. Agonist synergism in airway smooth muscle contraction. J. Pharmacol. Exp. Ther. 278: 800-807, 1996.
9. 2+ sensitization of smooth muscle. Proc. Natl. Acad. Sci. USA 93: 1340-1345, 1996.
10. Goto, K., H. Hama, and Y. Kasuyu. Molecular pharmacology and pathophysiological significance of endothelin. Jpn. J. Pharmacol. 72: 261-290, 1996.
11. Ha, K.-S., E.-J. Yeo, and J. H. Exton. Lysophosphatidic acid activation of phosphatidylcholine-hydrolysing phospholipase D and actin polymerization by a pertussis toxin-sensitive mechanism. Biochem. J. 303: 55-59, 1994.
12. Hall, A. Small GTP-binding proteins and the regulation of the actin cytoskeleton. Annu. Rev. Cell Biol. 10: 31-54, 1994.
13. Hall, I. P., and M. Kotlikoff. Use of cultured airway myocytes for study of airway smooth muscle. Am. J. Physiol. 268 (Lung Cell. Mol. Physiol. 12): L1-L11, 1995.
14. Hay, D. W. P., M. A. Luttman, M. Pullen, and P. Nambi. Functional and binding characterization of endothelin receptors in human bronchus: evidence for a novel endothelin B receptor subtype? J. Pharmacol. Exp. Ther. 284: 669-677, 1998.
15. B receptors and multiple signal transduction systems. Br. J. Pharmacol. 110: 435-441, 1993.
16. Hildebrandt, J. D. Role of subunit diversity in signaling by heterotrimeric G proteins. Biochem. Pharmacol. 54: 325-339, 1997.
17. Hirata, K., A. Kikuchi, T. Sasaki, S. Kuroda, K. Kaibuchi, Y. Matsuura, H. Seki, K. Saida, and Y. Takai. Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction. J. Biol. Chem. 267: 8719-8722, 1992.
18. i-2 is required for carbachol-induced stress fiber formation in human airway smooth muscle cells. Am. J. Physiol. 275 (Lung Cell. Mol. Physiol. 19): L911-L916, 1998.
19. Janmey, P. A. The cytoskeleton and cell signaling: component localization and mechanical coupling. Physiol. Rev. 78: 763-781, 1998.
20. Kimura, K., M. Ito, M. Amano, K. Chihara, Y. Fukata, M. Nakafuku, B. Yamamori, J. Feng, T. Nakano, K. Okawa, A. Iwamatsu, and K. Kaibuchi. Regulation of myosin phosphatase by rho and rho-activated kinase (rho-kinase). Science 273: 245-248, 1996.
21. Knowles, G. C., and C. A. G. McCulloch. Simultaneous localization and quantification of relative G and F actin content: optimization of fluorescence labeling methods. J. Histochem. Cytochem. 40: 1605-1612, 1992.
22. Koyama, Y., and A. Baba. Endothelin-induced cytoskeletal actin re-organization in cultured astrocytes: inhibiton by C3 ADP-ribosyltransferase. Glia 16: 342-350, 1996.
23. Kranenburg, O., M. Poland, M. Gebbink, L. Ooomen, and W. H. Moolenaar. Dissociation of LPA-induced cytoskeletal contraction from stress fiber formation by differential localization of Rho A. J. Cell Sci. 110: 2417-2427, 1997.
24. Moolenaar, W. H., O. K. Kranenburg, F. R. Postma, and C. M. Zondag. Lysophosphatidic acid: G-protein signalling and cellular responses. Curr. Opin. Cell Biol. 9: 168-173. 1997.
25. Nobes, C. D., and A. Hall. Rho, rac and cdc42 GTPases: regulators of actin structures, cell adhesion and motility. Biochem. Soc. Trans. 23: 456-459, 1995.
26. Nogami, M., S. M. Whittle, D. J. Romberger, S. I. Rennard, and M. L. Toews. Lysophosphatidic acid regulation of cyclic AMP accumulation in cultured human airway smooth muscle cells. Mol. Pharmacol. 48: 766-773, 1995.
27. Otto, B., A. Steusloff, I. Just, K. Aktories, and G. Pfitzer. Role of Rho proteins in carbachol-induced contractions in intact and permeabilized guinea-pig intestinal smooth muscle. J. Physiol. (Lond.) 496: 317-329, 1996.
28. Ponicke, K. M., M. Vogelsang, M. Heinroth, K. Becker, O. Zolk, M. Bohm, H. Zerkowski, and O.-E. Brodde. Endothelin receptors in the failing and nonfailing human heart. Circulation 97: 744-751, 1998.
29. Ridley, A. J., and A, Hall. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70: 389-399, 1992.
30. 2 receptors in bovine tracheal smooth muscle: discrepancies between binding and function. Eur. J. Pharmacol. 153: 73-82, 1988.
31. Standifer, K. M., G. C. Ross, and G. W. Pasternak. Differential blockade of opioid analgesia by antisense oligodeoxynucleotides directed against various G protein α subunits. Mol. Pharmacol. 50: 293-298, 1996.
32. i2 protein α subunit sequence inhibits an opioid-induced increase in the intracellular free calcium concentration in ND8-47 neuroblastoma x dorsal root ganglion hybrid cells. Mol. Pharmacol. 48: 189-193, 1995.
33. Toews, M. L., E. E. Ustinova, and H. D. Schultz. Lysophosphatidic acid enhances contractility of isolated airway smooth muscle. J. Appl. Physiol. 83: 1216-1222, 1997.
34. i activation of Rho in human airway smooth muscle cells. Am. J. Physiol. 274 (Lung Cell. Mol. Physiol. 18): L803-L809, 1998.
35. ras by G protein-coupled receptor agonists in fibroblasts. Proc. Natl. Acad. Sci. USA 90: 1257-1261, 1993.
36. Vogelsang, M., A. Broede-Sitz, E. Schafer, H.-R. Zerkowski, and O.-E. Brodde. Endothelin ET-A receptors couple to inositol phosphate formation and inhibition of adenylate cyclase in human right atrium. J. Cardiovasc. Pharmacol. 23: 344-347, 1994.
37. 2 receptors in cultured human airway smooth muscle cells. Am. J. Respir. Cell Mol. Biol. 9: 541-546, 1993.
38. Yang, C. M., Y.-L. Yo, R. Ong, and J.-T. Hsieh. Endothelin-and sarafotoxin-induced hydrolysis in cultured canine tracheal smooth muscle cells. J. Neurochem. 62: 1440-1448, 1994.
39. Yoshimura, H., J. Nishimura, C. Sakihara, S. Kobayashi, S. Takahashi, and H. Kanaide. Expression and function of endothelins, endothelin receptors, and endothelin converting enzyme in the porcine trachea. Am. J. Respir. Cell Mol. Biol. 17: 471-480, 1997.