On the role of CD3δ chains in TCR-γδ/CD3 complexes during assembly and membrane expression

Scandinavian Journal of Immunology

Volumn 54, Issue 1-2, 2001, Pages 155-162

  Alibaud, L ^a   Arnaud, J ^a   Llobera, R ^a   Rubin, B ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOTIN; CD3 ANTIGEN; COMPLEMENTARY DNA; CYSTEINE; LYMPHOCYTE ANTIGEN RECEPTOR; METHIONINE; SULFUR 35;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INTRACELLULAR TRANSPORT; LYMPHOMA CELL LINE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE; ANIMAL; CELL MEMBRANE; GENE EXPRESSION; GENETICS; IMMUNOLOGY; LEUKEMIA CELL LINE; MOUSE;

ANIMALS; ANTIGENS, CD3; CELL MEMBRANE; GENE EXPRESSION; HUMANS; JURKAT CELLS; MICE; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA;

EID: 0034743505     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.2001.00938.x     Document Type: Article

References (49)

1. γ/δ cells
2. Structural and functional evolution of the extracellular regions of T cell receptors
3. Activation and function of γ-° T-cells
4. A large subpopulation of avian T cells express a homoloque of the mammalian Tγδ receptor
5. Prominence of γδ T cells in the ruminant immune system
6. Functions of TCR and pre-TCR subunits: Lessons from gene ablation
7. 2-microglobulin deficient mice
8. Positive selection is not required for thymic maturation of transgenic γδ-T cells
9. Stimulation of human γδ T cells by nonpeptidic mycobacterial ligands
10. Human γδ T cells recognize alkylamines derived from microbes, edible plants and tea: Implications for innate immunity
11. Recognition by γδ-T cells
12. An αβ T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex
13. Atomic structure of an αβ T cell receptor (TCR) heterodimer in complex with an anti-TCR Fab fragment derived from a mitogenic antibody
14. Crystal structure of the Vδ domain of a human γδ T cell antigen receptor
15. Structural basis for the specificity of phosphorylcholine-binding immunoglobulins
16. The T cell receptor/CD3 complex: A dynamic protein ensemble
17. Characterization of T cell receptor assembly and expression in a Ti γδ-positive cell line
18. Signal transduction by lymphocyte antigen receptors
19. T cell receptor ζ allows stable expression of receptors containing the CD3γ leucine-based receptor sorting motif
20. The CD3ε subunit of the TCR contains endocytosis signals
21. Assembly of the TCR/CD3 complex: CD3ε/δ and CD3ε/δ dimers associate indistinctly with both TCRα and TCRβ chains. Evidence for a double TCR heterodimer model
22. TCRα-CD3δε association is the initial step in αβ dimer formation in murine T cells and is limiting in immature CD4+CD8+ thymocytes
23. Defective interactions between TCR chains and CD3 heterodimers prevent membrane expression of TCRαβ in human T cells
24. The interchain disulfide bond between T cell receptor-αβ heterodimers on human T cells is not required for TCR/CD3 membrane expression or signal transmission
25. Pairwise, cooperative and inhibitory interactions describe the assembly and probable structure of the T-cell antigen receptor
26. TCRζ is transported to and retained in the Golgi apparatus independently of other TCR chains: Implications for TCR assembly
27. 2 homodimers: Clues from a «phenotypic revertant» clone
28. Structural, comparison of αβ and γδ T cell receptor-CD3 complexes reveals identical subunit interactions but distinct cross-linking patterns of T cell receptor chains
29. Biological function of the extracellular domain of the T-cell receptor constant region
30. The CD3γ chain is essential for development of both the TCRαβ and TCRγδ lineages
31. Altered T cell development in mice with a targeted mutation of the CD3ε gene
32. Specific requirement for CD3ε in T cell development
33. CD3δ deficiency arrests development of the αβ but not the γδ T cell lineage
34. A motif in the αβ T-cell receptor controls positive selection by modulating ERK activity
35. CD3δ couples T-cell receptor signalling to ERK activation and thymocyte positive selection
36. Evidence for a stepwise evolution of the CD3 family
37. An amphibian CD3 homologue of the mammalian CD3γ and CD3δ genes
38. Molecular modeling and endoplasmic reticulum retention of mutated T cell receptor (TCR)/CD3 complexes
39. Vγ2Vδ2 TCR-dependent recognition of non-peptide antigens and Daudi cells analyzed by TCR gene transfer
40. A highly conserved phenylalanine in the α,β-T cell receptor (TCR) constant region determines the integrity of TCR/CD3 complexes
41. Surface expression of functional T cell receptor chains formed by interlocus recombination on human T lymphocytes
42. Dissection of the role of CD3γ chains in profound but reversible T-cell receptor down-regulation
43. A redundant role of the CD3γ-Immunoreceptor tyrosine-based activation motif in mature T cell function
44. Positive selection through a motif in the αβ T cell receptor
45. A motif within the T cell receptor α chain constant region connecting peptide domain controls antigen responsiveness
46. Regulation of pre-T cell receptor gene expression during human thymic development
47. Genomic structure of the human pre-T cell receptor alpha chain and expression of two mRNA isoforms
48. Subunit composition of pre-T cell receptor complexes expressed by primary thymocytes: CD3δ is physically associated but not functionally required
49. Different initiation of pre-TCR and gamma-delta TCR signaling