The kinetics of inactivation of the rod phototransduction cascade with constant Ca2+i

Journal of General Physiology

Volumn 107, Issue 1, 1996, Pages 19-34

  Lyubarsky, A ^a   Nikonov, S ^a,b   Pugh Jr , E N ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b INSTITUTE OF CELL BIOPHYSICS   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM BINDING PROTEIN; CALCIUM ION; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; GUANYLATE CYCLASE; PHOSPHODIESTERASE; PHOSPHOTRANSFERASE; RECOVERIN; RETINA S ANTIGEN; RHODOPSIN;

ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CALCIUM MOBILIZATION; NONHUMAN; PHOTOTRANSDUCTION; PROTEIN PHOSPHORYLATION; RETINA ROD; SALAMANDER;

ANIMALS; CALCIUM; KINETICS; MODELS, THEORETICAL; PHOTIC STIMULATION; RETINA; RODS (RETINA); URODELA;

EID: 0030068240     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.107.1.19     Document Type: Article

References (51)

1. Angleson, J. K., and T. G. Wensel. 1994. Enhancement of rod outer segment GTPase accelerating protein activity by the inhibitory subunit of cGMP phosphodiesterase. J. Biol. Chem. 269:16290-16296.
2. Arshavsky, V. Y., and M. D. Bownds. 1992. Regulation of deactivation of photoreceptor G protein by its target enzyme and cGMP. Nature (Lond.). 357:416-417.
3. Arshavsky, V. Y., C. L. Dumke, and M. D. Bownds. 1992. Non-catalytic cGMP binding sites of amphibian rod cGMP phosphodiesterase control interaction with its inhibitory γ-subunits. A putative regulatory mechanism of the rod photoresponse. J. Biol. Chem., 267:24001-24507.
4. Arshavsky, V. Y., C. L. Dumke, Y. Zhu, N. O. Artemyev, N. P. Skiba, H. E. Hamm, and M. D. Bownds. 1994. Regulation of transducin GTPase activity in bovine rod outer segments. J. Biol. Chem. 269: 19882-19887.
5. Bader, D. R., P. R. MacLeish, and E. A. Schwartz. 1979. A voltageclamp study of the light response in solitary rods of the tiger salamander. J Physiol. (Lond.). 296:1-26.
6. Baylor, D. A., A. L. Hodgkin, and T. D. Lamb. 1974. The electrical response of turtle cones to flashes and steps of light. J. Physiol. (Lond.). 242:685-727.
7. Baylor, D. A., and B. J. Nunn. 1986. Electrical properties of the light-sensitive conductance of rods of the salamander Ambystoma tigrinum. J. Physiol. (Lond.). 371:115-145.
8. Bennett, N., and A. Sitaramayya. 1988. Inactivation of photoexcited rhodopsin in retinal rods: the roles of rhodopsin kinase and 48-dDa protein (Arrestin). Biochemistry. 27:1710-1715.
9. Breton, M. E., A. W. Schueller, T. D. Lamb, and E. N. Pugh, Jr. 1994. Analysis of ERG α-wave amplification and kinetics in terms of the G-protein cascade of phototransduction. Invest. Ophthalmol. Vis. Sci. 35:295-309.
10. i-dependent interaction of recoverin with rhodopsin kinase. J. Biol. Chem. 270:1-7.
11. Cobbs, W. H., and E. N. Pugh, Jr. 1987. Kinetics and components of the flash photocurrent of isolated retinal rods of the larval salamander Ambystona tigrinum. J. Physiol. (Lond.). 394:529-572.
12. Colquhoun, D., and F. J. Sigworth. 1983. Fitting and statistical analysis of single-channel records. In Single-Channel Recording. B. Sakmann and E. Neher, editors. Plenum Publishing Corp., New York.
13. Dumke, C. L., V. Y. Arshavsky, P. D. Calvert, M. D. Bownds, and E. N. Pugh, Jr. 1994. Rod outer segment structure influences the apparent kinetic parameters of cyclic GMP phosphodiesterase. J. Gen. Physiol. 103:1071-1098.
14. Durham, A. C. H. 1983. A survey of readily available chelators for buffering calcium ion concentrations in physiological solutions. Cell Calcium. 4:33-46.
15. Fain, G. L., T. D. Lamb, H. R. Matthews, and R. L. W. Murphy. 1989. Cytoplasmic calcium as the messenger for light adaptation in salamander rods. J. Physiol. (Lond.). 416:215-243.
16. Gorczya, W. A., M. P. Gray-Keller, P. B. Detwiler, and K. Palczewski. 1994. Purification and physiological evaluation of a guanylate cyclase activating protein from retinal rods. Proc. Natl. Acad. Sci. USA. 91:4014-4018.
17. Gray-Keller, M. P., and P. B. Detwiler. 1994. The calcium feedback signal in the phototransduction cascade of vertebrate rods. Neuron. 13:849-861.
18. Hagins, W. A., R. D. Penn, and S. Yoshikami. 1970. Dark current and photocurrent in retinal rods. Biophys. J. 10:380-412.
19. Hays, W. L. 1963. Statistics. Holt, Rinehart and Winston, New York.
20. Hodgkin, A. L., and B. J. Nunn. 1988. Control of light-sensitive current in salamander rods. J. Physiol. (Lond.). 403:439-471.
21. Hodgkin, A. L., P. A. McNaughton, B. J. Nunn, and K.-W. Yau. 1984. Effect of ions on retinal rods from Bufo marinus. J. Physiol. (Lond.). 350:649-680.
22. Hodgkin, A. L., P. A. McNaughton, and B. J. Nunn. 1985. The ionic selectivity and calcium dependence of the light-sensitive pathway in toad rods. J. Physiol. (Lond.). 358:447-468.
23. Hodgkin, A. L., P. A. McNaughton, and B. J. Nunn. 1987. Measurement of sodium-calcium exchange in salamander rods. J. Physiol. (Lond.). 391:347-370.
24. Hofmann, K. P., and M. Heck. 1995. Light-induced protein-protein interactions on the rod photoreceptor disc membrane. In Biomembranes II. Lee, editor. JAI Press.
25. Hood, D. C., and D. G. Birch. 1994. Rod phototransduction in retinitis pigmentosa: estimation and interpretation of parameters derived from the rod α-wave. Invest. Ophthalmol. Vis. Sci. 35:2948-2961.
26. Kahlert, M., D. R. Pepperberg, and K. P. Hofmann. 1990. Effect of bleached rhodopsin on signal amplification in rod visual receptors. Nature (Lond.). 345:537-539.
27. Karpen, J. W., A. L. Zimmerman, L. Suyer, and D. A. Baylor. 1988. Gating kinetics of the cyclic GMP-activated channel of retinal rods: flash photolysis and voltage clamp studies. Proc. Natl Acad. Sci. USA. 85:1287-1291.
28. Kawamura, S. 1993. Rhodopsin phosphorylation as a mechanism of cyclic GMP phosphodiesterase regulation by S-modulin. Nature (Lond.). 362:855-857.
29. Klenchin, V. A., P. D. Calvert, and M. D. Bownds. 1995. Inhibition of rhodopsin kinase by recoverin: evidence for a negative feedback system in phototransduction. J. Biol. Chem. 270:16147-16152.
30. Kraft, T. W., D. M. Schneeweis, and J. L. Schnapf. 1993. Visual transduction in human rod photoreceptors. J. Physiol. (Lond.). 464:747-765.
31. Lagnado, L., and D. A. Baylor. 1994. Calcium controls light-triggered formation of catalytically active rhodopsin. Nature (Lond.). 367:273-277.
32. Lagnado, L., L. Cervetto, and P. A. McNaughton. 1992. Calcium homeostasis in the outer segments of retinal rods from the tiger salamander. J. Physiol. 455:111-142.
33. Lamb, T. D. 1994. Stochastic simulation of activation in the G-protein cascade of phototransduction. Biophys. J. 67:1439-1454.
34. Lamb, T. D., and H. R. Matthews. 1988. Incorporation of analogues of GTP and GDP into rod photoreceptors isolated from the tiger salamander. J. Physiol. (Lond.). 407:463-487.
35. Lamb, T. D., and Pugh, E. N., Jr. 1992. A quantitative account of the activation steps involved in phototransduction in amphibian photoreceptors. J. Physiol. (Lond.). 449:719-758.
36. Matthews, H. R. 1995. Effects of lowered cytoplasmic calcium concentration and light on the responses of salamander rod photoreceptors. J. Physiol. (Lond.) 484:267-286.
37. Matthews, H. R., R. I., W. Murphy, G. L. Fain, and T. D. Lamb. 1988. Photoreceptor light adaptation is mediated by cytoplasmic calcium concentration. Nature (Lond.). 334:67-69.
38. Miller, J. L., and J. I. Korenbrot. 1994. Differences in calcium homeostasis between retinal rod and cone photoreceptors revealed by the effects of voltage on the cGMP-gated conductance in intact cells. J. Gen. Physiol. 104:909-940.
39. Nakatani, K., and K.-W. Yau. 1988. Calcium and light adaptation in retinal rods and cones. Nature (Lond.). 334:69-71.
40. Nakatani, K., and K.-W. Yau. 1989. Sodium-dependent calcium extrusion and sensitivity regulation in retinal cones of the salamander. J. Physiol. (Lond.). 409:525-548.
41. Palczweski, K., I. Subbaraya, W. A. Gorczyca, B. S. Helekar, C. C. Ruiz, H. Phguro. J. Huang, X. Zhao, J. W. Crabb, R. S. Johnson, K. A. Walsh, M. P. Gray-Keller, P. B. Detwiler, and W. Baehr. 1994. Molecular cloning and characterization of retinal photoreceptor guanylyl cyclase-attivating protein. Neuron. 13:1-20.
42. Pepperberg, D. R., M. C. Cornwall, M. Kahlert, K. P. Hofmann, J. Jin, G. J. Jones, and H. Ripps. 1992. Light-dependent delay in the falling phase of the retinal rod photoresponse. Vis. Neurosci. 8:9-18.
43. Pepperberg, D. R., M. Kahlert, A. Krause, and K. P. Hofmann. 1988. Photic modulation of a highly sensitive, near-infrared light-scattering signal recorded from intact retinal photoreceptors. Proc. Natl. Acad Sci. USA. 85:5531-5535.
44. Pugh, E. N., Jr., and T. D. Lamb. 1993. Amplification and kinetics of the activation steps in phototransduction. Biochim. Biophys. Acta. 1141:111-149
45. Ratto, G. M., R Payne, W. G. Owen, and R. Y. Tsien. 1988. The concentration of cytosolic free calcium in vertebrate outer segments measured with fura-2. J. Neurosci. 8:3240-3246.
46. Sitaramayya, A., and P. A. Liebman. 1983. Mechanism of ATP quench of phosphodiesterase activation in rod disc membranes. J. Biol. Chem. 258:1205-1209.
47. Tamura, T., K. Nakatani, and K.-W. Yau. 1991. Calcium feedback and sensitivity regulation in primate rods. J. Gen. Physiol. 98:95-130.
48. Torre, V., H. R Matthews, and T. D. Lamb. 1986. Role of calcium in regulating the cyclic nucleotide cascade of phototransduction in retinal rods. Proc. Natl. Acad. Sci. USA. 83:7109-7113.
49. Tsien, R. Y. 1983. Intracellular measurements of ion activities. Annu. Rev. Biophys. Bioeng. 12:91-116.
50. Wilden, U., S. W. Hall, and H. Kuhn. 1986. Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48 KDa protein of rod outer segments. Proc Natl Acad. Sci. USA 83:1174-1178.
51. Yau, K.-W., and D. A. Baylor. 1989. Cyclic GMP-activated conductance of retinal photoreceptor cells. Anuu. Rev. Neurosci. 12:289-327.