메뉴 건너뛰기




Volumn 90, Issue 1-3, 2000, Pages 27-32

New frontiers in the biology of GLP-2

Author keywords

Enteroendocrine; Inflammatory bowel disease; Nutrition; Peptide; Small intestine; Total parenteral nutrition

Indexed keywords

ADENYLATE CYCLASE; GLUCAGON LIKE PEPTIDE; GLUCAGON LIKE PEPTIDE 2; GLUCAGON RECEPTOR; GLUCOSE TRANSPORTER; UNCLASSIFIED DRUG;

EID: 0034733895     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-0115(00)00117-8     Document Type: Review
Times cited : (61)

References (56)
  • 1
    • 0031936954 scopus 로고    scopus 로고
    • The glucagon-like peptides
    • Drucker D.J. The glucagon-like peptides. Diabetes. 47:1998;159-169.
    • (1998) Diabetes , vol.47 , pp. 159-169
    • Drucker, D.J.1
  • 3
  • 4
    • 0033175006 scopus 로고    scopus 로고
    • An intestinal hormone, signaling nutritional abundance, with an unusual therapeutic potential
    • Holst J.J. An intestinal hormone, signaling nutritional abundance, with an unusual therapeutic potential. Trends Endocrinol. Metabol. 1999;10.
    • (1999) Trends Endocrinol. Metabol. , pp. 10
    • Holst, J.J.1
  • 5
    • 0015139020 scopus 로고
    • Endocrine tumour in kidney affecting small bowel structure, motility, and absorptive function
    • Gleeson M.H., Bloom S.R., Polak J.M., Henry K., Dowling R.H. Endocrine tumour in kidney affecting small bowel structure, motility, and absorptive function. Gut. 12:1971;773-782.
    • (1971) Gut , vol.12 , pp. 773-782
    • Gleeson, M.H.1    Bloom, S.R.2    Polak, J.M.3    Henry, K.4    Dowling, R.H.5
  • 6
    • 0021271224 scopus 로고
    • Glucagonoma syndrome demonstrating giant duodenal villi
    • Stevens F.M., Flanagan R.W., O'Gorman D., Buchanan K.D. Glucagonoma syndrome demonstrating giant duodenal villi. Gut. 25:1984;784-791.
    • (1984) Gut , vol.25 , pp. 784-791
    • Stevens, F.M.1    Flanagan, R.W.2    O'Gorman, D.3    Buchanan, K.D.4
  • 7
    • 0020315831 scopus 로고
    • Small bowel adaptation and its regulation
    • Dowling R.H. Small bowel adaptation and its regulation. Scand. J. Gastroenterol. 17:1982;53-74.
    • (1982) Scand. J. Gastroenterol. , vol.17 , pp. 53-74
    • Dowling, R.H.1
  • 8
    • 0020326115 scopus 로고
    • The hormonal pattern of intestinal adaptation [a major role for enteroglucagon]
    • Bloom S.R., Polak J.M. The hormonal pattern of intestinal adaptation [a major role for enteroglucagon]. Scand. J. Gastroenterol. 17:1982;93-103.
    • (1982) Scand. J. Gastroenterol. , vol.17 , pp. 93-103
    • Bloom, S.R.1    Polak, J.M.2
  • 12
    • 0024517967 scopus 로고
    • Plasma enteroglucagon, peptide YY and gastrin in rats deprived of luminal nutrition, and after urogastrone-EGF administration: A proliferative role for PYY in the intestinal epithelium
    • Goodlad R.A., Ghatei M.A., Domin J., Bloom S.R., Gregory H., Wright N.A. Plasma enteroglucagon, peptide YY and gastrin in rats deprived of luminal nutrition, and after urogastrone-EGF administration: a proliferative role for PYY in the intestinal epithelium. Experientia. 45:1989;168-169.
    • (1989) Experientia , vol.45 , pp. 168-169
    • Goodlad, R.A.1    Ghatei, M.A.2    Domin, J.3    Bloom, S.R.4    Gregory, H.5    Wright, N.A.6
  • 13
    • 0026317307 scopus 로고
    • Glucagon 1-21 reduces intestinal epithelial cell proliferation in parenterally fed rats
    • Goodlad R.A., Ghatei M.A., Bloom S.R., Wright N.A. Glucagon 1-21 reduces intestinal epithelial cell proliferation in parenterally fed rats. Exp. Physiology. 76:1991;943-949.
    • (1991) Exp. Physiology , vol.76 , pp. 943-949
    • Goodlad, R.A.1    Ghatei, M.A.2    Bloom, S.R.3    Wright, N.A.4
  • 14
    • 0025316890 scopus 로고
    • Ileal glucagon gene expression: Ontogeny and response to massive small bowel resection
    • Taylor R.G., Verity K., Fuller P.J. Ileal glucagon gene expression: ontogeny and response to massive small bowel resection. Gastroenterology. 99:1990;724-729.
    • (1990) Gastroenterology , vol.99 , pp. 724-729
    • Taylor, R.G.1    Verity, K.2    Fuller, P.J.3
  • 15
    • 0027505792 scopus 로고
    • Ileal proglucagon gene expression in the rat: Characterization in intestinal adaptation using in situ hybridization
    • Fuller P.J., Beveridge D.J., Taylor R.G. Ileal proglucagon gene expression in the rat: characterization in intestinal adaptation using in situ hybridization. Gastroenterology. 104:1993;459-466.
    • (1993) Gastroenterology , vol.104 , pp. 459-466
    • Fuller, P.J.1    Beveridge, D.J.2    Taylor, R.G.3
  • 16
    • 0029924514 scopus 로고    scopus 로고
    • Increased ileal proglucagon expression after jejunectomy is not suppressed by inhibition of bowel growth
    • Ulshen M.H., Hoyt E.C., Fuller C.R., Ghatei M.A., Bloom S.R., Lund P.K. Increased ileal proglucagon expression after jejunectomy is not suppressed by inhibition of bowel growth. Dig. Dis. Sci. 41:1996;677-683.
    • (1996) Dig. Dis. Sci. , vol.41 , pp. 677-683
    • Ulshen, M.H.1    Hoyt, E.C.2    Fuller, C.R.3    Ghatei, M.A.4    Bloom, S.R.5    Lund, P.K.6
  • 17
    • 0029795016 scopus 로고    scopus 로고
    • Induction of intestinal epithelial proliferation by glucagon-like peptide-2
    • Drucker D.J., Ehrlich P., Asa S.L., Brubaker P.L. Induction of intestinal epithelial proliferation by glucagon-like peptide-2. Proc. Natl. Acad. Sci. USA. 93:1996;7911-7916.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7911-7916
    • Drucker, D.J.1    Ehrlich, P.2    Asa, S.L.3    Brubaker, P.L.4
  • 18
    • 0030012124 scopus 로고    scopus 로고
    • Role of prohormone convertases in the tissue-specific processing of proglucagon
    • Dhanvantari S., Seidah N.G., Brubaker P.L. Role of prohormone convertases in the tissue-specific processing of proglucagon. Mol. Endocrinol. 10:1996;342-355.
    • (1996) Mol. Endocrinol. , vol.10 , pp. 342-355
    • Dhanvantari, S.1    Seidah, N.G.2    Brubaker, P.L.3
  • 19
    • 0029925365 scopus 로고    scopus 로고
    • Evidence for redundancy in propeptide/prohormone convertase activities in processing proglucagon: An antisense study
    • Rothenberg M.E., Eilertson C.D., Klein K., Mackin R.B., Noe B.D. Evidence for redundancy in propeptide/prohormone convertase activities in processing proglucagon: an antisense study. Mol. Endocrinol. 10:1996;331-341.
    • (1996) Mol. Endocrinol. , vol.10 , pp. 331-341
    • Rothenberg, M.E.1    Eilertson, C.D.2    Klein, K.3    Mackin, R.B.4    Noe, B.D.5
  • 20
    • 0033305618 scopus 로고    scopus 로고
    • Proglucagon processing profile in canine L cells expressing endogenous prohormone convertase 1/3 and prohormone convertase 2
    • Damholt A.B., Buchan A.M., Holst J.J., Kofod H. Proglucagon processing profile in canine L cells expressing endogenous prohormone convertase 1/3 and prohormone convertase 2. Endocrinology. 140:1999;4800-4808.
    • (1999) Endocrinology , vol.140 , pp. 4800-4808
    • Damholt, A.B.1    Buchan, A.M.2    Holst, J.J.3    Kofod, H.4
  • 21
    • 0022509255 scopus 로고
    • Cellular localization of proglucagon/glucagon-like peptide I messenger RNAs in rat brain
    • Han V.K.M., Hynes M.A., Jin C., Towle A.C., Lauder J.M., Lund P.K. Cellular localization of proglucagon/glucagon-like peptide I messenger RNAs in rat brain. J. Neurosi. Res. 16:1986;97-107.
    • (1986) J. Neurosi. Res. , vol.16 , pp. 97-107
    • Han, V.K.M.1    Hynes, M.A.2    Jin, C.3    Towle, A.C.4    Lauder, J.M.5    Lund, P.K.6
  • 22
    • 0023787950 scopus 로고
    • Glucagon gene expression in vertebrate brain
    • Drucker D.J., Asa S. Glucagon gene expression in vertebrate brain. J. Biol. Chem. 263:1988;13475-13478.
    • (1988) J. Biol. Chem. , vol.263 , pp. 13475-13478
    • Drucker, D.J.1    Asa, S.2
  • 23
    • 0030782159 scopus 로고    scopus 로고
    • Circulating and tissue forms of the intestinal growth factor, glucagon-like peptide-2
    • Brubaker P.L., Crivici A., Izzo A., Ehrlich P., Tsai C.-H., Drucker D.J. Circulating and tissue forms of the intestinal growth factor, glucagon-like peptide-2. Endocrinology. 138:1997;4837-4843.
    • (1997) Endocrinology , vol.138 , pp. 4837-4843
    • Brubaker, P.L.1    Crivici, A.2    Izzo, A.3    Ehrlich, P.4    Tsai, C.-H.5    Drucker, D.J.6
  • 24
    • 0033970249 scopus 로고    scopus 로고
    • Enzymatic and renal-dependent catabolism of the intestinotropic hormone glucagon-like peptide-2 in the rat
    • Tavares W., Drucker D.J., Brubaker P.L. Enzymatic and renal-dependent catabolism of the intestinotropic hormone glucagon-like peptide-2 in the rat. Am. J. Physiol. 278:(1):2000;E134-E139.
    • (2000) Am. J. Physiol. , vol.278 , Issue.1 , pp. 134-E139
    • Tavares, W.1    Drucker, D.J.2    Brubaker, P.L.3
  • 26
    • 0031417543 scopus 로고    scopus 로고
    • Intestinal response to growth factors administered alone or in combination with h[Gly2]-glucagon-like peptide-2
    • Drucker D.J., Deforest L., Brubaker P.L. Intestinal response to growth factors administered alone or in combination with h[Gly2]-glucagon-like peptide-2. Am. J. Physiol. 273:1997;G1252-G1262.
    • (1997) Am. J. Physiol. , vol.273 , pp. 1252-G1262
    • Drucker, D.J.1    Deforest, L.2    Brubaker, P.L.3
  • 27
    • 0023104848 scopus 로고
    • Radio-immunoassays for glucagon-like peptides-1 and -2 (GLP-1 and GLP-2)
    • Orskov C., Holst J.J. Radio-immunoassays for glucagon-like peptides-1 and -2 (GLP-1 and GLP-2). Scand. J. Clin. Lab. Invest. 47:1987;165-174.
    • (1987) Scand. J. Clin. Lab. Invest. , vol.47 , pp. 165-174
    • Orskov, C.1    Holst, J.J.2
  • 28
    • 0033028489 scopus 로고    scopus 로고
    • Secretion of the intestinotropic hormone glucagon-like peptide 2 is differentially regulated by nutrients in humans
    • Xiao Q., Boushey R.P., Drucker D.J., Brubaker P.L. Secretion of the intestinotropic hormone glucagon-like peptide 2 is differentially regulated by nutrients in humans. Gastroenterology. 117:1999;99-105.
    • (1999) Gastroenterology , vol.117 , pp. 99-105
    • Xiao, Q.1    Boushey, R.P.2    Drucker, D.J.3    Brubaker, P.L.4
  • 29
    • 0032885117 scopus 로고    scopus 로고
    • Impaired meal-stimulated glucagon-like peptide-2 response in ileal resected short bowel patients with intestinal failure
    • Jeppesen P.B., Hartmann B., Hansen B.S., Thulesen J., Holst J.J., Mortensen P.B. Impaired meal-stimulated glucagon-like peptide-2 response in ileal resected short bowel patients with intestinal failure. Gut. 45:1999;559-563.
    • (1999) Gut , vol.45 , pp. 559-563
    • Jeppesen, P.B.1    Hartmann, B.2    Hansen, B.S.3    Thulesen, J.4    Holst, J.J.5    Mortensen, P.B.6
  • 30
    • 0027303167 scopus 로고
    • Regulation of intestinal proglucagon-derived peptide secretion by glucose-dependent insulinotropic peptide in a novel enteroendocrine loop
    • Roberge J.N., Brubaker P.L. Regulation of intestinal proglucagon-derived peptide secretion by glucose-dependent insulinotropic peptide in a novel enteroendocrine loop. Endocrinology. 133:1993;233-240.
    • (1993) Endocrinology , vol.133 , pp. 233-240
    • Roberge, J.N.1    Brubaker, P.L.2
  • 31
    • 0032982267 scopus 로고    scopus 로고
    • Role of the vagus nerve in mediating proximal nutrient-induced glucagon-like peptide-1 secretion
    • Rocca A.S., Brubaker P.L. Role of the vagus nerve in mediating proximal nutrient-induced glucagon-like peptide-1 secretion. Endocrinology. 140:1999;1687-1694.
    • (1999) Endocrinology , vol.140 , pp. 1687-1694
    • Rocca, A.S.1    Brubaker, P.L.2
  • 33
    • 0026751401 scopus 로고
    • Nutrient-independent increases in proglucagon and ornithine decarboxylase messenger RNAs after jejunoileal resection
    • Rountree D.B., Ulshen M.H., Selub S., Fuller C.R., Bloom S.R., Ghatei M.A., Lund P.K. Nutrient-independent increases in proglucagon and ornithine decarboxylase messenger RNAs after jejunoileal resection. Gastroenterology. 103:1992;462-468.
    • (1992) Gastroenterology , vol.103 , pp. 462-468
    • Rountree, D.B.1    Ulshen, M.H.2    Selub, S.3    Fuller, C.R.4    Bloom, S.R.5    Ghatei, M.A.6    Lund, P.K.7
  • 34
    • 0033998750 scopus 로고    scopus 로고
    • Circulating levels of glucagon-like peptide-2 in human subjects with inflammatory bowel disease
    • Xiao Q., Boushey R.P., Cino M., Drucker D.J., Brubaker P.L. Circulating levels of glucagon-like peptide-2 in human subjects with inflammatory bowel disease. Am J Physiol. 278:2000;R1057-R1063.
    • (2000) Am J Physiol , vol.278 , pp. 1057-R1063
    • Xiao, Q.1    Boushey, R.P.2    Cino, M.3    Drucker, D.J.4    Brubaker, P.L.5
  • 35
    • 0032621235 scopus 로고    scopus 로고
    • Human [Gly2]-GLP-2 reduces the severity of colonic injury in a murine model of experimental colitis
    • Drucker D.J., Yusta B., Boushey R.P., Deforest L., Brubaker P.L. Human [Gly2]-GLP-2 reduces the severity of colonic injury in a murine model of experimental colitis. Am. J. Physiol. 276:1999;G79-G91.
    • (1999) Am. J. Physiol. , vol.276 , pp. 79-G91
    • Drucker, D.J.1    Yusta, B.2    Boushey, R.P.3    Deforest, L.4    Brubaker, P.L.5
  • 36
    • 0030759264 scopus 로고    scopus 로고
    • Intestinal growth-promoting properties of glucagon-like peptide-2 in mice
    • Tsai C.-H., Hill M., Asa S.L., Brubaker P.L., Drucker D.J. Intestinal growth-promoting properties of glucagon-like peptide-2 in mice. Am. J. Physiol. 273:1997;E77-E84.
    • (1997) Am. J. Physiol. , vol.273 , pp. 77-E84
    • Tsai, C.-H.1    Hill, M.2    Asa, S.L.3    Brubaker, P.L.4    Drucker, D.J.5
  • 37
    • 0032906822 scopus 로고
    • Glucagon-like peptide-2 enhances small intestinal absorptive function and mucosal mass in vivo
    • Kato Y., Yu D., Schwartz M.Z. Glucagon-like peptide-2 enhances small intestinal absorptive function and mucosal mass in vivo. J. Pediatr. Surg. 34:(18-20):1994;20-21.
    • (1994) J. Pediatr. Surg. , vol.34 , Issue.1820 , pp. 20-21
    • Kato, Y.1    Yu, D.2    Schwartz, M.Z.3
  • 40
    • 0032716433 scopus 로고    scopus 로고
    • Diabetic intestinal growth adaptation and glucagon-like peptide-2 in the rat: Effects of dietary fibre
    • Thulesen J., Hartmann B., Nielsen C., Holst J.J., Poulsen S.S. Diabetic intestinal growth adaptation and glucagon-like peptide-2 in the rat: effects of dietary fibre. Gut. 45:1999;672-678.
    • (1999) Gut , vol.45 , pp. 672-678
    • Thulesen, J.1    Hartmann, B.2    Nielsen, C.3    Holst, J.J.4    Poulsen, S.S.5
  • 41
    • 0030667820 scopus 로고    scopus 로고
    • Intestinal growth is associated with elevated levels of glucagon-like peptide-2 in diabetic rats
    • Fischer K.D., Dhanvantari S., Drucker D.J., Brubaker P.L. Intestinal growth is associated with elevated levels of glucagon-like peptide-2 in diabetic rats. Am. J. Physiol. 273:1997;E815-E820.
    • (1997) Am. J. Physiol. , vol.273 , pp. 815-E820
    • Fischer, K.D.1    Dhanvantari, S.2    Drucker, D.J.3    Brubaker, P.L.4
  • 42
    • 0030977884 scopus 로고    scopus 로고
    • Biological determinants of intestinotrophic properties of GLP-2 in vivo
    • Tsai C.-H., Hill M., Drucker D.J. Biological determinants of intestinotrophic properties of GLP-2 in vivo. Am. J. Physiol. 272:1997;G662-G668.
    • (1997) Am. J. Physiol. , vol.272 , pp. 662-G668
    • Tsai, C.-H.1    Hill, M.2    Drucker, D.J.3
  • 43
    • 0030795767 scopus 로고    scopus 로고
    • Intestinal function in mice with small bowel growth induced by glucagon-like peptide-2
    • Brubaker P.L., Izzo A., Hill M., Drucker D.J. Intestinal function in mice with small bowel growth induced by glucagon-like peptide-2. Am. J. Physiol. 272:1997;E1050-E1058.
    • (1997) Am. J. Physiol. , vol.272 , pp. 1050-E1058
    • Brubaker, P.L.1    Izzo, A.2    Hill, M.3    Drucker, D.J.4
  • 47
    • 0021691124 scopus 로고
    • Human glucagon-like peptides-1 and -2 activate rat brain adenylate cyclase
    • Hoosein N.M., Gurd R.S. Human glucagon-like peptides-1 and -2 activate rat brain adenylate cyclase. FEBS Lett. 178:1984;83-86.
    • (1984) FEBS Lett. , vol.178 , pp. 83-86
    • Hoosein, N.M.1    Gurd, R.S.2
  • 48
    • 0030805335 scopus 로고    scopus 로고
    • Prevention of parenteral nutrition-induced gut hyoplasia by coinfusion of glucagon-like peptide-2
    • Chance W.T., Foley-Nelson T., Thomas I., Balasubramaniam A. Prevention of parenteral nutrition-induced gut hyoplasia by coinfusion of glucagon-like peptide-2. Am. J. Physiol. 273:1997;G559-G563.
    • (1997) Am. J. Physiol. , vol.273 , pp. 559-G563
    • Chance, W.T.1    Foley-Nelson, T.2    Thomas, I.3    Balasubramaniam, A.4
  • 49
    • 0031735064 scopus 로고    scopus 로고
    • GLP-2 augments the adaptive response to massive intestinal resection in rat
    • Scott R.B., Kirk D., MacNaughton W.K., Meddings J.B. GLP-2 augments the adaptive response to massive intestinal resection in rat. Am. J. Physiol. 275:1998;G911-G921.
    • (1998) Am. J. Physiol. , vol.275 , pp. 911-G921
    • Scott, R.B.1    Kirk, D.2    MacNaughton, W.K.3    Meddings, J.B.4
  • 50
    • 0032714919 scopus 로고    scopus 로고
    • Glucagon-like peptide-2 decreases mortality and reduces the severity of indomethacin-induced murien enteritis
    • Boushey R.P., Yusta B., Drucker D.J. Glucagon-like peptide-2 decreases mortality and reduces the severity of indomethacin-induced murien enteritis. Am. J. Physiol. 277:1999;E937-E947.
    • (1999) Am. J. Physiol. , vol.277 , pp. 937-E947
    • Boushey, R.P.1    Yusta, B.2    Drucker, D.J.3
  • 51
    • 0033964619 scopus 로고    scopus 로고
    • Glucagon-like peptide-2 analogue enhances intestinal mucosal mass after ischemia and reperfusion
    • Prasad R., Alavi K., Schwartz M.Z. Glucagon-like peptide-2 analogue enhances intestinal mucosal mass after ischemia and reperfusion. J. Pediatr. Surg. 35:2000;357-359.
    • (2000) J. Pediatr. Surg. , vol.35 , pp. 357-359
    • Prasad, R.1    Alavi, K.2    Schwartz, M.Z.3
  • 53
    • 0028325376 scopus 로고
    • Divergent tissue-specific and developmental expression of receptors for glucagon and glucagon-like peptide-1 in the mouse
    • Campos R.V., Lee Y.C., Drucker D.J. Divergent tissue-specific and developmental expression of receptors for glucagon and glucagon-like peptide-1 in the mouse. Endocrinology. 134:1994;2156-2164.
    • (1994) Endocrinology , vol.134 , pp. 2156-2164
    • Campos, R.V.1    Lee, Y.C.2    Drucker, D.J.3
  • 54
    • 0030013475 scopus 로고    scopus 로고
    • Tissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptor
    • Bullock B.P., Heller R.S., Habener J.F. Tissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptor. Endocrinology. 137:1996;2968-2978.
    • (1996) Endocrinology , vol.137 , pp. 2968-2978
    • Bullock, B.P.1    Heller, R.S.2    Habener, J.F.3
  • 55
    • 0029120207 scopus 로고
    • Glucagon receptor mRNA distribution in rat tissues
    • Hansen L.H., Abrahamsen N., Nishimura E. Glucagon receptor mRNA distribution in rat tissues. Peptides. 16:1995;1163-1166.
    • (1995) Peptides , vol.16 , pp. 1163-1166
    • Hansen, L.H.1    Abrahamsen, N.2    Nishimura, E.3
  • 56
    • 0032718059 scopus 로고    scopus 로고
    • Identification of glucagon-like peptide-2 (GLP-2)-activated signaling pathways in baby hamster kidney fibroblasts expressing the rat GLP-2 receptor
    • Yusta B., Somwar R., Wang F., Munroe D., Grinstein S., Klip A., Drucker D.J. Identification of glucagon-like peptide-2 (GLP-2)-activated signaling pathways in baby hamster kidney fibroblasts expressing the rat GLP-2 receptor. J. Biol. Chem. 274:1999;30 459-30 467.
    • (1999) J. Biol. Chem. , vol.274 , pp. 30459-30467
    • Yusta, B.1    Somwar, R.2    Wang, F.3    Munroe, D.4    Grinstein, S.5    Klip, A.6    Drucker, D.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.