Analysis of antibody A6 binding to the extracellular interferon γ receptor α-chain by alanine-scanning mutagenesis and random mutagenesis with phage display

Biochemistry

Volumn 39, Issue 51, 2000, Pages 15674-15685

  Lang, S ^a   Xu, J ^a   Stuart, F ^a   Thomas, R M ^b   Vrijbloed, J W ^a   Robinson, J A ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUND; EPITOPE; FIBRONECTIN; GAMMA INTERFERON RECEPTOR; HISTIDINE; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY A6; MUTANT PROTEIN; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG;

ALPHA CHAIN; ARTICLE; CRYSTAL STRUCTURE; LIGAND BINDING; PHAGE DISPLAY; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

ALANINE; AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; BACTERIOPHAGE M13; BASE SEQUENCE; BINDING SITES, ANTIBODY; BIOSENSING TECHNIQUES; CIRCULAR DICHROISM; CLONING, MOLECULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR SPACE; GENOMIC LIBRARY; IMMUNOGLOBULIN FRAGMENTS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, INTERFERON;

EID: 0034719147     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi000838z     Document Type: Article

References (49)