Tests for linkage and association in nuclear families

American Journal of Human Genetics

Volumn 61, Issue 2, 1997, Pages 439-448

  Martin, E R ^a,b   Kaplan, N L ^a   Weir, B S ^b  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DISEASE PREDISPOSITION; FAMILY; GENE LINKAGE DISEQUILIBRIUM; GENETIC MARKER; PENETRANCE; PRIORITY JOURNAL;

EID: 0030772982     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/514860     Document Type: Article

References (7)

1. Cleves MA, Olson JM, Jacobs KB. Exact transmission-disequilibrium tests for candidate gene testing and genomic screening with multiallelic markers. Genet Epidemiol (in press)
2. Copeman JB, Cucca F, Hearne CM, Cornall RJ, Reed PW, Ronningen KS, Undlien DE, et al (1995) Linkage disequilibrium mapping of a type 1 diabetes susceptibility gene (IDDM7) to chromosome 2q31-q33. Nat Genet 9:80-85
3. Graybill FA (1961) An introduction to linear statistical models. McGraw-Hill, New York
4. Kaplan NL, Martin ER, Weir BS (1997) Power studies for the transmission/disequilibrium tests with multiple alleles. Am J Hum Genet 60:691-702
5. Spielman RS, Ewens WJ (1996) The TDT and other family-based tests for linkage disequilibrium and association. Am J Hum Genet 59:983-989
6. Spielman RS, McGinnis RE, Ewens WJ (1993) Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 52:506-516
7. Wang S, Detera-Wadleigh SD, Coon H, Sun C-e, Goldin LR, Duffy DL, Byerley WF, et al (1996) Evidence of linkage disequilibrium between schizophrenia and the SCA1 CAG repeat on chromosome 6p23. Am J Hum Genet 59:731-736